Low-dose topiramate plus sodium divalproate for positive responders intolerant to full-dose monotherapy.

abstract：PURPOSE:Migraine is an exclusively human chronic disorder with ictal manifestations characterized by a multifaceted clinical complexity pointing to a cerebral cortical involvement. The present review is aimed to cover the clinical, neuroimaging, and neurophysiological literature on the role of the cerebral cortex in mi...

journal_title：Headache

authors： Barbanti P,Brighina F,Egeo G,Di Stefano V,Silvestro M,Russo A

更新日期：2020-10-01 00:00:00

abstract：:We present a patient with treatment refractory short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) who was found to have low levels of serum testosterone supporting the hypothalamic connection to this trigeminal autonomic cephalalgia. Clomiphene citrate therapy induce...

journal_title：Headache

authors： Rozen TD,Saper JR,Sheftell FD,Dodick DW

更新日期：2005-06-01 00:00:00

abstract：:The combination of lysine acetylsalicylate and metoclopramide is effective in the treatment of migraine attacks. It was unknown whether repeated doses could improve efficacy. The aim of this open trial was to evaluate the effects of a second, and eventually a third dose of lysine acetylsalicylate and metoclopramide wh...

journal_title：Headache

authors： Hugues FC,Lacoste JP,Danchot J,Joire JE

更新日期：1997-07-01 00:00:00

abstract：:Temporal arteritis is a form of systemic vasculitis that involves branches of the carotid artery. Clinical features are headache, visual loss, ophthalmoplegia, jaw claudication, temporal headache, with tenderness and thickening on the affected temporal artery. We present 3 cases of tongue necrosis due to this granulom...

journal_title：Headache

authors： Goicochea M,Correale J,Bonamico L,Dominguez R,Bagg E,Famulari A,Ameriso S,Sevlever G

更新日期：2007-09-01 00:00:00

abstract：:It has been suggested that magnesium (Mg) may play a role in the pathogenesis of headaches. Serum and intracellular measurements of Mg in headache patients have produced inconsistent results. The recent development of an ion-selective electrode for Mg2+ allowed precise measurement of serum ionized magnesium (IMg2+) in...

journal_title：Headache

authors： Mauskop A,Altura BT,Cracco RQ,Altura BM

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:It is generally felt that patient education and patient knowledge regarding triptan use for acute migraine management are important for successful and safe treatment. It is unclear how knowledgeable triptan users are regarding their triptan, how much education occurs when triptans are prescribed, and the imp...

journal_title：Headache

authors： Baron EP,Markowitz SY,Lettich A,Hastriter E,Lovell B,Kalidas K,Dodick DW,Schwedt TJ,American Headache Society Headache Fellows Research Consortium.

更新日期：2014-04-01 00:00:00

abstract：:After taking both conventional oral rizatriptan tablets and oral disintegrating rizatriptan tablets in the treatment of migraine with or without aura, patients were permitted to select their formulation preference. All adult patients who had requested continuation of rizatriptan during a 6-month period were included i...

journal_title：Headache

authors： Adelman JU,Mannix LK,Von Seggern RL

更新日期：2000-05-01 00:00:00

abstract：:Observations including the long-recognized tendency of migraine to run in families, the high concordance rates for migraine in twins reared together or apart, and the association of specific mutations with a rare migraine form are consistent with a genetic contribution to the disorder. This paper summarizes major find...

journal_title：Headache

authors： Gardner KL

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVES:This cross-sectional study examined the association between adverse childhood experiences (ACEs) and history of frequent headaches (including migraine) among children 3-17 years old using data from the 2016 and 2017 U.S. National Survey of Children's Health (NSCH). BACKGROUND:ACEs include abuse (physical, e...

journal_title：Headache

authors： Mansuri F,Nash MC,Bakour C,Kip K

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:Presentation of pooled analysis of safety data for fremanezumab in patients with chronic (CM) or episodic migraine (EM) from 4 placebo-controlled phase 2b and phase 3 studies. BACKGROUND:There is a need for an effective, safe, and well-tolerated preventive therapy that specifically targets the pathophysiolog...

