An enzyme histochemical study of large muscle fibres in the neonatal mouse.

Abstract:

:Small clusters of extra large muscle fibres were identified in hindlimb muscles of neonatal mice (strain C57BL/10ScSn). At two days of age they had a significantly greater cross-sectional area than their normal counterparts (P less than 0.01). Fibre typing methods (NADH-tetrazolium reductase, ATPase and phosphorylase) classified them as 2A fast oxidative glycolytic (FOG fibres). The activity of NADH-tetrazolium reductase and the lysosomal enzymes beta-glucuronidase, acid phosphatase and dipeptidyl peptidase II were all elevated in the large fibres. Microsomal aminopeptidase (mAPP), a membrane-bound enzyme, also showed increased activity. The fibres are probably the mouse equivalent of the Wohlfart B fibres of the human fetus, with which comparison is made.

journal_name

J Anat

journal_title

Journal of anatomy

authors

Christie KN,Stewart RJ,Bacciocchi G

subject

Has Abstract

pub_date

1990-06-01 00:00:00

pages

139-49

eissn

0021-8782

issn

1469-7580

journal_volume

170

pub_type

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