Low dose flunarizine in the prophylaxis of migraine.

Abstract:

:In a period of one year (1990) we selected 40 patients suffering from migraine. For an open randomized study there were 2 groups of patients: the first were treated with 10mg of flunarizine per day and the second with 3 mg per day. The patients were treated for 4 months consecutively. There were 11 drop outs (27.5%): nine for poor compliance and 2 due to side effects. The efficacy of flunarizine in the prophylaxis of migraine was essentially identical in the two dosage groups while the incidence of side effects was considerably reduced in the patients treated with the lower dose.

journal_name

Headache

journal_title

Headache

authors

Bassi P,Brunati L,Rapuzzi B,Alberti E,Mangoni A

doi

10.1111/j.1526-4610.1992.hed3208390.x

keywords:

subject

Has Abstract

pub_date

1992-09-01 00:00:00

pages

390-2

issue

8

eissn

0017-8748

issn

1526-4610

journal_volume

32

pub_type

临床试验,杂志文章,随机对照试验

相关文献

HEADACHE文献大全
  • Differences in the personality profile of medication-overuse headache sufferers and drug addict patients: a comparative study using MMPI-2.

    abstract:BACKGROUND:Medication-overuse headache (MOH) refers to headache attributed to excessive use of acute medications. The role of personality needs studies to explain the shifting from drug use to drug abuse. The main aim of this study is to study personality, according to Minnesota Multiphasic Personality Inventory, compa...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2011.01978.x

    authors: Galli F,Pozzi G,Frustaci A,Allena M,Anastasi S,Chirumbolo A,Ghiotto N,Guidetti V,Matarrese A,Nappi G,Pazzi S,Quartesan R,Sances G,Tassorelli C

    更新日期:2011-09-01 00:00:00

  • Cushing syndrome induced by serial occipital nerve blocks containing corticosteroids.

    abstract::A patient with chronic daily headaches developed overt signs of Cushing syndrome during treatment with serial occipital nerve block injections. Investigation demonstrated an exogenous source of corticosteroids as the cause of the Cushing syndrome in this patient, thus, implicating the corticosteroid component of the o...

    journal_title:Headache

    pub_type: 杂志文章

    doi:

    authors: Lavin PJ,Workman R

    更新日期:2001-10-01 00:00:00

  • Intravenous Endothelin-1 Infusion Does Not Induce Aura or Headache in Migraine Patients With Aura.

    abstract:OBJECTIVE:To investigate whether intravenously infused provokes migraine aura and migraine headache in migraine patients with aura. BACKGROUND:Migraine with aura has been associated with endothelial dysfunction and increased stroke risk. The initiating mechanism of migraine aura symptoms is not known. Experimental pro...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.13753

    authors: Hougaard A,Younis S,Iljazi A,Sugimoto K,Ayata C,Ashina M

    更新日期:2020-04-01 00:00:00

  • Misdiagnosis of Spontaneous Intracranial Hypotension as a Risk Factor for Subdural Hematoma.

    abstract:OBJECTIVE:This study aimed to evaluate the association between misdiagnosis of spontaneous intracranial hypotension (SIH) and subdural hematoma development. BACKGROUND:Although SIH is more prevalent than expected and causes potentially life-threatening complications including subdural hematoma (SDH), the association b...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.13132

    authors: Kim YJ,Cho HY,Seo DW,Sohn CH,Ahn S,Lee YS,Kim WY,Lim KS

    更新日期:2017-11-01 00:00:00

  • Association of RAMP1 rs7590387 with the risk of migraine transformation into medication overuse headache.

    abstract:OBJECTIVES/BACKGROUND:We herein investigated the role of polymorphisms in calcitonin gene-related peptide (CGRP)-related genes looking at the association of rs3781719 (T > C) in the calcitonin gene-related polypeptide-alpha (CALCA) gene and of rs3754701 (T > A) and rs7590387 (C > G) at the receptor activity modifying 1...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.12559

    authors: Cargnin S,Pautasso C,Viana M,Sances G,Mittino D,Cantello R,Tassorelli C,Nappi G,Terrazzino S

    更新日期:2015-05-01 00:00:00

  • The prevalence of headache in Greece: correlations to latitude and climatological factors.

    abstract::A questionnaire study on headaches, using a door-to-door survey, was carried out in a representative sample of the general Greek population, including 1737 men and 1764 women, from 15 to 75 years of age. The parameters evaluated included age, sex, education, socioeconomic status, region of domicile, frequency of heada...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.1996.3603168.x

    authors: Mitsikostas DD,Tsaklakidou D,Athanasiadis N,Thomas A

    更新日期:1996-03-01 00:00:00

  • Triptans--why once?

