Abstract：
:Accurate diagnosis and proper monitoring of cancer patients remain important obstacles for successful cancer treatment. The search for cancer biomarkers is carried out in order to quickly identify tumor cells and predict treatment response, ultimately leading to a favorable therapeutic outcome. One such prognostic marker seems to be survivin. Many studies have shown that survivin is strongly expressed in a vast majority of cancers. Its overexpression was demonstrated in breast and lung cancer prostate, gastric, colon, bladder and esophageal carcinomas, osteosarcomas, and lymphomas. In many of those tumors, high activity of the surviving gene was associated with a poor prognosis and worse survival rates. Moreover survivin expression was correlated with resistance to chemotherapy and radiotherapy-induced apoptosis. Since survivin may be identified as an independent prognostic factor and inhibitor of apoptosis, it may prove to be a useful therapeutic target in cancer therapy
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Waligórska-Stachura J,Jankowska A,Waśko R,Liebert W,Biczysko M,Czarnywojtek A,Baszko-Błaszyk D,Shimek V,Ruchała Msubject
Has Abstractpub_date
2012-07-01 00:00:00pages
537-40issue
7eissn
0017-0011issn
2543-6767journal_volume
83pub_type
杂志文章,评审abstract：:The paper concerns the treatment results of 113 women with PCO-S by laparoscopic (102) and microlaparoscopic (11) ovarian electrocautery. All of them were qualified for operation on the basis of the following criteria: menstrual cycle disturbances (oligo-/amenorrhoea), anovulation, hirsutism, obesity, LH/FSH ratio > 2...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：2001-08-01 00:00:00
abstract：:Transvaginal ultrasound scanning was performed on 59 years old women with postmenopausal bleeding in anamnesis. Endometrial thickness was measured at its maximum in both longitudinal and transverse sections of the uterus. Also the thickness of uterus walls and ovaries in 3 planes were measured. Endometrium was irregul...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：METHOD AND RESULTS:Between 1993 and 2000, 7529 patients underwent cesarean section (24.3% of 31,798 delivering women) at University Hospital in Poznań. There were 52 cases of simultaneous adnexal surgery among them because of ovarian tumors (1 case/144 abdominal deliveries; 1 case/612 pregnancies). In 43 cases tumor wa...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2002-04-01 00:00:00
abstract：:Concentrations of iron, zinc and copper were determined in public hair of women with threatened abortion and in full-term pregnancy. The aim of the studies was to find differences between the levels of studied elements in public hair of women with threatened abortion and in full-term pregnancy and to test whether pari...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-07-01 00:00:00
abstract：:Childhood and adolescent gynecology is an emerging specialty at the intersection of pediatrics, pediatric endocrinology gynecology pediatric surgery dermatology psychiatry, public health medicine and genetics, and in fact addresses many legal issues. Poland lacks a uniform standing of medical and legal environments on...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：10.17772/gp/1553
更新日期：2013-02-01 00:00:00
abstract：OBJECTIVES:The goal of this study was to evaluate the frequency of Sp1 +1245G>T (rs 1800012) and -199 7G>T (rs 1107946) COL1A1 gene polymorphisms in postmenopausal women with osteoporosis and osteopenia as well as assessing their relations with the clinical parameters and parameters of bone turnover. STUDY DESIGN:The ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/60550
更新日期：2015-12-01 00:00:00
abstract：:We investigated the vitamin D receptor (VDR) and the estrogen receptor (ER) genes polymorphism in studied groups was similar, however the allelic combination BBPPxx was associated with low bone mineral mass. There is a need to perform genetic test in the cohort of polish women endangered by osteoporosis. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-08-01 00:00:00
abstract：:Thrombotic thrombocytopenic purpura (TTP) is characterized by microangiopathic hemolytic anemia and thrombocytopenia, accompanied by microvascular thrombosis that causes variable degrees of tissue ischemia and infarction. About 10-20% of TTP cases are associated with the pregnancy. Preterm delivery and intrauterine fe...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2008-07-01 00:00:00
abstract：:During 14 subsequent days male Wistar rats received subcutaneously 50 micrograms of EB and different doses of tamoxifen intratesticularly. Action of EB was examined by comparison with the group, which received the solvent for EB only. EB caused the reduction in the mean testis weight, degenerative changes of germinal ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1994-02-01 00:00:00
abstract：OBJECTIVES:The aim of the following study was to assess antisperm antibodies in sera samples of infertile men and women, as well as from prepubertal boys by means of flow cytometry. MATERIAL AND METHODS:We tested sera samples of infertile and fertile adult populations, prepubertal boys with gonadal disorders and healt...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2010-08-01 00:00:00
abstract：OBJECTIVES:Gestational diabetes mellitus is a carbohydrate intolerance that occurs during pregnancy. Various inflammatory mediators are considered to be risk factors leading to GDM development. Among them are pro-inflammatory cytokines, such as IL16 and IL18. The aim of this study was to examine the association between...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2017.0047
更新日期：2017-01-01 00:00:00
abstract：:Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age. It is manifested by hyperandrogenism, polycystic ovaries on ultrasound, oligomenorrhoea and anovulation. PCOS patients are more vulnerable to metabolic disorders: insulin resistance, obesity endothelium dysfunction, athero...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2015-04-01 00:00:00
abstract：:The authors evaluated the influence of NAD, NADP, G-6-P and G-6-PDH on the synthesis of steroid hormones in the interstitial gland of the rat. The animals were killed by decapitation, and sections of the nucleus weighing altogether 20 mg were incubated with NAD (0.4 mM), NADP (0.4 mM), G-6-P (3.5 mM) and G-6-PDH (2 j....
