Outpatient repetitive intravenous dihydroergotamine.

Abstract:

:The efficacy of the repetitive intravenous dihydroergotamine (DHE) inpatient protocol for refractory headache is well established. We conducted a retrospective and prospective study of long-term headache patients at our clinic to evaluate this regimen in an outpatient setting. Treatment consisted of oral metoclopramide and four doses of DHE, with the total dose equaling 4 mg., administered over two days. Patients were followed for up to 10 weeks while they continued to receive prophylactic medication. Responsiveness was rated in terms of decreased frequency or severity of headache: excellent (75% to 100%), moderate (50-75%), mild (25-50%), and none (0-25%). In the retrospective study, 69% (43/62) of patients with chronic daily muscle-contraction-type headache and severe migraine had an excellent response at two days. An excellent or moderate response was sustained over three weeks in 65% (32/49) of the study group (13 patients were dropped from the study for failing to comply with record keeping requirements). At the 6- and 10-week follow-up evaluations, the majority of patients (76% and 70%, respectively) reported mild or no relief. Among patients with refractory daily headache or frequent severe migraine studied prospectively, 80% (28/35) reported an excellent response at two days. After six weeks, 66% (23/35) showed excellent or moderate relief. For both groups combined, 73% (71/97) of patients showed an excellent response to DHE at two days, with 43% (33/77) sustaining excellent or moderate relief at six weeks. Side effects, including nausea, leg cramps, facial flushing, increased blood pressure, diarrhea, burning at the injection site, and tightness in the throat and/or chest, were generally mild and transient.(ABSTRACT TRUNCATED AT 250 WORDS)

journal_name

Headache

journal_title

Headache

authors

Robbins L,Remmes A

doi

10.1111/j.1526-4610.1992.hed3209455.x

keywords:

subject

Has Abstract

pub_date

1992-10-01 00:00:00

pages

455-8

issue

9

eissn

0017-8748

issn

1526-4610

journal_volume

32

pub_type

杂志文章

相关文献

HEADACHE文献大全
  • Ankle-brachial index, a screening for peripheral obstructive arterial disease, and migraine - a controlled study.

    abstract:BACKGROUND:Epidemiological studies support the association between migraine, especially migraine with aura, and vascular disorders. The ankle-brachial index (ABI) is largely used as a surrogate of peripheral obstructive arterial disorders (POAD). Accordingly, in this study we contrasted the ABI in individuals with migr...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2009.01536.x

    authors: Jurno ME,Chevtchouk L,Nunes AA,de Rezende DF,Jevoux Cda C,de Souza JA,Moreira Filho PF

    更新日期:2010-04-01 00:00:00

  • Zonisamide for migraine prophylaxis in topiramate-intolerant patients: an observational study.

    abstract:BACKGROUND:Zonisamide, a sulfonamide analog, is an antiepileptic drug with mechanisms of action similar to topiramate. Because of its pharmacodynamic and pharmacokinetics profiles, zonisamide is also potentially suitable for migraine prevention. METHODS:Tolerability and effectiveness of zonisamide for migraine prophyl...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2010.01842.x

    authors: Villani V,Ciuffoli A,Prosperini L,Sette G

    更新日期:2011-02-01 00:00:00

  • Reduction in the intensity of abortive migraine drug use during coumarin therapy.

    abstract:OBJECTIVE:To investigate the impact of coumarin therapy on migraine attack frequency. BACKGROUND:Sporadic case reports and clinical studies have described beneficial effects of coumarin therapy on migraine severity. DESIGN AND METHODS:A retrospective follow-up study based on a prescription database covering a populat...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.2001.01141.x

    authors: Rahimtoola H,Egberts AC,Buurma H,Tijssen CC,Leufkens HG

    更新日期:2001-09-01 00:00:00

  • Hemicrania continua: a case responsive to piroxicam-beta-cyclodextrin.

    abstract::The case of a 53-year-old woman is described, who since the age of 38 years had been suffering from a unilateral headache that was at first remitting, but then evolved into an unremitting course. The headache was burning in quality, located in the left forehead and face, and was accompanied by mild ipsilateral autonom...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.1992.hed3201039.x

    authors: Trucco M,Antonaci F,Sandrini G

    更新日期:1992-01-01 00:00:00

  • Higher prevalence of psychopathological symptoms in adolescents with headache. A population-based cross-sectional study.

    abstract:BACKGROUND:Headache is commonly voiced by adolescents and is known to be associated with reduced quality of life. Otherwise, there are only limited data regarding associations between different types of headache and psychopathological symptoms in adolescents. OBJECTIVES:Aim of the present study in adolescents was to a...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2009.01605.x

    authors: Milde-Busch A,Boneberger A,Heinrich S,Thomas S,Kühnlein A,Radon K,Straube A,von Kries R

