Abstract：
UNLABELLED:Homocysteine (HCY) is an amino acid being a methionin catabolite. The action of HCY is multi-directional and not yet fully known. Follicular fluid also contains homocysteine. Disorders of the composition of follicular fluid as an microenvironment of an oocyte may influence its development. AIM:The aim of our study was to evaluate correlation between follicular fluid homocysteine concentration and degree of maturity of egg cell. MATERIALS AND METHODS:The research concerned 40 patients qualified for IVF-ET. Ovulation was stimulated according to the long protocol. 20 of 40 patients underwent folic acid supplementation. Pituitary suppression was performed by administration of the nafarelin. The subsequent follicular development was stimulated by HMG. To all patients 10,000 IU of hCG was administered 34-36 hours before follicle puncture. The oocytes obtained were assessed in respect of a degree of Veeck scale. In all patients, fluid samples were recovered from more than one follicle, centrifugated and frozen before analysis. Both in the follicular fluid and serum, homocysteine concentration was determined with the FPIA method. Concentration of the folic was measured with the MEIA method. RESULTS:These data support that homocysteine concentration in follicular fluid and serum was significantly lower in group with folic supplementation. The purpose of the research was to determine the dependencies between the concentration of HCY in follicular fluid and the quality of oocytes. It has been shown that in a group of women with folic supplementation and lower HCY concentration the percentage of oocytes in first and second degree of maturity was higher. CONCLUSIONS:1. Supplementation of folic acid diminish a concentration of homocysteine in both--follicular fluid and serum. 2. Oocytes exposed to low homocysteine concentration present better quality and higher degree of maturity. 3. There is a correlation between follicular fluid homocysteine concentration and oocyte maturity.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Szymański W,Kazdepka-Ziemińska Akeywords:
subject
Has Abstractpub_date
2003-10-01 00:00:00pages
1392-6issue
10eissn
0017-0011issn
2543-6767journal_volume
74pub_type
杂志文章abstract：:During 14 subsequent days male Wistar rats received subcutaneously 50 micrograms of EB and different doses of tamoxifen intratesticularly. Action of EB was examined by comparison with the group, which received the solvent for EB only. EB caused the reduction in the mean testis weight, degenerative changes of germinal ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1994-02-01 00:00:00
abstract：:We were looking for presence, severity and extension of the invasion of vessels, with regard to the prognosis in 275 patient with infiltration limited only to uterine cervix (Ib), in which Wertheim-Meigs surgery was performed. It was found invasion of many vessels- in outside of the cervix is associated with poor prog...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1997-11-01 00:00:00
abstract：:We investigated the vitamin D receptor (VDR) and the estrogen receptor (ER) genes polymorphism in studied groups was similar, however the allelic combination BBPPxx was associated with low bone mineral mass. There is a need to perform genetic test in the cohort of polish women endangered by osteoporosis. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-08-01 00:00:00
abstract：:Basic methods of contraception of unwanted pregnancy are reviewed: mechanical, vaginal devices, hormonal tablets, and IUDs. On the basis of personal experience the author considers that, compared with other methods of contraception, the intrauterine spiral is the safest device for the female organism. An evaluation...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1975-03-01 00:00:00
abstract：OBJECTIVES:G-CSF is a stimulatory factor of granulocyte colony formation. In vitro and in vivo G-CSF stimulates the proliferation of granulocyte precursors and enhances phagocytic functions of mature cells. Indirect evidence of this might be the increase of the activity of granulocyte enzymes participating in phagocyto...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2004-02-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to determine the incidence of placenta previa and to asses the relationship between the incidence of placenta previa and maternal age, parity, prior abortion and cesarean deliveries. MATERIALS AND METHODS:The records of all patients with the diagnosis of placenta previa during t...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2005-04-01 00:00:00
abstract：UNLABELLED:Infertility has been recognized by WHO a disease concerning males and females. It is a serious social problem, therefore the evaluation of its reasons, its prevention and treatment is a subject of clinical studies. OBJECTIVE:To define the reasons of infertility and factors affecting fertility. MATERIAL AND...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2005-12-01 00:00:00
abstract：OBJECTIVES:Human papillomavirus (HPV) ranks the first cause of cervical cancer. Cervical cancer has high prevalence rates in women around the world. The HPV-E7 oncoprotein is expressed in cervical cancer and is a target of developing immunotherapies against HPV-associated tumors. However, the antigenicity of this prote...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2020.0055
更新日期：2020-01-01 00:00:00
abstract：:Childhood and adolescent gynecology is an emerging specialty at the intersection of pediatrics, pediatric endocrinology gynecology pediatric surgery dermatology psychiatry, public health medicine and genetics, and in fact addresses many legal issues. Poland lacks a uniform standing of medical and legal environments on...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：10.17772/gp/1553
更新日期：2013-02-01 00:00:00
abstract：:Placental mesenchymal dysplasia (PMD) is a rare benign vascular anomaly of the placenta. It can be misdiagnosed as a molar pregnancy resulting in unnecessary termination of pregnancy. A 30-year-old woman was referred to our hospital at 18 gestational weeks due to suspicion of molar pregnancy. The ultrasound showed a b...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2020.0129
更新日期：2020-01-01 00:00:00
abstract：:The presence of estrogens, their function and targets in male reproductive tract are still not fully understood. Recent studies, basic and clinical indicate an important role of estrogens during germ cell development. In this study the efforts have been made to immunolocalize aromatase P450 as well as estrogen recepto...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-06-01 00:00:00
abstract：:A group of 15 women between the ages of 24-45 were given intraamiotic does of 40 mg of prostagladin F2alpha (PGF2alpha; Enzaprost) in a single dose so as to terminate pregnancy. These pregnancies, between the 15th- 24th weeks, were terminated for medical reasons. 12 hours elapsed between the time of intraamniotic ad...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1988-09-01 00:00:00
abstract：UNLABELLED:The aim of the study was to compare frequency of four gynecological operations: myomectomy, tubal surgery, cystectomy and operative management of ectopic pregnancy, performed by laparotomy or laparoscopy, by the same team of surgeons. In the years 1994-1997 in Division of Reproduction Poznań University Medic...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-04-01 00:00:00
abstract：OBJECTIVES:The two functions of the lower urinary tract are the filling/storage and emptying. Similarly lower urinary tract symptoms can be subdivided. DESIGN:The aim of the study was the estimation of usefulness of present complaints-voiding history in diagnosis of lower urinary tract dysfunctions. MATERIAL AND METH...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：2001-03-01 00:00:00
abstract：OBJECTIVE:The aim of our study was to compare ultrasound vascular blood flow indices with the expression of CD-34 in women with benign and malignant adnexal tumors. MATERIALS AND METHODS:Transvaginal color and pulsed Doppler sonography was performed before surgical procedure in 105 women with adnexal tumors. Blood flo...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：OBJECTIVES:The ultrasound-guided transversus abdominis plane (TAP) block is a supporting method of pain relief after different types of surgical and gynecological procedures. The aim of the present study was to evaluate the analgesic effects of the TAP-block in patients undergoing caesarean section. MATERIAL AND METHO...
