Alteration of expression levels of neuronal nitric oxide synthase and haem oxygenase-2 messenger RNA in the hippocampi and cortices of young adult and aged cognitively unimpaired and impaired Long-Evans rats.

abstract：:Extracellular single-unit recording methods were used to study the activity of neurons within a restricted portion of the dorsolateral mesopontine reticular formation, an area which includes the parabrachial, pedunculopontine tegmental and cuneiform nuclei. Recordings were obtained during presentations of unfamiliar a...

journal_title：Neuroscience

authors： Pascoe JP,Kapp BS

更新日期：1993-06-01 00:00:00

abstract：:Acute stress is known to evoke a discrete pattern of c-fos expression in the brain. The work reported here shows that this pattern is modified in regionally specific ways following repeated stress, and that this can be correlated with changes in telemetered heart rate, core temperature and corticosterone output that o...

journal_title：Neuroscience

authors： Chen X,Herbert J

更新日期：1995-02-01 00:00:00

abstract：:Brain injury is associated with neuroinflammation, and microglia are key players in this process. Microglia can acquire pro-inflammatory or anti-inflammatory properties, but how this affects neural stem cells (NSCs) remains controversial. Here, NSCs were grown in conditioned media collected from either non-stimulated ...

journal_title：Neuroscience

authors： Osman AM,Rodhe J,Shen X,Dominguez CA,Joseph B,Blomgren K

更新日期：2019-05-01 00:00:00

abstract：:A wide variety of species are used for the study of visual neuroscience. This is beneficial because fundamental mechanisms and theoretical principles of vision are likely to be highly conserved, while different species exhibit different visual capacities and present different technical advantages for experiments. Eigh...

journal_title：Neuroscience

authors： Reinagel P

更新日期：2015-06-18 00:00:00

abstract：:Nicotinic acetylcholine receptors (nAChRs) produce widespread and complex effects on neocortex excitability. We studied how heteromeric nAChRs regulate inhibitory post-synaptic currents (IPSCs), in fast-spiking (FS) layer V neurons of the mouse frontal area 2 (Fr2). In the presence of blockers of ionotropic glutamate ...

journal_title：Neuroscience

authors： Aracri P,Meneghini S,Coatti A,Amadeo A,Becchetti A

更新日期：2017-01-06 00:00:00

abstract：:Cholinergic neurons of the striatum play a crucial role in controlling output from this region. Their firing is under the control of a relatively limited glutamatergic input, deriving principally from the thalamus. Glutamate transmission is effected via three major subtypes of receptors, including those with affinity ...

journal_title：Neuroscience

authors： Bloomfield C,O'Donnell P,French SJ,Totterdell S

更新日期：2007-12-12 00:00:00

abstract：:The primary aim of this study was to investigate the effect of different training types and secondary to test gender differences on the training-related cortical plasticity induced by three different tongue-training paradigms: (1) therapeutic tongue exercises (TTE), (2) playing computer games with the tongue using the...

journal_title：Neuroscience

authors： Kothari M,Svensson P,Jensen J,Kjærsgaard A,Jeonghee K,Nielsen JF,Ghovanloo M,Baad-Hansen L

更新日期：2013-08-29 00:00:00

abstract：:We have shown that cortical acetylcholine modulates the balance between excitation and inhibition evoked in layer 5 pyramidal neurons of rat visual cortex [Lucas-Meunier E, Monier C, Amar M, Baux G, Frégnac Y, Fossier P (2009) Cereb Cortex 19:2411-2427]. Our aim is now to establish a functional basis for the role of t...

journal_title：Neuroscience

authors： Amar M,Lucas-Meunier E,Baux G,Fossier P

更新日期：2010-09-15 00:00:00

abstract：:Prenatal exposures to a variety of infections have been associated with an increased incidence of schizophrenia. We have reported that a single injection of the synthetic cytokine releaser PolyI:C to pregnant mice produced offspring that exhibited multiple schizophrenia-related behavioral deficits in adulthood. Here, ...

journal_title：Neuroscience

authors： Nyffeler M,Meyer U,Yee BK,Feldon J,Knuesel I

更新日期：2006-11-17 00:00:00

abstract：:The reciprocal connections between the mediodorsal thalamic nucleus and the prefrontal cortex participate in a circuit that is essential to a number of higher cognitive processes. Projections from the dopamine-containing cells of the ventral mesencephalon to the prefrontal cortex are also critical for these cognitive ...

journal_title：Neuroscience

authors： Melchitzky DS,Lewis DA

更新日期：2001-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is characterized by selective vulnerability of specific neuronal populations within particular brain regions. For example, hippocampal glutamatergic cell populations within the CA1/subicular pyramidal cell fields have been found to be particularly vulnerable early in AD progression. In contras...

