Valsalva-induced cluster: a new subtype of cluster headache.


:We report the case of a man who suffered from Valsalva-induced cluster headaches. The headaches deviated from classic cluster in that they were solely induced by activity involving the Valsalva maneuver, such as coughing and sneezing, and never occurred spontaneously. The attacks were prevented by treatment with indomethacin. This may be the first reported case of cluster that only occurs after a defined trigger and never spontaneously. It also may be the first cluster headache subtype that is indomethacin responsive.






Ko J,Rozen TD





Has Abstract


2002-04-01 00:00:00
















  • Insomnia and perceptual disturbances during flunarizine treatment.

    abstract::We report two cases of sleep disturbances and perceptual disorder appearing in close temporal relationship with initiation of flunarizine therapy for migraine prophylaxis: these side effects disappeared after therapy interruption; resumption of the drug in one case was associated with symptom recurrence. ...


    pub_type: 杂志文章


    authors: Dalla Volta G,Magoni M,Cappa S,Di Monda V

    更新日期:1990-01-01 00:00:00

  • Characteristics of menstrual vs nonmenstrual migraine: a post hoc, within-woman analysis of the usual-care phase of a nonrandomized menstrual migraine clinical trial.

    abstract:OBJECTIVE:To compare, using a within-woman analysis, the severity, duration, and relapse of menstrual vs nonmenstrual episodes of migraine during treatment with usual migraine therapy. BACKGROUND:Studies comparing the clinical characteristics of menstrual and nonmenstrual migraine attacks have yielded conflicting resu...


    pub_type: 临床试验,杂志文章,多中心研究


    authors: MacGregor EA,Victor TW,Hu X,Xiang Q,Puenpatom RA,Chen W,Campbell JC

    更新日期:2010-04-01 00:00:00

  • Management of Pediatric Migraine Headache in the Emergency Room and Infusion Center.

    abstract::Migraine is a common disorder that starts at an early age and takes a variable pattern from intermittent to chronic headache with several exacerbations throughout a lifetime. Children and adolescents are significantly affected. If an acute headache is not aborted by outpatient migraine therapy, it often causes severe ...


    pub_type: 杂志文章,评审


    authors: Kabbouche M

    更新日期:2015-11-01 00:00:00

  • Distinct pharmacokinetic profile and safety of a fixed-dose tablet of sumatriptan and naproxen sodium for the acute treatment of migraine.

    abstract:OBJECTIVE:To describe the pharmacokinetic and safety profiles of sumatriptan 85 mg formulated with RT Technology (RT) and naproxen sodium 500 mg in a fixed-dose combination tablet (sumatriptan/naproxen sodium) that targets both serotonergic dysmodulation and inflammation in migraine. METHODS:Six open-label, crossover ...


    pub_type: 临床试验,杂志文章


    authors: Haberer LJ,Walls CM,Lener SE,Taylor DR,McDonald SA

    更新日期:2010-03-01 00:00:00

  • Subcutaneous sumatriptan in cluster headache: a time study of the effect on pain and autonomic symptoms.

    abstract::A subcutaneous injection of 6 mg sumatriptan rapidly and effectively stopped attacks of cluster headache. After a time lag of 4-14 minutes (mean 7 minutes) pain dramatically dropped to zero within seconds to single minutes (mean 56 seconds). This rapid effect may indicate that mere vasoconstriction is the mechanism be...


    pub_type: 杂志文章


    authors: Hardebo JE

    更新日期:1993-01-01 00:00:00

  • Diagnosis and clinical features of trigemino-autonomic headaches.

    abstract::Although severe short-lasting headaches are rare, they can be considered disabling conditions with a major impact on the quality of life of patients. These headaches can divided broadly in to those associated with autonomic symptoms, so called trigeminal autonomic cephalgias (TACs), and those with few or no autonomic ...


    pub_type: 杂志文章,评审


    authors: May A

    更新日期:2013-10-01 00:00:00

  • Unilateral black hairy tongue in trigeminal neuralgia.

    abstract::Unilateral hairlike discoloration of the tongue is described in a patient with ipsilateral mandibular division trigeminal neuralgia. This unusual physical sign coincided with the patient's painful trigger zone and was attributed to hypertrophy of keratinized filiform papillae, where guarded avoidance of mechanical sti...


