Characterization and comparison of Fumonisin B(1)-protein conjugates by six methods.

abstract：:Previous studies have shown that germin-like proteins (GLPs) are present ubiquitously in rice and Arabidopsis. However, the understanding regarding their role in development and abiotic/biotic stress resistance remains limited. In the present study, we report genome-wide identification, characterisation, subcellular l...

journal_title：International journal of molecular sciences

authors： Li L,Xu X,Chen C,Shen Z

更新日期：2016-09-23 00:00:00

abstract：:Hemorrhage is one of the most obvious pathological phenomena in grass carp reovirus (GCRV) infection. The etiology of GCRV-induced hemorrhage is unclear. We found inducible nitric oxide synthase (iNOS) may relate to viral hemorrhage according to the previous studies, which is expressed at high levels after GCRV infect...

journal_title：International journal of molecular sciences

authors： Liang B,Su J

更新日期：2019-12-16 00:00:00

abstract：:Antibiotics without selectivity for acne treatment may destroy the beneficial microbes in the human microbiome that helps to fight Cutibacterium acnes (C. acnes), a bacterium associated with inflammatory acne vulgaris. Probiotic treatment by direct application of live Staphylococcus epidermidis (S. epidermidis) onto t...

journal_title：International journal of molecular sciences

authors： Yang AJ,Marito S,Yang JJ,Keshari S,Chew CH,Chen CC,Huang CM

更新日期：2018-12-20 00:00:00

abstract：:Strigolactones (SLs), a group of plant hormones, induce germination of root-parasitic plants and inhibit shoot branching in many plants. Shoot branching is an important trait that affects the number and quality of flowers and fruits. Root-parasitic plants, such as Phelipanche spp., infect tomato roots and cause econom...

journal_title：International journal of molecular sciences

authors： Hasegawa S,Tsutsumi T,Fukushima S,Okabe Y,Saito J,Katayama M,Shindo M,Yamada Y,Shimomura K,Yoneyama K,Akiyama K,Aoki K,Ariizumi T,Ezura H,Yamaguchi S,Umehara M

更新日期：2018-09-06 00:00:00

abstract：:The development of stimulus-responsive photosensitizer delivery systems that carry a high payload of photosensitizers is of great importance in photodynamic therapy. In this study, redox-responsive polysilsesquioxane nanoparticles (PSilQNPs) built by a reverse microemulsion approach using 5,10,15,20-tetrakis(carboxyph...

journal_title：International journal of molecular sciences

authors： Vega DL,Lodge P,Vivero-Escoto JL

更新日期：2015-12-31 00:00:00

abstract：:Receptor targeted nuclear imaging directed against molecular markers overexpressed on breast cancer (BC) cells offers a sensitive and specific method for BC imaging. Currently, a few targets such as estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), somatostatin recept...

journal_title：International journal of molecular sciences

authors： Dalm SU,Verzijlbergen JF,De Jong M

更新日期：2017-01-26 00:00:00

abstract：:Chemerin, a novel adipokine, has been associated with metabolic, inflammatory, and atherosclerotic diseases. We aimed to determine the genetic basis of chemerin levels by conducting a genome-wide association study (GWAS) and to investigate the role of RARRES2 polymorphisms and circulating chemerin levels in the long-t...

journal_title：International journal of molecular sciences

authors： Er LK,Hsu LA,Juang JJ,Chiang FT,Teng MS,Tzeng IS,Wu S,Lin JF,Ko YL

更新日期：2019-03-07 00:00:00

abstract：:Forty mice were randomly divided into four groups on the basis of the diet to be fed as follows: 5% (low) fat diet (T1: LF); 20% (high) fat diet (T2: HF); 20% fat containing 1% conjugated linoleic acid (CLA) (T3: HFC); and 20% fat containing 1% CLA with 0.5% biopolymers (T4: HFCB). The high-fat with CLA diet groups (H...

journal_title：International journal of molecular sciences

authors： Hur SJ,Kim DH,Chun SC,Lee SK

更新日期：2013-03-26 00:00:00

abstract：:Cholangiocarcinoma (CCA) is the second most common type of liver cancer, and is highly aggressive with very poor prognosis. CCA is classified into intrahepatic cholangiocarcinoma (iCCA) and extra-hepatic cholangiocarcinoma (eCCA), which is further stratified into perihilar (pCCA) and distal (dCCA). Cancer stem cells (...

journal_title：International journal of molecular sciences

authors： Wu HJ,Chu PY

更新日期：2019-08-25 00:00:00

abstract：:Ovarian follicle steroidogenesis associated with embryo quality results in a successful pregnancy. Each follicle consists of an oocyte surrounded by granulosa cells, which secrete several steroid and peptide hormones. Follicles harvested from women who conceived after assisted reproductive therapy (ART) had significan...

journal_title：International journal of molecular sciences

authors： Sreerangaraja Urs DB,Wu WH,Komrskova K,Postlerova P,Lin YF,Tzeng CR,Kao SH

