Abstract:
OBJECTIVE:To compare the efficacy of celecoxib for treatment of withdrawal headache vs prednisone in patients with medication overuse headache (MOH). METHODS:In this prospective, double-blind, parallel-group clinical trial, 97 consecutive subjects with MOH were randomized (simple randomization using computer-generated numbers) for treatment with either 400 mg/day celecoxib (for the first 5 days then decreased at a rate of 100 mg every 5 days) or prednisone 75 mg/day orally (for the first 5 days then tapered off every 5 days). Subjects who met the International Headache Society criteria for MOH were included in the trial. The change in headache days and intake of rescue medication were considered as primary outcomes while the change in headache severity defined as a secondary outcome. RESULTS:Patients treated with celecoxib experienced lower headache intensity during the first 3 weeks after withdrawal (after 3 weeks, the median of visual analog scale was 3 for patients in celecoxib group vs 4.5 for prednisone group [P<.001]). However, headache frequency and the need for rescue medication intake were not different between 2 groups. CONCLUSION:During withdrawal in MOH, in order to reduce headache days or rescue medication intake, using either of celecoxib or prednisone as a bridge is not different.
journal_name
Headachejournal_title
Headacheauthors
Taghdiri F,Togha M,Razeghi Jahromi S,Paknejad SMdoi
10.1111/head.12487subject
Has Abstractpub_date
2015-01-01 00:00:00pages
128-35issue
1eissn
0017-8748issn
1526-4610journal_volume
55pub_type
杂志文章,随机对照试验相关文献
HEADACHE文献大全abstract:BACKGROUND:Recent research has shown that affective changes associated with the menstrual cycle may follow diverse patterns, including a classic premenstrual syndrome pattern, as well as the mirror opposite pattern, referred to as a mid-cycle pattern. OBJECTIVE:Test for the presence of a mid-cycle pattern of headaches...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/head.12082
更新日期:2013-06-01 00:00:00
abstract::The treatment of migraine was transformed in 1992 with the introduction of the first triptan-based therapy, subcutaneous (SC) sumatriptan. SC sumatriptan has high efficacy and a rapid onset of action compared with other available triptans and formulations presumably because of its short Tmax, high Cmax, and avoidance ...
journal_title:Headache
pub_type: 杂志文章,评审
doi:10.1111/head.12183
更新日期:2013-09-01 00:00:00
abstract::Long-lasting severe headaches are reported to occur in up to 83% of patients who have undergone resection of acoustic neuroma, especially through a suboccipital approach. These headaches, however, are not well defined. The objective of this study was to assess the frequency and character of new-onset headaches after r...
journal_title:Headache
pub_type: 杂志文章
doi:10.1046/j.1526-4610.1999.3902089.x
更新日期:1999-02-01 00:00:00
abstract::This study examined the relationship between the menstrual cycle, the stress process, and migraines. Women migraineurs (N = 12) and a matched control sample (N = 12) completed a set of questionnaires assessing stress, appraisal, and coping at premenses, menses, and ovulation. In addition, migraineurs completed a month...
journal_title:Headache
pub_type: 杂志文章
doi:10.1046/j.1526-4610.1996.3609531.x
更新日期:1996-10-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to assess the clinical benefits of onabotulinumtoxinA (BOTOX®) treatment on the symptoms of cervical dystonia and the frequency, severity, and associated symptoms of migraine in patients with cervical dystonia and concurrent migraine. BACKGROUND:Botulinum toxin is established ...
journal_title:Headache
pub_type: 临床试验,杂志文章
doi:10.1111/j.1526-4610.2012.02164.x
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVE:To examine the efficacy of L-kynurenine and a novel kynurenic acid derivative on the nitroglycerin-induced calmodulin-dependent protein kinase II alpha (CamKIIalpha) and calcitonin gene-related peptide (CGRP) expression changes in the rat caudal trigeminal nucleus. BACKGROUND:Systemic administration of the n...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.2009.01574.x
更新日期:2010-05-01 00:00:00
abstract::Migraine shares a complex and poorly understood relationship with sleep. Patients consistently report poor sleep prior to migraine attacks and during them, identifying poor sleep as a migraine trigger. However, anecdotally, sleep is reported to serve a therapeutic role in terminating headache. Are the associations bet...
