Kynurenate derivative attenuates the nitroglycerin-induced CamKIIα and CGRP expression changes.

abstract：BACKGROUND:In patients with episodic migraine (EM), diffusion tensor imaging (DTI) revealed microstructural white matter alterations in various brain regions related to pain processing. Some of these changes were correlated with migraine duration and attack frequency, suggesting that migraine is a progressive disease w...

journal_title：Headache

authors： Neeb L,Bastian K,Villringer K,Gits HC,Israel H,Reuter U,Fiebach JB

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:A hallmark of migraine is photophobia. In mice, photophobia-like behavior is induced by calcitonin gene-related peptide (CGRP), a neuropeptide known to be a key player in migraine. In this study, we sought to identify sites within the brain from which CGRP could induce photophobia. DESIGN:We focused on the p...

journal_title：Headache

authors： Sowers LP,Wang M,Rea BJ,Taugher RJ,Kuburas A,Kim Y,Wemmie JA,Walker CS,Hay DL,Russo AF

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Variables that are thought to precipitate migraine or tension-type headache episodes in children hitherto have only been studied using retrospective reports. As such, there is little empirical evidence to support the actual predictive association between presumed headache triggers and actual headache occurre...

journal_title：Headache

authors： Connelly M,Miller T,Gerry G,Bickel J

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:To compare, using a within-woman analysis, the severity, duration, and relapse of menstrual vs nonmenstrual episodes of migraine during treatment with usual migraine therapy. BACKGROUND:Studies comparing the clinical characteristics of menstrual and nonmenstrual migraine attacks have yielded conflicting resu...

journal_title：Headache

authors： MacGregor EA,Victor TW,Hu X,Xiang Q,Puenpatom RA,Chen W,Campbell JC

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVES:To report the case of a patient enduring migraine attacks preceded by hallucinatory olfactory symptoms, with characteristics which typically define migraine with aura (MWA). BACKGROUND:MWA accounts for about 30-40% of the total cases of migraine and is almost always preceded by visual disorders; and in rare...

journal_title：Headache

authors： Tiriticco M,Vanotti A,Mantica D,Coppola A

更新日期：2020-11-01 00:00:00

abstract：:Vascular headaches, including migraine, cluster, and migrainous transformation to chronic daily headaches, are disabling. During and shortly after headache intervals, difficulties are reported in concentration, comprehension, and communication, not accounted for by nausea, photophobia, or sonophobia. These interfere w...

journal_title：Headache

authors： Meyer JS,Thornby J,Crawford K,Rauch GM

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:In Ontario, approximately $3.8 billion is spent annually on publicly funded drug programs. The annual growth in Ontario Public Drug Program (OPDP) expenditure has been limited to 1.2% over the course of 3 years. Concurrently, the Ontario Drug Policy Research Network (ODPRN) was appointed to conduct drug clas...

journal_title：Headache

authors： Coyle D,Lee KM,Mamdani M,Sabarre KA,Tingley K

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:To determine (1) the clinical course of a sample of chronic migraine patients with drug overuse 6 and 12 months following in-patient treatment and (2) whether functional impairment, assessed by the Migraine Disability Assessment (MIDAS) questionnaire, improved upon treatment. BACKGROUND:Patients with chronic...

journal_title：Headache

authors： Grazzi L,Andrasik F,D'Amico D,Usai S,Kass S,Bussone G

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:Our study aims to examine factors related to access of triptans among multiple stakeholder groups. BACKGROUND:Triptans are a cornerstone of pain management for the acute treatment of migraine, but actual utilization of triptans is lower than ideal. Initial and continued access to triptans may be an important...

journal_title：Headache

authors： Khan S,Mascarenhas A,Moore JE,Knowles S,Gomes T

更新日期：2015-07-01 00:00:00

abstract：:Magnetic resonance (MR) angiography was performed during and between two spontaneous and untreated attacks in a 24-year old male patient with episodic cluster headache. The ipsilateral ophthalmic artery was observed to be markedly dilated during both attacks. No changes were seen in the internal carotid artery or any ...