更新日期：2020-05-19 00:00:00

abstract：:The consumption of polyphenols has frequently been associated with low incidence of degenerative diseases. Most of these natural antioxidants come from fruits, vegetables, spices, grains and herbs. For this reason, there has been increasing interest in identifying plant extract compounds. Polymeric tannins and monomer...

journal_title：International journal of molecular sciences

authors： de la Luz Cádiz-Gurrea M,Fernández-Arroyo S,Segura-Carretero A

更新日期：2014-11-06 00:00:00

abstract：:At a resting sarcomere length of approximately 2.2 µm bony fish muscles put into rigor in the presence of BDM (2,3-butanedione monoxime) to reduce rigor tension generation show the normal arrangement of myosin head interactions with actin filaments as monitored by low-angle X-ray diffraction. However, if the muscles a...

journal_title：International journal of molecular sciences

authors： Eakins F,Harford JJ,Knupp C,Roessle M,Squire JM

更新日期：2018-07-18 00:00:00

abstract：:The aryl hydrocarbon receptor (AhR) is a ligand-dependent transcription factor that mediates the biological and toxicological effects of halogenated aromatic hydrocarbons, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). When activated by dioxin, the cytosolic AhR protein complex translocates into the nucleus and d...

journal_title：International journal of molecular sciences

authors： Li S,Pei X,Zhang W,Xie HQ,Zhao B

更新日期：2014-04-16 00:00:00

abstract：:Three kinds of new water-soluble polysaccharides (FA, FB and FC) were isolated from wild mushroom Agaricus bitorquis (Quél.) Sacc. Chaidam by the classical method "water extraction and alcohol precipitation" and purified by column chromatography. The Mw of FA, FB and FC ranged from 5690 Da to 38,340 Da. The three poly...

journal_title：International journal of molecular sciences

authors： Jiao Y,Kuang H,Wu J,Chen Q

更新日期：2019-02-01 00:00:00

abstract：:Cucumber green mottle mosaic virus (CGMMV) is a member of the genus Tobamovirus, which cause diseases in cucurbits, especially watermelon. In watermelon, symptoms develop on the whole plant, including leaves, stems, peduncles, and fruit. To better understand the molecular mechanisms of watermelon early responses to CG...

journal_title：International journal of molecular sciences

authors： Sun Y,Fan M,He Y

更新日期：2019-01-31 00:00:00

abstract：:Leuconostoc mesenteroides DRP105 isolated from Chinese sauerkraut juice is an intensive producer of dextran. We report the complete genome sequence of Leu. mesenteroides DRP105. This strain contains a dextransucrase gene (dsr) involved in the production of dextran, possibly composed of glucose monomers. To explore the...

journal_title：International journal of molecular sciences

authors： Du R,Zhou Z,Han Y

更新日期：2020-09-09 00:00:00

abstract：:(1) Background: TP53 deficiency remains a major adverse event in Multiple Myeloma (MM) despite therapeutic progresses. As it is not possible to target TP53 deficiency with pharmacological agents, we explored the possibility of activating another p53 family member, p73, which has not been well studied in myeloma. (2) M...

journal_title：International journal of molecular sciences

authors： Gillardin PS,Descamps G,Maiga S,Tessoulin B,Djamai H,Lucani B,Chiron D,Moreau P,Le Gouill S,Amiot M,Pellat-Deceunynck C,Moreau-Aubry A

更新日期：2017-12-23 00:00:00

abstract：:This review focuses on the role of 5'-activated protein kinase (AMPK) in the effects of resveratrol (RSV) and some RSV derivatives on hepatic steatosis. In vitro studies, performed in different hepatic cell models, have demonstrated that RSV is effective in preventing liver TG accumulation by activating AMPK, due to i...

journal_title：International journal of molecular sciences

authors： Trepiana J,Milton-Laskibar I,Gómez-Zorita S,Eseberri I,González M,Fernández-Quintela A,Portillo MP

更新日期：2018-11-05 00:00:00

abstract：:Ly-6/uPAR or three-finger proteins (TFPs) contain a disulfide-stabilized β-structural core and three protruding loops (fingers). In mammals, TFPs have been found in epithelium and the nervous, endocrine, reproductive, and immune systems. Here, using heteronuclear NMR, we determined the three-dimensional (3D) structure...

journal_title：International journal of molecular sciences

authors： Paramonov AS,Kocharovskaya MV,Tsarev AV,Kulbatskii DS,Loktyushov EV,Shulepko MA,Kirpichnikov MP,Lyukmanova EN,Shenkarev ZO

更新日期：2020-10-01 00:00:00

abstract：:Prion diseases are rare transmissible neurodegenerative disorders caused by the accumulation of a misfolded isoform (PrPSc) of the cellular prion protein (PrPC) in the central nervous system (CNS). Neuropathological hallmarks of prion diseases are neuronal loss, astrogliosis, and enhanced microglial proliferation and ...

