当前位置： SCI文献检索 > JOURNAL OF ETHNOPHARMACOLOGY期刊下所有文献 > Antiallergic effects of Scutellaria baicalensis on inflammation in vivo and in vitro.

Antiallergic effects of Scutellaria baicalensis on inflammation in vivo and in vitro.

Abstract：

ETHNOPHARMACOLOGICAL RELEVANCE:Scutellaria baicalensis (SB) is one of the most widely used medicinal herbs for the treatment of inflammation. In this study, we investigated the antiallergic effect of SB in vivo and in vitro. MATERIALS AND METHODS:Sprague-Dawley (SD) rats received intradermal injections of anti-DNP IgE at each of three dorsal skin sites. Forty-eight hours later, each rat received an injection of DNP-HSA in saline containing 4% Evans blue through the dorsal vein of the penis. One hour before injection, SB extract was administered orally. The dorsal skin of the rats was removed and the pigment area measured. In addition, rat peritoneal mast cells (RPMCs) were cultured and purified to investigate histamine release. In vitro, human mast cells (HMC-1) were pretreated with SB extract for 30min before stimulation with phorbol 12-myristate 13-acetate (PMA) plus A23187. The effects on pro-inflammatory cytokine expression and mitogen activated protein (MAP) kinase expression were investigated using TNF-α and IL-8 assays, and Western blotting analysis of HMC-1 cells. RESULTS AND CONCLUSIONS:SB treatment inhibited the passive cutaneous anaphylaxis reaction compared to the control group, and histamine release decreased significantly following treatment of RPMCs with SB. In HMC-1 cells, SB restored IL-8 and TNF-α expression and inhibited MAP kinase expression in compound 48/80-induced HMC-1 cells. These data suggest that SB may prove to be a useful anti-inflammatory agent through its downregulation of the expression of various inflammatory mediators.

journal_name

J Ethnopharmacol

journal_title

Journal of ethnopharmacology

authors

Jung HS,Kim MH,Gwak NG,Im YS,Lee KY,Sohn Y,Choi H,Yang WM

doi

10.1016/j.jep.2012.02.044

subject

Has Abstract

pub_date

2012-05-07 00:00:00

pages

345-9

issue

1

eissn

0378-8741

issn

1872-7573

pii

S0378-8741(12)00140-7

journal_volume

141

pub_type

杂志文章

相关文献

JOURNAL OF ETHNOPHARMACOLOGY文献大全
  • Flavonoids from Tilia americana with anxiolytic activity in plus-maze test.

    abstract：:The aerial parts of Tilia americana var. mexicana (Schltdl) Hardin (Tiliaceae) have been widely used in Mexican traditional medicine to relieve sleeplessness, headache, and nervous excitement. The anxiolytic effect of four extracts and several flavonoid fractions from the bracts of Tilia americana subsp.mexicana, var....

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2008.04.019

    authors： Herrera-Ruiz M,Román-Ramos R,Zamilpa A,Tortoriello J,Jiménez-Ferrer JE

    更新日期：2008-07-23 00:00:00

  • An ethnopharmacological survey of the traditional medicine utilized in the community of Porvenir, Bajo Paraguá Indian Reservation, Bolivia.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Porvenir is a semi-isolated Indian community in the Bajo Paraguá Indian Reservation in Bolivian Amazon, one of the two communities of people from the Guarasug'we indigenous nation now close to extinction. The aim of our study was the collection of data on the traditional medicine utilized...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2011.12.029

    authors： Hajdu Z,Hohmann J

    更新日期：2012-02-15 00:00:00

  • Anticancer medicinal plants used by Moroccan people: Ethnobotanical, preclinical, phytochemical and clinical evidence.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Cancer is a major health problem worldwide. Drugs' side effects and high cost of treatment remain the main limitations of conventional therapy. Nowadays, developing new therapeutic strategies is necessary. Therefore, medicinal plants can be used to promote novel, safe, and potent anticanc...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2020.113435

    authors： Alami Merrouni I,Elachouri M

    更新日期：2021-02-10 00:00:00

  • Toxicological screening of traditional medicine Laghupatha (Cissampelos pareira) in experimental animals.

