NF-kappaB, a pivotal transcription factor in silica-induced diseases.

abstract：:Oxidized LDL is highly atherogenic as it stimulates macrophage cholesterol accumulation and foam cell formation, it is cytotoxic to cells of the arterial wall and it stimulates inflammatory and thrombotic processes. LDL oxidation can lead to its subsequent aggregation, which further increases cellular cholesterol accu...

journal_title：Molecular and cellular biochemistry

authors： Aviram M,Fuhrman B

更新日期：1998-11-01 00:00:00

abstract：:Physiological responses to high altitude hypoxia are complex and involve a range of mechanisms some of which occur within minutes of oxygen deprivation while others reset a cascade of biosynthetic and physiological programs within the cellular milieu. The O2 sensitive events occur at various organisational levels in t...

journal_title：Molecular and cellular biochemistry

authors： Sarkar S,Banerjee PK,Selvamurthy W

更新日期：2003-11-01 00:00:00

abstract：:Glomerular mesangial cells play an important role in the development of glomerulosclerosis. Mesangial cell apoptosis has been shown to be involved in different stages of development of glomerulonephritis. The aim of the present study was to evaluate the effect of inhibition of serine/threonine phosphatases by okadaic ...

journal_title：Molecular and cellular biochemistry

authors： Parameswaran N,Spielman WS,Brooks DP,Nambi P

更新日期：2004-05-01 00:00:00

abstract：:The effects of purified Ca2+, phospholipid-dependent protein kinase (C-kinase) were studied on adenylate cyclase activity from rat brain striatum. C-kinase treatment of the membranes stimulated adenylate cyclase activity, the maximal stimulation between 50-80% was observed at 3.5 U/ml, whereas the catalytic subunit of...

journal_title：Molecular and cellular biochemistry

authors： Anand-Srivastava MB,Srivastava AK

更新日期：1990-01-18 00:00:00

abstract：:The effect of anti-regucalcin monoclonal antibody on neutral phoshatase activity in rat liver cytosol was investigated. Phosphotyrosine, phosphoserine, and phosphothreonine were used as the substrate toward phosphatase assay. Liver cytosolic phosphatase activity with three phosphoaminoacids was significantly increased...

journal_title：Molecular and cellular biochemistry

authors： Omura M,Yamaguchi M

更新日期：1999-07-01 00:00:00

abstract：:Epidermal growth factor (EGF)-like family members mediate a wide range of biological activities including cell proliferation and migration. Increasing evidence indicated that EGF plays an important role in the process of wound healing by stimulating fibroblast motility. The aim of this study was to see whether EGF-lik...

journal_title：Molecular and cellular biochemistry

authors： Yang RH,Qi SH,Ruan SB,Lin ZP,Lin Y,Zhang FG,Chen XD,Xie JL

更新日期：2016-12-01 00:00:00

abstract：:Histone H1 of rat alveolar macrophages, neutrophilic granulocytes and monocytes extracted with 5% (v/v) perchloric acid was studied in order to see whether a protein similar to histone H1 degrees of rat liver exists in these specialized cells. The biochemical methods used involved SDS and acid-urea polyacrylamide gel ...

journal_title：Molecular and cellular biochemistry

authors： Ghadam P,Rabbani A

更新日期：2002-07-01 00:00:00

abstract：:1. Glucokinase is one of four glucose phosphorylating enzymes present in rat liver. Its distinctive features are a high K-m for glucose (high-K-m isozyme) and a rather narrow substrate specificity. In contrast, the other three enzymes, collectively called hexokinases or low-K-m isozymes, exhibit low K-m values for glu...

journal_title：Molecular and cellular biochemistry

authors： Niemeyer H,Ureta T,Clark-Turri L

更新日期：1975-02-28 00:00:00

abstract：:Myofibroblasts are metabolically and morphologically distinctive fibroblasts expressing alpha-smooth muscle actin (alpha-SMA), and their activation plays a key role in development of the fibrotic response. In an activated state, myofibroblasts cease to proliferate and start to synthesize large amounts of extracellular...

journal_title：Molecular and cellular biochemistry

authors： Nakatani T,Honda E,Hayakawa S,Sato M,Satoh K,Kudo M,Munakata H

更新日期：2008-01-01 00:00:00

abstract：:Angiotensin II has previously been reported to have in vivo and in vitro cardiac hypertrophic effects. We used the salt-sensitive Dahl rat genetic strain to separate mechanical (pressure overload) vs. hormonal (renin-angiotensin system) input in cardiac hypertrophy. Blood pressure was significantly increased and left ...

journal_title：Molecular and cellular biochemistry

authors： Peeler TC,Baker KM,Esmurdoc CF,Chernin MI

更新日期：1991-05-29 00:00:00

abstract：:Cervical cancer remains the second leading cause of gynecologic cancer-related mortality among women worldwide. STING (stimulator of interferon genes) was reported to be involved in the immune surveillance of tumors. However, the specific role of STING in cervical cancer remains unclear. In this study, we found that t...