    更新日期:2010-05-01 00:00:00

  • Alteration of central excitation circuits in chronic headache and analgesic misuse.

    abstract::Central excitatory circuits could be involved in the pathophysiology of pain; particularly, the genesis of chronic pain. The "second pain" is the sensation that follows the initial pain after an appropriate nociceptive stimulus. The second pain is amplified by repeating the stimulus after brief intervals (temporal sum...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.1997.3708486.x

    authors: Fusco BM,Colantoni O,Giacovazzo M

    更新日期:1997-09-01 00:00:00

  • The first 5 minutes after greater occipital nerve block.

    abstract::We performed greater occipital nerve blocks on 24 migraineurs with unilateral migraine and trigeminal nerve distribution allodynia. Using a visual analog scale for migraine pain, brush allodynia in the trigeminal nerve distribution and photophobia were reduced 64%, 75%, and 67%, respectively, after 5 minutes. Allodyni...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2008.01146.x

    authors: Young W,Cook B,Malik S,Shaw J,Oshinsky M

    更新日期:2008-07-01 00:00:00

  • Pharmacokinetics of tiaprofenic acid after oral administration in fasting patients during and between migraine attacks.

    abstract::This study examined the pharmacokinetics of 300 mg of tiaprofenic acid, a NSAID belonging to the 2-arylpropionic class, as a single oral dose, in 10 migraine patients during and out of migraine attacks. Plasma concentration of tiaprofenic acid was determined by HPLC analysis. Drug absorption appeared to be the same du...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.1990.hed3010672.x

    authors: Pini LA,Bertolotti M,Bergonzini G,Casalgrandi L,Giroldi L,Sternieri E

    更新日期:1990-10-01 00:00:00

  • Loss of productivity and quality of life in migraine sufferers among French workers: results from the GAZEL cohort.

    abstract::To assess the burden of migraine, we compared the productivity and the perceived health of 991 migraine sufferers (IHS criteria), 1,004 other-headache sufferers, and 1,757 nonheadache sufferers randomly chosen among volunteers from employees of the French national gas and electricity company. The extent of absenteeism...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.1997.3702071.x

    authors: Michel P,Dartigues JF,Lindoulsi A,Henry P

    更新日期:1997-02-01 00:00:00

  • Sensitivity to various stimuli in primary headaches: a questionnaire study.

    abstract::Questions about discomfort or pain produced by various stimuli (e.g., light, sound, exercise, neck movements) are currently used to differentiate between various primary headache disorders. In order to evaluate the usefulness of differences in sensitivity to physical stimuli in headache diagnosis, the answers to a que...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.1999.3908552.x

    authors: Vingen JV,Sand T,Stovner LJ

    更新日期:1999-09-01 00:00:00

  • A Brief Look at Urgent Care Visits for Migraine: The Care Received and Ideas to Guide Migraine Care in this Proliferating Medical Setting.

    abstract:OBJECTIVE:There has been a rise in urgent care centers throughout the country over the past 10 years, leading to an increase in patients accessing medical care in these locations. These centers advertise an alternative to the Emergency Department (ED) for the evaluation and treatment of urgent medical conditions. The g...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.13717

    authors: Minen MT,Zhou K,Miller L

    更新日期:2020-03-01 00:00:00

  • Analysis of Initial Nonresponders to Galcanezumab in Patients With Episodic or Chronic Migraine: Results From the EVOLVE-1, EVOLVE-2, and REGAIN Randomized, Double-Blind, Placebo-Controlled Studies.

    abstract:OBJECTIVE:To examine the likelihood of response with continued galcanezumab treatment in patients with episodic or chronic migraine without initial clinical improvement. BACKGROUND:A percentage of patients with migraine may require additional time on pharmacotherapy but discontinue treatment prematurely. Additionally,...

    journal_title:Headache

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/head.13443

    authors: Nichols R,Doty E,Sacco S,Ruff D,Pearlman E,Aurora SK

    更新日期:2019-02-01 00:00:00

  • Dialysis Headache: A Narrative Review.

    abstract:BACKGROUND:Patients with chronic kidney disease who need dialysis often have poor quality of life. Dialysis headache is a frequent complication of hemodialysis and is often a challenge for nephrologists, neurologists, and headache specialists. METHOD:This was a narrative review. RESULTS:The prevalence of dialysis hea...