    abstract：:Laghupatha (Cissampelos pareira) a important medicinal plant in Indian traditional system of medicine and is widely used in many countries by different tribal. Despite the wide use of Cissampelos pareira in folk medicine, no study has been published in the scientific literature about its toxicological profile. In pres...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2007.12.008

    authors： Amresh G,Singh PN,Rao CV

    更新日期：2008-03-28 00:00:00

  • 5α-reductase inhibition and hair growth promotion of some Thai plants traditionally used for hair treatment.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Many Thai traditional herbs have been used for hundreds of years for hair treatment and nourishment, including hair loss. However, scientific evidence about their mechanisms of action has not yet been elucidated. AIMS OF THE STUDY:The purpose of this research is to define the possible me...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2011.12.010

    authors： Kumar N,Rungseevijitprapa W,Narkkhong NA,Suttajit M,Chaiyasut C

    更新日期：2012-02-15 00:00:00

  • Effects of hydroxysafflor yellow A on the activity and mRNA expression of four CYP isozymes in rats.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:In traditional therapy with Chinese medicine, hydroxysafflor yellow A (HSYA), a main active component isolated from the dried flower of Carthamus tinctorius L., is the principal efficiency ingredient of Safflor Yellow Injection. Now HSYA has been demonstrated to have good pharmacological ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2013.12.025

    authors： Xu RA,Xu ZS,Ge RS

    更新日期：2014-02-12 00:00:00

  • Hallucinogenic plant use and related indigenous belief systems in the Ecuadorian Amazon.

    abstract：:This review article focuses on the on-going use of plant hallucinogens, especially various Banisteriopsis species, among contemporary aboriginal populations of Ecuador. It surveys the evidence of prehistoric ayahuasca use by interpretations of Ecuadorian archaeological remains, and surveys in detail the use and belief...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/0378-8741(79)90003-5

    authors： Naranjo P

    更新日期：1979-04-01 00:00:00

  • Evaluation of the diuretic activity in two Mexican medicinal species: Selaginella nothohybrida and Selaginella lepidophylla and its effects with ciclooxigenases inhibitors.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Doradilla is a plant that has a long history in the Mexican traditional system of medicine for gall and renal stones, diuresis, stomach and liver inflammation among other diseases. Major components isolated from these plants include biflavonoids as amentoflavone (1), robustaflavone (2) an...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2015.01.031

    authors： Aguilar MI,Benítez WV,Colín A,Bye R,Ríos-Gómez R,Calzada F

    更新日期：2015-04-02 00:00:00

  • Toxicity and potential anti-trypanosomal activity of ethanolic extract of Azadirachta indica (Maliacea) stem bark: an in vivo and in vitro approach using Trypanosoma brucei.

    abstract：AIM OF THE STUDY:To determine the toxicity and anti-trypanosomal activity of the ethanolic extract of Azadirachta indica (Maliacea) stem bark, through in vivo and in vitro approach using Trypanosoma brucei brucei. MATERIALS AND METHODS:Graded concentrations (100, 200, 400, 800, 1600 and 3200 mg/kg) of the crude stem b...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2010.01.013

    authors： Mbaya AW,Ibrahim UI,God OT,Ladi S

    更新日期：2010-03-24 00:00:00

  • Further studies on the antihepatotoxic activity of Phyllanthus maderaspatensis Linn.

    abstract：:Phyllanthus maderaspatensis (whole plant extracts) was evaluated for its antihepatotoxic and choleretic activities in rats. The plant extracts (200 mg/kg, n-hexane, ethyl alcohol or water) showed a remarkable hepatoprotective activity against acetaminophen-induced hepatotoxicity as judged from the serum marker enzymes...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2004.02.005

