Abstract：
:Matrix metalloproteinases are proteolytic enzymes which degrade extracellular matrix proteins. Along with their specific inhibitors--issue inhibitors of metalloproteinases--they play an important role in the spreading of malignant tumours. The research conducted in recent years has shown that metalloproteinases and their inhibitors contribute substantially to the ovarian cancer progression, participating both in in situ tumours growth, and the spreading of neoplasm via peritoneal fluid. The assessment of serum concentration of some metalloproteinases and their inhibitors appeared to be useful in differential diagnosis between malignant, borderline and benign ovarian tumours. In numerous research, it was revealed that the expression of metalloproteinases in primary tumours and in metastatic changes has a prognostic value. Moreover, the pre-operational assessment of concentration of TIMP-1 in blood serum allows to select the cases of an ovarian cancer with an aggressive phenotype and unfavourable prognosis. Despite great expectations, the usage of synthetic inhibitors of metalloproteinases did not bring significant changes and improvement to ovarian cancer treatment.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Stettner R,Bogusiewicz M,Rechberger Tsubject
Has Abstractpub_date
2009-01-01 00:00:00pages
47-53issue
1eissn
0017-0011issn
2543-6767journal_volume
80pub_type
杂志文章,评审abstract：OBJECTIVE:To analyse deliveries after a previous cesarean section. STUDY DESIGN:The way of birth of 262 patients between 1993-1995 in the Ist Department of Obstetrics and Gynaecology of Warsaw University Hospital was analysed. Material was divided into two groups: an elective cesarean section operation was performed o...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：:A case of a 30 years old pregnant woman suffering from bilateral ovary tumour was presented. When she was sixteen weeks pregnant she had both tumours enucleated using the method of laparoscopy. Diagnostic and therapeutic process have been described. Authors are convinced that laparoscopy as a method of treatment can b...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2005-05-01 00:00:00
abstract：:The role of the peritoneal fluid in the physiology of reproduction, as well as in the transportation and survival of gametes, is little recognized. Taking this into consideration, the authors have examined the occurrence of spermatozoa in the peritoneal fluid, collected from patients during diagnostic laparoscopies, f...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：:This paper sums up the results of treatment with laparoscopy the patients suffering from infertility of unknown reason. Laparoscopy was performed in 75 patients and only in 21.3% of cases the reason of infertility remained unclear. In most of infertile women (90%) different factors of infertility were revealed--among ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：:The retrospective and prospective epidemiological studies were conducted in centres all over the world and showed that the main etiological factor in cervical cancer is human papillomavirus infection. The problem of detection of HPV infection is being currently under discussion. The selection of method of HPV detectio...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2002-08-01 00:00:00
abstract：:The efficiency of glycemia control was compared in two groups of insulin dependent diabetic pregnancies treated with insulin, with and without the aid of the Camit-Diacomp system. The efficiency of glycemia control was analysed in all three trimesters of pregnancy. Mean diurnal fluctuations of glycemia levels in both ...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：1997-03-01 00:00:00
abstract：OBJECTIVES:To assess the effectiveness of the donor-block biopsies with a 2 mm-size needle in endometrioid endometrial cancer (EEC) in the tissue microarray (TMA) technique and the application of the TMA for estrogen receptors (ER) and progesterone receptors (PR) expression in EEC. MATERIAL AND METHODS:The study exami...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2012-05-01 00:00:00
abstract：:The paper concerns the treatment results of 113 women with PCO-S by laparoscopic (102) and microlaparoscopic (11) ovarian electrocautery. All of them were qualified for operation on the basis of the following criteria: menstrual cycle disturbances (oligo-/amenorrhoea), anovulation, hirsutism, obesity, LH/FSH ratio > 2...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：2001-08-01 00:00:00
abstract：OBJECTIVE:To determine if cervical shortening between 12 and 28 weeks gestation predicts risk of spontaneous preterm birth or cervical funneling requiring cerclage. STUDY DESIGN:We reviewed retrospectively all the patients who had transvaginal cervical ultrasound assessment during one year. 43 patients who had a secon...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2005-07-01 00:00:00
abstract：OBJECTIVES:The aims of the study were as follows: 1) to determine the applicability of vacuum-assisted core needle biopsy in the diagnosis and management of intraductal papillomas of the breast; 2) to define factors which increase the risk for underestimation of breast cancer. MATERIAL AND METHODS:Between 2002-2017, a...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2019.0022
更新日期：2019-01-01 00:00:00
abstract：:The HELLP syndrome is a variant of severe preeclampsia. Its leading symptoms are: hemolysis, increased liver enzymes and low platelet count. The treatment of the HELLP syndrome remains controversial as there are no standards of proven efficacy. The article presents a case of a 27- year-old patient, G1P0, 30 wk of gest...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2007-03-01 00:00:00
abstract：UNLABELLED:THE OBJECTIVES: The aim of this study was to evaluate the clinical value of blood flow indicies for differentiating between benign and malignant ovarian tumours. MATERIALS AND METHODS:Realisation of the aim was based on the analysis of examinations' results of 686 ovarian tumors. For each recorded blood flo...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-08-01 00:00:00
abstract：:The article presents general information about activin A, a glycoprotein that belongs to the transforming growth factor beta superfamily. Structure, mechanism and role of activin as a possible marker of hypoxia and intraventricular haemorrhage were described. ...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2009-06-01 00:00:00
