Abstract：
OBJECTIVES:Gestational diabetes mellitus is a carbohydrate intolerance that occurs during pregnancy. Various inflammatory mediators are considered to be risk factors leading to GDM development. Among them are pro-inflammatory cytokines, such as IL16 and IL18. The aim of this study was to examine the association between IL16 and IL18 polymorphisms and GDM. MATERIAL AND METHODS:This study included 204 pregnant women with GDM and 207 pregnant women with normal glucose tolerance (NGT). All samples were genotyped in duplicate using allelic discrimination assays with TaqMan® probes. RESULTS:We observed that there was a decreased frequency of IL16 rs4778889 CC genotype carriers among women with GDM (CC vs. CT + TT: OR = 0.14; 95% CI = 0.02-1.15; p = 0.034). However, there was no significant difference in the distri-bution of alleles (C vs. T: OR = 0.81; 95% CI = 0.54-1.21; p = 0.30). There was a decreased frequency of the IL18 rs187238 G allele among GDM women (G vs. C: OR = 0.71; 95% CI = 0.53-0.96; p = 0.027). We also observed a decreased frequency of the IL18 rs1946518 T allele among women with GDM; however, this difference had only borderline statistical significance. We observed an association between IL18 rs187238, rs1946518 and BMI in pregnant women. CONCLUSIONS:The results of this study suggest that IL18 rs187238 and rs1946518 polymorphisms may be associated with an increased risk of GDM as well as with BMI in pregnant women.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Tarnowski M,Wieczorek A,Dziedziejko V,Safranow K,Ustianowski P,Celewicz Z,Pawlik Adoi
10.5603/GP.a2017.0047subject
Has Abstractpub_date
2017-01-01 00:00:00pages
249-254issue
5eissn
0017-0011issn
2543-6767pii
VM/OJS/J/50530journal_volume
88pub_type
杂志文章abstract：OBJECTIVES:The aim of our study was to determine the risk of aneuploidy and associated malformations in fetuses with holoprosencephaly. We have also analyzed the gestational age during the first examination. DESIGN:We have studied ultrasound reports of fetuses with holoprosencephaly. MATERIALS AND METHODS:We analyzed...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2007-06-01 00:00:00
abstract：OBJECTIVES:G-CSF is a stimulatory factor of granulocyte colony formation. In vitro and in vivo G-CSF stimulates the proliferation of granulocyte precursors and enhances phagocytic functions of mature cells. Indirect evidence of this might be the increase of the activity of granulocyte enzymes participating in phagocyto...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2004-02-01 00:00:00
abstract：:Maldevelopment of the müllerian ducts occurs in a variety of forms, and each anomaly is distinctive. Nevertheless, some generalizations can be made. A comprehensive preoperative evaluation of patients with suspected uterovaginal malformations is essential, but a clear understanding of the particular anomaly may not be...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2005-11-01 00:00:00
abstract：OBJECTIVES:The aim of our study was clinical analysis of patients operated with squamous cell carcinoma of the uterine cervix. MATERIALS AND METHODS:Between 1972 and 1991 at the 2nd Department of Obstetrics and Gynecology Medical University of Gdańsk 687 total hysterectomies in Wertheim-Meigs method were performed in ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1999-02-01 00:00:00
abstract：:The questionnaire included 220 men from childless married couples who referred to the Department of Reproduction and Andrology of the Medical Academy in Lublin for 4 months in 1992. The treatment period of childlessness in those couples ranged from several months to 17 years. The authors tried to establish if, and to ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:The paper presents the course of treatment and results of pathological changes in the uterine cervix in 41 patients who underwent cryotherapy by means of a cryotherapeutic apparatus UK-32, using liquid nitrogen as cryogenic fluid. Complete recovery in the form of typical stratified squamous epithelium was achieved in ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：:The HELLP syndrome is a variant of severe preeclampsia. Its leading symptoms are: hemolysis, increased liver enzymes and low platelet count. The treatment of the HELLP syndrome remains controversial as there are no standards of proven efficacy. The article presents a case of a 27- year-old patient, G1P0, 30 wk of gest...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2007-03-01 00:00:00
abstract：OBJECTIVE:Angiogenesis in malignant tumors is a prognostic factor associated with tumor growth and metastasis. The aim of the research was: determination of the angiodensity rate in two immunohistochemical techniques, estimation of the value of the examined parameter at different stages of clinical progression and hist...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：AIM OF STUDY:To define a relationship between emergency and elective indications for cesarean section and quantitative changes of percentage and quantity of T and B lymphocytes and their subpopulations in healthy full-term neonates. MATERIAL AND METHODS:The study included 43 healthy neonates born in the years 1998 - 2...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2009-10-01 00:00:00
abstract：UNLABELLED:The aim of the study was to analyze life-threatening conditions of the premature neonates who required hospitalization in The Neonatal Intensive Care Unit (NICU). Postnatal mortality was also taken into consideration. MATERIAL AND METHODS:The study group consisted of the neonates born prematurely in the Obs...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-10-01 00:00:00
abstract：UNLABELLED:Infertility has been recognized by WHO a disease concerning males and females. It is a serious social problem, therefore the evaluation of its reasons, its prevention and treatment is a subject of clinical studies. OBJECTIVE:To define the reasons of infertility and factors affecting fertility. MATERIAL AND...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2005-12-01 00:00:00
abstract：OBJECTIVES:Literature describing complications after colposuspension and analyses of the learning curve is scarce. Knowledge concerning this topic may lower the frequency of complications, improve the effectiveness of the procedure and increase patients' satisfaction. DESIGN:The purpose of the study was to evaluate ty...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2007-04-01 00:00:00
abstract：:Authors presented successful conservative treatment early diagnosed cervical pregnancy. After this procedure abdominal hysterectomy was not necessary. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1996-06-01 00:00:00
abstract：OBJECTIVES:Abdominal obesity is a risk factor for endometrial cancer. The negative impact of individual parameters of obesity on the procedural effects of endometrial cancer surgical treatment has been suggested. The aim of the current study was to estimate the relationship of particular parameters of obesity and in-ho...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2019.0095
更新日期：2019-01-01 00:00:00
abstract：:Among micro-organisms infecting vagina whose dominant genus is GV anaerobic bacteria are often present. There are reports that GV infections of vagina and uterine cervix, apart from their well-known negative role in obstetrics practice can play a role in carcinogenic processes of uterine cervix. The aim of the study w...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1997-10-01 00:00:00
abstract：OBJECTIVES:The purpose of the study was to check the conformity of diagnosis based on macroscopic hysteroscopy image with the respective pathology report. MATERIALS AND METHODS:Study population consisted of 160 patients aged 45-86 years, with abnormal uterine bleeding or abnormal ultrasonographic image of endometrium....