    authors： Asha VV,Akhila S,Wills PJ,Subramoniam A

    更新日期：2004-05-01 00:00:00

  • Neuroprotective effects of xiao-xu-ming decoction against ischemic neuronal injury in vivo and in vitro.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Xiao-Xu-Ming decoction (XXMD) has long been employed clinically to treat stroke in traditional Chinese Medicine. AIM OF THE STUDY:To investigate the neuroprotective effects of XXMD in vivo and in vitro stroke models and determine involved mechanisms. MATERIALS AND METHODS:Two models (fo...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2009.09.054

    authors： Zhu XH,Li SJ,Hu HH,Sun LR,Das M,Gao TM

    更新日期：2010-01-08 00:00:00

  • Screening of antiplasmodial properties among some traditionally used Iranian plants.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:An investigation of plants was undertaken through interviews and literature surveys on plants used to treat malaria or cancer or microbial diseases in Iran. AIM OF STUDY:In vitro and in vivo antiplasmodial tests were carried out on selected plants traditionally used in Iran. MATERIALS A...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2008.10.041

    authors： Esmaeili S,Naghibi F,Mosaddegh M,Sahranavard S,Ghafari S,Abdullah NR

    更新日期：2009-01-30 00:00:00

  • The scorpion in Spanish folk medicine: a review of traditional remedies for stings and its use as a therapeutic resource.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:While scorpionism is not a serious public health problem in Spain, traditional Spanish knowledge has retained a large number of plant-based and animal-based remedies for scorpion stings. Additionally, this arthropod plays an important role in the treatment of its own sting and has become ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jep.2012.12.033

    authors： González JA,Vallejo JR

    更新日期：2013-03-07 00:00:00

  • Studies on the toxicity of gambogic acid in rats.

    abstract：AIM:To study the chronic toxicity of gambogic acid (GA), the major active ingredient of gamboges, a brownish to orange resin extracted from the Garcinia hanburyi (family Guttiferae) in Southeast Asia, using Sprague-Dawley rat as an animal model and provide further theoretical support for clinical applications of this p...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2008.02.027

    authors： Qi Q,You Q,Gu H,Zhao L,Liu W,Lu N,Guo Q

    更新日期：2008-05-22 00:00:00

  • Gastrodia elata prevents huntingtin aggregations through activation of the adenosine A₂A receptor and ubiquitin proteasome system.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Gastrodia elata Blume (Fam. Orchidaceae) is a traditional Chinese herbal medicine for treating headaches, dizziness, tetanus, epilepsy, and numbness of the limbs, which suggests that it has neuroprotective effect. AIM OF THE STUDY:To validate the neuroprotection of Gastrodia elata in pre...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2011.08.075

    authors： Huang CL,Yang JM,Wang KC,Lee YC,Lin YL,Yang YC,Huang NK

    更新日期：2011-10-31 00:00:00

  • Phoradendron liga (Gill. ex H. et A.) Eichl. (Viscaceae) used in folk medicine: anatomical, phytochemical, and immunochemical studies.

    abstract：:Phoradendron liga (Gill. ex H. et A.) Eichl. is a Viscaceae widely distributed in Argentina. It has been commonly used in folk medicine as a substitute of the European mistletoe (Viscum album L.) to decrease high blood pressure due to their external similarity. In this study, the anatomical features as well as micromo...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2004.04.027

    authors： Varela BG,Fernández T,Ricco RA,Zolezzi PC,Hajos SE,Gurni AA,Alvarez E,Wagner ML

    更新日期：2004-09-01 00:00:00

  • Double-blind randomized placebo-controlled trial on efficacy and safety of Lactuca sativa L. seeds on pregnancy-related insomnia.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:There is limited evidence about the role of herbal and traditional medicine in pregnancy-related insomnia. Extant documents on traditional Persian medicine refer to many plants which could induce sleep and which were used by pregnant women. In Iran, local herbal shops continue to provide ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jep.2018.08.001

    authors： Pour ZS,Hosseinkhani A,Asadi N,Shahraki HR,Vafaei H,Kasraeian M,Bazrafshan K,Faraji A

    更新日期：2018-12-05 00:00:00

  • Biphasic effects of baicalin, an active constituent of Scutellaria baicalensis Georgi, in the spontaneous sleep-wake regulation.

