Abstract:
OBJECTIVES:The present study aims to investigate the role of oxidant-antioxidant status in young women with polycystic ovary syndrome (PCOS). MATERIAL AND METHODS:Seventy-one women with PCOS and 53 healthy controls are compared in aspect of demographic characteristics, biochemical data, hormones, and oxidant-antioxidant status. RESULTS:The PCOS group had significantly lower zinc, higher malondialdehyde and gluthathione peroxidase and lower serum catalase levels than the control group (p = 0.016, p < 0.001, p = 0.043 and p = 0.025 respectively). The PCOS patients with IR had significantly higher malondialdehyde, lower catalase and serum zinc levels than the PCOS patients without IR (p = 0.015, p = 0.010, p = 0.001 respectively). The infertile PCOS patients had significantly higher malondialdehyde, lower catalase and serum zinc levels than the fertile PCOS patients (p = 0.022, p = 0.045,p = 0.001 respectively). There was a statistically significant and positive correlation between HOMA-IR and malondialdehyde values (r = 0.523, p = 0.001), between HOMA-IR and glutathione peroxidase values (r = 0.468, p = 0.001) and between HOMA-IR and zinc values (r = 0.601, p = 0.001). There was a statistically significant and negative correlation between HOMA-IR and catalase values (r = -0.493, p = 0.001). CONCLUSIONS:The patients with PCOS are under oxidative stress and this oxidative stress seems to be the highest in patients with IR and with infertility. Despite the prominent increase in the oxidative stress, there was a variation in the antioxidant response.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Özer A,Bakacak M,Kıran H,Ercan Ö,Köstü B,Kanat-Pektaş M,Kılınç M,Aslan Fdoi
10.5603/GP.2016.0079subject
Has Abstractpub_date
2016-01-01 00:00:00pages
733-738issue
11eissn
0017-0011issn
2543-6767pii
VM/OJS/J/48440journal_volume
87pub_type
杂志文章abstract::The efficiency of glycemia control was compared in two groups of insulin dependent diabetic pregnancies treated with insulin, with and without the aid of the Camit-Diacomp system. The efficiency of glycemia control was analysed in all three trimesters of pregnancy. Mean diurnal fluctuations of glycemia levels in both ...
journal_title:Ginekologia polska
pub_type: 临床试验,杂志文章
doi:
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abstract:OBJECTIVES:The aim of this study is to assess the choroidal thickness (CT) with use of EDI-OCT in patients before and after delivery depending on the mode of delivery. MATERIAL AND METHODS:The study involved 146 eyes of 73 patients aged 20-34 years, after natural labour (66 eyes) and C-section (80 eyes). Main inclusio...
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journal_title:Ginekologia polska
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journal_title:Ginekologia polska
pub_type: 杂志文章,评审
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journal_title:Ginekologia polska
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doi:
更新日期:2000-04-01 00:00:00
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journal_title:Ginekologia polska
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更新日期:2001-04-01 00:00:00
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journal_title:Ginekologia polska
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更新日期:2001-05-01 00:00:00
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journal_title:Ginekologia polska
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journal_title:Ginekologia polska
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journal_title:Ginekologia polska
pub_type: 杂志文章
doi:
更新日期:2010-08-01 00:00:00
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journal_title:Ginekologia polska
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doi:
更新日期:2001-12-01 00:00:00
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doi:
更新日期:2011-06-01 00:00:00
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journal_title:Ginekologia polska
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doi:
更新日期:1995-05-01 00:00:00
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doi:
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doi:
更新日期:2005-08-01 00:00:00
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