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：:Twenty-five samples of amniotic fluid obtained by amniocentesis from 25 pregnant women with hypertension in the 35 to 40 weeks of pregnancy were studied. The following biochemical determinations were done in the samples: acid-base equilibrium (pH, pO2, pCO2, base deficit, standard HCO3- and total CO2), concentrations ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1989-10-01 00:00:00
abstract：:Worldwide screening for early detection of ovarian cancer in both, the general population and the group of women at high risk for ovarian cancer including BRCA genes mutations carriers, has proven to be ineffective. The recommended screening methods, including a pelvic examination, transvaginal ultrasound, and CA125 p...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：10.17772/gp/1735
更新日期：2014-05-01 00:00:00
abstract：:During the past 15 years, the Wroclaw Medical Academy Institute of Obstetrics and Gynecology experimented on the construction of IUDs. The paper discusses the positive and negative points of those devices which were produced as compared with the Gravigard and the Copper T-200. There were 702 women observed for 7 yea...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1981-03-01 00:00:00
abstract：:The role of the peritoneal fluid in the physiology of reproduction, as well as in the transportation and survival of gametes, is little recognized. Taking this into consideration, the authors have examined the occurrence of spermatozoa in the peritoneal fluid, collected from patients during diagnostic laparoscopies, f...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：INTRODUCTION:Psychological factors are believed to play an important role in infertility and its treatment Psychological problems may be considered to be risk factors and the cause of reduced infertility, as well as contribute to an unsuccessful outcome of infertility treatment. OBJECTIVES:The aim of the study was to ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2008-02-01 00:00:00
abstract：:New diagnostic techniques employed in laboratories all over the world enable to create new tests for prenatal genetic diagnosis. They include cytogenetics, molecular-cytogenetics and molecular methods. Chromosomal numerical aberrations (aneuploidies) remain to be the most frequent genetic changes diagnosed prenatally ...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2013-10-01 00:00:00
abstract：:Concentration of thyroxine triiodothyronine and reverse-triiodothyronine in serum blood of 30 pregnant women were estimated, like a longitudinal study from 5 to 41 week of pregnancy. Significant increase of concentration of all hormones was observed. We presented also estimation of iodothyronines in blood serum in lab...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1994-06-01 00:00:00
abstract：AIM OF THE PAPER:Comparison of conventional cytodiagnostics with molecular identification of DNA and mRNA HPV HR, immunocytochemical test for suppressor protein P16 and nuclear Ki 67 to detect cervical pathology screening of the division to LG SIL and HG SIL. MATERIAL:630 Pap smears were taken from women with suspecte...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2012-12-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to assess the concordance between the preoperative endometrial sampling and microscopic examination of the hysterectomy specimens in patients surgically treated for atypical endometrial hyperplasia and endometrial carcinoma. MATERIAL AND METHODS:We analysed a group of 204 patients, ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2016.0031
更新日期：2016-01-01 00:00:00
abstract：:39 normal fetal heart examinations were evaluated since 20 week of gestation to term, and Doppler blood flow was analysed for mitral and tricuspid valves. The measurements were done always in good 4 chamber view and qualitative and quantitative analysis were performed, in terms of describing E and A waves and maximal ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1993-03-01 00:00:00
abstract：:Renal cell carcinoma accounts for 75% of renal neoplasms. Clear cell carcinoma is diagnosed in about 80% of the cases. Renal cell carcinoma most frequently metastasizes to the lungs (50-60%), lymph nodes (36%), bones (30-40%), liver (30-40%), and brain (5%). In other organs the metastasis changes are observed very rar...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1620
更新日期：2013-07-01 00:00:00
abstract：UNLABELLED:In our study the management and outcomes in 211 women with premature rupture of the membranes at term was analyzed. According to the time elapsed since PROM to delivery the study group was divided into four groups: within 6 h, within 6-12 h, within 12-24 h and over 24 h after PROM. The analysis was focused o...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-10-01 00:00:00
abstract：:Transvaginal ultrasound scanning was performed on 59 years old women with postmenopausal bleeding in anamnesis. Endometrial thickness was measured at its maximum in both longitudinal and transverse sections of the uterus. Also the thickness of uterus walls and ovaries in 3 planes were measured. Endometrium was irregul...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：:This case report describes a 40-year-old woman, primigravida. On 13,3 weeks of gestation we diagnosed an abnormal flow pattern in the umbilical artery and abnormal hyperechogenic structure in fetal abdomen. In next sonographic examination on 16 weeks of gestation we diagnosed ventriculomegaly and ahydramnion. We also ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-05-01 00:00:00