journal_title：Headache

authors： Waldenlind E,Ekbom K,Torhall J

更新日期：1993-06-01 00:00:00

abstract：:Genetic mutations of sporadic hemiplegic migraine (SHM) are mostly unknown. SHM pathophysiology relies on cortical spreading depression (CSD), which might be responsible for ischemic brain infarction. Cystic fibrosis (CF) is caused by a monogenic mutation of the chlorine transmembrane conductance regulator (CFTR), pos...

journal_title：Headache

authors： Mancini V,Mastria G,Frantellizzi V,Troiani P,Zampatti S,Carboni S,Giardina E,Campopiano R,Gambardella S,Turchi F,Petolicchio B,Toscano M,Liberatore M,Viganò A,Di Piero V

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:To determine whether patients with vestibular migraine are more likely to suffer from an occipital headache than patients with migraine without vestibular symptoms. BACKGROUND:Vestibular migraine is an underdiagnosed disorder in which migraine is associated with vestibular symptoms. Anatomical evidence and s...

journal_title：Headache

authors： Wattiez AS,O'Shea SA,Ten Eyck P,Sowers LP,Recober A,Russo AF,Fattal D

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Headache diaries are a mainstay of migraine management. While many commercial smartphone applications (apps) have been developed for people with migraine, little is known about how well these apps protect patient information and whether they are secure to use. OBJECTIVE:We sought to assess whether there are...

journal_title：Headache

authors： Minen MT,Stieglitz EJ,Sciortino R,Torous J

更新日期：2018-07-01 00:00:00

abstract：:We report the case of a 73-year-old woman who presented with right VI nerve palsy and homolateral atypical trigeminal neuralgia; standard neuroradiological investigation of orbital/retroorbital regions and intracranial arteries excluded the most commonly demonstrable underlying causes while brain magnetic resonance (T...

journal_title：Headache

authors： Clerici AM,Merlo P,Rognone F,Noce M,Rognone E,Bono G

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Many children suffering from chronic headache and migraine present with comorbid functional disability, including physical, social, emotional, and academic activities. For children severely impaired by headache, intensive interdisciplinary pain rehabilitation treatment (IIPT) can improve functioning. However...

journal_title：Headache

authors： Benore E,Webster EE,Wang L,Banez G

更新日期：2018-11-01 00:00:00

abstract：:Subarachnoid hemorrhage as a complication of acupuncture has been reported in only a few cases. We report another case and discuss the implications of subarachnoid hemorrhage following acupuncture. Although acupuncture has traditionally been thought to be relatively safe, physicians should be aware that it may be a ca...

journal_title：Headache

authors： Tsukazaki Y,Inagaki T,Yamanouchi Y,Kawamoto K,Oka N

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVES:The aim of our study is to determine the prevalence of migraine in Provincial Center of Edirne. METHODS:A systematic random sample of 386 inhabitants over 14 years old were interviewed face to face. Diagnosis of migraine was based on the International Headache Society (IHS) classification. RESULTS:Migraine...

journal_title：Headache

authors： Celik Y,Ekuklu G,Tokuç B,Utku U

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Medication-overuse headache (MOH) refers to headache attributed to excessive use of acute medications. The role of personality needs studies to explain the shifting from drug use to drug abuse. The main aim of this study is to study personality, according to Minnesota Multiphasic Personality Inventory, compa...

journal_title：Headache

authors： Galli F,Pozzi G,Frustaci A,Allena M,Anastasi S,Chirumbolo A,Ghiotto N,Guidetti V,Matarrese A,Nappi G,Pazzi S,Quartesan R,Sances G,Tassorelli C

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the geographic location of the United Council for Neurologic Subspecialties (UCNS)-certified headache subspecialists as compared with ratios of expected migraine and chronic migraine populations in the United States. BACKGROUND:The UCNS is a professional medical organization that accredits fellow...

journal_title：Headache

authors： Mauser ED,Rosen NL

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:To describe a short-term "real-life" longitudinal evolution of migraine course, quality of life, and disability in a sample of patients attending to a specialty center and to evaluate the association between the changes in patient-reported outcomes, number of reported headaches, their severity, and treatment ...

