[Effectiveness of 3-drug therapy in patients with advanced ovarian cancer].

Abstract:

:26 patients out of 48 (54%) with an advanced ovarian carcinoma (III and IV degree) treated in the first stage by means of Adriablastine, Cisplatin and Cyclophosphamide responded to the therapy. Complete remission was achieved in 24 patients (50%), and partial remission (PR) only in 2 patients. Four patients with CR in III degree agreed to another operation. These have lived 60, 40, 40 and 36 months after the surgery. The authors achieved significantly statistically better results of the therapy by means of the procedure presented in comparison with the effectiveness of two-drug chemotherapy without applying Cisplatin.

journal_name

Ginekol Pol

journal_title

Ginekologia polska

authors

Kwaśniewska-Rokicińska C,Kaleta B,Kumor-Głodny T

subject

Has Abstract

pub_date

1989-02-01 00:00:00

pages

86-9

issue

2

eissn

0017-0011

issn

2543-6767

journal_volume

60

pub_type

临床试验,杂志文章
  • [Levels of immunoreactive cytokines in serum of women with preeclampsia or severe pregnancy hypertension].

    abstract:OBJECTIVE:The purpose of the study was to compare concentrations of inflammatory and Th1/Th2 cytokines in serum obtained from women with preeclampsia or severe pregnancy hypertension versus normotensive controls. MATERIAL AND METHODS:The study group consisted of 34 pregnant women with hypertension over 140/90mmHg and ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Tarnowska-Madra U,Leibschang J,Kowalska B,Filipp E,Kozar A,Nimer A,Maciejewski T

    更新日期:2010-03-01 00:00:00

  • Comparison of the second-generation Beckman Coulter IVD and first-generation AnshLabs ELISA assays for anti-Müllerian hormone in patients undergoing IVF treatment.

    abstract:OBJECTIVES:Ovarian reserve is the main factor influencing the efficacy of infertility treatment. Currently the anti- Müllerian hormone is the main indicator of the ovarian reserve and has a wide spectrum of clinical importance. It achieved a high clinical value right after the introduction of the first commercial AMH a...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Lukaszuk K,Kuczynski W,Kunicki M,Ludwikowska B,Liss J,Malinowska I,Lukaszuk A,Bednarowska A,Kuczynska A,Kuc P,Pastuszek E

    更新日期:2014-10-01 00:00:00

  • [Maternal and umbilical bilirubin concentration at the time of delivery depending on course of pregnancy and labour].

    abstract:OBJECTIVES:Newborns hyperbilirubinemia is an interesting, complicated and controversial clinical problem. An elevated concentration of it can be connected with increased risk of jaundice. Also, maternal bilirubin can play a part in the development of jaundice in mature newborns. MATERIAL AND METHODS:The research inclu...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Suchońska B,Wielgoś M,Kociszewska-Najman B,Marianowski L

    更新日期:2003-08-01 00:00:00

  • [Age at menarche and the investigation of selected biophysical parameters in the course of menarche].

    abstract:DESIGN:The aim of our study was a currently clinical analysis of menarche. MATERIALS AND METHODS:The mean age of menarche was investigated in 4497 girls between 1975-1997 69 girls were examined throughly in the course of menarche. Age at menarche, body weight, height, body mass index (BMI), some of the hormones and ul...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Kurdzielewicz M,Rzepka-Górska I,Błogowska A,Kosmowska B

    更新日期:1999-05-01 00:00:00

  • [A simple method of isolation of human spermatozoa with the swim-up technique: usefulness of various chemically defined media, and influence of porcine follicular fluid].

    abstract::The aim of the study was to define minimal conditions necessary to isolate human spermatozoa using their swim-up potential. The efficiency of the isolation of spermatozoa from seminal fluid was tested after 1 hour incubation at 37 degrees C of seminal plasma together with isolation mediums, at the volume proportion 2:...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Barczyk A,Kula K

    更新日期:2002-07-01 00:00:00

  • [Vaginal and cervical bacterial colonization in patients with threatening preterm labor].

    abstract:OBJECTIVES:The aim of the following work was to evaluate vaginal and cervical colonization in patients with threatening preterm labor and comparing the frequency of colonization of the term and preterm labor groups. MATERIAL AND METHODS:532 pregnant women with threatening preterm labor were included into the clinical ...

    journal_title:Ginekologia polska

    pub_type: 临床试验,杂志文章

    doi:

    authors: Czajka R,Rzepka R,Kwiatkowski S,Torbe A,Swiszczowska A,Mikołajek-Bedner W,Chłapowska E,Łodziato-Kheder M,Sokołowska M,Jaroszewicz A,Marcinkiewicz O,Zapałowska M