abstract：OBJECTIVES:According to the literature the frequency of twins is increasing due to technics af assisted reproduction. Many complications of pregnancy and delivery are more likely to develop during multiple pregnancy. DESIGN:Aim of the study was to analyze labour and delivery in multiple pregnancy and assess the neonat...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2005-03-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to verify clinical diagnosis of cervical incompetence by the use of transvaginal sonography. MATERIAL AND METHODS:101 pregnant women hospitalized at the Pathological Pregnancy Department, Medical University of Lodz in years 2000-2002 because of suspicion of cervical incompetence wer...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2004-07-01 00:00:00
abstract：OBJECTIVES:There are some data concerning homocysteine influence on fertilization and early embryogenesis, especially in women experiencing recurrent pregnancy loss (RSA). However, limited data support hypothesis that the ovum might be exposed to high homocysteine concentration what may be important in egg-sperm intera...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：BACKGROUND:Ductus venosus is the fetal blood vessel connecting the abdominal portion of the umbilical vein with the inferior vena cava. Numerous studies have confirmed the important role of this vessel in fetal circulation. There are, however cases when finding the ductus venosus during an ultrasound examination is imp...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/1623
更新日期：2013-08-01 00:00:00
abstract：:Two cases of unilateral urethral obstruction caused by endometriosis were reported. Two patients aged 48 and 35 years old were fully diagnosed with above mentioned abnormalities prior to a surgical operation. During the surgical operations the initial diagnosis was confirmed macroscopically, followed by the surgical a...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2002-10-01 00:00:00
abstract：INTRODUCTION:The paper discusses the reliability of the Apgar score for evaluating newborns, particularly its usefulness in assessing the state of preterm or full term newborns born with hypoxia. AIM:The paper provides a sum-up of the opinions on usefulness and reliability of the Apgar score given by doctors from 255 ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：OBJECTIVE:The aim of our study was to compare ultrasound vascular blood flow indices with the expression of CD-34 in women with benign and malignant adnexal tumors. MATERIALS AND METHODS:Transvaginal color and pulsed Doppler sonography was performed before surgical procedure in 105 women with adnexal tumors. Blood flo...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：:The purpose of the study was to estimate blood flow in uterine arteries in patients with uterus cervix invasive carcinoma. In the study the colour Doppler ultrasonography was used. It was found out that in the group of patients with uterus cervix carcinoma pulsation index (PI)--1.82 +/- 1.44 as well as resistance inde...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：1995-09-01 00:00:00
abstract：UNLABELLED:The aim of the study was to assess the significance of some perinatal risk factors and neonatal complications in occurrence of nosocomial infections in the population of NICU patients. MATERIAL AND METHODS:Analysis of risk factors was performed in all patients treated in the years 2005-2008 in NICU Departme...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2009-08-01 00:00:00
abstract：INTRODUCTION:Psychological factors are believed to play an important role in infertility and its treatment Psychological problems may be considered to be risk factors and the cause of reduced infertility, as well as contribute to an unsuccessful outcome of infertility treatment. OBJECTIVES:The aim of the study was to ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2008-02-01 00:00:00
abstract：:Investigations covered 64 women in the III trimester of pregnancy. In this group 34 were with diagnosed primary arterial hypertension (examined group), and 30 were apparently healthy (control group). In both groups the blood serum concentrations of creatinine, urea, uric acid and electrolytes were determined. Creatini...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVES:Triplet pregnancies have higher perinatal morbidity and mortality rates than singleton pregnancies. In modern perinatology computer cardiotocography is one of the best methods of fetus state assessment. DESIGN:The research was based on computer analysis of cardiotocograph printouts. MATERIALS AND METHODS:T...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-10-01 00:00:00
abstract：OBJECTIVE:Angiopoietin-related growth factor (AGF) is associated with angiogenesis but it can also affect glucose and energy metabolism. The aim of the study was to determine AGF levels in gestational diabetes mellitus (GDM). MATERIALS AND METHODS:The study included 44 patients with GDM (GDM group) and 33 non-diabetic...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2012-10-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to determine the incidence of placenta previa and to asses the relationship between the incidence of placenta previa and maternal age, parity, prior abortion and cesarean deliveries. MATERIALS AND METHODS:The records of all patients with the diagnosis of placenta previa during t...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2005-04-01 00:00:00
abstract：:Iniencephaly is a rare malformation characterized by the triad of occipital bone defect, cervical dysraphism and fixed retroflexion of the fetal head with poor prognosis. We present a case one of the twin with iniencephaly and congenital heart defect (common atrio-ventricular canal) with normal karyotype. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-06-01 00:00:00
abstract：OBJECTIVES:The aim of the study was the evaluation of repeatability and reproducibility of chosen urethral neck mobility measurements obtained during introital pelvic floor sonography performed with a 2D transvaginal probe. MATERIAL AND METHODS:In order to assess the repeatability and reproducibility, independent meas...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2017.0068
更新日期：2017-01-01 00:00:00
abstract：OBJECTIVES:Clinicopathological study of eleven cases of carcinoma of the fallopian tube to understanding possible risk factors for therapeutic failure. DESIGN:The study group consisted of 11 cases of primary carcinoma of the fallopian tube treated in our Department over 25-year period. Clinical and pathologic data wer...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-09-01 00:00:00