    pub_type: 杂志文章


    authors: Cheshire WP Jr

    更新日期:2004-10-01 00:00:00

  • Neuromodulation and Devices in Trigeminal Neuralgia.

    abstract:PREMISE:Trigeminal neuralgia is a severe facial pain disorder that has been studied for decades. Classical trigeminal neuralgia (CTN) is either idiopathic or caused by neurovascular compression. The related painful trigeminal neuropathies are often secondary to other causes, such as multiple sclerosis or trauma. PROBL...


    pub_type: 杂志文章,评审


    authors: Weber K

    更新日期:2017-11-01 00:00:00

  • Headache in patients with baroreflex failure.

    abstract::Two cases of baroreflex failure presented with tension-type/exertional headache. The usefulness of noninvasive physiological tests in diagnosing baroreflex failure and the role of baroreceptors in trigeminal nociception are discussed. ...


    pub_type: 杂志文章


    authors: Khurana RK

    更新日期:2006-07-01 00:00:00

  • Flunarizine versus metoprolol in migraine prophylaxis: a double-blind, randomized parallel group study of efficacy and tolerability.

    abstract::The prophylactic effect of flunarizine and metoprolol was studied in a multi-center randomized, double-blind trial of 149 patients with migraine with or without aura. After a 4-week placebo run-in period, patients were randomly allocated to treatment with flunarizine 10 mg daily or metoprolol 200 mg daily for 16 weeks...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Sørensen PS,Larsen BH,Rasmussen MJ,Kinge E,Iversen H,Alslev T,Nøhr P,Pedersen KK,Schrøder P,Lademann A

    更新日期:1991-11-01 00:00:00

  • Body mass index and adult weight gain among reproductive age women with migraine.

    abstract:OBJECTIVE:To evaluate the cross-sectional relationship between migraine and pregravid obesity; and to assess the risk of adult weight gain among women with history of a pediatric diagnosis of migraine. BACKGROUND:Obesity, comorbid with pain disorders including migraine, shares common pathophysiological characteristics...


    pub_type: 杂志文章,多中心研究


    authors: Vo M,Ainalem A,Qiu C,Peterlin BL,Aurora SK,Williams MA

    更新日期:2011-04-01 00:00:00

  • Olanzapine in the treatment of refractory migraine and chronic daily headache.

    abstract:BACKGROUND:Olanzapine, a thienobenzodiazepine, is a new "atypical" antipsychotic drug. Olanzapine's pharmacologic properties suggest it would be effective for headaches, and its propensity for inducing acute extrapyramidal reactions or tardive dyskinesia is relatively low. We thus decided to assess the value of olanzap...


    pub_type: 杂志文章


    authors: Silberstein SD,Peres MF,Hopkins MM,Shechter AL,Young WB,Rozen TD

    更新日期:2002-06-01 00:00:00

  • Headaches and academic performance in university students: a cross-sectional study.

    abstract:OBJECTIVES:To estimate the 1-year prevalence of headache, its repercussion and its association with the academic performance of university students. METHODS:Cross-sectional study. Three hundred eighty students were randomly selected out of the 1718, 90.5% of them were interviewed. A semi-structured interview, the Head...


    pub_type: 杂志文章


    authors: Souza-e-Silva HR,Rocha-Filho PA

    更新日期:2011-11-01 00:00:00

  • New Onset Focal Stabbing Headache Associated With Peripheral Vertigo: A Case Report.

    abstract::We present a novel case of a focal stabbing headache sharing features of primary stabbing headache that started and resolved with the onset and resolution of a course of self-limiting peripheral vertigo. The association of onset and improvement of the stabbing headaches support the trigeminal and vestibular reciprocal...


    pub_type: 信件


    authors: Chan TLH,Kim DD,Becker WJ

    更新日期:2018-01-01 00:00:00

  • Traumatic intracerebral venous thrombosis associated with an abnormal golf swing.

    abstract:OBJECTIVES:To describe the occurrence of cerebral venous thrombosis in a 40-year-old man whose cerebral event was induced by a poor golf swing, to review the literature on possible mechanisms producing venous thrombosis, and to compare this case with the literature. BACKGROUND:Headache is the most frequent symptom in ...