journal_title：Ginekologia polska
pub_type： 杂志文章,随机对照试验
doi：10.5603/GP.a2018.0072
更新日期：2018-01-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1999-10-01 00:00:00
abstract：:Among micro-organisms infecting vagina whose dominant genus is GV anaerobic bacteria are often present. There are reports that GV infections of vagina and uterine cervix, apart from their well-known negative role in obstetrics practice can play a role in carcinogenic processes of uterine cervix. The aim of the study w...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1997-10-01 00:00:00
abstract：:Concentrations of two acute phase proteins: alpha 2-macroglobulin (alpha 2M) and transferrin (Tf) as well as glycosylation profiles of alpha 2M and Tf were studied in sera samples from 13 patients suffering from ovarian cancer. In the observed group of patients with ovarian cancer in whom the progression of disease wa...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：2001-01-01 00:00:00
abstract：OBJECTIVES:To determine the effects of nutritional nursing intervention based on glycemic load (GL) for patients with gestational diabetes mellitus. MATERIAL AND METHODS:One hundred thirty-four patients diagnosed with gestational diabetes mellitus at our hospital were selected from March 2015 to March 2017 and randoml...
journal_title：Ginekologia polska
pub_type： 杂志文章,随机对照试验
doi：10.5603/GP.2019.0007
更新日期：2019-01-01 00:00:00
abstract：UNLABELLED:Gestational Diabetes (GDM) is characterized by insulin resistance and a pro-inflammatory state, both factors possible related to adipokine expression. SUBJECTS AND METHODS:The study included 20 women with GDM, diagnosed according to the WHO criteria, and 23 matched for age and BMI women with normal glucose ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2010-12-01 00:00:00
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journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：2010-11-01 00:00:00
abstract：:Irradiation of cancer diseases with intracavitary applicator makes impossible visual control of applicator's position during the process of irradiation. In this paper example applicator moves during the treatment are presented and their influence to dose distribution especially in reference points is discussed. Verifi...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1992-08-01 00:00:00
abstract：:In polycystic ovarian disease there is a strong association between hyperinsulinemia and hyperandrogenism but not with obesity alone. The magnitude of peripheral insulin resistance is similar to that seen in non-insulin-dependent diabetes mellitus. Mild hyperinsulinemia in PCOD patients is not impair the carbohydrate ...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：1994-10-01 00:00:00
abstract：OBJECTIVES:Intrahepatic cholestasis in pregnancy (ICP) is a pregnancy-specific liver disorder. Its etiology is not fully understood. Increasing evidence indicates the important role of vitamin D and the vitamin D receptor (VDR) in this disorder. The presence of polymorphic variants in the VDR gene could influence its a...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.a2020.0135
更新日期：2020-01-01 00:00:00
abstract：:It was found that amniotic fluid (38-42 Hbd) contains hydroxyproline in concentration about 10 micrograms/ml. Gel filtration and dialysis demonstrated that most of hydroxyproline exists in a form of low molecular weight products. Furthermore, it was found that amniotic fluid contains a protein which eluates during gel...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：:Rarely met pruritic urticarial papules and plaques of pregnancy usually are connected with multiply pregnancy. Disease begins in the third trimester of pregnancy, doesn't react on treating and disappear after delivery. In the reported case massive skin changes disappeared in a few days after caesarean section. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-06-01 00:00:00
abstract：:The terminology quoted in the leaflet "Ultrasonometry of foetus in evaluation of gestational age" could change the diagnostic and therapeutic procedures in obstetrics from the point of view of only one out of many methods of imaging. The object of the study was to complement the "standards for eleven measurements pert...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-02-01 00:00:00
abstract：OBJECTIVE:To evaluate the clinical utility of CA-125 measurements in peritoneal fluid (PF) as an indicator of endometriosis. DESIGN:CA-125 levels in paired serum and peritoneal fluid were assessed by IMx CA-125 Assay (ABBOTT). PATIENTS:107 women with and without endometriosis, undergoing laparoscopy during the luteal...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-12-01 00:00:00
abstract：OBJECTIVE:The purpose of the study was to compare concentrations of inflammatory and Th1/Th2 cytokines in serum obtained from women with preeclampsia or severe pregnancy hypertension versus normotensive controls. MATERIAL AND METHODS:The study group consisted of 34 pregnant women with hypertension over 140/90mmHg and ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2010-03-01 00:00:00
