Synaptic transmission: inhibition of neurotransmitter release by botulinum toxins.

abstract：:We describe a patient with atypical headache as the only presenting symptom of spontaneous triple cervical artery dissection. As the patient suffered from arterial hypertension, a causative relation between headache and arterial hypertension was initially taken into consideration. However, four-vessel arteriography di...

journal_title：Headache

authors： Buyle M,Engelborghs S,Kunnen J,De Deyn PP

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:This study aimed to evaluate the association between misdiagnosis of spontaneous intracranial hypotension (SIH) and subdural hematoma development. BACKGROUND:Although SIH is more prevalent than expected and causes potentially life-threatening complications including subdural hematoma (SDH), the association b...

journal_title：Headache

authors： Kim YJ,Cho HY,Seo DW,Sohn CH,Ahn S,Lee YS,Kim WY,Lim KS

更新日期：2017-11-01 00:00:00

abstract：:Pharmacological preparations of cannabinoid compounds have a variety of therapeutic uses in medicine, including different pain syndromes, but have not been previously reported as beneficial for cluster headache. We present a patient with cluster headache who was refractory to multiple acute and preventive medications ...

journal_title：Headache

authors： Robbins MS,Tarshish S,Solomon S,Grosberg BM

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Although naratriptan is not approved for prophylactic use in migraine, naratriptan has been shown to be significantly more effective than placebo for short-term prevention of menstrually related migraine (MRM). The tolerability of naratriptan administered intermittently for prophylaxis for MRM over the long ...

journal_title：Headache

authors： Brandes JL,Smith T,Diamond M,Ames MH

更新日期：2007-06-01 00:00:00

abstract：:Patients suffering from cervicogenic headache (CeH) are commonly treated with spinal manipulative therapy. We have analyzed the quality and the outcomes of published, randomized, controlled trials assessing the effectiveness of spinal manipulation in CeH. Among 121 relevant articles, only two met all the inclusion cri...

journal_title：Headache

authors： Fernández-de-Las-Peñas C,Alonso-Blanco C,Cuadrado ML,Pareja JA

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the prevalence of migraine/severe headaches in those with and without general obesity and abdominal obesity (Abd-O) and the effect of gender and age on this relationship. BACKGROUND:General, or total body obesity (TBO), as estimated by body mass index, is a risk factor for migraine chronification...

journal_title：Headache

authors： Peterlin BL,Rosso AL,Rapoport AM,Scher AI

更新日期：2010-01-01 00:00:00

abstract：:The Monks of Athos in Greece constitute a particular group with unusual sleep schedule and specific diet. In order to study the frequency of headache among them, a special questionnaire was designed. Four hundred forty-nine monks below the age of 50 were approached, 39 of whom suffered from frequent (more than one epi...

journal_title：Headache

authors： Mitsikostas DD,Thomas A,Gatzonis S,Ilias A,Papageorgiou C

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:To assess, in the setting of routine clinical practice, rizatriptan's effectiveness in treating acute migraine at its onset versus in a later phase of the attack. BACKGROUND:Although the efficacy and tolerability of rizatriptan have been well documented in clinical trials, no information is available about t...

journal_title：Headache

authors： Hu XH,Raskin NH,Cowan R,Markson LE,Berger ML,United States Migraine Study Protocol (USMAP) Group.

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Neck muscle nociception mediated by nitric oxide may play a role in the pathophysiology of tension-type headache. OBJECTIVE:The present study addresses the involvement of neuronal nitric oxide synthase (nNOS) in the facilitation of neck muscle nociception after local application of nerve growth factor (NGF)...

journal_title：Headache

authors： Isaak A,Ellrich J

更新日期：2011-05-01 00:00:00

abstract：:Two sisters with cluster headache were studied with respect to the pupillary responses to instillation into the conjunctival sac of a single drop of a 1% solution of phenylephrine and a 2% solution of tyramine. The changes in pupillary diameters were documented by photographic pupillometry prior to and at 15, 30, 60, ...

journal_title：Headache

authors： Havelius U,Milos P,Hindfelt B

更新日期：1996-07-01 00:00:00

abstract：:This review considers current debate surrounding refractory migraine and poses the question, why do some patients fail to improve with currently available therapies? ...

journal_title：Headache

authors： Dodick DW

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:The periaqueductal gray matter (PAG) is at the center of a powerful descending antinociceptive neuronal network. We studied iron homeostasis in the PAG as an indicator of function in patients with episodic migraine (EM) between attacks and patients with chronic daily headache (CDH) during headache. High-resol...

journal_title：Headache

authors： Welch KM,Nagesh V,Aurora SK,Gelman N

更新日期：2001-07-01 00:00:00

abstract：:Epidemiologic studies provide estimates of the scope and distribution of the public health problems posed by migraine. These studies have been facilitated by the development of the International Headache Society criteria for migraine, which have now been used in separate prevalence studies in several countries. In thi...

journal_title：Headache

authors： Lipton RB,Silberstein SD,Stewart WF

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Neuromodulators such as topiramate (TPM) and divalproex sodium (DVS) are effective in the preventive treatment of migraine. Nonetheless, patients often discontinue their use due to side effects. OBJECTIVES:The study aims to determine whether the combination of lower doses of TPM and DVS may be useful for pa...

journal_title：Headache

authors： Krymchantowski AV,Jevoux Cda C

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To explore the effects of olmesartan on frequency and severity of migraine attacks in patients with comorbid hypertension and prehypertension. BACKGROUND:A randomized, double-blind, placebo-controlled, crossover study with a total of 60 patients has demonstrated the efficacy and safety of the angiotensin II ...