journal_title：Headache

authors： Silberstein SD,McAllister P,Ning X,Faulhaber N,Lang N,Yeung P,Schiemann J,Aycardi E,Cohen JM,Janka L,Yang R

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:To characterize adult patients with episodic migraine who achieved 100% response to galcanezumab treatment. BACKGROUND:Galcanezumab is a humanized monoclonal antibody that selectively binds to the calcitonin gene-related peptide (CGRP) and has demonstrated efficacy in reducing migraine headache days (MHD) in...

journal_title：Headache

authors： Rosen N,Pearlman E,Ruff D,Day K,Jim Nagy A

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy of celecoxib for treatment of withdrawal headache vs prednisone in patients with medication overuse headache (MOH). METHODS:In this prospective, double-blind, parallel-group clinical trial, 97 consecutive subjects with MOH were randomized (simple randomization using computer-generated...

journal_title：Headache

authors： Taghdiri F,Togha M,Razeghi Jahromi S,Paknejad SM

更新日期：2015-01-01 00:00:00

abstract：:Botulinum toxin type A, a protein long used in the successful treatment of various dystonias, has a complex mechanism of action that results in muscle relaxation. At the neuromuscular junction, the presynaptic nerve ending is packed with synaptic vesicles filled with acetylcholine, and clustered at the tip of the fold...

journal_title：Headache

authors： Dolly O

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:This study compared clinical manifestations and audiovestibular function tests among subjects of basilar-type migraine (BtM), definite and probable migrainous vertigo (dMV and pMV), in order to investigate the relationship between them. BACKGROUND:Various diagnostic criteria such as BtM, dMV, and pMV have be...

journal_title：Headache

authors： Wang CT,Lai MS,Young YH

更新日期：2009-03-01 00:00:00

abstract：:Three decades of research has produced effective behavioral treatments for migraine and tension-type headache, yet the full fruition of this research has not been realized. Further development and dissemination of behavioral treatments is needed to impact the large numbers of those with headache who potentially could ...

journal_title：Headache

authors： Penzien DB,Rains JC,Lipchik GL,Nicholson RA,Lake AE 3rd,Hursey KG

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:In this study, we explored the relationship between migraine and sport in a physically active population of students, analyzing the risk of migraine among sporty students. BACKGROUND:The relationship between sport and migraine is controversial; moreover, several studies report on sport as a migraine trigger,...

journal_title：Headache

authors： Pilati L,Battaglia G,Di Stefano V,Di Marco S,Torrente A,Raieli V,Firenze A,Salemi G,Brighina F

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To describe acute headache diagnoses in women presenting emergently in the postpartum period and to determine which factors may be associated with secondary vs primary headache. BACKGROUND:Hormonal, vascular, and procedural factors elevate the risk for both secondary and primary headache disorders in the pos...

journal_title：Headache

authors： Vgontzas A,Robbins MS

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact on costs and outcomes of early migraine treatment with sumatriptan while pain is mild versus sumatriptan treatment of moderate to severe pain. BACKGROUND:Migraines result in substantial pain, impairment, and costs. Recent clinical studies have shown that early treatment with sumatripta...

journal_title：Headache

authors： Halpern MT,Lipton RB,Cady RK,Kwong WJ,Marlo KO,Batenhorst AS

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Oxygen and triptans are drugs of first choice to abort cluster headache attacks. However, clinical predictors of treatment response are unavailable. OBJECTIVE:We aimed to identify predictors of acute treatment response among patients with cluster headache. METHODS:We investigated 246 cluster headache patie...

journal_title：Headache

authors： Schürks M,Rosskopf D,de Jesus J,Jonjic M,Diener HC,Kurth T

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Persistent migraine aura without infarction (PMA) is a rare condition that is defined as an aura that lasts longer than 1 week in absence of infarction. Two types of PMA have been distinguished, notably persistent primary visual disturbance (PPVD) and typical aura (TA). OBJECTIVES:This case-based review art...

journal_title：Headache

authors： Thissen S,Vos IG,Schreuder TH,Schreurs WM,Postma LA,Koehler PJ

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:To investigate differences in topographical pressure pain sensitivity maps of the scalp between patients with migraine and healthy controls considering the chronicity (episodic/chronic) and side (strictly unilateral/bilateral) of the symptoms. BACKGROUND:It seems that the trigeminal area is sensitized in mig...