    更新日期:2010-11-01 00:00:00

  • Ruptured ectopic pregnancy mimicking acute pancreatitis.

    abstract:INTRODUCTION:Ectopic pregnancy may lead to massive haemorrhage, infertility or death. Prompt diagnosis and treatment are crucial to save patients who would otherwise die. Serum amylase and lipase measurements are known biochemical markers of pancreatic inflammation and a recognized finding that may help diagnose acute ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Mitura K,Romanczuk M

    更新日期:2009-05-01 00:00:00

  • [Respiratory distress in newborns born to hypertensive mothers and acid-base equilibrium and the ion composition of the amniotic fluid].

    abstract::Twenty-five samples of amniotic fluid obtained by amniocentesis from 25 pregnant women with hypertension in the 35 to 40 weeks of pregnancy were studied. The following biochemical determinations were done in the samples: acid-base equilibrium (pH, pO2, pCO2, base deficit, standard HCO3- and total CO2), concentrations ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Wojcicka-Jagodzińska J,Kuczyńska-Sicińska J,Romejko E,Smolarczyk R,Szczecina R

    更新日期:1989-10-01 00:00:00

  • Polymorphisms of collagen 1A1 (COL1A1) gene and their relation to bone mineral density in postmenopausal women.

    abstract:OBJECTIVES:The goal of this study was to evaluate the frequency of Sp1 +1245G>T (rs 1800012) and -199 7G>T (rs 1107946) COL1A1 gene polymorphisms in postmenopausal women with osteoporosis and osteopenia as well as assessing their relations with the clinical parameters and parameters of bone turnover. STUDY DESIGN:The ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.17772/gp/60550

    authors: Majchrzycki M,Bartkowiak-Wieczorek J,Wolski H,Drews K,Bogacz A,Czerny B,Zagrodnik-Ułan E,Seremak-Mrozikiewicz A

    更新日期:2015-12-01 00:00:00

  • Cervical intraepithelial neoplasia--biopsy methods as AIDS for diagnosis and therapy.

    abstract::Between 1977 and 1995, a total of 1610 patients were admitted to hospital with Pap III, IIID, IVa or IVb. The results of 1182 conisations with cervical abrasion and 428 ectocervical surface scrapings with cervical abrasion were evaluated. The percentage of findings of (CIN II was 35.2% for all cases and 23.3% for coni...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Quaas J,Budner M,Heinrich J

    更新日期:2000-03-01 00:00:00

  • Premature fetal tissues are possible source of valuable mesenchymal stem cells.

    abstract:OBJECTIVES:Comparison of the ability to inhibit alloactivated lymphocytes proliferation of human Wharton Jelly (WJ) and amniotic membrane (AM) mesenchymal stem cells (MSCs) from preterm and term pregnancies. MATERIAL AND METHODS:Term-WJ-MSCs (n = 5) and Preterm-WJ-MSCs (n = 1) were obtained from tissue explants by adh...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.5603/GP.a2017.0037

    authors: Dąbrowski FA,Burdzinska A,Kulesza A,Kaleta B,Pączek L,Wielgoś M

    更新日期:2017-01-01 00:00:00

  • [The significance of -174G/C polymorphism of the gene coding for interleukin-6 in neonatal infections].

    abstract:OBJECTIVE:Interleukin-6 (IL-6) is a specific marker of early onset infections in the newborns. In recent years it has been suggested that in regulations of IL-6 activity could play a role the genetic polymorphism (-174G/C) in the promoter region of the gene coding for IL-6. The aim of our study was to analyse the frequ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Wojsyk-Banaszak I,Seremak-Mrozikiewicz A,Szczapa J,Drews K,Zandecka-Dziubak J,Mrozikiewicz PM

    更新日期:2005-02-01 00:00:00

  • [A case of cervix neck pregnancy--report on conservative treatment].

    abstract::Authors presented successful conservative treatment early diagnosed cervical pregnancy. After this procedure abdominal hysterectomy was not necessary. ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Rokita W,Szymkiewicz-Malarewicz J,Wydrzyński G,Malarewicz A

    更新日期:1996-06-01 00:00:00

  • [Effect of past abortions and the sequence of gestations on the course of the next pregnancy and labor as well as the state-at-delivery, maturity, dystrophia and mortality rate of the newborn infants].

