Olfaction in migraineurs.

Abstract:

:Many investigators have described olfactory dysfunction among migraineurs. Olfactory stimuli can precipitate migraine, and olfactory hallucinations can occur as auras of migraines or as part of the symptom complex. Despite many reports linking olfactory phenomena and migraine, no evaluations of the olfactory abilities of migraineurs have been documented. To begin such assessments, sixty-seven consecutive migraine patients were given Pyridine odor threshold tests. Twelve of them (18%) scored as hyposmic or anosmic. In comparison, 1% of the general population of the U.S. is hyposmic or anosmic. Aside from possible diagnostic or methodological error, several possibilities may account for our result: migraine may induce olfactory pathology; olfactory pathology may induce migraine, or; a common pathogen may induce both olfactory dysfunction and migraine. The association of migraine with the emotional component of the limbic system has long been recognized, and our results strengthen its association with the olfactory component as well. Headache patients should be tested for olfactory loss and warned of such risks as inability to detect gas leaks and spoiled food.

journal_name

Headache

journal_title

Headache

authors

Hirsch AR

doi

10.1111/j.1526-4610.1992.hed3205233.x

keywords:

subject

Has Abstract

pub_date

1992-05-01 00:00:00

pages

233-6

issue

5

eissn

0017-8748

issn

1526-4610

journal_volume

32

pub_type

杂志文章

相关文献

HEADACHE文献大全
  • The relationship between stress, headache, and the menstrual cycle in young female migraineurs.

    abstract::This study examined the relationship between the menstrual cycle, the stress process, and migraines. Women migraineurs (N = 12) and a matched control sample (N = 12) completed a set of questionnaires assessing stress, appraisal, and coping at premenses, menses, and ovulation. In addition, migraineurs completed a month...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.1996.3609531.x

    authors: Holm JE,Bury L,Suda KT

    更新日期:1996-10-01 00:00:00

  • The relationship between homocysteine and genes of folate-related enzymes in migraine patients.

    abstract:BACKGROUND:It has been suggested that homocysteine (Hcy) and the 5'-10'-methylenetetrahydrofolate reductase (MTHFR) C677T variant are implicated in the pathogenesis of migraine. Homocysteine has the potential to damage endothelium and accelerate atherosclerosis. Genetic factors such as the MTHFR C677T polymorphism, and...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2009.01484.x

    authors: Oterino A,Toriello M,Valle N,Castillo J,Alonso-Arranz A,Bravo Y,Ruiz-Alegria C,Quintela E,Pascual J

    更新日期:2010-01-01 00:00:00

  • Occipital lobe tumor presenting as migraine with typical aura.

    abstract::We report the case of a 60-year-old woman in whom migraine with typical aura heralded the presence of an occipital lobe tumor. Her headache was characterized by recurrent episodes of visual aura confined to the left visual field followed by right hemicranial throbbing headaches accompanied by nausea, photophobia, and ...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.1996.3601049.x

    authors: Verma A,Rosenfeld V,Forteza A,Sharma KR

    更新日期:1996-01-01 00:00:00

  • Precipitating and aggravating factors of migraine versus tension-type headache.

    abstract:OBJECTIVE:We conducted the present study to determine whether there are headache precipitating and aggravating factors that differentiate migraine from tension-type headache and headache precipitating and aggravating factors that differentiate tension-type headache from migraine. METHODS:We interviewed 38 patients wit...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.2001.041006554.x

    authors: Spierings EL,Ranke AH,Honkoop PC

    更新日期:2001-06-01 00:00:00

  • Migraine Prophylaxis and Acute Treatment Patterns Among Commercially Insured Patients in the United States.

    abstract:OBJECTIVES:To describe prophylactic and acute medication treatment patterns, including timing, medication type, and duration of use in migraine patients initiating prophylaxis. BACKGROUND:Patients with migraine can be treated with acute and prophylactic therapies. Current treatment options for migraine prophylaxis are...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.13157

    authors: Woolley JM,Bonafede MM,Maiese BA,Lenz RA

    更新日期:2017-10-01 00:00:00

  • Development and validation of the Migraine-Specific Quality of Life Questionnaire.