    abstract:OBJECTIVE:To evaluate triptan use patterns in a large Israeli HMO district. BACKGROUND:Triptans, 5HT(1B/1D) agonists, provide an effective and safe relief of headache and accompanying symptoms during an acute migraine attack. METHOD:We retrospectively reviewed the computerized prescription filling data of 1498 patien...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2006.00435.x

    authors: Ifergane G,Wirguin I,Shvartzman P

    更新日期:2006-09-01 00:00:00

  • Pathophysiology of chronic migraine and mode of action of preventive medications.

    abstract::Evidence has accumulated in recent years indicating structural, physiologic, and biochemical alterations in the brain of patients with chronic migraine (CM). Altered pharmacologic responses to opioids and other analgesics have also been reported. Structural or morphologic changes include reduced cortical gray matter o...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2011.01955.x

    authors: Mathew NT

    更新日期:2011-07-01 00:00:00

  • Periaqueductal gray matter dysfunction in migraine: cause or the burden of illness?

    abstract:OBJECTIVE:The periaqueductal gray matter (PAG) is at the center of a powerful descending antinociceptive neuronal network. We studied iron homeostasis in the PAG as an indicator of function in patients with episodic migraine (EM) between attacks and patients with chronic daily headache (CDH) during headache. High-resol...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.2001.041007629.x

    authors: Welch KM,Nagesh V,Aurora SK,Gelman N

    更新日期:2001-07-01 00:00:00

  • Plasticity of 5-HT serotonin receptor in patients with analgesic-induced transformed migraine.

    abstract::Chronic drug exposure can induce a significant change in neurotransmitter receptor systems and is possibly involved in the pathogenesis of drug-induced neurological disorders. Abuse of analgesics is known to induce deterioration in headache status in patients with primary headaches, especially migraine. To assess the ...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.1998.3807534.x

    authors: Srikiatkhachorn A,Puangniyom S,Govitrapong P

    更新日期:1998-07-01 00:00:00

  • Calcitonin gene-related peptide (CGRP) and migraine current understanding and state of development.

    abstract::Calcitonin gene-related peptide (CGRP) is a ubiquitous neuropeptide found at the very centers of the migraine process, both centrally and peripherally. It has been under careful study for approximately 25 years. Several CGRP-receptor antagonists are being evaluated for acute treatment of episodic migraine. Three monoc...

    journal_title:Headache

    pub_type: 杂志文章,评审

    doi:10.1111/head.12179

    authors: Bigal ME,Walter S,Rapoport AM

    更新日期:2013-09-01 00:00:00

  • Stimulation of Posterior Thalamic Nuclei Induces Photophobic Behavior in Mice.

    abstract:OBJECTIVE:A hallmark of migraine is photophobia. In mice, photophobia-like behavior is induced by calcitonin gene-related peptide (CGRP), a neuropeptide known to be a key player in migraine. In this study, we sought to identify sites within the brain from which CGRP could induce photophobia. DESIGN:We focused on the p...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.13917

    authors: Sowers LP,Wang M,Rea BJ,Taugher RJ,Kuburas A,Kim Y,Wemmie JA,Walker CS,Hay DL,Russo AF

    更新日期:2020-10-01 00:00:00

  • Molecular pharmacology of topiramate: managing seizures and preventing migraine.

    abstract::Topiramate is a neuromodulatory compound with stabilizing properties that was initially introduced for the management of partial seizures. Topiramate has been demonstrated to modify several receptor-gated and voltage-sensitive ion channels, including voltage-activated Na+ and Ca2+ channels and non-NMDA receptors. Thes...

    journal_title:Headache

    pub_type: 杂志文章,评审

    doi:10.1111/j.1526-4610.2005.4501006.x

    authors: White HS

    更新日期:2005-04-01 00:00:00

  • Transient Global Amnesia Triggered by Migraine in a French Tertiary-Care Center: An 11-Year Retrospective Analysis.

    abstract:OBJECTIVE:The etiology of transient global amnesia (TGA) remains unclear, and flow disturbances in the mesial temporal lobes secondary to venous congestion have been proposed as a potential cause. The occurrence of TGA during a migraine attack is a rare condition. METHODS:This 11-year retrospective study in one French...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.12545

    authors: Donnet A

    更新日期:2015-06-01 00:00:00

  • Headache and sferics.

