Distribution of vasoactive intestinal peptide, pituitary adenylate cyclase-activating peptide, nitric oxide synthase, and their receptors in human and rat sphenopalatine ganglion.

abstract：:I.c.v. injection of L-ornithine has been shown to have sedative and hypnotic effects on neonatal chicks exposed to acute stressful conditions. To clarify the mechanism, we conducted three experiments under strengthened stressful conditions with corticotropin-releasing factor (CRF). In Experiment 1, the effect of i.c.v...

journal_title：Neuroscience

authors： Kurata K,Shigemi K,Tomonaga S,Aoki M,Morishita K,Denbow DM,Furuse M

更新日期：2011-01-13 00:00:00

abstract：:Obesity may result from dysfunction of the reward system, especially in the nucleus accumbens (Acb). Based on this hypothesis, many researchers have tested the effect of high-frequency stimulation (HFS) of the Acb shell (Acb-Sh) and/or core (Acb-Co) on ingestive behaviors, but few studies have explored the possible me...

journal_title：Neuroscience

authors： Wei N,Wang Y,Wang X,He Z,Zhang M,Zhang X,Pan Y,Zhang J,Qin Z,Zhang K

更新日期：2015-08-20 00:00:00

abstract：:N-Methyl-D-aspartate receptors are fundamental for neuronal plasticity and development in the CNS. Most studies have examined postsynaptic roles of this receptor, but there are also indications for a presynaptic location and function. Here, we provide electrophysiological evidence for the existence of presynaptic N-me...

journal_title：Neuroscience

authors： Berretta N,Jones RS

更新日期：1996-11-01 00:00:00

abstract：:Electrical stimulation of the distal stump of cut peripheral nerves is a commonly accepted way to evoke neurogenic inflammation. Nevertheless, the modulatory effect of biogenic amines and vasoactive peptides released from efferent fibres can be excluded only if the dorsal roots are stimulated. The present study was fo...

journal_title：Neuroscience

authors： Pintér E,Szolcsányi J

更新日期：1995-09-01 00:00:00

abstract：:Necrostatin-1 (Nec-1) is an inhibitor of necroptosis, playing an important role in inhibition of pathological death in the central nervous system (CNS). Our earlier study suggests that Nec-1 protects the injured spinal cord. In this study, we found that Nec-1 reduces the elevated Ca(2+) concentration in mitochondria p...

journal_title：Neuroscience

authors： Wang Y,Wang J,Yang H,Zhou J,Feng X,Wang H,Tao Y

更新日期：2015-03-19 00:00:00

abstract：:In an attempt to evaluate the cellular organization and efferent projections of the nucleus tegmenti pedunculopontinus pars compacta, several experiments were performed in the rat. From measurements of neurons in the nucleus tegmenti pedunculopontinus pars compacta in Nissl-stained sections, the nucleus was observed t...

journal_title：Neuroscience

authors： Sugimoto T,Hattori T

更新日期：1984-04-01 00:00:00

abstract：:The presence of subgroups in vomeronasal sensory neurons has been known in various animals. To elucidate possible functional subdivisions in the guinea-pig accessory olfactory bulb, the combined studies with GTP-binding protein immunohistochemistry, electrophysiological and optical recordings were carried out. Gi2 alp...

journal_title：Neuroscience

authors： Sugai T,Sugitani M,Onoda N

更新日期：1997-08-01 00:00:00

abstract：:Interleukin-1 (IL-1) plays a crucial role in stress responses and its mRNA is induced in the brain by stress load; however, the precise role of IL-1 in higher brain functions and their abnormalities is largely unknown. Here, we report that IL-1 receptor antagonist (IL-1Ra) knockout (KO) mice, which lack IL-1Ra molecul...

journal_title：Neuroscience

authors： Wakabayashi C,Kiyama Y,Kunugi H,Manabe T,Iwakura Y

更新日期：2011-09-29 00:00:00

abstract：:Nociceptin/orphanin FQ (N/OFQ) is an opioid-related peptide that stimulates corticosterone release after i.c.v. administration in non-stressed rats. We employed in situ hybridization histochemistry to investigate N/OFQ-stimulated activation of the HPA axis at the hypothalamic and pituitary level. We have demonstrated ...

journal_title：Neuroscience

authors： Leggett JD,Harbuz MS,Jessop DS,Fulford AJ

更新日期：2006-09-15 00:00:00

abstract：:Transplantation of embryonic dopaminergic neurons is an experimental therapy for Parkinson's disease, but limited tissue availability and suboptimal survival of grafted dopaminergic neurons impede more widespread clinical application. Glial cell line-derived neurotrophic factor (GDNF) and neurotrophin-4/5 (NT-4/5) exe...

