The risk of newly diagnosed asthma in migraineurs with or without previous triptan prescriptions.


BACKGROUND:Previous observational studies reported an increased prevalence of asthma in migraine patients. Whether triptans affect the asthma risk has not yet been explored in an epidemiological study. OBJECTIVE:To estimate the risk of newly diagnosed asthma in patients with a general practitioner-diagnosed migraine in the UK between 1994 and 2001. METHODS:A population-based follow-up study and a nested case-control analysis were conducted using the General Practice Research Database. RESULTS:The study encompassed 51,688 migraineurs and the same number of matched controls. In the follow-up analysis, the relative risk of developing asthma in migraineurs compared with non-migraineurs was 1.3 (95% confidence interval [CI] 1.1-1.4). In the nested case-control analysis, the adjusted odds ratio for asthma in migraineurs overall was 1.17 (95% CI 1.01-1.35), and for those with a recent triptan prescription 1.12 (95% CI 0.65-1.94). CONCLUSION:The risk of developing asthma was not materially altered for patients with a general practitioner-recorded migraine diagnosis, regardless of triptan use.






Becker C,Brobert GP,Almqvist PM,Johansson S,Jick SS,Meier CR




Has Abstract


2008-04-01 00:00:00
















  • Promote Biomarker Discovery by Identifying Homogenous Primary Headache Subgroups.

    abstract::Within- and between-study heterogeneity impede identification of valid primary headache biomarkers. Homogenous subgroup identification and investigation of differential biochemical profiles and networks within and across headache categories, based on statistical techniques, might promote biomarker discovery. When stud...


    pub_type: 杂志文章,评审


    authors: Frederiksen SD

    更新日期:2019-05-01 00:00:00

  • Acupuncture for treating acute attacks of migraine: a randomized controlled trial.

    abstract:OBJECTIVE:To discuss the results of a multicenter randomized controlled trial of the efficacy of verum acupuncture in treating acute migraine attacks. BACKGROUND:Acupuncture has been used in China for centuries to treat migraine headache. Convincing evidence of its efficacy in alleviating pain, however, has been inade...


    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Li Y,Liang F,Yang X,Tian X,Yan J,Sun G,Chang X,Tang Y,Ma T,Zhou L,Lan L,Yao W,Zou R

    更新日期:2009-06-01 00:00:00

  • Activation of pain fibers to the internal carotid artery intracranially may cause the pain and local signs of reduced sympathetic and enhanced parasympathetic activity in cluster headache.

    abstract::Several clinical and circulatory physiological observations indicate that the internal carotid artery (ICA) with proximal pial and orbital-periorbital branches, as well as external carotid vessels adjacent to the orbital region, are involved in the autonomic symptoms of an attack of cluster headache. Evidence is prese...


    pub_type: 杂志文章,评审


    authors: Hardebo JE

    更新日期:1991-05-01 00:00:00

  • Thermographic findings in cranio-facial pain.

    abstract::This work assesses the differences in the thermographic findings in the craniofacial and neck areas between normal individuals and patients with craniofacial pain or headache, and investigates the influence of muscle contraction on such findings. Thermographic records were taken in 10 healthy subjects and 47 patients ...


    pub_type: 杂志文章


    authors: Mongini F,Caselli C,Macrì V,Tetti C

    更新日期:1990-07-01 00:00:00

  • Triptan education and improving knowledge for optimal migraine treatment: an observational study.

    abstract:BACKGROUND:It is generally felt that patient education and patient knowledge regarding triptan use for acute migraine management are important for successful and safe treatment. It is unclear how knowledgeable triptan users are regarding their triptan, how much education occurs when triptans are prescribed, and the imp...


    pub_type: 杂志文章,多中心研究


    authors: Baron EP,Markowitz SY,Lettich A,Hastriter E,Lovell B,Kalidas K,Dodick DW,Schwedt TJ,American Headache Society Headache Fellows Research Consortium.