    pub_type: 杂志文章,评审


    authors: Saneto RP,Samples S,Kinkel RP

    更新日期:2000-07-01 00:00:00

  • Neuronal nitric oxide synthase is involved in the induction of nerve growth factor-induced neck muscle nociception.

    abstract:BACKGROUND:Neck muscle nociception mediated by nitric oxide may play a role in the pathophysiology of tension-type headache. OBJECTIVE:The present study addresses the involvement of neuronal nitric oxide synthase (nNOS) in the facilitation of neck muscle nociception after local application of nerve growth factor (NGF)...


    pub_type: 杂志文章


    authors: Isaak A,Ellrich J

    更新日期:2011-05-01 00:00:00

  • Safety and Tolerability of Fremanezumab for the Prevention of Migraine: A Pooled Analysis of Phases 2b and 3 Clinical Trials.

    abstract:OBJECTIVE:Presentation of pooled analysis of safety data for fremanezumab in patients with chronic (CM) or episodic migraine (EM) from 4 placebo-controlled phase 2b and phase 3 studies. BACKGROUND:There is a need for an effective, safe, and well-tolerated preventive therapy that specifically targets the pathophysiolog...


    pub_type: 杂志文章,meta分析


    authors: Silberstein SD,McAllister P,Ning X,Faulhaber N,Lang N,Yeung P,Schiemann J,Aycardi E,Cohen JM,Janka L,Yang R

    更新日期:2019-06-01 00:00:00

  • A Hospital Based Retrospective Study of Acute Postpartum Headache.

    abstract:OBJECTIVE:To describe acute headache diagnoses in women presenting emergently in the postpartum period and to determine which factors may be associated with secondary vs primary headache. BACKGROUND:Hormonal, vascular, and procedural factors elevate the risk for both secondary and primary headache disorders in the pos...


    pub_type: 杂志文章


    authors: Vgontzas A,Robbins MS

    更新日期:2018-06-01 00:00:00

  • MRA captures vasospasm in fatal migrainous infarction.

    abstract::A 57-year-old woman presented with an escalation of her headaches which ultimately progressed to multiple strokes and death. MRI/MRA demonstrated diffuse vasospasm and other causes of stroke were excluded on premortem investigation and postmortem examination. Reversible MRI abnormalities, vasospasm on angiogram and fa...


    pub_type: 信件


    authors: Marshall N,Maclaurin WA,Koulouris G

    更新日期:2007-02-01 00:00:00

  • Non-compliance with follow-up and improvement after treatment at a headache center.

    abstract::Two telephone surveys were conducted at a major headache center into patient compliance with follow-up and perceived treatment efficacy. The first survey addressed compliance with the recommendation to follow-up after the initial evaluation. Of a group of 316 consecutive patients, 40.5% had not complied with the recom...


    pub_type: 杂志文章


    authors: Spierings EL,Miree LF

    更新日期:1993-04-01 00:00:00

  • Ketamine-Magnesium for Refractory Chronic Cluster Headache: A Case Series.

    abstract:OBJECTIVES:To evaluate the safety and efficacy of ketamine-magnesium combination to reduce attacks in a series of patients with refractory chronic cluster headache (rCCH). BACKGROUND:Refractory chronic cluster headache (CCH) is a rare but highly debilitating condition that needs new treatment options. A previous publi...


    pub_type: 杂志文章


    authors: Moisset X,Giraud P,Meunier E,Condé S,Périé M,Picard P,Pereira B,Ciampi de Andrade D,Clavelou P,Dallel R

    更新日期:2020-11-01 00:00:00

  • Reduced adverse event profile of orally inhaled DHE (MAP0004) vs IV DHE: potential mechanism.

    abstract:BACKGROUND:MAP0004 is a novel orally inhaled formulation of dihydroergotamine mesylate (DHE) currently in development that has been clinically observed to provide rapid ( approximately 10 minutes) therapeutic levels of DHE but with lower rates of adverse effects (dizziness, nausea, and paresthesia) compared with intrav...