    abstract::This paper describes the development and validation of a migraine-specific quality-of-life instrument that is capable of measuring health-related quality-of-life impairments attributed to migraine. Item selection, item reduction, and pretesting and finalization of items during the instrument development phase resulted...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.1998.3804295.x

    authors: Jhingran P,Osterhaus JT,Miller DW,Lee JT,Kirchdoerfer L

    更新日期:1998-04-01 00:00:00

  • Patients with chronic tension-type headache demonstrate increased mechano-sensitivity of the supra-orbital nerve.

    abstract:OBJECTIVE:This study aimed to establish whether increased sensitivity to mechanical stimuli is present in neural tissues in chronic tension-type headache (CTTH). BACKGROUND:Muscle hyperalgesia is a common finding in CTTH. No previous studies have investigated the sensitivity of peripheral nerves in patients with CTTH....

    journal_title:Headache

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1526-4610.2008.00856.x

    authors: Fernández-de-Las-Peñas C,Coppieters MW,Cuadrado ML,Pareja JA

    更新日期:2008-04-01 00:00:00

  • Thermographic findings in cranio-facial pain.

    abstract::This work assesses the differences in the thermographic findings in the craniofacial and neck areas between normal individuals and patients with craniofacial pain or headache, and investigates the influence of muscle contraction on such findings. Thermographic records were taken in 10 healthy subjects and 47 patients ...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.1990.hed3008497.x

    authors: Mongini F,Caselli C,Macrì V,Tetti C

    更新日期:1990-07-01 00:00:00

  • Acute demyelination mimicking vascular hemicrania.

    abstract::A 29-year-old woman presented with acute hemicrania, trigeminal neuropathy and posterior fossa dysfunction. The admission differential diagnosis included vertebral artery dissection, posterior circulation aneurysm, vascular malformation and brainstem infarction. However, radiographic and CSF studies indicated demyelin...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.1989.hed2907423.x

    authors: Nager BJ,Lanska DJ,Daroff RB

    更新日期:1989-07-01 00:00:00

  • Needle-free subcutaneous sumatriptan (Sumavel DosePro): bioequivalence and ease of use.

    abstract:BACKGROUND:Subcutaneous (s.c.) injection of sumatriptan is currently associated with needle aversion in some patients, and sharps disposal issues. OBJECTIVES:To investigate whether a needle-free system can deliver s.c. sumatriptan. If so, to examine whether needle-free administration is bioequivalent to a 26-gauge nee...

    journal_title:Headache

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1111/j.1526-4610.2009.01530.x

    authors: Brandes JL,Cady RK,Freitag FG,Smith TR,Chandler P,Fox AW,Linn L,Farr SJ

    更新日期:2009-11-01 00:00:00

  • Hemiplegic migraine aura begins with cerebral hypoperfusion: imaging in the acute phase.

    abstract::Imaging studies of spontaneous migraine aura have proved challenging because of the episodic and unpredictable nature of migraine attacks. Two patients with signs of acute ischemic stroke were evaluated for thrombolysis and turned out to suffer from familial hemiplegic migraine. It was possible to record the early pha...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2011.01963.x

    authors: Hansen JM,Schytz HW,Larsen VA,Iversen HK,Ashina M

    更新日期:2011-09-01 00:00:00

  • Headache diary in the diagnosis of childhood migraine.

    abstract::The usefulness of a headache diary in the diagnosis of migraine and in the clarification of migraine symptoms was studied in 145 children. These children belong to a 1-year age cohort of 5356 children that has been followed since birth. The children were enrolled in the present study according to their headache status...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.1997.3704240.x

    authors: Metsähonkala L,Sillanpää M,Tuominen J

    更新日期:1997-04-01 00:00:00

  • Longitudinal Analysis of Patient-Reported Outcomes From an Interdisciplinary Pediatric Pain Rehabilitation Program for Children With Chronic Migraine and Headache.

    abstract:BACKGROUND:Many children suffering from chronic headache and migraine present with comorbid functional disability, including physical, social, emotional, and academic activities. For children severely impaired by headache, intensive interdisciplinary pain rehabilitation treatment (IIPT) can improve functioning. However...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.13389

    authors: Benore E,Webster EE,Wang L,Banez G

    更新日期:2018-11-01 00:00:00

  • Treatment of migraine with rizatriptan: when to take the medication.

    abstract:OBJECTIVE:To assess, in the setting of routine clinical practice, rizatriptan's effectiveness in treating acute migraine at its onset versus in a later phase of the attack. BACKGROUND:Although the efficacy and tolerability of rizatriptan have been well documented in clinical trials, no information is available about t...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.2002.02008.x

    authors: Hu XH,Raskin NH,Cowan R,Markson LE,Berger ML,United States Migraine Study Protocol (USMAP) Group.