    journal_title:Headache

    pub_type: 杂志文章,评审

    doi:10.1111/head.12875

    authors: Sousa Melo E,Carrilho Aguiar F,Sampaio Rocha-Filho PA

    更新日期:2017-01-01 00:00:00

  • Costs and outcomes of early versus delayed migraine treatment with sumatriptan.

    abstract:OBJECTIVE:To evaluate the impact on costs and outcomes of early migraine treatment with sumatriptan while pain is mild versus sumatriptan treatment of moderate to severe pain. BACKGROUND:Migraines result in substantial pain, impairment, and costs. Recent clinical studies have shown that early treatment with sumatripta...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.2002.02228.x

    authors: Halpern MT,Lipton RB,Cady RK,Kwong WJ,Marlo KO,Batenhorst AS

    更新日期:2002-11-01 00:00:00

  • Insomnia and perceptual disturbances during flunarizine treatment.

    abstract::We report two cases of sleep disturbances and perceptual disorder appearing in close temporal relationship with initiation of flunarizine therapy for migraine prophylaxis: these side effects disappeared after therapy interruption; resumption of the drug in one case was associated with symptom recurrence. ...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.1990.hed3002062.x

    authors: Dalla Volta G,Magoni M,Cappa S,Di Monda V

    更新日期:1990-01-01 00:00:00

  • Young Adults With Headaches: The Transition From Adolescents to Adults.

    abstract::Migraine is a common condition that for many begins in childhood and may progress over the course of one's life. The transition from adolescence to adulthood is a critical time for those who suffer from migraine and can be marked by a variety of important considerations for the patient and practitioner. Medication cho...

    journal_title:Headache

    pub_type: 杂志文章,评审

    doi:10.1111/head.12706

    authors: O'Brien HL,Cohen JM

    更新日期:2015-11-01 00:00:00

  • Examination of unmet treatment needs among persons with episodic migraine: results of the American Migraine Prevalence and Prevention (AMPP) Study.

    abstract:BACKGROUND:Despite the expanding therapeutic armamentarium, many people with episodic migraine (EM) have unmet acute treatment needs. OBJECTIVE:To determine the relative frequency of prespecified types of "unmet treatment needs" in persons with EM in a US population-based sample. METHODS:Eligible participants complet...

    journal_title:Headache

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/head.12154

    authors: Lipton RB,Buse DC,Serrano D,Holland S,Reed ML

    更新日期:2013-09-01 00:00:00

  • Ubrogepant, an Acute Treatment for Migraine, Improved Patient-Reported Functional Disability and Satisfaction in 2 Single-Attack Phase 3 Randomized Trials, ACHIEVE I and II.

    abstract:OBJECTIVE:To evaluate the efficacy of ubrogepant on patient-reported functional disability, satisfaction with study medication, and global impression of change. BACKGROUND:Ubrogepant is a small-molecule, oral calcitonin gene-related peptide receptor antagonist indicated for the acute treatment of migraine. In 2 phase ...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.13766

    authors: Dodick DW,Lipton RB,Ailani J,Halker Singh RB,Shewale AR,Zhao S,Trugman JM,Yu SY,Viswanathan HN

    更新日期:2020-04-01 00:00:00

  • Acute demyelination mimicking vascular hemicrania.

    abstract::A 29-year-old woman presented with acute hemicrania, trigeminal neuropathy and posterior fossa dysfunction. The admission differential diagnosis included vertebral artery dissection, posterior circulation aneurysm, vascular malformation and brainstem infarction. However, radiographic and CSF studies indicated demyelin...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.1989.hed2907423.x

    authors: Nager BJ,Lanska DJ,Daroff RB

    更新日期:1989-07-01 00:00:00

  • Patulous Eustachian tube in spontaneous intracranial hypotension syndrome.

    abstract::A 48-year-old slender woman presented with a rare case of spontaneous intracranial hypotension syndrome manifesting as patulous Eustachian tube. The patient complained of sudden onset of ear fullness and nasal voice as well as typical orthostatic headache. Patulous Eustachian tube was identified by observation of sync...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2006.00661.x

    authors: Horikoshi T,Imamura S,Matsuzaki Z,Umeda T,Uchida M,Mitsuka K,Kinouchi H

    更新日期:2007-01-01 00:00:00

  • Neuromodulation and Devices in Trigeminal Neuralgia.

    abstract:PREMISE:Trigeminal neuralgia is a severe facial pain disorder that has been studied for decades. Classical trigeminal neuralgia (CTN) is either idiopathic or caused by neurovascular compression. The related painful trigeminal neuropathies are often secondary to other causes, such as multiple sclerosis or trauma. PROBL...

    journal_title:Headache

    pub_type: 杂志文章,评审

    doi:10.1111/head.13166

    authors: Weber K

    更新日期:2017-11-01 00:00:00

  • Coping style and social support in men and women suffering from cluster headache or migraine.

