Characteristics of fatty acid-binding proteins and their relation to mammary-derived growth inhibitor.

abstract：:The metabolism of D-glucose was characterized in both normal dispersed rat islet cells and the 2-mercaptoethanol-dependent insulin-secreting cells of the INS-1 line. The normal and tumoral islet cells differed from one another by the relative magnitude, concentration dependency and hierarchy of the increase in the pro...

journal_title：Molecular and cellular biochemistry

authors： Nadi AB,Olivares E,Malaisse WJ

更新日期：2000-07-01 00:00:00

abstract：:The aim of the present study was to determine whether heat shock protein 72 (HSP72) is induced in a heated rat model at rectal temperatures below 42 degrees C. Rats were divided into a control group and six groups (n = 6) heated to different rectal temperatures: 39 degrees C for 1 h (39), 40.0 degrees C for either 15 ...

journal_title：Molecular and cellular biochemistry

authors： Ruell PA,Hoffman KM,Chow CM,Thompson MW

更新日期：2004-12-01 00:00:00

abstract：:Inhalation of silica in a number of occupational settings can result in debilitating and costly lung disease. It is thought that the pathological replacement of functional lung tissue with fibrotic lesions in silica-induced lung disease is the result of chronic inflammation mediated by products of the silica-exposed a...

journal_title：Molecular and cellular biochemistry

authors： Chen F,Shi X

更新日期：2002-05-01 00:00:00

abstract：:Parasitic nematodes have recently been found to produce proteins which represent two new classes of fatty acid and retinoid binding protein. The first is the nematode polyprotein allergens/antigens (NPAs) which, as their name suggests, are synthesised as large polyproteins which are subsequently cleaved at regularly s...

journal_title：Molecular and cellular biochemistry

authors： McDermott L,Cooper A,Kennedy MW

更新日期：1999-02-01 00:00:00

abstract：:We have investigated how diabetes affects the expression of adropin (ADR) in rat brain, cerebellum, kidneys, heart, liver, and pancreas tissues. The rats in the diabetic group were administered an intraperitoneal (i.p.) injection of a single dose of 60 mg/kg streptozotocin (STZ) dissolved in a 0.1 M phosphate-citrate ...

journal_title：Molecular and cellular biochemistry

authors： Aydin S,Kuloglu T,Aydin S,Eren MN,Yilmaz M,Kalayci M,Sahin I,Kocaman N,Citil C,Kendir Y

更新日期：2013-08-01 00:00:00

abstract：:The aim of this study was to investigate the interrelationship between the mitochondrial phospholipid cardiolipin (CL), mitochondrial respiration and morphology in dependence on hypoxia/reoxygenation and Ca(2+). Therefore, we subjected rat liver mitochondria to hypoxia/reoxygenation at different extramitochondrial Ca(...

journal_title：Molecular and cellular biochemistry

authors： Martens JC,Keilhoff G,Gardemann A,Schild L

更新日期：2014-09-01 00:00:00

abstract：:Poly(ADP-ribose) polymerases or PARPs are a family of NAD(+)-dependent enzymes that modify themselves and other substrate proteins with ADP-ribose polymers. The founding member PARP 1 is localized predominantly in the nucleus and is activated by binding to DNA lesions. Excessive PARP 1 activation following genotoxin t...

journal_title：Molecular and cellular biochemistry

authors： Yeh TY,Sbodio JI,Nguyen MT,Meyer TN,Lee RM,Chi NW

更新日期：2005-08-01 00:00:00

abstract：:The present study was aimed to investigate the protective effects of 17β-estradiol (E2) and estrogen receptor α (ERα) on isoproterenol (ISO)-treated H9c2 cardiomyoblast cells. In the present study, we treated H9c2 cells with ISO, a β-adrenergic receptor agonist, to induce myocardiac hypertrophy. Pre-administration of ...

journal_title：Molecular and cellular biochemistry

authors： Pai P,Velmurugan BK,Kuo CH,Yen CY,Ho TJ,Lin YM,Chen YF,Lai CH,Day CH,Huang CY

更新日期：2017-10-01 00:00:00

abstract：:In the infarcted rat heart, the increase of NO occurs in the hypertrophied myocardium of non-infarcted areas and its antihypertrophic efficacy has been well established. As another endogenous regulator and the reliable index of heart pathology, B-type natriuretic peptide also exhibits the antihypertrophic properties i...

journal_title：Molecular and cellular biochemistry

authors： Wang T,Yan M,Li J,Zheng X

更新日期：2007-08-01 00:00:00

abstract：:Spray-dried milk enriched with n-3 fatty acids from linseed oil (LSO) or fish oil (FO) were fed to rats to study its influence on liver lipid peroxides, hepatic antioxidant enzyme activities, serum prostaglandins and platelet aggregation. Significant level of alpha linolenic acid, eicosapentaenoic acid and docosahexae...