    abstract::Many patients with migraine believe weather is a trigger for their headaches. The objective of this study was to determine if very low frequency sferics, pulse-shaped electromagnetic fields originating from atmospheric discharges (lightning), are precipitating factors. The occurrence of sferics impulses is characteriz...

    journal_title:Headache

    pub_type: 杂志文章

    doi:

    authors: Vaitl D,Propson N,Stark R,Walter B,Schienle A

    更新日期:2001-10-01 00:00:00

  • Persistent migraine aura: new cases, a literature review, and ideas about pathophysiology.

    abstract:BACKGROUND:Persistent migraine aura without infarction (PMA) is a rare condition that is defined as an aura that lasts longer than 1 week in absence of infarction. Two types of PMA have been distinguished, notably persistent primary visual disturbance (PPVD) and typical aura (TA). OBJECTIVES:This case-based review art...

    journal_title:Headache

    pub_type: 杂志文章,评审

    doi:10.1111/head.12392

    authors: Thissen S,Vos IG,Schreuder TH,Schreurs WM,Postma LA,Koehler PJ

    更新日期:2014-09-01 00:00:00

  • Olfaction in migraineurs.

    abstract::Many investigators have described olfactory dysfunction among migraineurs. Olfactory stimuli can precipitate migraine, and olfactory hallucinations can occur as auras of migraines or as part of the symptom complex. Despite many reports linking olfactory phenomena and migraine, no evaluations of the olfactory abilities...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.1992.hed3205233.x

    authors: Hirsch AR

    更新日期:1992-05-01 00:00:00

  • Information about migraine disability influences physicians' perceptions of illness severity and treatment needs.

    abstract:OBJECTIVE:To assess physician-patient communication about headache-related disability and to evaluate the influence of information about disability on physicians' perceptions of illness severity and the treatment needs of migraineurs. BACKGROUND:Evidence suggests that migraine is suboptimally treated in clinical pract...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.2001.111006343.x

    authors: Holmes WF,MacGregor EA,Sawyer JP,Lipton RB

    更新日期:2001-04-01 00:00:00

  • Glossopharyngeal neuralgia responding to pregabalin.

    abstract::The author reports the use of pregabalin in a patient with glossopharyngeal neuralgia. The patient achieved complete pain relief and tolerated the medication. This is the first published report of the use of this medicine for glossopharyngeal neuralgia. ...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2006.00543_3.x

    authors: Kitchener JM

    更新日期:2006-09-01 00:00:00

  • A controlled evaluation of the addition of cognitive therapy to a home-based biofeedback and relaxation treatment of vascular headache.

    abstract::Seventy-six patients with vascular (migraine or mixed migraine and tension) headache (HA) participated in a controlled evaluation of a minimal-therapist-contact, largely home-based, treatment program which combined relaxation (R) training with thermal biofeedback (TBF). One group received TBF + R administered in 3 off...

    journal_title:Headache

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1526-4610.1990.hed3006371.x

    authors: Blanchard EB,Appelbaum KA,Nicholson NL,Radnitz CL,Morrill B,Michultka D,Kirsch C,Hillhouse J,Dentinger MP

    更新日期:1990-05-01 00:00:00

  • A review of mechanisms of response to pain therapy: why voodoo works.

    abstract::A person's response to pain treatment may be due to factors other than the direct effect of analgesics. Amelioration of pain is often associated with modalities that appear to make no scientific sense. This review outlines the mechanisms of pain amelioration other than that by medication. These mechanisms help to expl...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.2002.02155.x

    authors: Solomon S

    更新日期:2002-07-01 00:00:00

  • The cerebellum and migraine.

    abstract::Clinical and pathophysiological evidences connect migraine and the cerebellum. Literature on documented cerebellar abnormalities in migraine, however, is relatively sparse. Cerebellar involvement may be observed in 4 types of migraines: in the widespread migraine with aura (MWA) and migraine without aura (MWoA) forms;...

    journal_title:Headache

    pub_type: 杂志文章,评审

    doi:10.1111/j.1526-4610.2006.00715.x

    authors: Vincent M,Hadjikhani N

    更新日期:2007-06-01 00:00:00

  • Low brain magnesium in migraine.

    abstract::Brain magnesium was measured in migraine patients and control subjects using in vivo 31-Phosphorus Nuclear Magnetic Resonance Spectroscopy. pMg and pH were calculated from the chemical shifts between Pi, PCr and ATP signals. Magnesium levels were low during a migraine attack without changes in pH. We hypothesize that ...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.1989.hed2909590.x

    authors: Ramadan NM,Halvorson H,Vande-Linde A,Levine SR,Helpern JA,Welch KM

    更新日期:1989-10-01 00:00:00

  • Privacy Issues in Smartphone Applications: An Analysis of Headache/Migraine Applications.