    更新日期:2014-04-01 00:00:00

  • Amitriptyline is effective in chronic but not in episodic tension-type headache: pathogenetic implications.

    abstract::The tricyclic antidepressant, amitriptyline, is an effective drug for the treatment of chronic tension-type headache and for other chronic pain syndromes, but it is also effective in the prophylaxis of an episodic type of headache such as migraine. However, its efficacy in episodic tension-type headache has not yet be...


    pub_type: 杂志文章


    authors: Cerbo R,Barbanti P,Fabbrini G,Pascali MP,Catarci T

    更新日期:1998-06-01 00:00:00

  • Possible Involvement of Hypotension in Postprandial Headache: A Case Series.

    abstract:BACKGROUND:It is commonly known that headaches are induced by intake of specific food, drink, and/or additive. In addition, some patients experience postprandial headache independent of ingestion of specific items. Currently, information on the pathophysiology underlying this particular type of headache is scarce. CAS...


    pub_type: 杂志文章


    authors: Takizawa T,Shibata M,Hiraide T,Seki M,Takahashi S,Suzuki N

    更新日期:2017-10-01 00:00:00

  • Gender, primary headache, and psychological distress.

    abstract::The study compared the psychological symptoms of 26 young men and 65 young women referred to a neurology clinic in northern Israel by their family physicians for medical advice regarding headache. The main findings indicated that the women had more severe psychological symptoms than the men in six subscales, although ...


    pub_type: 杂志文章


    authors: Gilbar O,Bazak Y,Harel Y

    更新日期:1998-01-01 00:00:00

  • Double-blind trial of fluoxetine: chronic daily headache and migraine.

    abstract::This study is the first double-blind placebo-controlled trial of fluoxetine for chronic daily headache (CDH) and migraine. After a one month single-blind baseline on placebo, subjects with CDH (n = 64) and migraine (n = 58) were randomly assigned to a three month trial of fluoxetine (20 mg) or an identical placebo. Fl...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Saper JR,Silberstein SD,Lake AE 3rd,Winters ME

    更新日期:1994-10-01 00:00:00

  • Transcranial Doppler ultrasonographic features during drug withdrawal from drug-induced headache. A transcranial Doppler follow-up study.

    abstract:BACKGROUND:A vascular component in ergotamine-induced headache has been proposed. No study has been carried out to evaluate cerebral hemodynamic changes by means of transcranial Doppler during withdrawal from migraine medication; in particular, ergotamine-containing drugs. METHOD:We examined 21 patients suffering from...


    pub_type: 杂志文章


    authors: Haase CG,Diener HC

    更新日期:1998-10-01 00:00:00

  • Migraine frequency and intensity: relationship with disability and psychological factors.

    abstract:BACKGROUND:Migraine can be disabling, but it varies greatly in frequency and intensity between individuals. It is not clear which clinical features have the greatest impact on a migraineur's quality of life. OBJECTIVE:To determine the influence of headache intensity and frequency on headache-related disability. METHO...


    pub_type: 杂志文章


    authors: Magnusson JE,Becker WJ

    更新日期:2003-11-01 00:00:00

  • Patulous Eustachian tube in spontaneous intracranial hypotension syndrome.

    abstract::A 48-year-old slender woman presented with a rare case of spontaneous intracranial hypotension syndrome manifesting as patulous Eustachian tube. The patient complained of sudden onset of ear fullness and nasal voice as well as typical orthostatic headache. Patulous Eustachian tube was identified by observation of sync...


    pub_type: 杂志文章


    authors: Horikoshi T,Imamura S,Matsuzaki Z,Umeda T,Uchida M,Mitsuka K,Kinouchi H

    更新日期:2007-01-01 00:00:00

  • Statuslike SUNCT in two young women.

    abstract:OBJECTIVE:To describe the statuslike pattern of SUNCT (short-lasting unilateral neuralgiform pain with conjunctival injection and tearing) in two young women. BACKGROUND:SUNCT syndrome is a rare condition characterized by a short-lasting periocular pain associated with marked autonomic symptoms. Twenty-five cases have...


    pub_type: 杂志文章


    authors: Montes E,Alberca R,Lozano P,Franco E,Martínez-Fernández E,Mir P

    更新日期:2001-09-01 00:00:00

  • Elimination of migraine-associated nausea in patients treated with rizatriptan orally disintegrating tablet (ODT): a randomized, double-blind, placebo-controlled study.

    abstract:OBJECTIVE:To confirm the efficacy of rizatriptan 10 mg orally disintegrating tablet (ODT) for the elimination of migraine-associated nausea. BACKGROUND:Pooled studies of rizatriptan analyzing elimination of nausea as a secondary endpoint showed that 65% of rizatriptan patients reported elimination of nausea at 2 hours...


