Concepts and mechanisms of migraine chronification.

abstract：OBJECTIVE:To evaluate the association between a serotonin (5-HT) transporter gene polymorphism and migraines in Koreans. BACKGROUND:The 5-HT metabolism is believed to play an important part in the pathophysiology of migraines, and a polymorphism of the serotonin transporter (5-HTT) promoter region might influence 5-HT...

journal_title：Headache

authors： Kim WK,Kim HS,Kim WJ,Lee KY,Park H,Kim CH,Kim SJ,Choi YC

更新日期：2005-09-01 00:00:00

abstract：:Migraine and stroke are the most common neurovascular disorders affecting adults. Migraine, particularly with aura, is associated with increased stroke risk both during and between attacks; as such, migraine may be viewed as a potentially modifiable risk factor for stroke. The exact mechanism by which migraine can pre...

journal_title：Headache

authors： Alhazzani A,Goddeau RP

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:To assess the measurement properties of the Migraine-Specific Quality of Life Questionnaire version 2.1 (MSQv2.1) electronic patient-reported outcome (ePRO) Role Function-Restrictive (RFR) domain to evaluate the functional impact of migraine in patients with episodic (EM) or chronic migraine (CM) enrolled in...

journal_title：Headache

authors： Speck RM,Shalhoub H,Wyrwich KW,Yu R,Ayer DW,Ford J,Bush EN,Lipton RB

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Using standard quality of life and disability measures may not accurately capture these constructs in specific health populations such as headache patients. Modifying the wording of standard measures such as the Short-Form 36 (SF-36) should be considered in order to make them more applicable to specific pati...

journal_title：Headache

authors： Magnusson JE,Riess CM,Becker WJ

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and tolerability of sumatriptan nasal spray (NS) (5, 20 mg) versus placebo in the acute treatment of migraine in adolescent subjects. BACKGROUND:Currently, no triptan is approved in the United States for the treatment of migraine in adolescent subjects (12 to 17 years). In a previous ...

journal_title：Headache

authors： Winner P,Rothner AD,Wooten JD,Webster C,Ames M

更新日期：2006-02-01 00:00:00

abstract：:Several studies have examined patients' attitudes to a consultation for migraine and other headaches. However, a patient's assessment of the problem for which they seek treatment may differ from that of the referring primary physician which may, in turn, differ from the specialist's. This study set out to examine this...

journal_title：Headache

authors： Blau JN,MacGregor EA

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVES:The aim of our study was to investigate the prevalence of sleep disorders in chronic headache patients and to evaluate the role of psychiatric comorbidity in the association between chronic headache and sleep complaints. BACKGROUND:The prevalence of sleep disorders in chronic headache has been seldom invest...

journal_title：Headache

authors： Sancisi E,Cevoli S,Vignatelli L,Nicodemo M,Pierangeli G,Zanigni S,Grimaldi D,Cortelli P,Montagna P

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To identify and investigate any dysfunction of neuromuscular transmission in episodic cluster headache. BACKGROUND:Abnormal neuromuscular transmission has been shown in migraine with aura and in migraine without aura by using single fiber electromyography. Especially for migraine with aura, a genetic cause h...

journal_title：Headache

authors： Ertas M,Baslo MB

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:In the current literature, there is neither a reported systematic review comparing the efficacy of triptans at 30 minutes and 1 hour after the migraine treatment, nor data related to efficacy of new marketed triptans. OBJECTIVE:The main objective of this analysis was to compare the efficacy and tolerability...

journal_title：Headache

authors： Pascual J,Mateos V,Roig C,Sanchez-Del-Rio M,Jiménez D

更新日期：2007-09-01 00:00:00

abstract：:Forecasting how medicine will be practiced 50 years from now presents a challenge. While advances in technology will have a major impact, new cultural outlooks on physician professionalism and autonomy will have an even greater significance in daily practice. The current healthcare system is in crisis. As members of a...

