Abstract：
AIM:To evaluate the a-chemokine stromal cell-derived factor-1 (SDF-1)/CXCL12 levels in the peritoneal fluid (PF) and plasma of patients with epithelial ovarian cancer (EOC, n=101), serous cyst (n=34) or normal controls (n=20). SDF-1alpha concentrations were correlated to myeloid (M) and lymphoid (L) dendritic cells (DC). MATERIAL AND METHODS:SDF-1alpha levels were analysed using a sensitive enzyme-linked immunosorbent assay (ELISA). DC were evaluated by flow cytometry. RESULTS:The SDF-1alpha concentrations in peritoneal fluid were elevated in the EOC patients in comparison to the patients with serous cyst (the reference group). The PF SDF-1alpha levels were significantly higher in FIGO III and IV patients than in FIGO stage I. There were no significant differences in the PF SDF-1alpha levels with respect to tumor grade or histology Additionally there were no significant differences in the plasma SDF-1alpha levels in EOC patients in comparison with the reference and control groups. The SDF-1alpha levels in the plasma of FIGO stage III patients were significantly higher than that of stage I. Patients with undifferentiated carcinoma had significantly higher plasma SDF-1alpha levels than patients with serous cystadenocarcinoma. No significant differences were noted in the plasma SDF-1alpha levels within different tumor grades. There was no significant correlation between PF and plasma SDF-1alpha levels and the percentage of myeloid and lymphoid DC in the PB and PF of EOC patients. CONCLUSION:SDF-1alpha production in EOC patients may depend on the clinical stage of the tumor. Increased levels of SDF-1alpha and lymphoid DC in the PF of EOC patients may play an important role in the pathogenesis of this disease.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Wertel I,Polak G,Tarkowski R,Kotarska Msubject
Has Abstractpub_date
2011-06-01 00:00:00pages
421-5issue
6eissn
0017-0011issn
2543-6767journal_volume
82pub_type
杂志文章abstract：OBJECTIVES:Environmental factors may play equally critical role as genes in facial embryogenesis. It was suggested that cleft palate occurring in association with cleft lip may result from environmental factors that affect development of both the lip and the palate. Cleft lip forms from the third through seventh week o...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-04-01 00:00:00
abstract：:It was found that amniotic fluid (38-42 Hbd) contains hydroxyproline in concentration about 10 micrograms/ml. Gel filtration and dialysis demonstrated that most of hydroxyproline exists in a form of low molecular weight products. Furthermore, it was found that amniotic fluid contains a protein which eluates during gel...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：:The paper contains a review of the literature on the correlation between Chlamydia trachomatis infection and CIN as well as invasive cervical cancer. This infection is not only responsible for inflammation (very often occult) in the upper genital tract and PID but also is probably one of the causes of cervical hypertr...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2002-05-01 00:00:00
abstract：:The course of actinomycetic infections in two females with IUD is presented. Both patients needed surgery. Literature review taking into a special consideration laboratory diagnosis has been performed. Infection caused by other than Actinomyces israelii species was observed. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-07-01 00:00:00
abstract：INTRODUCTION:Vascular-cellular adhesion molecule-1 (VCAM-1) overexpression on the cells' surface is stimulated by pro-inflammatory cytokines, bacterial endotoxins, reactive oxygen species and lipid peroxides. In the serum also the soluble form of VCAM-1 (sVCAM-1) is present. The beta 1-integrin family molecule VLA-4 (C...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-10-01 00:00:00
abstract：:The influence of hormone replacement therapy (HRT) on coagulation system has not been completely explained yet. We measured plasma activities of antithrombin III, protein C and protein S before and after 6 and 12 months of HRT in 48 postmenopausal women. HRT consisted of transdermal estradiol and orally medroxyprogest...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1996-08-01 00:00:00
abstract：OBJECTIVE:We aimed to demonstrate non-inferiority of delayed cord clamping (DCC) and cord milking (CM) in comparison to early cord clamping (ECC) in the incidence of hyperbilirubinemia requiring phototherapy. MATERIAL AND METHODS:467 of maternal-foetal dyads were screened for eligibility. 389 term infants, of breastfe...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2020.0096
更新日期：2020-01-01 00:00:00
abstract：DESIGN:The aim of our study was estimation of frequency of occurrence endometriosis at girls operated from different indications, research of predisposing factors and estimation of selected biophysical parameters. MATERIAL AND METHODS:Material determined 14 of patients in 13 to 21 years old of life operated on account...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-05-01 00:00:00
abstract：:We analysed the indications to myomectomy in females in reproductive age and estimated efficasy of this treatment. 112 patients aged 23-45 were analysed. Most common indication to this procedure were: menorrhagia--45.54%, myoma found at gynecological examination--21.43%, adnexal mass--20.54% and pelvic pain--15.18%. 5...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1997-09-01 00:00:00
abstract：OBJECTIVE:To assess the results of clomiphene citrate ovarian stimulation vs laparoscopic electrocoagulation of the ovaries in infertile women with PCOS. DESIGN:47 women with PCOS were included into the study. 25 of them had ovarian stimulation using clomiphene citrate (100 mg for 5 consecutive days, during 6 cycle) a...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：:The hysteroscopic evaluation of uterine openings in 23 sterile women was described. The attention was paid to morphological features of obliterated uterine openings. The hysteroscopic examination of structural changes located in uterine openings seems to be a reliable method for evaluation of potency of oviducts. This...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：:26 patients out of 48 (54%) with an advanced ovarian carcinoma (III and IV degree) treated in the first stage by means of Adriablastine, Cisplatin and Cyclophosphamide responded to the therapy. Complete remission was achieved in 24 patients (50%), and partial remission (PR) only in 2 patients. Four patients with CR in...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：1989-02-01 00:00:00
