Type C virus and immunoglobulin A production by murine myeloma MOPC-315: two independent activities.

abstract：:Streptococcus pneumoniae, a Gram-positive bacterial pathogen, causes pneumonia, meningitis, and septicemia. Innate immune responses are critical for the control and pathology of pneumococcal infections. It has been demonstrated that S. pneumoniae induces the production of type I interferons (IFNs) by host cells and th...

journal_title：Infection and immunity

authors： Fang R,Hara H,Sakai S,Hernandez-Cuellar E,Mitsuyama M,Kawamura I,Tsuchiya K

更新日期：2014-06-01 00:00:00

abstract：:Vibrio parahaemolyticus is a leading cause of seafood-borne gastroenteritis; however, its virulence mechanisms are not well understood. The identification of type III secreted proteins has provided candidate virulence factors whose functions are still being elucidated. Genotypic strain variability contributes a level ...

journal_title：Infection and immunity

authors： Casselli T,Lynch T,Southward CM,Jones BW,DeVinney R

更新日期：2008-05-01 00:00:00

abstract：:Vibrio parahaemolyticus, a gram-negative marine bacterium, is an important pathogen causing food-borne gastroenteritis or septicemia. Recent genome sequencing of the RIMD2210633 strain (a Kanagawa phenomenon-positive clinical isolate of serotype O3:K6) revealed that the strain has two sets of gene clusters that encode...

journal_title：Infection and immunity

authors： Ono T,Park KS,Ueta M,Iida T,Honda T

更新日期：2006-02-01 00:00:00

abstract：:Brucella spp. are gram-negative intracellular pathogens that survive and multiply within phagocytic cells of their hosts. Smooth organisms present O polysaccharides (OPS) on their surface. These OPS help the bacteria avoid the bactericidal action of serum. The wboA gene, coding for the enzyme glycosyltransferase, is e...

journal_title：Infection and immunity

authors： Fernandez-Prada CM,Nikolich M,Vemulapalli R,Sriranganathan N,Boyle SM,Schurig GG,Hadfield TL,Hoover DL

更新日期：2001-07-01 00:00:00

abstract：:Trefoil family factor 2 (TFF2), also known as spasmolytic peptide, is a low-molecular-weight protein that is upregulated in gastric tissues infected with Helicobacter or having other inflammatory conditions, but a precise function is yet to be elucidated. The role of TFF2 in the development of gastritis, colitis, and ...

journal_title：Infection and immunity

authors： Kurt-Jones EA,Cao L,Sandor F,Rogers AB,Whary MT,Nambiar PR,Cerny A,Bowen G,Yan J,Takaishi S,Chi AL,Reed G,Houghton J,Fox JG,Wang TC

更新日期：2007-01-01 00:00:00

abstract：:Escherichia coli O157:H7 is an important pathogen of humans. Cattle are most frequently identified as the primary source of infection, and therefore, reduction in E. coli O157:H7 prevalence in cattle by vaccination represents an attractive strategy for reducing the incidence of human disease. H7 flagella have been imp...

journal_title：Infection and immunity

authors： McNeilly TN,Naylor SW,Mahajan A,Mitchell MC,McAteer S,Deane D,Smith DG,Low JC,Gally DL,Huntley JF

更新日期：2008-06-01 00:00:00

abstract：:Legionnaires' disease is clinically manifested as severe pneumonia caused by Legionella pneumophila. However, the dendritic cell (DC)-centered immunological framework of the host defense against L. pneumophila has not been fully delineated. For this study, we focused on a potent chemoattractant for lymphocytes, fracta...

journal_title：Infection and immunity

authors： Kikuchi T,Andarini S,Xin H,Gomi K,Tokue Y,Saijo Y,Honjo T,Watanabe A,Nukiwa T

更新日期：2005-09-01 00:00:00

abstract：:In a previous study we showed that the involvement of EP4 subtype of the prostaglandin E (PGE) receptor is crucial for lipopolysaccharide (LPS)-induced osteoclast formation in vitro. The present study was undertaken to test whether EP4 is actually associated with LPS-induced bone resorption in vivo. In wild-type (WT) ...

journal_title：Infection and immunity

authors： Sakuma Y,Tanaka K,Suda M,Komatsu Y,Yasoda A,Miura M,Ozasa A,Narumiya S,Sugimoto Y,Ichikawa A,Ushikubi F,Nakao K

更新日期：2000-12-01 00:00:00

abstract：:Urogenital Chlamydia serovars replicating in reproductive epithelium pose a unique challenge to host immunity and vaccine development. Previous studies have shown that CD4 T cells are necessary and sufficient to clear primary Chlamydia muridarum genital tract infections in the mouse model, making a protective CD4 T ce...

