Abstract：
:Worldwide screening for early detection of ovarian cancer in both, the general population and the group of women at high risk for ovarian cancer including BRCA genes mutations carriers, has proven to be ineffective. The recommended screening methods, including a pelvic examination, transvaginal ultrasound, and CA125 performed biannually continue to fail due to their relatively low sensitivity specificity and positive predictive value tests, as well as the fact that cancer is still detected in advanced stages (FIGO III/IV). However proteomic techniques and the ongoing search for more sensitive and specific biomarkers to increase effectiveness of screening tests for ovarian cancer bring new hope. We reviewed the current literature on screening for ovarian cancer in BRCA genes mutations carriers.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Synowiec A,Wcisło G,Bodnar L,Gasowska-Bodnar A,Szczylik Cdoi
10.17772/gp/1735subject
Has Abstractpub_date
2014-05-01 00:00:00pages
377-81issue
5eissn
0017-0011issn
2543-6767journal_volume
85pub_type
杂志文章,评审abstract：:Matrix metalloproteinases are proteolytic enzymes which degrade extracellular matrix proteins. Along with their specific inhibitors--issue inhibitors of metalloproteinases--they play an important role in the spreading of malignant tumours. The research conducted in recent years has shown that metalloproteinases and th...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2009-01-01 00:00:00
abstract：:The authors describe diagnostic difficulties connected with proper estimation of stromal sarcoma biological activities, which developed in uterus corpus in 18 year old girl previously treated with hormones, because of irregular painful menses. Macroscopic and microscopic investigations of postoperative specimen allowe...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：:A review of the literature for searching of biochemical marker of endometriosis is presented. The investigations with CA 125, antiendometrial antibodies, placental protein 14 and others have not established a sensitive screening test for predicting endometriosis, especially in early stages of the disease. Most authors...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：1999-03-01 00:00:00
abstract：:Diabetic pregnancy cause a lot of complications where fetal malformation is one of the most serious. Cardiac defects are besides the neural tube ones the most often in this group of pathology. Lack of pregnancy planning and thanks to it hyperglycemia during conceptive period and early embryogenesis increases the risk ...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2005-10-01 00:00:00
abstract：:Five cases of the cervical cancer in stage II b coexisting with pregnancy were presented. All patients were treated by radical radiotherapy consisting of external beam irradiation and brachytherapy. The spontaneous abortion or premature labor occurred during radiation after the dose 30.6-32 Gy of irradiation was deliv...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2002-01-01 00:00:00
abstract：OBJECTIVE:To assess the results of clomiphene citrate ovarian stimulation vs laparoscopic electrocoagulation of the ovaries in infertile women with PCOS. DESIGN:47 women with PCOS were included into the study. 25 of them had ovarian stimulation using clomiphene citrate (100 mg for 5 consecutive days, during 6 cycle) a...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
abstract：OBJECTIVE:Predictive factors of damage to the Fallopian tube may guide the treatment for patients with tubal pregnancy. The purpose of this study was to evaluate the predictive value of ultrasonographic findings in patients affected by ampullary pregnancy for the determination of the depth of trophoblastic infiltration...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1893
更新日期：2015-01-01 00:00:00
abstract：:In the group of 213 women with diagnosed endometriosis, after the histological analysis of the samples obtained during surgical procedure the following factors have been determined: the character and frequency of complaints, prevalence of the disease depending on the age of patients, it's localisation, coexistence wit...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1994-11-01 00:00:00
abstract：OBJECTIVES:The aims of the study were as follows: 1) to determine the applicability of vacuum-assisted core needle biopsy in the diagnosis and management of intraductal papillomas of the breast; 2) to define factors which increase the risk for underestimation of breast cancer. MATERIAL AND METHODS:Between 2002-2017, a...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2019.0022
更新日期：2019-01-01 00:00:00
abstract：MATERIAL AND METHODS:It was a retrospective analysis of fetal echocardiography results (analysis of congenital heart defect (CHD) and functional abnormalities in normal heart anatomy) in 83 fetuses diagnosed and treated in the same institution. RESULTS:In our group of fetuses, the most common structural defect, in add...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVE:To analyse deliveries after a previous cesarean section. STUDY DESIGN:The way of birth of 262 patients between 1993-1995 in the Ist Department of Obstetrics and Gynaecology of Warsaw University Hospital was analysed. Material was divided into two groups: an elective cesarean section operation was performed o...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：:Prognostic value of some clinical factors on the course of subsequent pregnancy in 117 women with unexplained recurrent spontaneous abortion undergoing immunization with paternal lymphocytes were evaluated in the study. The results allow to conclude that high efficiency of alloimmunization in preventing consecutive ab...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：1997-04-01 00:00:00
abstract：:Between 1994-1999 at the Department for Diagnosis of Congenital Malformations at the PPMH Institute there were ultrasound and echocardiography examinations performed in 40 fetuses with Down Syndrome. In our study most of the cases come from low risk groups of pregnant women. Congenital heart defects (AV-canal in 13/18...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2002-03-01 00:00:00
abstract：:This case report describes a 40-year-old woman, primigravida. On 13,3 weeks of gestation we diagnosed an abnormal flow pattern in the umbilical artery and abnormal hyperechogenic structure in fetal abdomen. In next sonographic examination on 16 weeks of gestation we diagnosed ventriculomegaly and ahydramnion. We also ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-05-01 00:00:00
abstract：OBJECTIVES:There are some data concerning homocysteine influence on fertilization and early embryogenesis, especially in women experiencing recurrent pregnancy loss (RSA). However, limited data support hypothesis that the ovum might be exposed to high homocysteine concentration what may be important in egg-sperm intera...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：:9.98% of all gynecological surgical interventions made at the Clinic in Zabrez from 1965 to 1971 were for ectopic pregnancy. 157 cases of ectopic pregnancy were chosen at random for clinical analysis. Microscopic examinations of the excised oviduct were made in order to establish the cause of tubular implantation. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1975-06-01 00:00:00
abstract：BACKGROUND:HLHS (hypoplastic left heart syndrome) is a serious congenital heart defect. In neonates with congenital heart disease HLHS accounts for nearly 25% of neonatal deaths. The etiology of HLHS is unknown. At present we expect to have those cases diagnosed in the second trimester of pregnancy. AIM:The main aim w...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2008-06-01 00:00:00
abstract：:The Impact Factor is a measure of average citation frequency for articles in a specific scientific journal during a specific period of time. IF takes into account the content, sources, layout and frequency and regularity of publishing. In order to get an impact factor, a journal needs to be first put on the Philadelph...
