Abstract:
:We present a patient with treatment refractory short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) who was found to have low levels of serum testosterone supporting the hypothalamic connection to this trigeminal autonomic cephalalgia. Clomiphene citrate therapy induced a significant elevation of testosterone levels (by its effect on hypothalamic estrogen receptors) and led to a dramatic reduction in SUNCT attacks. Hormonal manipulation may be a treatment strategy for hypothalamic-influenced trigeminal autonomic cephalalgias.
journal_name
Headachejournal_title
Headacheauthors
Rozen TD,Saper JR,Sheftell FD,Dodick DWdoi
10.1111/j.1526-4610.2005.05143_2.xkeywords:
subject
Has Abstractpub_date
2005-06-01 00:00:00pages
754-6issue
6eissn
0017-8748issn
1526-4610pii
HED05143_2journal_volume
45pub_type
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