abstract：:Obesity-related metabolic and functional disorders may disturb adaptation process taking place in pregnant women body. Insufficient adaptation may lead to development of several medical complications during pregnancy, labor, delivery, and puerperium. Maternal obesity is associated with increased frequencies of hyperte...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：1999-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the outcomes of treatment in patients suffering from recurrent spontaneous abortion and antiphospholipid syndrome. MATERIALS AND METHODS:148 observed women suffering from recurrent abortion with presence of lupus anticoagulant antibodies (LA) and/or high moderate concentration of anticardiolipin ...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2003-10-01 00:00:00
abstract：AIM:The aim of this report is to present data concerning results and complications related to infertility treatment using assisted reproductive technology (ART) and insemination (IUI) in Poland in 2011. MATERIALS AND METHODS:The report was prepared by the Fertility and Sterility Special Interest Group of the Polish Gy...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1770
更新日期：2014-07-01 00:00:00
abstract：:Uterine septum is the major intrauterine disorder associated with infertility and recurrent abortions. The aim of the study was to find out what is the effectiveness of hysteroscopic intrauterine septum resection in terms of reproductive outcome and in comparison with conventional procedure. The mean follow up period ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-10-01 00:00:00
abstract：:During the past 15 years, the Wroclaw Medical Academy Institute of Obstetrics and Gynecology experimented on the construction of IUDs. The paper discusses the positive and negative points of those devices which were produced as compared with the Gravigard and the Copper T-200. There were 702 women observed for 7 yea...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1981-03-01 00:00:00
abstract：UNLABELLED:THE OBJECTIVES: The aim of this study was to evaluate the clinical value of blood flow indicies for differentiating between benign and malignant ovarian tumours. MATERIALS AND METHODS:Realisation of the aim was based on the analysis of examinations' results of 686 ovarian tumors. For each recorded blood flo...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-08-01 00:00:00
abstract：:Scientific journals are ranked and evaluated to measure their relative importance and influence on science within a specific field. One of the tools most widely used to evaluate and compare journals is the Thomson Reuters Impact Factor In Poland a specific value of a scientist's Impact Factor is required for academic ...
journal_title：Ginekologia polska
pub_type： 社论
doi：
更新日期：2011-08-01 00:00:00
abstract：OBJECTIVE:Predictive factors of damage to the Fallopian tube may guide the treatment for patients with tubal pregnancy. The purpose of this study was to evaluate the predictive value of ultrasonographic findings in patients affected by ampullary pregnancy for the determination of the depth of trophoblastic infiltration...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1893
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVES:G-CSF is a stimulatory factor of granulocyte colony formation. In vitro and in vivo G-CSF stimulates the proliferation of granulocyte precursors and enhances phagocytic functions of mature cells. Indirect evidence of this might be the increase of the activity of granulocyte enzymes participating in phagocyto...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2004-02-01 00:00:00
abstract：:Authors' analysis refers to reasons for which some women did not meet criteria for the programme of collection of cord blood by The Cord Blood Bank in Warsaw. The main reasons were: 1) reactivation of infection with CMV virus, 2) complications of delivery and 3) technical problems. We present also preliminary results ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：UNLABELLED:Preeclampsia is one of the most frequent and dangerous complications of a pregnancy. In preeclamptic pregnancies the spiral arteries are not modified properly. Disturbed blood flow finally leads to hypoxia which is responsible for the dysfunction of the endothelium. Endothelial growth factor (VEGF) and place...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2007-11-01 00:00:00
abstract：OBJECTIVES:The objective of this study was to determine the maternal PLAC1 protein levels in early and late onset preec-lampsia. MATERIAL AND METHODS:A total of 135 pregnant women were included in the study, of which 55 were at < 34 weeks of gesta-tion and 80 were at ≥ 34 weeks of gestation, between June and November ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2018.0025
更新日期：2018-01-01 00:00:00
abstract：:Carcinoma of the Bartholin gland is rate, comprising less then 1% of female genital tract neoplasms. We present the case of 52-year-old female with Bartholin gland carcinoma, discuss the therapeutic problems and review the data from the world literature. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-03-01 00:00:00
abstract：:Three different variants of biologically agressive cervical cancers, such as: basaloid carcinoma, glassy cell carcinoma and small cell endocrine carcinoma, have been reported. Hematoxylin and eosin, periodic acid-Schiff and immunohistochemical stains were used. The course of disease and aplication of treatment has bee...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2007-09-01 00:00:00
abstract：OBJECTIVES:The two functions of the lower urinary tract are the filling/storage and emptying. Similarly lower urinary tract symptoms can be subdivided. DESIGN:The aim of the study was the estimation of usefulness of present complaints-voiding history in diagnosis of lower urinary tract dysfunctions. MATERIAL AND METH...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：2001-03-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to assess the concordance between the preoperative endometrial sampling and microscopic examination of the hysterectomy specimens in patients surgically treated for atypical endometrial hyperplasia and endometrial carcinoma. MATERIAL AND METHODS:We analysed a group of 204 patients, ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2016.0031
更新日期：2016-01-01 00:00:00
abstract：INTRODUCTION:Ectopic pregnancy may lead to massive haemorrhage, infertility or death. Prompt diagnosis and treatment are crucial to save patients who would otherwise die. Serum amylase and lipase measurements are known biochemical markers of pancreatic inflammation and a recognized finding that may help diagnose acute ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2009-05-01 00:00:00
abstract：AIM:To assess the correlation between homocysteine concentrations and gestational age, gender Apgar score, complications in pregnancy delivery modalities and levels of vitamin B12 and foliate. MATERIAL AND METHODS:Concentration of homocysteine, vitamins-B12, foliate were measured in cord blood and mother blood. There ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2011-10-01 00:00:00