    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Freitag F,Taylor FR,Hamid MA,Rodgers A,Hustad CM,Ramsey KE,Skobieranda F

    更新日期:2008-03-01 00:00:00

  • Does relaxation treatment have differential effects on migraine and tension-type headache in adolescents?

    abstract::The present study evaluated the effects of relaxation treatment in 36 adolescents aged 13 to 18 years (mean +/- SD, 15.4 +/- 1.55 years) suffering from migraine or migraine and tension-type headache as compared with a waiting-list condition group. The subjects rated various characteristics of migraine and tension-type...


    pub_type: 杂志文章


    authors: Fichtel A,Larsson B

    更新日期:2001-03-01 00:00:00

  • Diagnostic criteria for screening headache patients for temporomandibular disorders.

    abstract::Patients with temporomandibular disorders frequently suffer from headache. The purpose of this study was to develop a simple screening exam which would allow the physician to identify headache patients with coexisting temporomandibular disorders. Twenty-eight migraine and 27 tension headache patients were identified b...


    pub_type: 杂志文章


    authors: Schiffman E,Haley D,Baker C,Lindgren B

    更新日期:1995-03-01 00:00:00

  • Migraine-like visual phenomena associated with cerebral venous thrombosis.

    abstract::Two adults presented with new-onset migrainous-type visual disturbances and had angiographically demonstrated filling defects near the torcular Herophili. Neither patient had a visual field deficit nor cerebral computed tomography evidence of an occipital infarction. The association of migraine-like visual phenomena w...


    pub_type: 杂志文章


    authors: Newman DS,Levine SR,Curtis VL,Welch KM

    更新日期:1989-02-01 00:00:00

  • Clinical relevance of efficacy endpoints in OTC headache trials.

    abstract:OBJECTIVE:This analysis evaluates and ranks efficacy endpoints often used in headache trials concerning their clinical relevance in relation to the patient-related criterion "global assessment of overall efficacy" based on data gained in a large trial investigating different over-the-counter drugs in the treatment of h...


    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Pageler L,Diener HC,Pfaffenrath V,Peil H,Aicher B

    更新日期:2009-05-01 00:00:00

  • Successful use of propranolol in migraine associated with electroconvulsive therapy.

    abstract::To date, there have been no reports on the use of propranolol in electroconvulsive therapy (ECT)-induced migraine; we describe a 32-year-old woman who was successfully treated with propranolol for this condition. Over a course of ECT, the patient developed increasingly severe migraine which was refractory to treatment...


    pub_type: 杂志文章


    authors: Hawken ER,Delva NJ,Lawson JS

    更新日期:2001-01-01 00:00:00

  • Individual differences in the subjective experience of pain: new insights into mechanisms and models.

    abstract::Individual differences in pain sensitivity have long remained a perplexing and challenging clinical problem. How can one individual have a sensory experience that is vastly different than that of another, even when they have received similar sensory input? Developing an understanding of such differences and the mechan...


    pub_type: 杂志文章


    authors: Coghill RC

    更新日期:2010-10-01 00:00:00

  • Use of the ICHD-II criteria in the diagnosis of pediatric migraine.

    abstract:OBJECTIVE:To evaluate the sensitivity of the new International Classification of Headache Disorders-2nd edition (ICHD-II) criteria in the diagnosis of childhood migraine and to propose specific criteria for the diagnosis of childhood migraine. BACKGROUND:In 2004, ICHD-II was adopted by the International Headache Socie...


    pub_type: 杂志文章


    authors: Hershey AD,Winner P,Kabbouche MA,Gladstein J,Yonker M,Lewis D,Pearlman E,Linder SL,Rothner AD,Powers SW

    更新日期:2005-11-01 00:00:00

  • Reduced sensitivity of lymphocyte beta-adrenergic receptors in migraine.

    abstract::Cyclic AMP (CAMP) accumulation induced by isoproterenol (IP) and forskolin in intact lymphocytes was determined in 12 patients with migraine and 12 healthy controls. Our data showed that IP CAMP accumulation (8.20 + 1.08 Pmol/million cells) was significantly (P = 0.033) lower than accumulation in the controls (14.39 +...


    pub_type: 杂志文章


    authors: Kuritzky A,Bennet E,Hering R,Ebstein R

    更新日期:1993-04-01 00:00:00

  • Vascular risk in migraineurs: interaction of endothelial and cortical excitability factors.