    abstract::Legal abortions have reduced the number of miscarriages by 20%, and of abandoned children by 56%; but at the same time, can be hazardous to the mother both initially (loss of blood, punctured uterus, damaged cervix) and later (infections in the reproductive system, infertility, extrauterine pregnancy, psychological di...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Osuch-Jaczewska R,Tomala J

    更新日期:1979-02-01 00:00:00

  • [Personal observations on the efficacity and tolerance of Spiran W intrauterine device of Polish production].

    abstract::Basic methods of contraception of unwanted pregnancy are reviewed: mechanical, vaginal devices, hormonal tablets, and IUDs. On the basis of personal experience the author considers that, compared with other methods of contraception, the intrauterine spiral is the safest device for the female organism. An evaluation...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Goszcz J

    更新日期:1975-03-01 00:00:00

  • [Evaluation of the generation of interleukin-10 by peripheral blood lymphocytes in women with endometriosis].

    abstract::The aim of study was the evaluation of generating the IL-10 by peripheral blood lymphocytes in women with endometriosis according to the stage of of the disease. Cytokine was estimated by immunoenzymatic method Elisa. The generation of IL-10 by peripheral blood lymphocytes was lower in patients with all stages of endo...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Szyłło K,Lewy J,Tchórzewski H,Głowacka E,Banasik M,Lewkowicz P,Kamer-Bartosińska A

    更新日期:2001-05-01 00:00:00

  • Subcutaneous rifampicin versus povidone-iodine for the prevention of incisional surgical site infections following gynecologic oncology surgery - a prospective, randomized, controlled trial.

    abstract:OBJECTIVES:Surgical site infection (SSI) following gynecologic oncology surgery is a severe problem for both patient and surgeon in terms of increasing morbidity, length of hospital stay, anxiety, and costs. In this prospective, randomized, controlled study we investigated the effect of subcutaneous rifampicin and povi...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.5603/GP.a2020.0134

    authors: Kömürcü Karuserci Ö,Balat Ö

    更新日期:2020-01-01 00:00:00

  • [Stromal leydig cell tumor coexisting with ascites].

    abstract::The stromal Leydig cell tumour (SLCT), a very rare, benign neoplasm was described in 75-year old woman. The patient presented the typical signs of virilisation (hirsutism, masculine alopecia, moderate clitoris enlargement, deep voice) as well as hypertension and insulin independent type of diabetes mellitus (IIDM). Ad...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Czupkałło G,Jakowicki JA,Baranowski W

    更新日期:2001-10-01 00:00:00

  • [Agresive variants of uterine cervical cancers].

    abstract::Three different variants of biologically agressive cervical cancers, such as: basaloid carcinoma, glassy cell carcinoma and small cell endocrine carcinoma, have been reported. Hematoxylin and eosin, periodic acid-Schiff and immunohistochemical stains were used. The course of disease and aplication of treatment has bee...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Kedzia W,Bierła J,Kedzia H

    更新日期:2007-09-01 00:00:00

  • [Acute complete uterine inversion--care report].

    abstract:OBJECTIVES:Acute puerperal uterine inversion is a rare but very feared obstetrical complication. It determines an almost immediate shock and serious metrorrhagia. It is a introflexion of parietes uteri which takes place during the third stage of labor or during the first hours of puerperium. It can be distinguished in ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Studziński Z,Branicka D

    更新日期:2001-11-01 00:00:00

  • An observational study of the risk of neonatal macrosomia, and early gestational diabetes associated with selected candidate genes for type 2 diabetes mellitus polymorphisms in women with gestational diabetes mellitus.

    abstract:OBJECTIVES:1) to analyse the prevalence of selected candidate genes for type 2 diabetes mellitus polymorphisms (IRS1 G972R; ENPP1 K121Q; ADRB3 W64R) among women with gestational diabetes; and 2) to investigate any association between variants of these genes and risk of neonatal macrosomia. MATERIAL AND METHODS:We cond...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.5603/GP.a2018.0119

    authors: Zawiejska A,Wender-Ozegowska E,Bogacz A,Iciek R,Mikolajczak P,Brazert J

    更新日期:2018-01-01 00:00:00

  • [The role of gonadotropins, cyclic AMP, 22-R-OH-cholesterol and cofactors in regulating endocrine functions of the Leydig cells in rats. III. Mechanisms responsible for "desensitization" of the Leydig cells of rats caused by high doses of hCG].

    abstract::Two groups of rats (a control group and the group examined) were administered intraperitoneally supraphysiological doses of hCG in order to induce a "down regulation" effect on the level of receptors LH and to achieve the desensibilization of Leydig cells. The authors tried to find out at which stage of sequence of ch...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Grochowski D,Szamatowicz M