journal_title：Infection and immunity

authors： Johnson RM,Yu H,Kerr MS,Slaven JE,Karunakaran KP,Brunham RC

更新日期：2012-06-01 00:00:00

abstract：:We developed an efficient electrotransformation system for the pathogenic fungus Histoplasma capsulatum and used it to examine the effects of features of the transforming DNA on transformation efficiency and fate of the transforming DNA and to demonstrate fungal expression of two recombinant Escherichia coli genes, hp...

journal_title：Infection and immunity

authors： Woods JP,Heinecke EL,Goldman WE

更新日期：1998-04-01 00:00:00

abstract：:Three antigenic determinants were revealed in H3 hemagglutinin of influenza A viruses isolated from 1968 to 1975. One of them was common for all viruses, and two others specified differences between the viruses possessing H3 hemagglutinin. ...

journal_title：Infection and immunity

authors： Rovnova ZI,Kosyakov PN,Berezina ON,Isayeva EI,Zhdanov VM

更新日期：1979-06-01 00:00:00

abstract：:Vibrio cholerae causes human infection through ingestion of contaminated food and water, leading to the devastating diarrheal disease cholera. V. cholerae forms matrix-encased aggregates, known as biofilms, in the native aquatic environment. While the formation of V. cholerae biofilms has been well studied, little is ...

journal_title：Infection and immunity

authors： Hay AJ,Zhu J

更新日期：2015-01-01 00:00:00

abstract：:Strains of indigenous Escherichia coli, Bacteroides, and Lactobacillus were isolated from the gastrointestinal tracts of specific pathogen-free (SPF) mice. Nonvaccinated SPF mice exhibited in their spleens low numbers of plaque-forming cells (PFC) and rosette-forming cells reacting with antigens of these andigenous ba...

journal_title：Infection and immunity

authors： Berg RD,Savage DC

更新日期：1975-02-01 00:00:00

abstract：:Lactoperoxidase catalyzes the oxidation of thiocyanate by hydrogen peroxide into hypothiocyanite, a reaction which can protect bacterial and mammalian cells from killing by hydrogen peroxide. The present study demonstrates, however, that lactoperoxidase in the presence of thiocyanate can actually potentiate the bacter...

journal_title：Infection and immunity

authors： Carlsson J,Edlund MB,Hänström L

更新日期：1984-06-01 00:00:00

abstract：:Macrophage recognition of Salmonella enterica serovar Typhimurium leads to a cascade of signaling events, including the activation of Src family and Syk kinases and the production of reactive oxygen species (ROS), which are critical for host innate defense during early stages of bacterial infection. ROS production dep...

journal_title：Infection and immunity

authors： Charles JF,Humphrey MB,Zhao X,Quarles E,Nakamura MC,Aderem A,Seaman WE,Smith KD

更新日期：2008-06-01 00:00:00

abstract：:Indoleamine 2,3-dioxygenase (IDO), a tryptophan-degrading enzyme, is inducible by various interferons (IFNs). IDO-mediated tryptophan degradation, but not the formation of IDO-catalyzed tryptophan metabolites, has been suggested as a mechanism for the antiparasitic action of IFN-gamma. To determine whether the IFN-gam...

journal_title：Infection and immunity

authors： Habara-Ohkubo A,Shirahata T,Takikawa O,Yoshida R

更新日期：1993-05-01 00:00:00

abstract：:Cryptococcus neoformans is an opportunistic fungal pathogen that primarily causes disease in immunocompromised individuals. Dendritic cells (DCs) can phagocytose C. neoformans, present cryptococcal antigen, and kill C. neoformans. However, early events following C. neoformans phagocytosis by DCs are not well defined. ...

journal_title：Infection and immunity

authors： Wozniak KL,Levitz SM

更新日期：2008-10-01 00:00:00

abstract：:Conventional adult mice were pretreated with metronidazole to make their intestinal tracts receptive to colonization by Clostridium botulinum. These mice, in groups of 10, were fed 0 (controls), 10(2), 10(3), 10(4), or 10(5) C. botulinum type B spores and were placed for observation in filter-lid cages whose screen fl...

journal_title：Infection and immunity

authors： Wang Y,Sugiyama H

更新日期：1984-12-01 00:00:00

abstract：:The complete sequence analysis of the 210-kb Shigella flexneri 5a virulence plasmid was determined. Shigella spp. cause dysentery and diarrhea by invasion and spread through the colonic mucosa. Most of the known Shigella virulence determinants are encoded on a large plasmid that is unique to virulent strains of Shigel...

journal_title：Infection and immunity

authors： Venkatesan MM,Goldberg MB,Rose DJ,Grotbeck EJ,Burland V,Blattner FR

更新日期：2001-05-01 00:00:00

abstract：:The gram-negative gastric pathogen Helicobacter pylori is equipped with an extraordinarily large set of outer membrane proteins (OMPs), whose role in the infection process is not well understood. The Hop (Helicobacter outer membrane porins) and Hor (Hop-related proteins) groups constitute a large paralogous family con...