journal_title:Headache
pub_type: 杂志文章,评审
doi:10.1111/head.13358
更新日期:2018-07-01 00:00:00
abstract::The typical symptom of intracranial hypotension syndrome is orthostatic headache. The headache may also be accompanied by neck pain and stiffness, low backache, radicular symptoms, quadriplegia, interscapular pain, nausea/vomiting, and cranial nerve involvement symptoms (hearing and visual problems, face pain and numb...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.2010.01825.x
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:To determine the pain intensity of cluster headache through a large survey by comparing it to other painful disorders. Furthermore, to investigate the relationship between maximal pain, autonomic, and other clinical symptoms, as well as demographic attributes of cluster headache. BACKGROUND:The pain of clust...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/head.14021
更新日期:2020-12-18 00:00:00
abstract::Objective - To briefly describe the history of and available data on anti-calcitonin gene-related peptide (CGRP) therapies for headache. Background - CGRP was proposed as a target for primary headache therapies. Translational research involved moving from delineating the relationships between CGRP and primary headache...
journal_title:Headache
pub_type: 杂志文章,评审
doi:10.1111/head.13379
更新日期:2018-11-01 00:00:00
abstract::A serologically proven case of parainfluenza viral infection was associated with the onset and disappearance of cluster headache. The patient had long-standing migraine that ceased during the cluster headache period and recurred when the latter stopped. Possibly, the virus was neurally transmitted to the trigeminal-au...
journal_title:Headache
pub_type: 杂志文章
doi:10.1046/j.1526-4610.1998.3802132.x
更新日期:1998-02-01 00:00:00
abstract:OBJECTIVE:To assess the acute treatment of pregnant women presenting to a hospital with migraine. BACKGROUND:Migraine is a common problem in pregnancy; however, migraine treatment is challenging in pregnant women for fears of medication teratogenicity and lack of data in this population. To date, no study has directly...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/head.13434
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Transient headache and neurologic deficits with cerebrospinal fluid lymphocytosis (HaNDL) is benign and self-limited, with neurologic deficits including sensory disturbance of one body side, aphasia, nausea/vomiting, weakness, decreased vision, homonymous hemianopsia, photophobia. Acute confusional state can...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/head.13238
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:Ophthalmoplegic migraine (OM) is a rare disorder characterized by recurrent oculomotor nerve palsy in children, following migraine headaches. We report 62 adults, seen consecutively, who developed acute ophthalmoplegia with severe attacks of migraine over a 10-year (1996-2005) period. An overwhelming majority...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.2009.01405.x
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:The buildup time of migraine headaches has not been well delineated in publications to date and we are aware of patients whose migraines last well over 72 hours. More concentration on these factors in the assessment of patients might lead to more appropriate therapeutic choices. METHOD:Prospective ascertain...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.2006.00608.x
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVES:To examine the relationship between migraine and nonmigrainous headache and asthma, hay fever, and chronic bronchitis in a large cross-sectional population-based study. BACKGROUND:Associations between prevalence of migraine and asthma or allergy have been demonstrated in clinic-based and epidemiologic studi...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.2006.00597.x
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVE:To describe a standardized methodology for the performance of peripheral nerve blocks (PNBs) in the treatment of headache disorders. BACKGROUND:PNBs have long been employed in the management of headache disorders, but a wide variety of techniques are utilized in literature reports and clinical practice. MET...
journal_title:Headache
pub_type: 杂志文章,评审
doi:10.1111/head.12053
更新日期:2013-03-01 00:00:00
abstract::In a period of one year (1990) we selected 40 patients suffering from migraine. For an open randomized study there were 2 groups of patients: the first were treated with 10mg of flunarizine per day and the second with 3 mg per day. The patients were treated for 4 months consecutively. There were 11 drop outs (27.5%): ...
journal_title:Headache
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1526-4610.1992.hed3208390.x
更新日期:1992-09-01 00:00:00
abstract::Chronic drug exposure can induce a significant change in neurotransmitter receptor systems and is possibly involved in the pathogenesis of drug-induced neurological disorders. Abuse of analgesics is known to induce deterioration in headache status in patients with primary headaches, especially migraine. To assess the ...