journal_title：Molecular and cellular biochemistry

authors： Ramaprasad TR,Baskaran V,Krishnakantha TP,Lokesh BR

更新日期：2005-09-01 00:00:00

abstract：:Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are highly reactive transient chemical species, which play an important role in the etiology of tissue injury in rheumatoid arthritis (RA). The effects of milk extract of Semecarpus anacardium Linn. nut (SA) was studied on adjuvant arthritis in rats. Ar...

journal_title：Molecular and cellular biochemistry

authors： Ramprasath VR,Shanthi P,Sachdanandam P

更新日期：2005-08-01 00:00:00

abstract：:The effects of the microtubular inhibitor, podophyllotoxin, on mitochondrial respiration were determined using isolated, digitonin-permeabilized hepatocytes and isolated mitochondria. In hepatocytes, podophyllotoxin (1.5 mM) inhibited coupled and uncoupled respiration of both FAD and NAD-linked substrates. In mitochon...

journal_title：Molecular and cellular biochemistry

authors： Horrum MA,Jennett RB,Ecklund RE,Tobin RB

更新日期：1986-06-01 00:00:00

abstract：:The incidence of anxiety-related diseases is increasing these days, hence there is a need to understand the mechanisms that underlie its nature and consequences. It is known that limbic structures, mainly the prefrontal cortex and amygdala, are involved in the processing of anxiety, and that projections from prefronta...

journal_title：Molecular and cellular biochemistry

authors： Mejia-Carmona GE,Gosselink KL,Pérez-Ishiwara G,Martínez-Martínez A

更新日期：2015-08-01 00:00:00

abstract：:Proteoglycans carrying chondroitin sulfate side chains have been shown to fulfill important biological functions in development, disease, and signaling. One area of considerable interest is the functional importance of chondroitin sulfates as inhibitors of the regeneration of axonal projections in the mammalian centra...

journal_title：Molecular and cellular biochemistry

authors： Klüppel M

更新日期：2011-05-01 00:00:00

abstract：UNLABELLED:Inhibition of Na+/H+ exchange with amiloride analogues has been shown to provide functional protection during ischemia and reperfusion and to reduce infarct size in isolated rat hearts. In rat hearts, treatment with ethylisopropyl-amiloride (EIPA, a selective Na+/H- exchange inhibitor) was additive to the pr...

journal_title：Molecular and cellular biochemistry

authors： Munch-Ellingsen J,Løkebø JE,Bugge E,Ytrehus K

更新日期：1998-09-01 00:00:00

abstract：:Peroxisome proliferator activated receptor gamma coactivator 1α (PGC-1α) induced by hypoxia regulates mitochondrial biogenesis and oxidative stress. However, the potential role of PGC-1α in hypoxia-promoted proliferation of pulmonary arterial vascular smooth muscle cells (PASMCs) is completely unknown. In this study, ...

journal_title：Molecular and cellular biochemistry

authors： Rao J,Li J,Liu Y,Lu P,Sun X,Sugumaran PK,Zhu D

更新日期：2012-08-01 00:00:00

abstract：:Studies have established that major increases in muscarinic acetylcholine receptor (mAchR) binding in the brain appear to coincide with synaptogenesis. The neuroblastoma x glioma hybrid NG108-15 cell line has been demonstrated to possess numerous functional characteristics of intact neurons, including synapse formatio...

journal_title：Molecular and cellular biochemistry

authors： Ghahary A,Cheng KW

更新日期：1989-04-11 00:00:00

abstract：:Tripeptide aminopeptidase (EC 3.4.11.4) was purified from bovine dental follicles by a series of chromatographies. Purified enzyme had a specific activity of 59.5 units per mg protein with L-prolyl-glycylglycine as substrate. The pH optimum was 8.0. The purified native enzyme had a Mr of 230,000 and was shown to be a ...

journal_title：Molecular and cellular biochemistry

authors： Hiraoka BY,Harada M

更新日期：1993-12-08 00:00:00

abstract：:Sialomucins are abundant on the surfaces of certain ascites tumor cells and have been implicated in the escape of tumors from immune destruction and metastasis. They are large, highly glycosylated glycoproteins which are rich in serine and threonine and have a variety of 0-linked oligosaccharides. The sialomucin (ASGP...

journal_title：Molecular and cellular biochemistry

authors： Carraway KL,Spielman J

更新日期：1986-11-01 00:00:00

abstract：:TGR(mREN2)27 is a transgenic rat harboring the murine Ren-2 gene and exhibit fulminant hypertension and marked heart hypertrophy. In order to study the role of angiotensin II in the increase of cardiac mass, these animals were treated with antihypertensive and non-antihypertensive doses of the angiotensin II receptor ...