journal_title：International journal of molecular sciences

authors： Peggion C,Stella R,Lorenzon P,Spisni E,Bertoli A,Massimino ML

更新日期：2020-10-20 00:00:00

abstract：:Transforming growth factor (TGF)-βs are pluripotent cytokines with stimulatory and inhibitory properties for multiple types of immune cells. Analyses of genetic knockouts of each isoform of TGF-β have revealed differing expression patterns and distinct roles for the three mammalian isoforms of TGF-β. Considerable effo...

journal_title：International journal of molecular sciences

authors： Komai T,Okamura T,Inoue M,Yamamoto K,Fujio K

更新日期：2018-08-01 00:00:00

abstract：:Bladder cancer is the second most common urological malignancy in the world. In 70% of cases it is initially diagnosed as non-muscle-invasive bladder cancer (NMIBC) and it is amenable to local treatments, with intravesical (IVES) Bacillus-Calmette-Guerin (BCG) immunotherapy being routinely used after transurethral res...

journal_title：International journal of molecular sciences

authors： Hojeij R,Domingos-Pereira S,Nkosi M,Gharbi D,Derré L,Schiller JT,Jichlinski P,Nardelli-Haefliger D

更新日期：2016-07-14 00:00:00

abstract：:Cypermethrin is one of the most highly effective synthetic pyrethroid insecticides. The toxicity of cypermethrin to the reproductive and nervous systems has been well studied. However, little is known about the toxic effect of cypermethrin on immune cells such as macrophages. Here, we investigated the cytotoxicity of ...

journal_title：International journal of molecular sciences

authors： Huang F,Liu Q,Xie S,Xu J,Huang B,Wu Y,Xia D

更新日期：2016-06-17 00:00:00

abstract：:Sjögren's syndrome (SS) is a chronic autoimmune disease characterized by lymphocytic infiltration of salivary and lacrimal glands resulting in diminished production of saliva and tears. The pathophysiology of SS has not yet been fully deciphered. Classically it has been postulated that sicca symptoms in SS patients ar...

journal_title：International journal of molecular sciences

authors： Soyfoo MS,Chivasso C,Perret J,Delporte C

更新日期：2018-10-30 00:00:00

abstract：:The renal cortex drives renal function. Hypoxia/reoxygenation are primary factors in ischemia-reperfusion (IR) injuries, but renal oxygenation per se is complex and awaits full elucidation. Few mathematical models address this issue: none captures cortical tissue heterogeneity. Using agent-based modeling, we develop t...

journal_title：International journal of molecular sciences

authors： Aubert V,Kaminski J,Guillaud F,Hauet T,Hannaert P

更新日期：2019-12-11 00:00:00

abstract：:Biofilms are a multicellular way of life, where bacterial cells are close together and embedded in a hydrated macromolecular matrix which offers a number of advantages to the cells. Extracellular polysaccharides play an important role in matrix setup and maintenance. A water-insoluble polysaccharide was isolated and p...

journal_title：International journal of molecular sciences

authors： Bellich B,Jou IA,Caterino M,Rizzo R,Ravenscroft N,Fazli M,Tolker-Nielsen T,Brady JW,Cescutti P

更新日期：2020-03-02 00:00:00

abstract：:Mechanistic approaches to modeling the effects of ionizing radiation on cells are on the rise, promising a better understanding of predictions and higher flexibility concerning conditions to be accounted for. In this work we modified and extended a previously published mechanistic model of cell survival after photon i...

journal_title：International journal of molecular sciences

authors： Liew H,Klein C,Zenke FT,Abdollahi A,Debus J,Dokic I,Mairani A

更新日期：2019-11-30 00:00:00

abstract：:Ramie (Boehmeria nivea L. Gaud), commonly known as China grass, is a perennial bast fiber plant of the Urticaceae. In China, ramie farming, industry, and trade provide income for about five million people. Drought stress severely affects ramie stem growth and causes a dramatic decrease in ramie fiber production. There...

journal_title：International journal of molecular sciences

authors： An X,Chen J,Zhang J,Liao Y,Dai L,Wang B,Liu L,Peng D

更新日期：2015-02-04 00:00:00

abstract：:Little is known about the interactions of single nucleotide polymorphisms (SNPs) and overweight/obesity on blood pressure levels. The present study was undertaken to detect 10 lipid-related gene SNPs and their interactions with overweight/obesity on blood pressure levels. Genotyping of ATP-binding cassette transporter...

journal_title：International journal of molecular sciences

authors： Yin RX,Wu DF,Aung LH,Yan TT,Cao XL,Long XJ,Miao L,Liu WY,Zhang L,Li M

更新日期：2012-01-01 00:00:00

abstract：:The Duchenne muscular dystrophy (DMD) gene has a complex expression pattern regulated by multiple tissue-specific promoters and by alternative splicing (AS) of the resulting transcripts. Here, we used an RNAi-based approach coupled with DMD-targeted RNA-seq to identify RNA-binding proteins (RBPs) that regulate splicin...

journal_title：International journal of molecular sciences

authors： Miro J,Bougé AL,Murauer E,Beyne E,Da Cunha D,Claustres M,Koenig M,Tuffery-Giraud S

更新日期：2020-10-21 00:00:00