journal_title：Headache

authors： Raggi A,Leonardi M,Bussone G,D'Amico D

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVES:To estimate the 1-year prevalence of headache, its repercussion and its association with the academic performance of university students. METHODS:Cross-sectional study. Three hundred eighty students were randomly selected out of the 1718, 90.5% of them were interviewed. A semi-structured interview, the Head...

journal_title：Headache

authors： Souza-e-Silva HR,Rocha-Filho PA

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the prevalence, demographic, clinical features, and possible risk factors for hemodialysis headache (HDH). BACKGROUND:HDH has been recognized for many years, but the pathophysiology of this condition is not known. High arterial blood pressure, decreased serum osmolality,...

journal_title：Headache

authors： Goksel BK,Torun D,Karaca S,Karatas M,Tan M,Sezgin N,Benli S,Sezer S,Ozdemir N

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVES:The aim of our study was to investigate the prevalence of sleep disorders in chronic headache patients and to evaluate the role of psychiatric comorbidity in the association between chronic headache and sleep complaints. BACKGROUND:The prevalence of sleep disorders in chronic headache has been seldom invest...

journal_title：Headache

authors： Sancisi E,Cevoli S,Vignatelli L,Nicodemo M,Pierangeli G,Zanigni S,Grimaldi D,Cortelli P,Montagna P

更新日期：2010-10-01 00:00:00

abstract：:The symptoms of migraine are non-specific and can be present in many other primary and secondary headache disorders, which are reviewed. Even experienced headache specialists may be challenged at times when diagnosing what appears to be first or worst, new type, migraine status, and chronic migraine. ...

journal_title：Headache

authors： Evans RW

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:The role of diet in the management of the headache patient is a controversial topic in the headache field. OBJECTIVES:To review the evidence supporting the hypothesis that specific foods or ingredients within foods and beverages trigger attacks of headache and/or migraine and to discuss the use of eliminati...

journal_title：Headache

authors： Martin VT,Vij B

更新日期：2016-10-01 00:00:00

abstract：:Previously called "childhood periodic syndromes that are commonly precursors of migraine" in International Headache Classification of Headache Disorders (ICHD)-II, these disorders were renamed "episodic syndromes that may be associated with migraine" in ICHD-III beta. The specific disorders reviewed in this article in...

journal_title：Headache

authors： Gelfand AA

更新日期：2015-11-01 00:00:00

abstract：:The aim of this study was to clarify a possible relationship between pollution and worsening of headache in the industrial city of Turin. From October 1992 to June 1993, we examined a group of 32 patients suffering from various headache types. During these months, they kept a daily record of their headaches and associ...

journal_title：Headache

authors： Nattero G,Enrico A

更新日期：1996-04-01 00:00:00

abstract：OBJECTIVE:To explore the effects of olmesartan on frequency and severity of migraine attacks in patients with comorbid hypertension and prehypertension. BACKGROUND:A randomized, double-blind, placebo-controlled, crossover study with a total of 60 patients has demonstrated the efficacy and safety of the angiotensin II ...

journal_title：Headache

authors： Charles JA,Jotkowitz S,Byrd LH

更新日期：2006-03-01 00:00:00

abstract：:In order to obtain data regarding peripheral levels of beta-endorphin in head pain syndromes, we evaluated the plasma beta-endorphin secretory pattern in 12 adult male patients suffering from cluster headache. Blood samples were drawn every 2 hours for a 24-hour period, and in addition at 30-minute intervals for 120 m...

journal_title：Headache

authors： Franceschini R,Leandri M,Gianelli MV,Cataldi A,Bruno E,Rolandi E,Barreca T

更新日期：1996-11-01 00:00:00

abstract：:This is a case report of a 15-year-old boy who developed benign intracranial hypertension after 3 weeks of levofloxacin intake. The headache, diplopia, and papilledema resolved within a week after levofloxacin was withdrawn. Physicians must be aware that quinolone antibiotics can potentially cause intracranial hyperte...

journal_title：Headache

authors： Lardizabal DV

更新日期：2009-02-01 00:00:00