当前位置： SCI文献检索 > Ginekologia Polska期刊下所有文献 > Underestimation of breast cancer in intraductal papillomas treated with vacuum-assisted core needle biopsy.

Underestimation of breast cancer in intraductal papillomas treated with vacuum-assisted core needle biopsy.

Abstract：

OBJECTIVES:The aims of the study were as follows: 1) to determine the applicability of vacuum-assisted core needle biopsy in the diagnosis and management of intraductal papillomas of the breast; 2) to define factors which increase the risk for underestimation of breast cancer. MATERIAL AND METHODS:Between 2002-2017, a total of 222 cases of intraductal papillomas were diagnosed in one center (201 using vacuum-assisted core-needle ultrasound-guided biopsy and 21 using stereotactic biopsy). All patients under- went scheduled follow-up imaging. RESULTS:Pure papillomas were diagnosed in 158 women, whereas papillomas with atypia, in this case atypical ductal hyperplasia (ADH), were found in 29 subjects. In the latter group, 3 cases of invasive carcinoma and 5 cases of ductal carci- noma in situ (DCIS) were detected using open surgical biopsy. Breast cancer underestimation in that group of patients was 20%. Overall, ADH, whose presence increases the risk for BC by thirteen-fold as compared to other accompanying lesions, proved to be the most important predictive factor. Also, age, non-radical biopsy excision, and high BI-RADS ultrasound and mammogram scores increased the probability of malignancy. During the control follow-up, no cases of IP recurrence in the primary localization were observed in the group without open surgical biopsy. CONCLUSIONS:Vacuum-assisted core needle biopsy is an efficient tool in the diagnosis and management of intraductal papillomas of the breast. Surgical excision is not indicated in cases when a pure intraductal papilloma, and data correlation between the diagnosis and the clinical presentation were confirmed. Regardless, caution is advised if residual lesions were left and in older populations. Open surgical biopsy should remain the standard of care in cases with atypia and discordance between clinical and pathology data.

journal_name

Ginekol Pol

journal_title

Ginekologia polska

authors

Hodorowicz-Zaniewska D,Siarkiewicz B,Brzuszkiewicz K,Szpor J

doi

10.5603/GP.2019.0022

subject

Has Abstract

pub_date

2019-01-01 00:00:00

pages

122-127

issue

eissn

0017-0011

issn

2543-6767

pii

VM/OJS/J/63171

journal_volume

pub_type

杂志文章

在线工具

Underestimation of breast cancer in intraductal papillomas treated with vacuum-assisted core needle biopsy.