journal_title：Neuroscience

authors： Rissman RA,Mishizen-Eberz AJ,Carter TL,Wolfe BB,De Blas AL,Miralles CP,Ikonomovic MD,Armstrong DM

更新日期：2003-01-01 00:00:00

abstract：:Synapse or dendritic spine loss is the strongest correlate of cognitive decline in Alzheimer's disease (AD), and neurofibrillary tangles (NFTs), but not amyloid-β plaques, associate more closely with transition to mild cognitive impairment. Yet, how dendritic spine architecture is affected by hyperphosphorylated tau i...

journal_title：Neuroscience

authors： Walker CK,Greathouse KM,Boros BD,Poovey EH,Clearman KR,Ramdas R,Muhammad HM,Herskowitz JH

更新日期：2020-12-17 00:00:00

abstract：:The ventral tegmental area of the rat brain has been shown to possess high densities of neurotensin- and dopamine-containing neuronal perikarya. We recently demonstrated that microinjection of neurotensin into the ventral tegmental area produces behavioral hyperactivity similar to amphetamine-induced increase in explo...

journal_title：Neuroscience

authors： Kalivas PW,Burgess SK,Nemeroff CB,Prange AJ Jr

更新日期：1983-03-01 00:00:00

abstract：:The inferior colliculus (IC) integrates ascending auditory input from the lower brainstem and descending input from the auditory cortex. Understanding how IC cells integrate these inputs requires identification of their synaptic arrangements. We describe excitatory synapses in the dorsal cortex, central nucleus, and l...

journal_title：Neuroscience

authors： Nakamoto KT,Mellott JG,Killius J,Storey-Workley ME,Sowick CS,Schofield BR

更新日期：2013-05-01 00:00:00

abstract：:Repetitive transcranial magnetic stimulation (rTMS) is an established technique that can modulate excitability of the motor cortex and corticospinal tract, beyond the duration of the stimulation itself. More recently, a newer repetitive technique, known as I-wave periodicity TMS (iTMS) has been purported to show incre...

journal_title：Neuroscience

authors： Kidgell DJ,Mason J,Frazer A,Pearce AJ

更新日期：2016-05-13 00:00:00

abstract：:Some studies have demonstrated that aging is associated with impaired vestibular reflexes, especially otolithic reflexes, resulting in postural instability. However, the neurochemical basis of these age-related changes is still poorly understood. The l-arginine metabolic system has been implicated in changes in the br...

journal_title：Neuroscience

authors： Liu P,Gupta N,Jing Y,Collie ND,Zhang H,Smith PF

更新日期：2017-04-21 00:00:00

abstract：:GABA(A) functioning has been implicated in anxiety and depressive disorders. In this regard, we suggested that in addition to analyzing GABA(A) and the subunits that comprise the GABA(A) receptor, it might be profitable to assess the coordinated expression of subunits that comprise the GABA(A) receptor cassette. We de...

journal_title：Neuroscience

authors： Poulter MO,Du L,Zhurov V,Merali Z,Anisman H

更新日期：2010-02-17 00:00:00

abstract：:A systematic line-sampling method is described for counting and mapping myelinated axons in transverse sections of the spinal cord. Its advantages over random sampling of small areas are considered. The technique was applied to quantifying experimental weight-drop contusion injuries of cat spinal cord, from several mo...

journal_title：Neuroscience

authors： Blight AR

更新日期：1983-10-01 00:00:00

abstract：:Repeated exposure to the psychostimulant drug, amphetamine, results in a persistent increase in the ability of the drug to elicit behavioral activation.(14,19) The development of sensitized responses to amphetamine involves long-lasting neuroadaptations within defined circuitry.(3,6,12,15,23) The behavioral expression...

journal_title：Neuroscience

authors： Arvanitogiannis A,Sullivan J,Amir S

更新日期：2000-01-01 00:00:00

abstract：:This study was performed using intracellular and multiunit extracellular recording techniques in order to characterize the role of nitric oxide in the afferent synaptic transmission of the vestibular system of the axolotl (Ambystoma tigrinum). Bath application of nitric oxide synthase inhibitors N(G)-nitro-L-arginine ...

journal_title：Neuroscience

authors： Flores A,Soto E,Vega R

更新日期：2001-01-01 00:00:00

abstract：:We have raised antisera against the GABA analogues gamma-vinyl GABA, diaminobutyric acid and gabaculine. These analogues are thought to be substrates for high-affinity GABA transporters. Retinae were exposed to micromolar concentrations of these analogues in the presence or absence of uptake inhibitors and then fixed ...