journal_title：Neuroscience

authors： Meyer M,Matarredona ER,Seiler RW,Zimmer J,Widmer HR

更新日期：2001-01-01 00:00:00

abstract：:Noninvasive functional imaging holds great promise for the future of translational research, due to the ability to directly compare between preclinical and clinical models of psychiatric disorders. Despite this potential, concerns have been raised regarding the necessity to anesthetize rodent and monkey subjects durin...

journal_title：Neuroscience

authors： Smith ML,Li J,Cote DM,Ryabinin AE

更新日期：2016-03-01 00:00:00

abstract：:Previous studies in our laboratories found that isolectin B(4)(IB(4))-positive polymodal nociceptors in the mouse do not express transient receptor potential vanilloid 1 (TRPV1), nor does deletion of TRPV1 compromise the ability of these afferents to detect thermal stimuli. Considering that IB(4)-positive afferents ac...

journal_title：Neuroscience

authors： Christianson JA,McIlwrath SL,Koerber HR,Davis BM

更新日期：2006-06-19 00:00:00

abstract：:Brain connectivity studies have reported that functional networks change with older age. We aim to (1) investigate whether electroencephalography (EEG) data can be used to distinguish between individual functional networks of young and old adults; and (2) identify the functional connections that contribute to this cla...

journal_title：Neuroscience

authors： Moezzi B,Pratti LM,Hordacre B,Graetz L,Berryman C,Lavrencic LM,Ridding MC,Keage HAD,McDonnell MD,Goldsworthy MR

更新日期：2019-12-01 00:00:00

abstract：:The aim of this study was to assess the effect of blocking the axonal transport of sensory neuropeptides, by local injection of colchicine at pelvic ganglia level, on the sensory and efferent functions mediated by capsaicin-sensitive primary afferent neurons innervating the rat urinary bladder. Bilateral injection of ...

journal_title：Neuroscience

authors： Lecci A,Patacchini R,De Giorgio R,Corinaldesi R,Theodorsson E,Giuliani S,Santicioli P,Maggi CA

更新日期：1996-03-01 00:00:00

abstract：:In vivo cyclic adenosine monophosphate (cAMP)-induced N-methyl-D-aspartate receptor and mitogen-activated protein kinase activation was investigated in the dorsal striatum by semiquantitative immunocytochemistry. Intracerebroventricular infusion of 8-bromo-adenosine 3',5'-cyclic monophosphorothioate, Sp isomer (Sp-8-B...

journal_title：Neuroscience

authors： Choe ES,McGinty JF

更新日期：2000-01-01 00:00:00

abstract：:Neuronal nitric oxide synthase and haem oxygenase-2 are postulated to be important enzymes involved in neuronal transmission and modulation of free radical levels in neurons. Hippocampal and cortical neuronal nitric oxide synthase and haem oxygenase-2 expressions were compared in young adult (6 months) and aged (24-26...

journal_title：Neuroscience

authors： Law A,Doré S,Blackshaw S,Gauthier S,Quirion R

更新日期：2000-01-01 00:00:00

abstract：:The present study was designed to elucidate the distribution, time-course and mechanism(s) of status epilepticus-induced neuronal damage in the rat amygdaloid complex. Status epilepticus was induced with kainate (9 mg/kg, i.p.), and the behavioral and electrographic seizure activity of each rat was monitored via corti...

journal_title：Neuroscience

authors： Tuunanen J,Lukasiuk K,Halonen T,Pitkänen A

更新日期：1999-01-01 00:00:00

abstract：:We have recently shown that the phorbol ester 12-O-tetradecanoyl-phorbol-13-acetate enhances the depolarization induced, calcium dependent release of [3H]dopamine from cultured brain neurons in the rat. In the present study the effects of 12-O-tetradecanoyl-phorbol-13-acetate on the kinetic parameters of depolarizatio...

journal_title：Neuroscience

authors： Zurgil N,Yarom M,Zisapel N

更新日期：1986-12-01 00:00:00

abstract：:Certain patterns of neural activity can induce N-methyl-D-aspartic acid receptor (NMDAR)-dependent synaptic plasticity, one of the important foundations of memory. Here, we report that a patterned high-frequency stimulation (PHS) induces rat hippocampal long-term depression (LTD) in an NMDAR-independent manner that re...

journal_title：Neuroscience

authors： Zhu YY,Jing L,Duan TT,Yuan Q,Cao J,Zhou QX,Xu L

更新日期：2013-10-10 00:00:00

abstract：:Neuromedin U is a newly described regulatory peptide, found by radioimmunoassay in significant concentrations in both the brain and gut of the rat. The aim of the present study was to localize this peptide immunoreactivity to discrete structures of the gut and brain and to map its distribution using immunocytochemistr...

