Abstract：
:It still needs to be elucidated whether co-detection of EV71 with other intestinal tract viruses plays a role in the pathogenesis of severe hand-foot-mouth disease (HFMD). A total of 680 stool specimens collected from clinically diagnosed mild and severe-HFMD patients were tested for EV71, CA16, norovirus, bocavirus and rotavirus. The results showed that EV71 was significantly associated with severe-HFMD patients. Co-detection of EV71 with norovirus and rotavirus was also significantly associated with severe-HFMD patients: The OR (95 % CI) value was 6.466 (2.735, 15.283) and 7.561 (3.560, 16.057), p < 0.001, respectively. Co-detection of EV71 with rotavirus or norovirus is probably associated with severe HFMD.
journal_name
Arch Viroljournal_title
Archives of virologyauthors
Liu LJ,Xu HM,Li XJ,Wang J,Wang XJ,Ding SJ,Tang F,Wang J,Zhang YJdoi
10.1007/s00705-012-1396-6subject
Has Abstractpub_date
2012-11-01 00:00:00pages
2219-22issue
11eissn
0304-8608issn
1432-8798journal_volume
157pub_type
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