journal_title：Ginekologia polska
pub_type： 社论
doi：
更新日期：2010-10-01 00:00:00
abstract：OBJECTIVES:Pregnancy induced hypertension is believed to be a state of neutrophil overactivity, however all previous studies were done on isolated cells. DESIGN:To study neutrophil activity in whole blood of PIH women. MATERIALS AND METHODS:Neutrophil activity was estimated without isolation, in peripheral whole bloo...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：OBJECTIVES:To assess clinical efficacy of Total Prolift System surgery kit in the treatment of post hysterectomy vaginal vault prolapse. MATERIAL AND METHODS:Study group consisted of 27 women (mean age 60.3 +/- 10.3 years) who between February 2006 and September 2007 underwent vaginal cuff prolapse surgery with Total ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2008-12-01 00:00:00
abstract：OBJECTIVES:Paternal lymphocytes immunization has been proposed for several years as an efficient treatment for unexplained Recurrent Spontaneous Abortion (RSA), however precise mechanism that underline the benefits of this immunotherapy is still unclear. DESIGN:The aim was to study the influence of paternal lymphocyte...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：:Pregnancy induced hypertension and pre-eclampsia, defined as hypertension and proteinuria after 20 weeks of pregnancy with no history of such symptoms, are a great challenge in the field of perinatology They are a serious threat to the mother and the child. Regardless of numerous studies on the subject, the pathogenes...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：10.17772/gp/1566
更新日期：2013-03-01 00:00:00
abstract：:39 normal fetal heart examinations were evaluated since 20 week of gestation to term, and Doppler blood flow was analysed for mitral and tricuspid valves. The measurements were done always in good 4 chamber view and qualitative and quantitative analysis were performed, in terms of describing E and A waves and maximal ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1993-03-01 00:00:00
abstract：UNLABELLED:Homocysteine (HCY) is an amino acid being a methionin catabolite. The action of HCY is multi-directional and not yet fully known. Follicular fluid also contains homocysteine. Disorders of the composition of follicular fluid as an microenvironment of an oocyte may influence its development. AIM:The aim of ou...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-10-01 00:00:00
abstract：OBJECTIVES:The objective of the study was to investigate the detection rates of Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma urealyticum, Gardnerella vaginalis, Escherichia coli, Streptococcus agalactiae and Enterococcus faecalis, showing no clinical signs of an on...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1588
更新日期：2013-05-01 00:00:00
abstract：:Authors' analysis refers to reasons for which some women did not meet criteria for the programme of collection of cord blood by The Cord Blood Bank in Warsaw. The main reasons were: 1) reactivation of infection with CMV virus, 2) complications of delivery and 3) technical problems. We present also preliminary results ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：:To make use of antigonadotropin and antiproliferating action of the synthetic analogs of GnRH there was applied this decapeptide in 33 patients with ovarian cancer who were treated traditionally by chemotherapeutics PAC and radiotherapy. The monitoring of treatment was supported on the clinical opinion of the whole an...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：:We have analysed 6 cases of twin pregnancies with vertex presentation of the first foetus. In this cases after delivery of the first twin by vaginal route caesarean, section was made. Caesarean section of the second twin was made because of: transversal presentation with fetal distress syndrom (four cases), umbilical ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-11-01 00:00:00
abstract：UNLABELLED:The aim of the study was evaluation, whether cord blood insulin (Ic) and erythropoietin (EPO) levels differ in accordance with mode of delivery: cesarean section (CS) or vaginal delivery (VD). MATERIAL AND METHODS:The study was performed in the diabetic group consisted of 148 newborns of diabetic mothers (N...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1999-10-01 00:00:00
abstract：:14 patients suffered from endometriosis and retroflected uterus were presented. They were treated with laparoscopic ante-fixation of the uterus and Danazol-therapy. Combined treatment was successful, the pain had ceased. ...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：2001-05-01 00:00:00