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1989-05-01 00:00:00
abstract：OBJECTIVES:Therapeutic hypothermia TH became broadly used in the management of the asphyxiated newborns. Although two cooling methods are used, so far the superiority of none of them has been established. The purpose of the study is to compare two cooling methods: selective head cooling (SHC) and whole body cooling (WB...
journal_title：Ginekologia polska
pub_type： 杂志文章,多中心研究
doi：10.5603/GP.2019.0069
更新日期：2019-01-01 00:00:00
abstract：:The aim of the work were changes of serum ferritin and iron concentrations in women with leiomyoma of the uterus treated surgically. We took the growth of the leiomyomatous uterus under concern. We observed the lower serum ferritin and iron concentrations before the surgical treatment, and the correlation with the gro...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
abstract：OBJECTIVES:The purpose of our study was to determine maternal serum concentrations of IL-8, IL-6, IFN-gamma during normal pregnancy and labor. MATERIALS AND METHODS:Maternal serum IL-8, IL-6 and IFN-gamma levels were measured by means of ELISA technique in 41 healthy pregnant women in 22-42 week gestation and 15 healt...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：OBJECTIVES:Acute puerperal uterine inversion is a rare but very feared obstetrical complication. It determines an almost immediate shock and serious metrorrhagia. It is a introflexion of parietes uteri which takes place during the third stage of labor or during the first hours of puerperium. It can be distinguished in ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-11-01 00:00:00
abstract：:The authors describe diagnostic difficulties connected with proper estimation of stromal sarcoma biological activities, which developed in uterus corpus in 18 year old girl previously treated with hormones, because of irregular painful menses. Macroscopic and microscopic investigations of postoperative specimen allowe...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：AIM:To evaluate the a-chemokine stromal cell-derived factor-1 (SDF-1)/CXCL12 levels in the peritoneal fluid (PF) and plasma of patients with epithelial ovarian cancer (EOC, n=101), serous cyst (n=34) or normal controls (n=20). SDF-1alpha concentrations were correlated to myeloid (M) and lymphoid (L) dendritic cells (DC...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2011-06-01 00:00:00
abstract：:576 patients with preterm deliveries that occurred between the 22nd to 37th gestation weeks were undergone clinical analysis. The material was collected in the years 1995 to 1999 at Clinic of Obstetric and Perinatology of Pomeranian Academy of Medicine in Szczecin. In our study the rate of preterm delivery was 10.5%. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-08-01 00:00:00
abstract：OBJECTIVES:The study aimed to assess the associations between circulating vaspin levels and nutritional status (assessed on tha basis of BMI) as well as insulin resistance in PCOS. MATERIAL AND METHODS:Eighty-seven PCOS women, 48 obese and 39 normal weight, were enrolled in the cross-sectional study. Seventy-two Non-P...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2020.0056
更新日期：2020-01-01 00:00:00
abstract：:We present a case of a female neonate, born at 36 weeks of gestation from a monochorionic, diamniotic spontaneous twin pregnancy with congenital epulis, 2.5 cm in size, protruding from the oral cavity. Histopathology revealed a typical granular cell lesion. The other twin, also female, was prenatally diagnosed with co...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1633
更新日期：2013-08-01 00:00:00
abstract：:Intrauterine growth retardation (IUGR) increases a risk of perinatal complications and may carry a negative influence on a later baby's mental and physical development. Poorer function revealed by many vital organs seems to be the effect of their lower mass and their relative immaturity. In the first part of a paper t...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2004-04-01 00:00:00
abstract：INTRODUCTION:A standard assessment of embryo morphology at given time points does not always allow to transfer the embryo with the highest implantation potential. The effect of transfer of an improper embryo results in a lack of pregnancy or a miscarriage and, as a consequence, exposes the patient to unnecessary emotio...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1728
更新日期：2014-04-01 00:00:00
abstract：:We present a case report of a 37-year-old woman with accidental finding of two IUDs--one inserted correctly and the other one located in the abdomen. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2011-02-01 00:00:00
abstract：:The terminology quoted in the leaflet "Ultrasonometry of foetus in evaluation of gestational age" could change the diagnostic and therapeutic procedures in obstetrics from the point of view of only one out of many methods of imaging. The object of the study was to complement the "standards for eleven measurements pert...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-02-01 00:00:00
abstract：:This paper presents a case of a pregnant woman who was admitted to the obstetrics and gynecology department because of a new onset of uncontrolled diabetes in 27 weeks gestation. The maternal and fetal diabetic complications suggested a chronic character of the disease which must have been undiagnosed before pregnancy...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2011-08-01 00:00:00
abstract：OBJECTIVES:Kujawsko-pomorskie province is a region with high morbidity and death-rate from uterine cervix cancer. One of the methods of improve this situation is to perform prophylactic physical examinations to find the least advanced stages as possible. DESIGN:The aim of the study was to estimate the results of proph...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2005-09-01 00:00:00
abstract：OBJECTIVES:Overexpression of intracellular adhesion molecule-I (ICAM-1) was observed in many benign and malignant tumors. The aim of our study was to evaluate its serum concentrations as well as CA-125 in women with benign ovarian tumors. MATERIALS AND METHODS:Forty-five women treated surgically because of benign ovar...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2004-10-01 00:00:00
abstract：OBJECTIVES:Objective was to examine the relationship of obesity, body fat distribution fasting plasma insulin concentrations and triglycerides of pro-thrombotic and fibrinolitics factors in pre and postmenopausal women. MATERIAL AND METHODS:We assessed 24 (13 nonobese and 11 obese) postmenopausal and 44 (15 obese and ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