    abstract：AIM OF THE STUDY:Baicalin is an active compound originating from the root of Scutellaria baicalensis Georgi, which has been used for anti-inflammation, anti-bacteria, anti-hypertension, anti-allergy and sedation since ancient China, though the neuronal mechanisms involved in the sedative effect is still unclear. Baical...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2011.03.023

    authors： Chang HH,Yi PL,Cheng CH,Lu CY,Hsiao YT,Tsai YF,Li CL,Chang FC

    更新日期：2011-05-17 00:00:00

  • Ethnobotanical survey and antibacterial activity of some plants used in Guinean traditional medicine.

    abstract：:A total of 418 healers have been interviewed in Guinea, a coastal country of West Africa, ranging between 7 degrees 30 and 12 degrees 30 of northern latitude and 8 degrees and 15 degrees of western longitude. Plant species used by the local inhabitants to treat infectious diseases were identified using ethnobotanical,...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2007.07.009

    authors： Magassouba FB,Diallo A,Kouyaté M,Mara F,Mara O,Bangoura O,Camara A,Traoré S,Diallo AK,Zaoro M,Lamah K,Diallo S,Camara G,Traoré S,Kéita A,Camara MK,Barry R,Kéita S,Oularé K,Barry MS,Donzo M,Camara K,Toté K,Be

    更新日期：2007-10-08 00:00:00

  • Hepatoprotective activity of flavonoids from Cichorium glandulosum seeds in vitro and in vivo carbon tetrachloride-induced hepatotoxicity.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Cichorium glandulosum Boiss. et Huet was used historically in Uyghur folk medicine. Its roots, seeds, and aerial parts are extensively used by Uyghur residents in Xinjiang to eliminate savda typhoid, dredge and cure obstructive jaundice variety liver disorders. AIM OF THE STUDY:To evalua...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2015.08.045

    authors： Tong J,Yao X,Zeng H,Zhou G,Chen Y,Ma B,Wang Y

    更新日期：2015-11-04 00:00:00

  • Ethnoveterinary practices of owners of pneumatic-cart pulling camels in Faisalabad City (Pakistan).

    abstract：:The present study was planned to investigate the ethnoveterinary methods practiced by the owners of pneumatic-cart pulling camels in Faisalabad Metropolis (Pakistan). During a 7-year-period (November 1992-November 1999), 200 owners of draught camels working in the city were interviewed. Information concerning the ethn...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2004.11.008

    authors： Muhammad G,Khan MZ,Hussain MH,Iqbal Z,Iqbal M,Athar M

    更新日期：2005-02-28 00:00:00

  • Lysosomal membrane stabilization and anti-inflammatory activity of Clerodendrum phlomidis L.f., a traditional medicinal plant.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Clerodendrum phlomidis L.f., is used to treat several inflammatory diseases and arthritis in Indian traditional system and folk medicine. AIM OF THE STUDY:The aim of the present study was to evaluate the scientific basis of antiinflammatory activity of different organic solvent extracts ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2011.04.028

    authors： Babu NP,Pandikumar P,Ignacimuthu S

    更新日期：2011-06-01 00:00:00

  • Immunomodulation of RAW264.7 macrophages by GLIS, a proteopolysaccharide from Ganoderma lucidum.

    abstract：:The immunomodulatory effect of Ganoderma lucidum immunomodulating substance (GLIS) on macrophages has been investigated as part of on-going research into the anti-cancer properties of Ganoderma lucidum. Proliferation of bone marrow macrophages (BMMs) was enhanced by GLIS in a dose-dependent manner. Microscopic examina...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2007.03.035

    authors： Ji Z,Tang Q,Zhang J,Yang Y,Jia W,Pan Y

    更新日期：2007-07-25 00:00:00

  • Effects of Red Ginseng extract on allergic reactions to food in Balb/c mice.

    abstract：AIM OF THE STUDY:Red Ginseng roots (Panax ginseng C.A. Meyer) have traditionally been thought to have anti-allergic effects, but their influence on food-induced allergic responses is unclear. MATERIALS AND METHODS:This study examined the effects of a Red Ginseng extract on an ova-albumin (OVA)-evoked allergic reaction...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2010.08.012

    authors： Sumiyoshi M,Sakanaka M,Kimura Y

    更新日期：2010-10-28 00:00:00

  • The aqueous extract of Terminalia superba (Combretaceae) prevents glucose-induced hypertension in rats.