    pub_type: 杂志文章


    authors: Cook RO,Shrewsbury SB,Ramadan NM

    更新日期:2009-11-01 00:00:00

  • Impact of the International Headache Society criteria on the use of neuroimaging for headache diagnosis in a headache clinic.

    abstract:OBJECTIVE:To evaluate the impact of the introduction of the International Headache Society (IHS) criteria on the use of neuroimaging for headache diagnosis in a specialist outpatient center. BACKGROUND:The general indications for neuroimaging in headache are a matter of debate. International Headache Society criteria ...


    pub_type: 杂志文章


    authors: Fabbrini G,Barbanti P,Pascali MP,Lenzi GL,Cerbo R

    更新日期:1999-11-01 00:00:00

  • 100% Response Rate to Galcanezumab in Patients With Episodic Migraine: A Post Hoc Analysis of the Results From Phase 3, Randomized, Double-Blind, Placebo-Controlled EVOLVE-1 and EVOLVE-2 Studies.

    abstract:OBJECTIVE:To characterize adult patients with episodic migraine who achieved 100% response to galcanezumab treatment. BACKGROUND:Galcanezumab is a humanized monoclonal antibody that selectively binds to the calcitonin gene-related peptide (CGRP) and has demonstrated efficacy in reducing migraine headache days (MHD) in...


    pub_type: 杂志文章,随机对照试验


    authors: Rosen N,Pearlman E,Ruff D,Day K,Jim Nagy A

    更新日期:2018-10-01 00:00:00

  • Mouth-dispersible aspirin in the treatment of migraine: a placebo-controlled study.

    abstract:OBJECTIVE:To compare the efficacy of mouth-dispersible aspirin 900 mg and placebo in the treatment of migraine. BACKGROUND:Aspirin is widely accepted as an effective therapy for migraine. Previous studies have indicated that gastric stasis and delayed gastric emptying, which occur during migraine attacks, delay aspiri...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: MacGregor EA,Dowson A,Davies PT

    更新日期:2002-04-01 00:00:00

  • Specificity of IHS criteria in childhood headache.

    abstract::We prospectively assessed the relative specificity of the International Headache Society (IHS) criteria in 30 children referred to a pediatric neurologist. An important cause of headache, including raised intracranial pressure with slit ventricle syndrome, would have been missed in 4 children if one had relied on IHS ...


    pub_type: 杂志文章


    authors: Seshia SS

    更新日期:1996-05-01 00:00:00

  • Neurotology of migraine.

    abstract::Neurotologic symptoms are common with migraine, yet relatively little is known about the pathophysiology of such symptoms. Motion sensitivity with bouts of motion sickness occurs in about two thirds of patients with migraine. Episodes of vertigo occur in about one fourth of patients and, in some, vertigo is the only s...


    pub_type: 杂志文章,评审


    authors: Baloh RW

    更新日期:1997-11-01 00:00:00

  • Character of headache in Kimmerle anomaly.

    abstract::The Kimmerle anomaly may be associated with a variety of neurological symptoms. We sought to determine the prevalence and character of these symptoms in a large cohort of afflicted patients. ...


    pub_type: 杂志文章


    authors: Split W,Sawrasewicz-Rybak M

    更新日期:2002-10-01 00:00:00

  • Respiratory sinus arrhythmia in cluster headache syndrome.

    abstract::Respiratory sinus arrhythmia is regarded as indicative of cardiac vagal integrity. A ratio of the longest R-R interval to the shortest R-R interval during deep breathing test (E:I ratio) was calculated in controls (n = 49), cluster headache (n = 33) and CPH (n = 4) patients. E:I ratio decreased with age but was not de...


    pub_type: 杂志文章


    authors: Kruszewski P

    更新日期:1993-02-01 00:00:00

  • Hypnic headache.

    abstract:BACKGROUND:Hypnic headache (HH) is a rare primary headache characterized by strictly sleep-related headache attacks. METHODS:This paper reviews the pertinent literature on HH. RESULTS:Disease information is mainly based on case reports and small case series (around 250 cases) published since its first description in ...


    pub_type: 杂志文章,评审


    authors: Lanteri-Minet M

    更新日期:2014-10-01 00:00:00