Abstract:
:Pharmacological preparations of cannabinoid compounds have a variety of therapeutic uses in medicine, including different pain syndromes, but have not been previously reported as beneficial for cluster headache. We present a patient with cluster headache who was refractory to multiple acute and preventive medications but successfully aborted his attacks with recreational marijuana use; subsequent use of dronabinol provided equally effective pain relief. The beneficial effect may be related to the high concentration of cannabinoid receptors in the hypothalamus, which has been implicated as a site of dysfunction in neuroimaging studies of patients with cluster headache.
journal_name
Headachejournal_title
Headacheauthors
Robbins MS,Tarshish S,Solomon S,Grosberg BMdoi
10.1111/j.1526-4610.2009.01344.xsubject
Has Abstractpub_date
2009-06-01 00:00:00pages
914-6issue
6eissn
0017-8748issn
1526-4610pii
HED1344journal_volume
49pub_type
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