journal_title：Neuroscience

authors： Ballesta J,Carlei F,Bishop AE,Steel JH,Gibson SJ,Fahey M,Hennessey R,Domin J,Bloom SR,Polak JM

更新日期：1988-06-01 00:00:00

abstract：:A single session of aerobic exercise may offer one means to "prime" motor regions to be more receptive to the acquisition of a motor skill; however, the mechanisms whereby this priming may occur are not clear. One possible explanation may be related to the post-translational modification of plasticity-related receptor...

journal_title：Neuroscience

authors： Thacker JS,Xu Y,Tang C,Tupling AR,Staines WR,Mielke JG

更新日期：2019-08-01 00:00:00

abstract：:Environmental enrichment of laboratory animals leads to multi-faceted changes to physiology, health and disease prognosis. An important and under-appreciated factor in enhancing cognition through environmental manipulation may be improved basic sensory function. Previous studies have highlighted changes in cortical se...

journal_title：Neuroscience

authors： Devonshire IM,Dommett EJ,Grandy TH,Halliday AC,Greenfield SA

更新日期：2010-10-13 00:00:00

abstract：:A combined Golgi-electron microscope method was used to study the ultrastructural maturation of synapses on identified pyramidal and multipolar non-pyramidal neurons in the visual cortex of young and adult rabbits. In samples of 10 (time of eye opening), 14, 20 day old and 7 month old animals, fully impregnated pyrami...

journal_title：Neuroscience

authors： Müller LJ,Pattiselanno A,Nunes Cardozo B,Vrensen G

更新日期：1984-08-01 00:00:00

abstract：:This report presents the major structural features of neurons and their afferent input in nucleus magnocellularis, the avian homologue of the mammalian anteroventral cochlear nucleus. Results of light-microscope observations, as seen in Golgi, Nissl, and normal fiber preparations, as well as ultrastructural morphology...

journal_title：Neuroscience

authors： Jhaveri S,Morest DK

更新日期：1982-04-01 00:00:00

abstract：:P2X receptor-mediated responses to the ATP analogue, alpha,beta-methylene ATP, in rat brain cannot be accounted for by the receptor proteins known to be present. Such experiments are often performed on cells from neonates and, since differential developmental regulation of P2X1 and P2X2 receptor messenger RNAs has alr...

journal_title：Neuroscience

authors： Kidd EJ,Miller KJ,Sansum AJ,Humphrey PP

更新日期：1998-12-01 00:00:00

abstract：:Using microdialysis from medial prefrontal cortex of gerbils during aversive auditory conditioning in the shuttle-box we have previously shown a transient increase of dopamine efflux correlated with the establishment of avoidance behavior. We hypothesized that the acquisition of a new behavioral strategy is generally ...

journal_title：Neuroscience

authors： Stark H,Rothe T,Wagner T,Scheich H

更新日期：2004-01-01 00:00:00

abstract：:Both [3H]clonidine and [3H]idazoxan bind to alpha 2 adrenoceptors. The former also labels imidazoline receptors, and the latter non-adrenergic idazoxan binding sites. In order to investigate whether the imidazoline receptors and non-adrenergic idazoxan binding sites are identical, we compared the binding characteristi...

journal_title：Neuroscience

authors： De Vos H,Bricca G,De Keyser J,De Backer JP,Bousquet P,Vauquelin G

更新日期：1994-04-01 00:00:00

abstract：:Microelectrode recordings were made from 5-10 micron dia axons of adult rat spinal cord in vitro. Action potentials in response to electrical stimulation were recorded intracellularly and electrical characteristics of the axons were examined by injecting current pulses through a bridge circuit. All action potentials l...

journal_title：Neuroscience

authors： Blight AR,Someya S

更新日期：1985-05-01 00:00:00

abstract：:Theta frequency oscillation of the septo-hippocampal system has been considered as a prominent activity associated with cognitive function and affective processes. It is well documented that anxiolytic drugs diminish septo-hippocampal oscillatory Theta activity contributing to their either therapeutic or unwanted side...

journal_title：Neuroscience

authors： Hajós M,Hoffmann WE,Orbán G,Kiss T,Erdi P

更新日期：2004-01-01 00:00:00

abstract：:The 5-HT(6) receptor is predominantly expressed in the CNS and has been implicated in the regulation of cognitive function. Antagonists of the 5-HT(6) receptor improve cognitive performance in a number of preclinical models and have recently been found to be effective in Alzheimer's disease patients. Systemic administ...

journal_title：Neuroscience

authors： West PJ,Marcy VR,Marino MJ,Schaffhauser H

更新日期：2009-12-01 00:00:00