    abstract:OBJECTIVE:To investigate similarities and differences between patients with cluster headache and patients with migraine. BACKGROUND:Patients with migraine and patients with cluster headache are considered, by many clinical neurologists, to be different psychologically and socially. METHODS:Twenty-five age-matched pai...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.2002.02049.x

    authors: Blomkvist V,Hannerz J,Katz L,Theorell T

    更新日期:2002-03-01 00:00:00

  • Intracranial hypertension and levofloxacin: a case report.

    abstract::This is a case report of a 15-year-old boy who developed benign intracranial hypertension after 3 weeks of levofloxacin intake. The headache, diplopia, and papilledema resolved within a week after levofloxacin was withdrawn. Physicians must be aware that quinolone antibiotics can potentially cause intracranial hyperte...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2008.01212.x

    authors: Lardizabal DV

    更新日期:2009-02-01 00:00:00

  • Factors Associated with Primary Headache According to Diagnosis, Sex, and Social Group.

    abstract:BACKGROUND:We previously showed that migraine and tension-type headache (TTH) have a high prevalence that differs markedly between social groups. Here, we aim to identify factors associated with migraine and TTH (possible risk factors) in three social groups to better understand the difference in prevalence between sex...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.12757

    authors: Lebedeva ER,Kobzeva NR,Gilev DV,Olesen J

    更新日期:2016-02-01 00:00:00

  • Headache diary in the diagnosis of childhood migraine.

    abstract::The usefulness of a headache diary in the diagnosis of migraine and in the clarification of migraine symptoms was studied in 145 children. These children belong to a 1-year age cohort of 5356 children that has been followed since birth. The children were enrolled in the present study according to their headache status...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.1997.3704240.x

    authors: Metsähonkala L,Sillanpää M,Tuominen J

    更新日期:1997-04-01 00:00:00

  • Where SUNCT contacts TN: a case report.

    abstract:BACKGROUND:Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) and trigeminal neuralgia (TN) are unilateral painful conditions that can share the same triggering factors, autonomic features and the main location, as well as the cyclically recurrent crises. Both these syndromes...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.12007

    authors: Rinaldi F,Rao R,Venturelli E,Liberini P,Gipponi S,Pari E,Sapia E,Padovani A

    更新日期:2013-10-01 00:00:00

  • Drug induced intracranial hypertension associated with sulphasalazine treatment.

    abstract::A 25-year-old female patient developed headache and papilledema under sulphasalazine treatment for ulcerative colitis. The patient met the International Headache Society's criteria for idiopathic intracranial hypertension. Sulphasalazine was discontinued and the patient was given azathioprine for ulcerative colitis an...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2007.00992.x

    authors: Sevgi E,Yalcin G,Kansu T,Varli K

    更新日期:2008-02-01 00:00:00

  • The efficacy and safety of venlafaxine in the prophylaxis of migraine.

    abstract:OBJECTIVE:To evaluate the efficacy and safety of venlafaxine in the prophylaxis of migraine. BACKGROUND:The efficacy of venlafaxine, which is selectively effective on the serotonergic and noradrenergic mechanisms, on various headaches and chronic pain syndromes has been demonstrated. To our knowledge, this is the firs...

    journal_title:Headache

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1526-4610.2005.05029.x

    authors: Ozyalcin SN,Talu GK,Kiziltan E,Yucel B,Ertas M,Disci R

    更新日期:2005-02-01 00:00:00

  • An analysis of migraine triggers in a clinic-based population.

    abstract:BACKGROUND:Many migraineurs report attack "triggers," but relatively few published data exist regarding the relative prevalences of individual triggers, variations related to gender, duration of migraine or migraine subtype, or the existence of any regional variations in the prevalences and distributions of triggers. ...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2010.01753.x

    authors: Andress-Rothrock D,King W,Rothrock J

    更新日期:2010-09-01 00:00:00

  • The relationship between homocysteine and genes of folate-related enzymes in migraine patients.

    abstract:BACKGROUND:It has been suggested that homocysteine (Hcy) and the 5'-10'-methylenetetrahydrofolate reductase (MTHFR) C677T variant are implicated in the pathogenesis of migraine. Homocysteine has the potential to damage endothelium and accelerate atherosclerosis. Genetic factors such as the MTHFR C677T polymorphism, and...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2009.01484.x

    authors: Oterino A,Toriello M,Valle N,Castillo J,Alonso-Arranz A,Bravo Y,Ruiz-Alegria C,Quintela E,Pascual J

    更新日期:2010-01-01 00:00:00