Abstract：
BACKGROUND:The number of lymph nodes retrieved and examined from a resected colon cancer specimen may be crucial for correct staging. We examined if efforts to increase the lymph node harvest to more than 12 lymph nodes per specimen would upstage some patients from TNM stage II to III. METHODS:Three hospitals compared results from 2000 with those of 2007 in 421 resected patients with stage II and III colon cancer. Hospital A endeavored to improve the surgical procedure while the pathologists enhanced the quality of lymph node sampling. Hospital B did not make any marked changes, while hospital C introduced the GEWF lymph node solvent (glacial acetic acid, ethanol, distilled water, and formaldehyde) in their pathology method. RESULTS:In 2000, 12 or more lymph nodes were harvested in 39.6, 45.0, and 21.1% of the specimens from the three hospitals, while the figures for 2007 were 85.7, 42.0, and 90.3%, respectively. The significant increase in lymph node harvest in two of the hospitals in 2007 compared to 2000 (p < 0.001) did not affect the share of patients with stage III in 2007 (38.7%) compared to 2000 (44.1%) (p = 0.260). The number of positive lymph nodes and the lymph node ratio (LNR) decreased from 2000 to 2007. A lymph node yield of 12 or more was not associated with an increased probability of positive lymph nodes in a multivariable logistic regression analysis. CONCLUSION:More radical surgery and dedicated pathologists and the use of the GEWF solvent significantly increased the lymph node yield but did not upstage patients from TNM stage II to III.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Storli K,Søndenaa K,Furnes B,Leh S,Nesvik I,Bru T,Gudlaugsson E,Bukholm I,Norheim-Andersen S,Eide Gdoi
10.1007/s00268-011-1248-7subject
Has Abstractpub_date
2011-12-01 00:00:00pages
2796-803issue
12eissn
0364-2313issn
1432-2323journal_volume
35pub_type
临床试验,杂志文章,多中心研究abstract：INTRODUCTION:Preventing secondary insult to the brain is imperative following traumatic brain injury (TBI). Although TBI does not preclude nonoperative management (NOM) of splenic injuries, development of hypotension in this setting may be detrimental and could therefore lead trauma surgeons to a lower threshold for op...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4494-0
更新日期：2018-08-01 00:00:00
abstract：BACKGROUND:Laparoscopic intersphincteric resection (ISR) after neoadjuvant chemoradiation is helpful in the management of patients with low rectal cancer. With the advent of this technique, the need for performance of abdominoperineal resection seems to have decreased in patients with very low rectal tumors. The aim of...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1277-2
更新日期：2011-12-01 00:00:00
abstract：:There is a need for relevant, valid, and practical metrics to better quantify both need and progress in global pediatric surgery and for monitoring systems performance. There are several existing surgical metrics in use, including disability-adjusted life years (DALYs), surgical backlog, effective coverage, cost-effec...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-018-4868-3
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Recently, diagnostic criteria for malnutrition have been proposed by the European Society for Clinical Nutrition and Metabolism (ESPEN). This study aimed to investigate the utility of the ESPEN malnutrition criteria as a predictor for major complications following hepatectomy and pancreatectomy. METHODS:Dat...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05767-w
更新日期：2021-01-01 00:00:00
abstract：:In a retrospective study the clinical course of 40 patients with symptomatic persistent or recurrent parathyroid cancer was analyzed in order to assess the value of aggressive surgical intervention. Recurrence was diagnosed after a median period of 33 months (1-228 months). Twenty-two patients had locoregional disease...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF00353773
更新日期：1994-07-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
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abstract：BACKGROUND:Neuroendocrine neoplasias (NEN) of the gastroenteropancreatic (GEP) system frequently present with metastatic deposits. The proliferation marker Ki-67 is used for diagnosis and to assess the prognosis of disease. The aim of our study was to evaluate the usefulness of Ki-67 % in the assessment of NEN patients...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2451-0
更新日期：2014-06-01 00:00:00
abstract：:A new technique for ligating vessels and similar structures that offers more security is described. The aim of the study was to test whether this hypothesis was correct. Six different types of knots, including the one described in this article were compared by a strength-testing study. The knots were tied on a silicon...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
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journal_title：World journal of surgery
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doi：10.1007/s00268-001-0237-7
更新日期：2002-03-01 00:00:00
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journal_title：World journal of surgery
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journal_title：World journal of surgery
pub_type： 杂志文章,评审
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journal_title：World journal of surgery
pub_type： 临床试验,杂志文章
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更新日期：2010-11-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF00308623
更新日期：1995-03-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
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更新日期：2014-12-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
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更新日期：1996-05-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章,评审
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更新日期：2006-11-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF02067331
更新日期：1992-07-01 00:00:00
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更新日期：2015-07-01 00:00:00
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更新日期：2010-07-01 00:00:00
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journal_title：World journal of surgery
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journal_title：World journal of surgery
pub_type： 杂志文章
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更新日期：1996-09-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
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更新日期：2012-08-01 00:00:00
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journal_title：World journal of surgery
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更新日期：2007-04-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00268-015-3260-9
更新日期：2016-01-01 00:00:00
abstract：:This study described the various components of access to care for resectable colorectal cancer, and correlated the timeliness of these components with patient satisfaction. With a prospective/retrospective cohort design, all patients undergoing surgical resection for primary colorectal cancer from 2/1/01 to 15/12/01, ...
journal_title：World journal of surgery
pub_type： 杂志文章
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更新日期：2005-11-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
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更新日期：2019-01-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
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更新日期：2014-11-01 00:00:00
abstract：BACKGROUND:Surgery is increasingly recognized as a means to reduce the morbidity and mortality of disabling impairments in resource-limited environments. We sought to estimate the burden of surgically correctable disabling impairments and the cost-effectiveness of their treatment among children in a large refugee camp....
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1899-z
更新日期：2013-07-01 00:00:00
abstract：:Surgical education in the United Kingdom has evolved to meet the need of the National Health Service (NHS) for a relatively small body of consultants practicing autonomously and carrying ultimate clinical responsibility for their patients. This form of specialist practice is markedly different from that found in most ...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF00298916
更新日期：1994-09-01 00:00:00