journal_title：Neuroscience

authors： Pow DV,Baldridge W,Crook DK

更新日期：1996-08-01 00:00:00

abstract：:Some of the myelinated axons in rat peripheral nerves possess marked axoplasmic carbonic anhydrase activity [Riley, Ellis and Bain (1982) J. Histochem. Cytochem. 30, 1275-1288; Riley and Lang (1984) J. Hand Surg. 9A, 112-120]. A mixture of reactive and nonreactive neurons was a general observation in cervical, thoraci...

journal_title：Neuroscience

authors： Riley DA,Ellis S,Bain JL

更新日期：1984-09-01 00:00:00

abstract：:Spatial memory retrieval and hippocampal long-term potentiation (LTP) are impaired by stress. KCNQ/Kv7 channels are closely associated with memory and the KCNQ/Kv7 channel activator flupirtine represents neuroprotective effects. This study aims to test whether KCNQ/Kv7 channel activation prevents acute stress-induced ...

journal_title：Neuroscience

authors： Li C,Huang P,Lu Q,Zhou M,Guo L,Xu X

更新日期：2014-11-07 00:00:00

abstract：:The electrical activity of locus coeruleus neurons was investigated during cortical spreading depression in urethane-anaesthetized rats. Cortical spreading depression was induced by a direct application of 1-3 M KCl solution to the surface of the cerebral cortex. The occurrence of cortical spreading depression was ass...

journal_title：Neuroscience

authors： Arakawa S,Nakamura S,Kawashima N,Nishiike S,Fujii Y

更新日期：1997-06-01 00:00:00

abstract：:Previous studies have identified the ventral and dorsal brain regions that respectively support semantic and non-semantic phonological access. Nevertheless, the specific role of the left occipitotemporal cortex (lOTC) in the two pathways of phonological access is ambiguous. To address that question, the present study ...

journal_title：Neuroscience

authors： Dong J,Lu C,Chen C,Li H,Liu X,Mei L

更新日期：2020-03-15 00:00:00

abstract：:Paclitaxel is one of the most commonly used anti-neoplastic drugs for the treatment of solid tumors. Unfortunately, its use is often associated with dose-limiting painful peripheral neuropathy and subsequent neuropathic pain that is resistant to standard analgesics. However, there are few clinically available drugs or...

journal_title：Neuroscience

authors： Kiya T,Kawamata T,Namiki A,Yamakage M

更新日期：2011-02-03 00:00:00

abstract：:Both long-term depression and long-term potentiation have been described at corticostriatal synapses. These long-lasting changes in synaptic strength were classically induced by high-frequency (100 Hz) electrical stimulations of cortical afferents. The purpose of the present study was to test the ability of corticostr...

journal_title：Neuroscience

authors： Charpier S,Mahon S,Deniau JM

更新日期：1999-01-01 00:00:00

abstract：:Estrogen (E) treatment of ovariectomized animals increases dendritic spines and/or synaptic protein expression in the hippocampus of female rats [J Neurosci 12 (1992) 2549; Endocrinology 142 (2001) 1284; Endocrinol Rev 20 (1999) 279; Annu Rev Pharmacol Toxicol 41 (2001) 569], mice [Proc Natl Acad Sci USA 101 (2004) 21...

journal_title：Neuroscience

authors： Lee SJ,Romeo RD,Svenningsson P,Campomanes CR,Allen PB,Greengard P,McEwen BS

更新日期：2004-01-01 00:00:00

abstract：:We have shown that transgenic transient axonal glycoprotein (TAG)/F3 mice, in which the mouse axonal glycoprotein F3/contactin was misexpressed from a regulatory region of the gene encoding the transient axonal glycoprotein TAG-1, exhibit a transient disruption of cerebellar granule and Purkinje cell development [Deve...

journal_title：Neuroscience

authors： Coluccia A,Tattoli M,Bizzoca A,Arbia S,Lorusso L,De Benedictis L,Buttiglione M,Cuomo V,Furley A,Gennarini G,Cagiano R

更新日期：2004-01-01 00:00:00

abstract：:Oxidative stress is believed to be a major factor for the onset of Parkinson's disease (PD). In this study, we have investigated oxidative status in transgenic Drosophila model of PD. Our results revealed elevated levels of reactive oxygen species (ROS) and lipid peroxidation (LPO) in A30P and A53T α-synuclein PD mode...

journal_title：Neuroscience

authors： Jahromi SR,Haddadi M,Shivanandappa T,Ramesh SR

更新日期：2015-05-07 00:00:00