    更新日期:2002-01-01 00:00:00

  • New Onset Focal Stabbing Headache Associated With Peripheral Vertigo: A Case Report.

    abstract::We present a novel case of a focal stabbing headache sharing features of primary stabbing headache that started and resolved with the onset and resolution of a course of self-limiting peripheral vertigo. The association of onset and improvement of the stabbing headaches support the trigeminal and vestibular reciprocal...

    journal_title:Headache

    pub_type: 信件

    doi:10.1111/head.13208

    authors: Chan TLH,Kim DD,Becker WJ

    更新日期:2018-01-01 00:00:00

  • Reading problems in adult chronic headache sufferers.

    abstract::In a questionnaire survey we determined the prevalence of problems with reading, at present as well as in the past, in adult chronic headache sufferers as compared with age- and sex-matched controls. The reading problems inquired about were those with reading in general, reading quickly, prolonged reading and reading ...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.1991.hed3104244.x

    authors: Cremins JJ,Spierings EL,Meltzer LJ,Messinger HB,Lebbink J

    更新日期:1991-04-01 00:00:00

  • Fasting headache: a review of the literature and new hypotheses.

    abstract::Headache is a common disorder in the general population. It is often highly debilitating for the people affected and highly costly to society. Although we know much about primary headaches, little is known about secondary headaches which, however,are a frequent occurrence in the general population. A study conducted o...

    journal_title:Headache

    pub_type: 杂志文章,评审

    doi:10.1111/j.1526-4610.2009.01390.x

    authors: Torelli P,Evangelista A,Bini A,Castellini P,Lambru G,Manzoni GC

    更新日期:2009-05-01 00:00:00

  • Evaluation of beta-endorphin secretion in patients suffering from episodic cluster headache.

    abstract::In order to obtain data regarding peripheral levels of beta-endorphin in head pain syndromes, we evaluated the plasma beta-endorphin secretory pattern in 12 adult male patients suffering from cluster headache. Blood samples were drawn every 2 hours for a 24-hour period, and in addition at 30-minute intervals for 120 m...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.1996.3610603.x

    authors: Franceschini R,Leandri M,Gianelli MV,Cataldi A,Bruno E,Rolandi E,Barreca T

    更新日期:1996-11-01 00:00:00

  • Posterior hypothalamic and brainstem activation in hemicrania continua.

    abstract:OBJECTIVE:To determine the brain structures involved in mediating the pain of hemicrania continua using positron emission tomography. BACKGROUND:Hemicrania continua is a strictly unilateral, continuous headache of moderate intensity, with superimposed exacerbations of severe intensity that are accompanied by trigemina...

    journal_title:Headache

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1526-4610.2004.04141.x

    authors: Matharu MS,Cohen AS,McGonigle DJ,Ward N,Frackowiak RS,Goadsby PJ

    更新日期:2004-09-01 00:00:00

  • Circumstances of onset of chronic headache in patients attending a specialty practice.

    abstract::In a data base of 1013 patients with chronic headache, 44.1% reported the onset of headaches before the age of 20 (preadult-onset headache) and 55.9% at or after that age (adult-onset headache). Circumstances of headache onset were mentioned significantly more frequently in the latter than in the former group (8.5% ve...

    journal_title:Headache

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1526-4610.1999.3905317.x

    authors: Karpouzis KM,Spierings EL

    更新日期:1999-05-01 00:00:00

  • Valsalva-induced cluster: a new subtype of cluster headache.

    abstract::We report the case of a man who suffered from Valsalva-induced cluster headaches. The headaches deviated from classic cluster in that they were solely induced by activity involving the Valsalva maneuver, such as coughing and sneezing, and never occurred spontaneously. The attacks were prevented by treatment with indom...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.2002.02088.x

    authors: Ko J,Rozen TD

    更新日期:2002-04-01 00:00:00

  • Reversible cognitive decline accompanies migraine and cluster headaches.