    abstract:BACKGROUND:Headache diaries are a mainstay of migraine management. While many commercial smartphone applications (apps) have been developed for people with migraine, little is known about how well these apps protect patient information and whether they are secure to use. OBJECTIVE:We sought to assess whether there are...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.13341

    authors: Minen MT,Stieglitz EJ,Sciortino R,Torous J

    更新日期:2018-07-01 00:00:00

  • Migraine Care Challenges and Strategies in US Uninsured and Underinsured Adults: A Narrative Review, Part 1.

    abstract:OBJECTIVE:To review the scope of the problem facing individuals with migraine who are under- or uninsured. In this first of a 2-part narrative review, we will explore migraine epidemiology and the challenges that face this vulnerable population. BACKGROUND:Implementation of the Affordable Care Act has improved access ...

    journal_title:Headache

    pub_type: 杂志文章,评审

    doi:10.1111/head.13286

    authors: Charleston L 4th,Royce J,Monteith TS,Broner SW,O'Brien HL,Manrriquez SL,Robbins MS

    更新日期:2018-04-01 00:00:00

  • Statuslike SUNCT in two young women.

    abstract:OBJECTIVE:To describe the statuslike pattern of SUNCT (short-lasting unilateral neuralgiform pain with conjunctival injection and tearing) in two young women. BACKGROUND:SUNCT syndrome is a rare condition characterized by a short-lasting periocular pain associated with marked autonomic symptoms. Twenty-five cases have...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.2001.01151.x

    authors: Montes E,Alberca R,Lozano P,Franco E,Martínez-Fernández E,Mir P

    更新日期:2001-09-01 00:00:00

  • Efficacy and tolerability of zolmitriptan nasal spray for the treatment of acute migraine in adolescents: Results of a randomized, double-blind, multi-center, parallel-group study (TEENZ).

    abstract:OBJECTIVE:The primary objective of the TEENZ Study (NCT01211145) was to assess the efficacy of zolmitriptan nasal spray in the acute treatment of adolescent migraine patients (ages 12 to 17 years), as measured by the primary outcome variable of pain-free status at 2 hours post-treatment. METHODS:This randomized, doubl...

    journal_title:Headache

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1111/head.12859

    authors: Winner P,Farkas V,Štillová H,Woodruff B,Liss C,Lillieborg S,Raines S,TEENZ Study Group.

    更新日期:2016-07-01 00:00:00

  • Reappraising the Tolosa-Hunt Syndrome Diagnostic Criteria: A Case Series.

    abstract:INTRODUCTION:Tolosa-Hunt syndrome (THS), a condition characterized by painful ophthalmoplegia and accompanied by cranial nerve palsies, remains as a diagnosis of exclusion. Nevertheless, the 3rd Edition of the International Classification of Headache Disorders (ICHD) has refined its diagnostic criteria to require the d...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.13692

    authors: Mullen E,Rutland JW,Green MW,Bederson J,Shrivastava R

    更新日期:2020-01-01 00:00:00

  • Multicenter prospective evaluation of proposed pediatric migraine revisions to the IHS criteria. Pediatric Headache Committee of the American Association for the Study of Headache.

    abstract::Eighty-eight children and adolescents were prospectively evaluated at eight specialty clinics comparing the diagnostic criteria of the International Headache Society (IHS) and the proposed revised (IHS-R) classification to the clinical diagnosis. The proposed revisions to the IHS classification for pediatric migraine ...

    journal_title:Headache

    pub_type: 杂志文章,多中心研究

    doi:10.1046/j.1526-4610.1997.3709545.x

    authors: Winner P,Wasiewski W,Gladstein J,Linder S

    更新日期:1997-10-01 00:00:00

  • Chronic tension-type headache, mood depression and serotonin: therapeutic effects of fluvoxamine and mianserine.

    abstract::Forty out-patients affected by chronic tension-type headache were selected according to the diagnostic criteria of International Headache Society (IHS) Headache Classification Committee. In a controlled trial patients received placebo for a four-week baseline period, then they were randomized in double-blind fashion t...

    journal_title:Headache

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1526-4610.1994.hed3401044.x

    authors: Manna V,Bolino F,Di Cicco L

    更新日期:1994-01-01 00:00:00