journal_title：Headache

authors： Nash DB,Quigley GD

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVES:To evaluate the safety and efficacy of ketamine-magnesium combination to reduce attacks in a series of patients with refractory chronic cluster headache (rCCH). BACKGROUND:Refractory chronic cluster headache (CCH) is a rare but highly debilitating condition that needs new treatment options. A previous publi...

journal_title：Headache

authors： Moisset X,Giraud P,Meunier E,Condé S,Périé M,Picard P,Pereira B,Ciampi de Andrade D,Clavelou P,Dallel R

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:This study evaluated the effectiveness of a single fixed-dose tablet of sumatriptan 85 mg/naproxen sodium 500 mg (sumatriptan-naproxen) using a very early treatment paradigm in migraine patients whose attacks were historically accompanied by cutaneous allodynia. BACKGROUND:Evidence suggests that allodynic mi...

journal_title：Headache

authors： Landy S,Hoagland R,Hoagland NA

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:This cross-sectional study on a randomly drawn population sample of children and adolescents (n = 3399; aged 9 to 15) aimed at the assessment of patterns of associations between psychosocial variables and primary headache disorders like migraine (MIG) or tension-type headache. A headache-free group served as ...

journal_title：Headache

authors： Kröner-Herwig B,Gassmann J

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:It has been suggested that homocysteine (Hcy) and the 5'-10'-methylenetetrahydrofolate reductase (MTHFR) C677T variant are implicated in the pathogenesis of migraine. Homocysteine has the potential to damage endothelium and accelerate atherosclerosis. Genetic factors such as the MTHFR C677T polymorphism, and...

journal_title：Headache

authors： Oterino A,Toriello M,Valle N,Castillo J,Alonso-Arranz A,Bravo Y,Ruiz-Alegria C,Quintela E,Pascual J

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Recurrent headache sufferers are often fearful of pain, which disrupts thought processes, interferes with daily activities, and may maintain headache-related disability through avoidance and associated negative reinforcement. OBJECTIVE:The aim of this cross-sectional study was to (1) examine differences in ...

journal_title：Headache

authors： Black AK,Fulwiler JC,Smitherman TA

更新日期：2015-05-01 00:00:00

abstract：:A 25-year-old man, subject to bouts of left supraorbital cluster headache on an annual basis over the previous 8 years, volunteered for MRI angiography during an active period. Studies were conducted before and during a typical cluster headache attack induced by alcohol. MRI angiography failed to show dilatation of th...

journal_title：Headache

authors： Somerville B

更新日期：1994-09-01 00:00:00

abstract：:The discussion about neuropsychological sequalae from migraine occurring in adults is controversial. The purpose of our study was to examine whether children with migraine may be at risk for impaired intellectual development compared with their siblings free of migraine. ...

journal_title：Headache

authors： Haverkamp F,Hönscheid A,Müller-Sinik K

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:We aimed to report 6 new cases of bifocal nummular headache (NH), showing their clinical characteristics and comparing them with those formerly described. BACKGROUND:NH is a focal head pain felt in a small, well-circumscribed, coin-shaped area. Among all the reported cases (over 200), 6 patients localized th...

journal_title：Headache

authors： Guerrero AL,Cuadrado ML,García-García ME,Cortijo E,Herrero-Velázquez S,Rodríguez O,Mulero P,Porta-Etessam J

更新日期：2011-07-01 00:00:00

abstract：:Aspartame, a popular dietetic sweetener, may provoke headache in some susceptible individuals. Herein, we describe three cases of young women with migraine who reported their headaches could be provoked by chewing sugarless gum containing aspartame. ...

journal_title：Headache

authors： Blumenthal HJ,Vance DA

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:The present study endeavored to identify predictors of headache during pregnancy, shortly after delivery, and at 8-week follow-up. BACKGROUND:Many women suffer from headaches during pregnancy and the post-partum period. However, little is known about factors that predict headache surrounding childbirth. MET...