    abstract:BACKGROUND:Migraine is a common primary headache disorder occurring predominantly in a young, relatively healthy population. RESULTS:There is a growing literature on associations between migraine, especially migraine with aura, and ischemic stroke as well as other vascular events. Migraine as a risk factor for vascula...


    pub_type: 杂志文章,评审


    authors: Murinova N,Krashin DL,Lucas S

    更新日期:2014-03-01 00:00:00

  • Abnormal photoreactivity in ictal migraine: reversal by sumatriptan.

    abstract::The reactivity of posterior cerebral artery (PCA) to light stimulation was studied with transcranial Doppler in 9 migraine patients (5 with aura, 4 without aura) within six hours of the onset of headache (mean 115 +/- 78 minutes). The PCA mean flow velocity was recorded while the patient was in the dark and with the e...


    pub_type: 杂志文章


    authors: Anzola GP,Magoni M,Dalla Volta G

    更新日期:1993-09-01 00:00:00

  • Migraine Prophylaxis and Acute Treatment Patterns Among Commercially Insured Patients in the United States.

    abstract:OBJECTIVES:To describe prophylactic and acute medication treatment patterns, including timing, medication type, and duration of use in migraine patients initiating prophylaxis. BACKGROUND:Patients with migraine can be treated with acute and prophylactic therapies. Current treatment options for migraine prophylaxis are...


    pub_type: 杂志文章


    authors: Woolley JM,Bonafede MM,Maiese BA,Lenz RA

    更新日期:2017-10-01 00:00:00

  • The development of a survey to measure completeness of response to migraine therapy.

    abstract:OBJECTIVE:To assess the psychometric properties of a new patient-reported migraine instrument, the Completeness of Response Survey (CORS), which measures a comprehensive set of factors important to patients' decisions regarding the initiation and continuation of treatment. BACKGROUND:Traditionally, migraine treatments...


    pub_type: 杂志文章,多中心研究


    authors: Coon CD,Fehnel SE,Davis KH,Runken MC,Beach ME,Cady RK

    更新日期:2012-04-01 00:00:00

  • The cerebellum and migraine.

    abstract::Clinical and pathophysiological evidences connect migraine and the cerebellum. Literature on documented cerebellar abnormalities in migraine, however, is relatively sparse. Cerebellar involvement may be observed in 4 types of migraines: in the widespread migraine with aura (MWA) and migraine without aura (MWoA) forms;...


    pub_type: 杂志文章,评审


    authors: Vincent M,Hadjikhani N

    更新日期:2007-06-01 00:00:00

  • Flunarizine versus metoprolol in migraine prophylaxis: a double-blind, randomized parallel group study of efficacy and tolerability.

    abstract::The prophylactic effect of flunarizine and metoprolol was studied in a multi-center randomized, double-blind trial of 149 patients with migraine with or without aura. After a 4-week placebo run-in period, patients were randomly allocated to treatment with flunarizine 10 mg daily or metoprolol 200 mg daily for 16 weeks...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Sørensen PS,Larsen BH,Rasmussen MJ,Kinge E,Iversen H,Alslev T,Nøhr P,Pedersen KK,Schrøder P,Lademann A

    更新日期:1991-11-01 00:00:00

  • A controlled evaluation of the addition of cognitive therapy to a home-based biofeedback and relaxation treatment of vascular headache.

    abstract::Seventy-six patients with vascular (migraine or mixed migraine and tension) headache (HA) participated in a controlled evaluation of a minimal-therapist-contact, largely home-based, treatment program which combined relaxation (R) training with thermal biofeedback (TBF). One group received TBF + R administered in 3 off...


    pub_type: 临床试验,杂志文章


    authors: Blanchard EB,Appelbaum KA,Nicholson NL,Radnitz CL,Morrill B,Michultka D,Kirsch C,Hillhouse J,Dentinger MP

    更新日期:1990-05-01 00:00:00

  • Neuromodulation and Devices in Trigeminal Neuralgia.

    abstract:PREMISE:Trigeminal neuralgia is a severe facial pain disorder that has been studied for decades. Classical trigeminal neuralgia (CTN) is either idiopathic or caused by neurovascular compression. The related painful trigeminal neuropathies are often secondary to other causes, such as multiple sclerosis or trauma. PROBL...


    pub_type: 杂志文章,评审


    authors: Weber K

    更新日期:2017-11-01 00:00:00