journal_title:Headache
pub_type: 杂志文章
doi:10.1046/j.1526-4610.1998.3807534.x
更新日期:1998-07-01 00:00:00
abstract::Flunarizine is a non-selective calcium antagonist. It distributes preferentially in the adipose tissue and passes the blood brain barrier. Numerous controlled clinical studies have established that flunarizine is efficacious in migraine prophylaxis, including double-blind studies in which the drug was compared with pl...
journal_title:Headache
pub_type: 临床试验,杂志文章,随机对照试验,评审
doi:10.1111/j.1526-4610.1991.hed3106388.x
更新日期:1991-06-01 00:00:00
abstract::Patients with cluster headaches have been reported to have low serum ionized magnesium levels. We examined the possibility that patients with cluster headaches and low ionized magnesium levels may respond to an intravenous infusion of magnesium sulfate. Thirty-eight infusions of magnesium sulfate were given to 22 pati...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.1995.hed3510597.x
更新日期:1995-11-01 00:00:00
abstract::The author reports the use of pregabalin in a patient with glossopharyngeal neuralgia. The patient achieved complete pain relief and tolerated the medication. This is the first published report of the use of this medicine for glossopharyngeal neuralgia. ...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.2006.00543_3.x
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVE:Migraine is associated with several important visual symptoms, during both acute attacks and headache-free intervals. The purpose of this investigation was to use validated vision-related quality of life instruments to assess the effect of migraine on visual quality of life. BACKGROUND:Many migraineurs exper...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/head.13330
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Migraine is a common neurological disorder, ranked among the world's leading causes of years lived with disability by the World Health Organization. The burden of migraine is highest in women of reproductive age. METHODS:We characterized the prevalence, symptoms, and correlates of migraine and other headach...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/head.12206
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:To investigate the impact of coumarin therapy on migraine attack frequency. BACKGROUND:Sporadic case reports and clinical studies have described beneficial effects of coumarin therapy on migraine severity. DESIGN AND METHODS:A retrospective follow-up study based on a prescription database covering a populat...
journal_title:Headache
pub_type: 杂志文章
doi:10.1046/j.1526-4610.2001.01141.x
更新日期:2001-09-01 00:00:00
abstract::Spontaneous intracranial hypotension typically results from spontaneous cerebrospinal fluid (CSF) leak, often at spine level and only rarely from skull base. Once considered rare, it is now diagnosed far more commonly than before and is recognized as an important cause of headaches. CSF leak leads to loss of CSF volum...
journal_title:Headache
pub_type: 杂志文章,评审
doi:10.1111/head.12149
更新日期:2013-07-01 00:00:00
abstract::More than 60 years ago Aristides Leão coined the term spreading depression (SD) to describe a transient "depression" of electrocorticographic activity that lasts up to several minutes and slowly "spreads" in all directions in cortex by way of gray matter contiguity.(1) Today we know that SD is an intrinsic electrophys...
journal_title:Headache
pub_type: 杂志文章,评审
doi:10.1111/j.1526-4610.2010.01647.x
更新日期:2010-04-01 00:00:00
abstract::Exercise, as a method of migraine management has been discussed theoretically and tested empirically. The consensus is that exercise can help to reduce the frequency, intensity and/or duration of migraine attacks. Conversely, there are case studies which, with few exceptions, suggest that periods of exercise can preci...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.1991.hed3109616.x
更新日期:1991-10-01 00:00:00
abstract::Ischemic colitis has not been reported in association with naratriptan therapy. We describe the occurrence of ischemic colitis in a patient who was treated with abortive doses of naratriptan for migraine and was also taking long-term oral contraceptives. Concurrent use of naratriptan and oral contraceptives should pro...
journal_title:Headache
pub_type: 杂志文章
doi:10.1111/j.1526-4610.2005.05077_4.x
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:A recent study conducted in triptan-naive migraine patients showed that tolerability was the second most important attribute of an acute treatment. However, the proportion of patients reporting side effects after any acute treatment may vary with regard to the method of assessment. OBJECTIVES:To contrast tw...
journal_title:Headache
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1526-4610.2004.04191.x
更新日期:2004-11-01 00:00:00