Abstract:
BACKGROUND:Previous observational studies reported an increased prevalence of asthma in migraine patients. Whether triptans affect the asthma risk has not yet been explored in an epidemiological study. OBJECTIVE:To estimate the risk of newly diagnosed asthma in patients with a general practitioner-diagnosed migraine in the UK between 1994 and 2001. METHODS:A population-based follow-up study and a nested case-control analysis were conducted using the General Practice Research Database. RESULTS:The study encompassed 51,688 migraineurs and the same number of matched controls. In the follow-up analysis, the relative risk of developing asthma in migraineurs compared with non-migraineurs was 1.3 (95% confidence interval [CI] 1.1-1.4). In the nested case-control analysis, the adjusted odds ratio for asthma in migraineurs overall was 1.17 (95% CI 1.01-1.35), and for those with a recent triptan prescription 1.12 (95% CI 0.65-1.94). CONCLUSION:The risk of developing asthma was not materially altered for patients with a general practitioner-recorded migraine diagnosis, regardless of triptan use.
journal_name
Headachejournal_title
Headacheauthors
Becker C,Brobert GP,Almqvist PM,Johansson S,Jick SS,Meier CRdoi
10.1111/j.1526-4610.2007.01030.xsubject
Has Abstractpub_date
2008-04-01 00:00:00pages
606-10issue
4eissn
0017-8748issn
1526-4610pii
HED1030journal_volume
48pub_type
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