journal_title：Molecular and cellular biochemistry

authors： Shi F,Su J,Wang J,Liu Z,Wang T

更新日期：2020-11-03 00:00:00

abstract：:A literature search has been conducted to see to what extent steady-state kinetics studies in the period 1965-1976 have revealed deviations from Michaelis-Menten kinetics. It was found that over 800 enzymes have been reported as giving complex curves for a variety of reasons and a group by group classification of all ...

journal_title：Molecular and cellular biochemistry

authors： Hill CM,Waight RD,Bardsley WG

更新日期：1977-05-03 00:00:00

abstract：:It is well established that severe hypertrophy induces metabolic and structural changes in the heart which result in enhanced susceptibility to ischemic damage during cardioplegic arrest while much less is known about the effect of cardioplegic arrest on moderately hypertrophied hearts. The aim of this study was to el...

journal_title：Molecular and cellular biochemistry

authors： Smolenski RT,Jayakumar J,Seymour AM,Yacoub MH

更新日期：1998-03-01 00:00:00

abstract：:Some properties of a submitochondrial cell-free system for protein synthesis are described. The system was prepared from rat liver mitochondria lysed with Triton X-100, and the lysate was characterized by a linear rate of [14C]amino acid incorporation for 15-20 min with subsequent decline in activity. The incorporatio...

journal_title：Molecular and cellular biochemistry

authors： Kisselev OI,Gaitskhoki VS,Neifakh SA

更新日期：1977-02-04 00:00:00

abstract：:Liver cytosol from adrenalectomized rats was prebound for 2 hr at 4 degrees C with unlabeled 10(-5) M corticosterone. After treatment of cytosol with dextran-coated charcoal to remove free steroid, samples were incubated at 15-25 degrees C in the presence of 10 mM molybdate plus 5 mM dithiothreitol (followed by a 60 m...

journal_title：Molecular and cellular biochemistry

authors： Hubbard JR,Tanvir,Shirwany A,Kalimi M

更新日期：1985-01-01 00:00:00

abstract：:The contribution of anti-inflammatory property of celecoxib in the improvement of metabolic disorders in cancer is unknown. The purpose of this study was to compare the effects of celecoxib and ibuprofen, non-steroidal anti-inflammatory drugs (NSAIDs), on several metabolic changes observed in Walker-256 tumor-bearing ...

journal_title：Molecular and cellular biochemistry

authors： de Souza CO,Kurauti MA,de Fatima Silva F,de Morais H,Borba-Murad GR,de Andrade FG,de Souza HM

更新日期：2015-01-01 00:00:00

abstract：:Studies have shown that long noncoding RNA Zinc finger E-box-binding homeobox 2 antisense RNA 1 (ZEB2-AS1) is involved in the progression of lung cancer, bladder cancer, and hepatocellular carcinoma. However, its role in the pathogenesis of gastric cancer remains unknown. The Wnt/β-catenin pathway contributes to the d...

journal_title：Molecular and cellular biochemistry

authors： Wang F,Zhu W,Yang R,Xie W,Wang D

更新日期：2019-06-01 00:00:00

abstract：:A preparation of UDP-GalNAc:sialosyl lactosylceramide N-acetylgalactosaminyl transferase (E.C. 2.4.1.92) obtained from 14-day chick embryo brain was delipidated partially by treatment with cold acetone in the presence of varying amounts of sodium dodecyl sulphate (SDS). The lipid content and the enzyme activity of the...

journal_title：Molecular and cellular biochemistry

authors： Cortassa S,Maccioni HJ

更新日期：1989-01-23 00:00:00

abstract：:Adipose-derived stem cells (ADSCs) have been considered as the optimal cells for regenerative medicine because ADSCs have the potential of multi-directional differentiation. To study the mechanisms of ADSCs differentiation, we analyzed microarray of GSE37329. GSE37329 was downloaded from Gene Expression Omnibus includ...

journal_title：Molecular and cellular biochemistry

authors： Ren Y,Han C,Wang J,Jia Y,Kong L,Eerdun T,Wu L,Jiang D

更新日期：2015-02-01 00:00:00

abstract：:Rat thymocytes, spleen lymphocytes and isolated nuclei were incubated with fatty acids and then labelled with 5-doxylstearic acid and 12-doxylstearic acid. The ESR spectra only in the case of 5-doxylstearic acid showed changes which were demonstrable only under those conditions which resulted in cytolysis. Thymocytes ...

journal_title：Molecular and cellular biochemistry

authors： Burton AF,Piette LH

更新日期：1983-01-01 00:00:00

abstract：:The effect of beta-alanyl-L-histidinato zinc (AHZ) on protein components in osteoblastic MC3T3-E1 cells was investigated. Cells were cultured for 3 days at 37 degrees C in CO2 incubator in plastic dishes containing alpha-modified minimum essential medium supplemented with 10% fetal bovine serum. After the cultures, th...