journal_title：Headache

authors： Turner DP,Smitherman TA,Eisenach JC,Penzien DB,Houle TT

更新日期：2012-03-01 00:00:00

abstract：:A 48-year-old slender woman presented with a rare case of spontaneous intracranial hypotension syndrome manifesting as patulous Eustachian tube. The patient complained of sudden onset of ear fullness and nasal voice as well as typical orthostatic headache. Patulous Eustachian tube was identified by observation of sync...

journal_title：Headache

authors： Horikoshi T,Imamura S,Matsuzaki Z,Umeda T,Uchida M,Mitsuka K,Kinouchi H

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:To investigate differences in topographical pressure pain sensitivity maps of the scalp between patients with migraine and healthy controls considering the chronicity (episodic/chronic) and side (strictly unilateral/bilateral) of the symptoms. BACKGROUND:It seems that the trigeminal area is sensitized in mig...

journal_title：Headache

authors： Barón J,Ruiz M,Palacios-Ceña M,Madeleine P,Guerrero ÁL,Arendt-Nielsen L,Fernández-de-Las-Peñas C

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:To report a case of petrous apicitis that manifested as chronic migraine without aura and to discuss the pathophysiological mechanisms behind this presentation. BACKGROUND:Petrous apicitis is a rare complication of acute otitis media with varied clinical presentations that stem from the close proximity of th...

journal_title：Headache

authors： Mancini AJ,Glassman RD,Chang YM,Burstein R,Ashina S

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:The role of diet in the management of the headache patient is a controversial topic in the headache field. OBJECTIVES:To review the evidence supporting the hypothesis that specific foods or ingredients within foods and beverages trigger attacks of headache and/or migraine and to discuss the use of eliminati...

journal_title：Headache

authors： Martin VT,Vij B

更新日期：2016-10-01 00:00:00

abstract：:This work assesses the differences in the thermographic findings in the craniofacial and neck areas between normal individuals and patients with craniofacial pain or headache, and investigates the influence of muscle contraction on such findings. Thermographic records were taken in 10 healthy subjects and 47 patients ...

journal_title：Headache

authors： Mongini F,Caselli C,Macrì V,Tetti C

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Several studies suggest an association between migraine and juvenile stroke. Because of some shortcomings, we designed another case-control study of a homogenous group of patients with juvenile cerebral ischemia. This study is part of a larger German epidemiological research project on the association of mig...

journal_title：Headache

authors： Schwaag S,Nabavi DG,Frese A,Husstedt IW,Evers S

更新日期：2003-02-01 00:00:00

abstract：:Flunarizine plasma concentrations and side effects were evaluated in migraine patients during a 3 month course of prophylactic treatment. Plasma concentrations did not correlate with daily dose (in mg/kg). Mean flunarizine levels were higher in patients showing sleepiness or sedation. Weight gain was independent of pl...

journal_title：Headache

authors： Albani F,Baldrati A,Cortelli P,Riva R,Baruzzi A

更新日期：1990-05-01 00:00:00

abstract：:It has been suggested that magnesium (Mg) may play a role in the pathogenesis of headaches. Serum and intracellular measurements of Mg in headache patients have produced inconsistent results. The recent development of an ion-selective electrode for Mg2+ allowed precise measurement of serum ionized magnesium (IMg2+) in...

journal_title：Headache

authors： Mauskop A,Altura BT,Cracco RQ,Altura BM

更新日期：1993-03-01 00:00:00

abstract：:Significant progress in molecular genetics has advanced our understanding of the genetic basis of migraine. The fundamentals of molecular genetics, and the recent advances in the field, are important for clinicians to understand, as they provide a foundation for critical appraisal of the literature, unprecedented insi...

journal_title：Headache

authors： Silberstein SD,Dodick DW

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Migraine is a common and often debilitating neurological disease. It can be divided into episodic and chronic subforms based on the number of monthly headache days. Because only a subset of individuals with episodic migraine (EM) progress to chronic migraine (CM) over any given time period, understanding the...

journal_title：Headache

authors： Buse DC,Greisman JD,Baigi K,Lipton RB

更新日期：2019-03-01 00:00:00