journal_title：Headache

authors： Charles JA,Jotkowitz S,Byrd LH

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Research imaging of brain structure and function has helped to elucidate the pathophysiology of medication overuse headache (MOH). METHODS:This is a narrative review of imaging research studies that have investigated brain structural and functional alterations associated with MOH. Studies included in this r...

journal_title：Headache

authors： Schwedt TJ,Chong CD

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Migraine is a common primary headache disorder occurring predominantly in a young, relatively healthy population. RESULTS:There is a growing literature on associations between migraine, especially migraine with aura, and ischemic stroke as well as other vascular events. Migraine as a risk factor for vascula...

journal_title：Headache

authors： Murinova N,Krashin DL,Lucas S

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:To understand treatment preferences of people with migraine and the relative importance of improvements in efficacy and avoiding adverse events (AEs), such as cognition problems or weight gain. BACKGROUND:Current preventive migraine medicines are associated with poor adherence and tolerability. There is an u...

journal_title：Headache

authors： Mansfield C,Gebben DJ,Sutphin J,Tepper SJ,Schwedt TJ,Sapra S,Shah N

更新日期：2019-05-01 00:00:00

abstract：:The efficacy of the repetitive intravenous dihydroergotamine (DHE) inpatient protocol for refractory headache is well established. We conducted a retrospective and prospective study of long-term headache patients at our clinic to evaluate this regimen in an outpatient setting. Treatment consisted of oral metoclopramid...

journal_title：Headache

authors： Robbins L,Remmes A

更新日期：1992-10-01 00:00:00

abstract：:Over the past few years, sports-related concussion has received significant media attention making it one of the most, if not highest profile neurological disorder. Thirty-one states now have passed sports concussion laws, with 14 states pending legislation. Most concussions are managed by primary care physicians, ie,...

journal_title：Headache

authors： Conidi FX

更新日期：2012-05-01 00:00:00

abstract：:Long-lasting severe headaches are reported to occur in up to 83% of patients who have undergone resection of acoustic neuroma, especially through a suboccipital approach. These headaches, however, are not well defined. The objective of this study was to assess the frequency and character of new-onset headaches after r...

journal_title：Headache

authors： Mosek AC,Dodick DW,Ebersold MJ,Swanson JW

更新日期：1999-02-01 00:00:00

abstract：:The author reports the use of pregabalin in a patient with glossopharyngeal neuralgia. The patient achieved complete pain relief and tolerated the medication. This is the first published report of the use of this medicine for glossopharyngeal neuralgia. ...

journal_title：Headache

authors： Kitchener JM

更新日期：2006-09-01 00:00:00

abstract：:Greater occipital nerve (GON) infiltration is widely used for the treatment of primary and secondary headache disorders mainly on the basis of open-label evidence, although recent double-blinded placebo-controlled trials have demonstrated its efficacy in cluster headache. The procedure is generally well tolerated alth...

journal_title：Headache

authors： Lambru G,Lagrata S,Matharu MS

更新日期：2012-11-01 00:00:00

abstract：:Ischemic colitis has not been reported in association with naratriptan therapy. We describe the occurrence of ischemic colitis in a patient who was treated with abortive doses of naratriptan for migraine and was also taking long-term oral contraceptives. Concurrent use of naratriptan and oral contraceptives should pro...

journal_title：Headache

authors： Charles JA,Pullicino PM,Stoopack PM,Shroff Y

更新日期：2005-04-01 00:00:00

abstract：:Attacks of chronic paroxysmal hemicrania are prevented by the continuous administration of indomethacin. Sumatriptan, an agonist of 5-HT1-like receptors, has proven effective in the treatment of cluster headache attacks. There are clear clinical similarities between chronic paroxysmal hemicrania and cluster headache. ...

journal_title：Headache

authors： Antonaci F,Pareja JA,Caminero AB,Sjaastad O

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:To describe the clinical features of children with chronic daily headache (CDH) and examine the usefulness of the International Classification of Headache Disorders-II. BACKGROUND:Few data are available on chronic daily headache and analgesic overuse in children and adolescents and there are no specific crit...

journal_title：Headache

authors： Wiendels NJ,van der Geest MC,Neven AK,Ferrari MD,Laan LA

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of different migraine prophylaxis medications on subject responsiveness to almotriptan. BACKGROUND:There is evidence supporting an increase of responsiveness of symptomatic medications for migraine attacks by some prophylactic treatments although this has not been probed. METHODS:A to...

journal_title：Headache

authors： Bermejo PE,Dorado R,Gomez-Arguelles JM

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Migraine is a highly prevalent disorder that imposes an important burden of disability to patients and has social and economic impact in developed countries. A good screening tool for migraine diagnosis is useful to improve disease identification and therapeutic approaches, hopefully reducing the burden of m...

journal_title：Headache

authors： Gil-Gouveia R,Martins I

更新日期：2010-03-01 00:00:00

abstract：OBJECTIVES:To investigate the efficacy and long-term outcome of intravenous prochlorperazine for the treatment of refractory chronic daily headache. BACKGROUND:Unlike dihydroergotamine, the treatment results of intravenous neuroleptics as first-line agents for refractory chronic daily headache have rarely been reporte...

journal_title：Headache

authors： Lu SR,Fuh JL,Juang KD,Wang SJ

更新日期：2000-10-01 00:00:00

abstract：:A 29-year-old woman presented with acute hemicrania, trigeminal neuropathy and posterior fossa dysfunction. The admission differential diagnosis included vertebral artery dissection, posterior circulation aneurysm, vascular malformation and brainstem infarction. However, radiographic and CSF studies indicated demyelin...

journal_title：Headache

authors： Nager BJ,Lanska DJ,Daroff RB

更新日期：1989-07-01 00:00:00