journal_title：Molecular and cellular biochemistry

authors： Yamaguchi M,Hashizume M

更新日期：1994-07-27 00:00:00

abstract：:Mesenchymal stem cells (MSCs) have the potential for self-renewal and multipotential differentiation to regenerate damaged tissues or recover functional absence in diseases. Superparamagnetic iron oxide nanoparticles (SPIONs) are used as contrast agents in magnetic resonance imaging (MRI) for labeling cells in vitro a...

journal_title：Molecular and cellular biochemistry

authors： Zeng G,Wang G,Guan F,Chang K,Jiao H,Gao W,Xi S,Yang B

更新日期：2011-11-01 00:00:00

abstract：:Pluripotent stem cells within the adipose stromal compartment, termed adipose-derived stromal cells (ASCs), have the potential to differentiate into a variety of cell lineages both in vitro and in vivo. Imaging with expression of exogenous or endogenous green fluorescent protein (GFP) reporters facilitates the detaile...

journal_title：Molecular and cellular biochemistry

authors： Lin Y,Tian W,Chen X,Yan Z,Li Z,Qiao J,Liu L,Tang W,Zheng X

更新日期：2005-09-01 00:00:00

abstract：:Sirtuin 3 (SIRT3) modulates mitochondria-localized processes and is implicated in the metabolic reprogramming of cancer cells, especially fatty acid (FA) synthesis. However, the relationship between SIRT3 and aberrant lipid synthesis in cervical cancer remains unclear. Here, we investigated the clinical relevance of S...

journal_title：Molecular and cellular biochemistry

authors： Xu LX,Hao LJ,Ma JQ,Liu JK,Hasim A

更新日期：2020-01-01 00:00:00

abstract：:When Leishmania donovani promastigote forms, were cultured in TC-199 medium at 28 degrees C and subsequently incubated at 38 degrees C, they turned into aflagellate (amastigote-like) forms. A return of the incubation-culture temperature to 28 degrees C these amastigote-like forms to revert to promastigotes. The amasti...

journal_title：Molecular and cellular biochemistry

authors： Castilla JJ,Sanchez-Moreno M,Mesa C,Osuna A

更新日期：1995-01-26 00:00:00

abstract：:SG2NA is a protein of the striatin family that organizes STRIPAK complexes. It has splice variants expressing differentially in tissues. Its 78 kDa isoform regulates cell cycle, maintains homeostasis in the endoplasmic reticulum, and prevents oxidative injuries. The 35 kDa variant is devoid of the signature WD-40 repe...

journal_title：Molecular and cellular biochemistry

authors： Gupta R,Kumar G,Jain BP,Chandra S,Goswami SK

更新日期：2020-10-20 00:00:00

abstract：:The present study was designed to induce massive accumulation of calcium in the myocardium and to evaluate the effect of calcium overload on myocardial contractile function and biochemical activity of cardiac subcellular membranes. Rats were treated with an oral administration of 500,000 units/kg of vitamin D3 for 3 c...

journal_title：Molecular and cellular biochemistry

authors： Takeo S,Tanonaka R,Tanonaka K,Miyake K,Hisayama H,Ueda N,Kawakami K,Tsumura H,Katsushika S,Taniguchi Y

更新日期：1991-10-16 00:00:00

abstract：:L-Asparaginase activity reaches maximal values at the stationary phase of growth of Tetrahymena pyriformis and fluctuates upon the growth conditions and the composition of the medium. Most of the L-asparaginase activity (80%) is associated with the endoplasmic reticulum, and the remaining with the pellicles. Detergent...

journal_title：Molecular and cellular biochemistry

authors： Triantafillou DJ,Georgatsos JG,Kyriakidis DA

更新日期：1988-05-01 00:00:00

abstract：:The present review is focused on the main achievements realized in the lysozyme research field since the meeting held in 1972 to commemorate the fiftieth anniversary of the discovery of this enzyme. Despite of extensive structural, physico-chemical, crystallographic, genetic, immunological and evolutionary studies dev...

journal_title：Molecular and cellular biochemistry

authors： Jollès P,Jollès J

更新日期：1984-09-01 00:00:00

abstract：:Insulin and vanadate function as complete mitogens for SV40-transformed murine 3T3T (CSV3-1) cells but not for nontransformed 3T3T cells. Mitogenesis induced by insulin and vanadate in CSV3-1 cells is associated with the induction of the expression of protooncogenes c-jun and junB, two major AP-1 transcription factor ...

journal_title：Molecular and cellular biochemistry

authors： Wang H,Xie Z,Scott RE

更新日期：1997-03-01 00:00:00