journal_title：Molecular and cellular biochemistry

authors： Böhm M,Lippoldt A,Wienen W,Ganten D,Bader M

更新日期：1996-10-01 00:00:00

abstract：:We have demonstrated that in normal and b/b rat red blood cells (RBCs) hsp70-like protein (heat shock protein 70-like) is localized in the cytosol and it is exported via exosomes during in vivo reticulocytes maturation. As we have presumed, in the mutant (b/b) rat, hsp70-like protein transfers from cytosol to the RBC ...

journal_title：Molecular and cellular biochemistry

authors： Zarić J,Glisin V,Popović Z

更新日期：1998-01-01 00:00:00

abstract：:Radioprotection by an aqueous extract of Podophyllum hexandrum (RP-1) was investigated in HepG2 cells by evaluating colony forming efficacy (CFE), redox status of mitochondria, reactive oxygen species (ROS), generation of nitric oxide (NO), peroxidation of lipids and intracellular glutathione. Lower concentrations of ...

journal_title：Molecular and cellular biochemistry

authors： Gupta D,Arora R,Garg AP,Goel HC

更新日期：2003-08-01 00:00:00

abstract：:A simple method is described for the isolation of crystalline pyruvate kinase from human skeletal muscle. The enzyme was purified by ammonium sulfate fractionation, heat treatment and crystallization. Two crystal forms of pyruvate kinase differing in solubility but not in specific activity were found. The homogenous e...

journal_title：Molecular and cellular biochemistry

authors： Baranowska B,Baranowski T

更新日期：1975-03-27 00:00:00

abstract：:Human and bovine nasal proteoglycan complex components were prepared in parallel. Some molecular properties of human and bovine proteoglycan subunits (PGS) were compared. Two major human "link-like proteins" have been characterized and purified; their compositions and molecular weights were very similar to those obser...

journal_title：Molecular and cellular biochemistry

authors： Périn JP,Bonnet F,Jollès P

更新日期：1978-11-01 00:00:00

abstract：:A highly purified preparation of filamentous hemagglutinin (FHA) from Bordetella pertussis was analyzed for its protein composition by gel electrophoretic methods. In this preparation of FHA the following native species could be detected by polyacrylamide gel electrophoresis (PAGE) at pH 3.2: S1 and S2 (inactive subun...

journal_title：Molecular and cellular biochemistry

authors： An der Lan B,Cowell JL,Burstyn DG,Manclark CR,Chrambach A

更新日期：1986-04-01 00:00:00

abstract：:In mammals, protein kinase CK2 has two isozymic forms of its catalytic subunit, designated CK2alpha and CK2alpha'. CK2alpha and CK2alpha' exhibit extensive similarity within their catalytic domains but have completely unrelated C-terminal sequences. To systematically examine the cellular functions of each CK2 isoform ...

journal_title：Molecular and cellular biochemistry

authors： Litchfield DW,Bosc DG,Canton DA,Saulnier RB,Vilk G,Zhang C

更新日期：2001-11-01 00:00:00

abstract：:The ability of the gap junction phosphoprotein connexin-43 (Cx43) to inhibit DNA synthesis in primary cardiomyocytes is regulated by serine (S) 262, a protein kinase C phosphorylation site that also affects metabolic coupling. We have now examined if the S262-regulated growth suppression is operating in transformed ce...

journal_title：Molecular and cellular biochemistry

authors： Dang X,Jeyaraman M,Kardami E

更新日期：2006-09-01 00:00:00

abstract：:Calycopterin is a flavonoid compound isolated from Dracocephalum kotschyi that has multiple medical uses, as an antispasmodic, analgesic, anti-hyperlipidemic, and immunomodulatory agents. However, its biological activity and the mechanism of action are poorly investigated. Herein, we investigated the apoptotic effect ...

journal_title：Molecular and cellular biochemistry

authors： Esmaeili MA,Farimani MM,Kiaei M

更新日期：2014-12-01 00:00:00

abstract：:Purpurogallin (PPG) is a phenolic compound extracted from nutgalls formed on oak trees. It has been used as an additive to edible or nonedible oils or fats, and to hydrocarbon fuels or lubricants to retard their oxidation. We investigated by luminol-dependent chemiluminescence (PMNL-CL), the ability of PPG to scavenge...

journal_title：Molecular and cellular biochemistry

authors： Prasad K,Kapoor R,Lee P

更新日期：1994-10-12 00:00:00

abstract：:Tyrosine levels are abnormally elevated in tissues and physiological fluids of patients with inborn errors of tyrosine catabolism, especially in tyrosinemia type II, which is caused by deficiency of tyrosine aminotransferase and provokes eyes, skin, and central nervous system disturbances. Considering that the mechani...

journal_title：Molecular and cellular biochemistry

authors： de Andrade RB,Gemelli T,Rojas DB,Funchal C,Dutra-Filho CS,Wannmacher CM

更新日期：2012-05-01 00:00:00