    abstract：AIM OF THE STUDY:The stem bark of Terminalia superba (Combretaceae) (TS) is used in traditional Cameroonian medicine as antihypertensive remedy. The aim of this study was to investigate the hypotensive and the antihypertensive effects of the aqueous extract of the stem bark of Terminalia superba. MATERIALS AND METHODS...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2010.11.016

    authors： Tom EN,Demougeot C,Mtopi OB,Dimo T,Djomeni PD,Bilanda DC,Girard C,Berthelot A

    更新日期：2011-01-27 00:00:00

  • Cardiovascular and diuretic activity of kaurene derivatives of Xylopia aethiopica and Alepidea amatymbica.

    abstract：:The extractives, crude and pure, of Alepidea amatymbica (AA) and Xylopia aethiopica (XA) were subjected to bioassay-directed phytochemical examination for potential cardiovascular and diuretic activity. All extractives and derivatives (XA/O, AA/1, xylopic acid, AA/3, AA/4, AA/5, AA/6, XA/1, XA/2, XA/3) displayed low t...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/s0378-8741(01)00285-9

    authors： Somova LI,Shode FO,Moodley K,Govender Y

    更新日期：2001-10-01 00:00:00

  • Piper sarmentosum Roxb. produces antidepressant-like effects in rodents, associated with activation of the CREB-BDNF-ERK signaling pathway and reversal of HPA axis hyperactivity.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:There are many plants of genus Piper which have been reported to induce antidepressant-like effects, Piper sarmentosum (PS) is one of them. PS is a Chinese herbal medicine and a traditional edible vegetable. MATERIALS AND METHODS:In the present study, the antidepressant-like effects of P...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2017.01.037

    authors： Li Q,Qu FL,Gao Y,Jiang YP,Rahman K,Lee KH,Han T,Qin LP

    更新日期：2017-03-06 00:00:00

  • Chrysoeriol and other polyphenols from Tecoma stans with lipase inhibitory activity.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Tecoma stans is traditionally used by several ethnical groups in Mexico and Central America to treat diabetes. This species is mentioned in the majority of the ethnopharmacological studies compiled in Mexico focused in medicinal plants used as anti-diabetic treatment. AIM OF THE STUDY:Re...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2016.03.014

    authors： Ramirez G,Zamilpa A,Zavala M,Perez J,Morales D,Tortoriello J

    更新日期：2016-06-05 00:00:00

  • Selective inducible nitric oxide synthase suppression by new bracteanolides from Murdannia bracteata.

    abstract：:Murdannia bracteata has been used as a Taiwanese folk medicine for its anti-inflammatory properties. However, neither its active ingredients nor its anti-inflammatory actions are well defined. Nitric oxide (NO), overproduced by activated macrophages via inducible NO synthase (iNOS), is suggested to be a significant pa...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2007.02.025

    authors： Wang GJ,Chen SM,Chen WC,Chang YM,Lee TH

    更新日期：2007-06-13 00:00:00

  • Baitouweng decoction alleviates dextran sulfate sodium-induced ulcerative colitis by regulating intestinal microbiota and the IL-6/STAT3 signaling pathway.

    abstract：ETHNOPHARMACOLOGICAL RELEVANCE:Baitouweng (BTW) decoction, a Chinese traditional medicine prescription, has been used to treat ulcerative colitis (UC) over hundreds of years. In this study, we investigated the anti-inflammatory effects of BTW and intestinal flora of dextran sulfate sodium (DSS)-induced UC mice, and we ...

    journal_title：Journal of ethnopharmacology

    pub_type： 杂志文章

    doi：10.1016/j.jep.2020.113357

    authors： Xuan-Qing CHEN,Xiang-Yu LV,Shi-Jia LIU

    更新日期：2021-01-30 00:00:00