    abstract::Vascular headaches, including migraine, cluster, and migrainous transformation to chronic daily headaches, are disabling. During and shortly after headache intervals, difficulties are reported in concentration, comprehension, and communication, not accounted for by nausea, photophobia, or sonophobia. These interfere w...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.2000.040008638.x

    authors: Meyer JS,Thornby J,Crawford K,Rauch GM

    更新日期:2000-09-01 00:00:00

  • The Case of the Woman Who Did Never Dare to Fly: Headache Attributed to Imbalance Between Intrasinusal and External Air Pressure.

    abstract:BACKGROUND:A new form of headache, Headache attributed to aeroplane travel (AH), has been recognized within the International Classification of Headache Disorders 3 beta (ICHD-3beta). In 8 out of 85 AH cases we identified the coexistence of a headache with identical features of AH, but appearing during the rapid descen...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.12766

    authors: Mainardi F,Maggioni F,Zanchin G

    更新日期:2016-02-01 00:00:00

  • Individual differences in the subjective experience of pain: new insights into mechanisms and models.

    abstract::Individual differences in pain sensitivity have long remained a perplexing and challenging clinical problem. How can one individual have a sensory experience that is vastly different than that of another, even when they have received similar sensory input? Developing an understanding of such differences and the mechan...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2010.01763.x

    authors: Coghill RC

    更新日期:2010-10-01 00:00:00

  • Funding of research on headache disorders by the National Institutes of Health.

    abstract:BACKGROUND:Despite the high level of individual and societal burden resulting from headache disorders, the National Institutes of Health (NIH) has funded relatively little research on these disorders. OBJECTIVE:The objective of this study was to define current patterns of NIH funding of research on headache disorders....

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2008.01323.x

    authors: Schwedt TJ,Shapiro RE

    更新日期:2009-02-01 00:00:00

  • MRI angiography of a patient before and during alcohol-induced cluster headache.

    abstract::A 25-year-old man, subject to bouts of left supraorbital cluster headache on an annual basis over the previous 8 years, volunteered for MRI angiography during an active period. Studies were conducted before and during a typical cluster headache attack induced by alcohol. MRI angiography failed to show dilatation of th...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.1994.hed3408463.x

    authors: Somerville B

    更新日期:1994-09-01 00:00:00

  • Information about migraine disability influences physicians' perceptions of illness severity and treatment needs.

    abstract:OBJECTIVE:To assess physician-patient communication about headache-related disability and to evaluate the influence of information about disability on physicians' perceptions of illness severity and the treatment needs of migraineurs. BACKGROUND:Evidence suggests that migraine is suboptimally treated in clinical pract...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1046/j.1526-4610.2001.111006343.x

    authors: Holmes WF,MacGregor EA,Sawyer JP,Lipton RB

    更新日期:2001-04-01 00:00:00

  • The role of cardiovascular screening in headache patients.

    abstract::There have been associations demonstrated between migraine and ischemic stroke and heart disease. Additionally, headache patients have increased cardiovascular risk factors. This article reviews available data supporting these concerns and answers the following questions: 1) Does the association between migraine and c...

    journal_title:Headache

    pub_type: 杂志文章,评审

    doi:10.1111/j.1526-4610.2010.01839.x

    authors: Kirkham KE,Colon RJ,Solomon GD

    更新日期:2011-02-01 00:00:00

  • Circadian and seasonal variation of migraine attacks in children.

    abstract:OBJECT:To investigate the rhythmicity of migraine episodes without aura in a pediatric population. METHODS:Time of occurrence of 2517 migraine attacks in 115 children was recorded, by means of a diary, both by hourly and monthly intervals. RESULTS:A significant circadian variation, characterized by a peak in the afte...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/j.1526-4610.2006.00613.x

    authors: Soriani S,Fiumana E,Manfredini R,Boari B,Battistella PA,Canetta E,Pedretti S,Borgna-Pignatti C

    更新日期:2006-11-01 00:00:00

  • Headache in Petrous Apicitis: A Case Report of Chronic Migraine-like Headache Due to Peripheral Pathology.

    abstract:OBJECTIVE:To report a case of petrous apicitis that manifested as chronic migraine without aura and to discuss the pathophysiological mechanisms behind this presentation. BACKGROUND:Petrous apicitis is a rare complication of acute otitis media with varied clinical presentations that stem from the close proximity of th...

    journal_title:Headache

    pub_type: 杂志文章

    doi:10.1111/head.13643

    authors: Mancini AJ,Glassman RD,Chang YM,Burstein R,Ashina S

    更新日期:2019-11-01 00:00:00