journal_title：Infection and immunity

authors： Odenbreit S,Swoboda K,Barwig I,Ruhl S,Borén T,Koletzko S,Haas R

更新日期：2009-09-01 00:00:00

abstract：:Stenotrophomonas maltophilia is a ubiquitous bacterium and an emerging nosocomial pathogen. This bacterium is resistant to many antibiotics, associated with a number of infections, and a significant health risk, especially for immunocompromised patients. Given that Caenorhabditis elegans shares many conserved genetic ...

journal_title：Infection and immunity

authors： White CV,Darby BJ,Breeden RJ,Herman MA

更新日期：2015-12-07 00:00:00

abstract：:The abilities of six strains of Mycobacterium bovis strain BCG to replicate in vivo and to cause spleen enlargement in the CDF(1) male mouse were compared. The strains were grown in synthetic medium and harvested soon after complete pellicles were produced on liquid medium. In addition, two freeze-dried commercially a...

journal_title：Infection and immunity

authors： Sher NA,Chaparas SD,Pearson J,Chirigos M

更新日期：1973-11-01 00:00:00

abstract：:Rabbit lymphoid cells from spleen, peripheral blood, and peritoneal cavity lacked killer (K)-cell activity against cell lines of rabbit and human origin, including virus-infected human tumor cells. This lack of activity was not affected by antibody concentration, source of antibodies, effector/target cell ratio, or le...

journal_title：Infection and immunity

authors： Karavodin LM,Sidell N,Woan MC,Tompkins WA

更新日期：1982-02-01 00:00:00

abstract：:Toll-like receptors and Nod-like receptors (NLR) play an important role in sensing invading microorganisms for pathogen clearance and eliciting adaptive immunity for protection against rechallenge. Nod1 and Nod2, members of the NLR family, are capable of detecting bacterial peptidoglycan motifs in the host cytosol for...

journal_title：Infection and immunity

authors： Loving CL,Osorio M,Kim YG,Nuñez G,Hughes MA,Merkel TJ

更新日期：2009-10-01 00:00:00

abstract：:The virulence plasmids of Salmonella typhimurium and other invasive Salmonella serovars have long been associated with the ability of these bacteria to cause systemic infection beyond the intestines in orally inoculated animals. Genetic analysis of virulence genes on the high-molecular-weight plasmids has revealed tha...

journal_title：Infection and immunity

authors： Gulig PA,Doyle TJ

更新日期：1993-02-01 00:00:00

abstract：:Acute lethality was induced in rabbits by the sequential injection of Propionibacterium acnes and lipopolysaccharide (LPS). P. acnes induced the infiltration of inflammatory cells into the liver lobules during the early phase, and LPS in the late phase caused death in association with pathological changes mimicking he...

journal_title：Infection and immunity

authors： Ikeda N,Mukaida N,Kaneko S,Fujioka N,Su S,Nariuchi H,Unoura M,Harada K,Nakanuma Y,Kobayashi K

更新日期：1995-12-01 00:00:00

abstract：:The pattern of invasion of human hair in vitro by the dermatophyte Microsporum gypseum was studied by transmission and scanning electron microscopy. Mycelia that invaded the hair cortex through the edge of cuticles showed a flattened "frond" growth in contrast to the filamentous form seen on ordinary laboratory media....

journal_title：Infection and immunity

authors： Kanbe T,Tanaka K

更新日期：1982-11-01 00:00:00

abstract：:During the process of phagocytosis, human leukocytes emit a burst of luminescence which can be measured in a liquid scintillation spectrometer. The enzyme superoxide dismutase, which removes superoxide anions (O(2.)), inhibited this chemiluminescence by 70% at a concentration of 100 mug/ml. The enzyme did not inhibit ...

journal_title：Infection and immunity

authors： Webb LS,Keele BB Jr,Johnston RB Jr

更新日期：1974-06-01 00:00:00

abstract：:Sterile sonic-treated materials of pneumococci grown in media containing N-acetylmannosamine as the carbohydrate source were lethal for mice. Purification of the toxic factor led to its identification as the enzyme neuraminidase. ...

journal_title：Infection and immunity

authors： Kelly R,Greiff D

更新日期：1970-07-01 00:00:00

abstract：:Type III and type VI secretion systems (T3SSs and T6SSs, respectively) are critical virulence determinants in several Gram-negative pathogens. In Burkholderia pseudomallei, the T3SS-3 and T6SS-1 clusters have been implicated in bacterial virulence in mammalian hosts. We recently discovered a regulatory cascade that co...

journal_title：Infection and immunity

authors： Chen Y,Wong J,Sun GW,Liu Y,Tan GY,Gan YH

更新日期：2011-08-01 00:00:00