    更新日期:1989-05-01 00:00:00

  • [Cholesterol and its fractions in women after ovariectomy treated with estraderm TTS].

    abstract::25 ovariectomized women mean age 47 +/- 5 years were treated with transdermal 17 beta Estradiol in the shape of Estraderm TTS 100 plasters. Drugs were administrated in 28 days cycles during 24 weeks. Chlormadinon in daily dose 2 mg was added from 16 to 28th day of the fourth therapeutic cycle. Total cholesterol, trigl...

    journal_title:Ginekologia polska

    pub_type: 临床试验,杂志文章

    doi:

    authors: Matuszewski W,Wieczorek J

    更新日期:1996-04-01 00:00:00

  • [SARS-CoV infection and pregnancy].

    abstract::SARS is a highly contagious infection, caused by new coronavirus SARS-CoV. Immunopathological mechanisms responsible for the reaction to SARS-CoV infection have not yet been fully elucidated. Cytokine profile of SARS patients showed marked elevation of Th1 cytokine, interferon gamma, inflammatory cytokines for at leas...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Ksiezakowska K,Laszczyk M,Wilczyński J,Nowakowska D

    更新日期:2008-01-01 00:00:00

  • Increased oxidative stress is associated with insulin resistance and infertility in polycystic ovary syndrome.

    abstract:OBJECTIVES:The present study aims to investigate the role of oxidant-antioxidant status in young women with polycystic ovary syndrome (PCOS). MATERIAL AND METHODS:Seventy-one women with PCOS and 53 healthy controls are compared in aspect of demographic characteristics, biochemical data, hormones, and oxidant-antioxida...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.5603/GP.2016.0079

    authors: Özer A,Bakacak M,Kıran H,Ercan Ö,Köstü B,Kanat-Pektaş M,Kılınç M,Aslan F

    更新日期:2016-01-01 00:00:00

  • [The respiratory system in pregnancy].

    abstract::A survey throughout world literary output concerning physiology of respiratory system in pregnancy was made in this work. Metabolical changes caused by the increase of progesterone and other substances concentration and changes of the mechanics of ventilation connected by diaphragm raising caused by the growing uterus...

    journal_title:Ginekologia polska

    pub_type: 杂志文章,评审

    doi:

    authors: Buchacz P,Poreba R,Kozielski J

    更新日期:1995-06-01 00:00:00

  • Chronic and gestational metabolic disorders have a different impact on late-pregnancy endothelial function in pregnant women.

    abstract:OBJECTIVES:We investigated how maternal endothelial function is affected by pregestational (Type 1) diabetes mellitus (PGDM) or gestational diabetes mellitus (GDM) and/or chronic hypertension (chHT) or gestational hypertension (PIH). METHODS:We conducted a prospective, observational study involving 78 participants wit...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:10.17772/gp/62209

    authors: Zawiejska A,Wender-Ożegowska E,Brazert J

    更新日期:2016-01-01 00:00:00

  • [Life threatening conditions in premature infants].

    abstract:UNLABELLED:The aim of the study was to analyze life-threatening conditions of the premature neonates who required hospitalization in The Neonatal Intensive Care Unit (NICU). Postnatal mortality was also taken into consideration. MATERIAL AND METHODS:The study group consisted of the neonates born prematurely in the Obs...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Kociszewska-Najman B,Borek-Dziecioł B,Kulikowska-Matłosz J

    更新日期:2003-10-01 00:00:00

  • [Effect of immunotherapy on the level of immunoglobulin in serum of women with pruritus of the vulva].

    abstract::This study was performed in 52 women in their early postmenopausal period, divided into two equal groups. The control group included women with menopausal symptoms only, women in the study group demonstrated also pruritus. All women were on estrogen replacement therapy, additionally a bacterial auto-vaccine was admini...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Stanosz S,Sycz G,Borowiak M

    更新日期:1992-01-01 00:00:00

  • [Primary Bartholin gland carcinoma].

    abstract::Carcinoma of the Bartholin gland is rate, comprising less then 1% of female genital tract neoplasms. We present the case of 52-year-old female with Bartholin gland carcinoma, discuss the therapeutic problems and review the data from the world literature. ...

    journal_title:Ginekologia polska

    pub_type: 杂志文章

    doi:

    authors: Klasa-Mazurkiewicz D,Emerich J,Milczek T,Ciach K

    更新日期:2003-03-01 00:00:00