journal_title：Headache

authors： Barón J,Ruiz M,Palacios-Ceña M,Madeleine P,Guerrero ÁL,Arendt-Nielsen L,Fernández-de-Las-Peñas C

更新日期：2017-02-01 00:00:00

abstract：:Recent research on headache has focused on identifying the prevalence of psychiatric disorders in headache patients and discerning the impact of psychiatric comorbidity on treatment of headache. The presence of comorbid psychiatric disorders, especially anxiety and depression, in headache patients is now a well-docume...

journal_title：Headache

authors： Lipchik GL,Smitherman TA,Penzien DB,Holroyd KA

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:To determine the effect of a sympathetic block at C7 on cluster headache. BACKGROUND:Eleven patients presenting to a pain control unit with cluster headache were included in the study after giving informed consent. METHODS:In all patients, a mixture of 5 mL of 0.5% bupivacaine hydrochloride and 1 cc of meth...

journal_title：Headache

authors： Albertyn J,Barry R,Odendaal CL

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Dihydroergotamine (DHE) has been used for decades to treat migraine, but is currently contraindicated in patients with hemiplegic migraine and basilar-type migraine (BTM). OBJECTIVE:To assess the safety of DHE in patients with symptoms of BTM that do not meet criteria for BTM. METHODS:Retrospective analysi...

journal_title：Headache

authors： Whyte CA,Stillman MJ,Tepper SJ

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To describe the relationship between mood/anxiety disorders and migraine headaches emphasizing the frequency of episodes based in a cross-sectional analysis in the Brazilian Longitudinal Study of Adult Health. BACKGROUND:It has been suggested that frequency of migraine headaches can be directly associated wi...

journal_title：Headache

authors： Goulart AC,Santos IS,Brunoni AR,Nunes MA,Passos VM,Griep RH,Lotufo PA,Benseñor IM

更新日期：2014-09-01 00:00:00

abstract：:Magnetic resonance (MR) angiography was performed during and between two spontaneous and untreated attacks in a 24-year old male patient with episodic cluster headache. The ipsilateral ophthalmic artery was observed to be markedly dilated during both attacks. No changes were seen in the internal carotid artery or any ...

journal_title：Headache

authors： Waldenlind E,Ekbom K,Torhall J

更新日期：1993-06-01 00:00:00

abstract：OBJECTIVES:To compare the relative tolerability of 5-HT1B/1D agonists and to investigate the relationships (if any) among systemic exposure, lipophilicity, and clinical tolerability for 5-HT1B/1D agonists. METHODS:Post hoc correlations were sought among the following variables: absolute dose (= administered dose x ora...

journal_title：Headache

authors： Fox AW

更新日期：2000-07-01 00:00:00

abstract：:Imaging studies of spontaneous migraine aura have proved challenging because of the episodic and unpredictable nature of migraine attacks. Two patients with signs of acute ischemic stroke were evaluated for thrombolysis and turned out to suffer from familial hemiplegic migraine. It was possible to record the early pha...

journal_title：Headache

authors： Hansen JM,Schytz HW,Larsen VA,Iversen HK,Ashina M

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVES:To report the case of a patient enduring migraine attacks preceded by hallucinatory olfactory symptoms, with characteristics which typically define migraine with aura (MWA). BACKGROUND:MWA accounts for about 30-40% of the total cases of migraine and is almost always preceded by visual disorders; and in rare...

journal_title：Headache

authors： Tiriticco M,Vanotti A,Mantica D,Coppola A

更新日期：2020-11-01 00:00:00

abstract：PREMISE:Trigeminal neuralgia is a severe facial pain disorder that has been studied for decades. Classical trigeminal neuralgia (CTN) is either idiopathic or caused by neurovascular compression. The related painful trigeminal neuropathies are often secondary to other causes, such as multiple sclerosis or trauma. PROBL...

journal_title：Headache

authors： Weber K

更新日期：2017-11-01 00:00:00