Abstract：
BACKGROUND:The aim of this study was to compare the results of percutaneous radiofrequency ablation (RFA) with those of partial hepatectomy (PH) in the treatment of multicentric small hepatocellular carcinomas (HCCs). With advances in RFA, it is not known whether the minimally invasive approach with percutaneous RFA could attain comparable survival outcomes but with a lower morbidity in patients with multicentric HCCs. METHODS:From January 2002 and December 2007, 159 patients who had two or three HCCs, with the largest tumor no more than 5 cm in diameter, had no major vascular invasion or extrahepatic metastases, and were treated with either PH (n = 73) or RFA (n = 86) were included in the study. RESULTS:There was no procedure-related mortality in both groups of patients. Major complications happened significantly more often after PH than after RFA (19.2 vs. 8.1%). The hospital stay was significantly longer after PH than after RFA (median = 9 vs. 3 days). The 1-, 3-, and 5-year overall survival rates for the PH and RFA groups were 91.8, 68.7, 44.5% and 94.2, 64.4, 21.2%, respectively. The corresponding disease-free survival rates for the two groups were 62.1, 33.6, 3.6% and 29.4, 2.7, 0%, respectively. The PH group had significantly longer overall survival and disease-free survival than the RFA group. CONCLUSIONS:PH resulted in better survival outcomes than RFA for patients with multicentric small HCCs. However, RFA had the benefits of lower procedure-related morbidity and shorter hospital stay.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Guo WX,Zhai B,Lai EC,Li N,Shi J,Lau WY,Wu MC,Cheng SQdoi
10.1007/s00268-010-0732-9subject
Has Abstractpub_date
2010-11-01 00:00:00pages
2671-6issue
11eissn
0364-2313issn
1432-2323journal_volume
34pub_type
临床试验,杂志文章abstract：:The moral dilemmas faced by surgeons worldwide who treat patients infected with the human immunodeficiency virus (HIV) can be viewed against the background of experience in sub-Saharan countries, where the community prevalence is in excess of 25% (90% of hospital inpatients). When seeking consent for an HIV test befor...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-7101-x
更新日期：2003-08-01 00:00:00
abstract：:The aim of the present study was to determine whether patients with the incident hospital diagnosis of primary hyperparathyroidism (PHPT) in Denmark during the period 1977-1993 had an increased mortality from cardiovascular disease and cancer compared to the rest of the Danish population. In a random sample of half of...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-7046-0
更新日期：2004-01-01 00:00:00
abstract：BACKGROUND:Over the past decade, assessments of surgical capacity in low- and middle-income countries (LMICs) have contributed to our understanding of barriers to the delivery of surgical services in a number of countries. It is yet unclear, however, how the findings of these assessments have been applied and built upo...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-014-2938-8
更新日期：2015-04-01 00:00:00
abstract：INTRODUCTION:Jejunal diverticula are rare lesions, and when complications arise, they pose diagnostic difficulties. Perforation is a common complication resulting in an acute abdomen, although preoperative diagnosis is usually not possible. The "gold standard" for management for patients with complications is surgery. ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9469-0
更新日期：2008-07-01 00:00:00
abstract：BACKGROUND:This study reviews the 15 year program of our Department of Pediatric Surgery for the treatment and follow-up of children born with a cleft in Benin and Togo. METHODS:We analyzed files of children born in Africa with a cleft. They were referred to us through a nongovernmental organization (NGO) between 1993...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1607-z
更新日期：2012-08-01 00:00:00
abstract：:We analyzed clinical features and genetic alterations in the noncancerous and cancerous biliary lesions obtained from pancreaticobiliary maljunction (PBM) patients. Gallbladder (GB) and bile duct (BD) lesions were obtained surgically from 36 patients with PBM, and polymerase chain reaction (PCR) methods were used to e...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0187-0
更新日期：2002-01-01 00:00:00
abstract：BACKGROUND:The splintering of general surgery into subspecialties in the past decade has brought into question the relevance of a continued emphasis on traditional general surgical training. With the majority of trainees now expressing a preference to subspecialise early, this study sought to identify if the requiremen...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2890-7
更新日期：2015-02-01 00:00:00
abstract：BACKGROUND:The adoption of robotic systems for gastric cancer surgery has been proven feasible and safe; however, a benefit over the laparoscopic approach has not yet been well-documented. We aimed to investigate the surgical outcomes of robotic versus laparoscopic gastrectomy for gastric cancer, according to the exten...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-2998-4
更新日期：2015-07-01 00:00:00
abstract：:We reviewed our experience with 34 patients with metastatic endocrine tumors (METs) who were treated by different modalities. Eight patients were treated by chemotherapy or chemoembolization because of stable disease or surgical contraindications. Seventeen patients underwent curative or cytoreductive surgical resecti...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900138
更新日期：1996-09-01 00:00:00
abstract：:This retrospective study in 79 surgically treated patients with a proximal bile duct carcinoma revealed 12 patients with a median age of 59.5 years (range 21-73 years) who survived more than 5 years. These 12 patients were analyzed to identify specific patient characteristics for long-term survival. Fifteen patients d...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900571
更新日期：1999-01-01 00:00:00
abstract：:The appropriate role for additional radiotherapy in patients with resectable rectal cancer is not yet settled. Irradiation has been considered by surgeons and radiotherapists as superfluous since no effect on survival has been shown. However, numerous trials have demonstrated that peri-operative radiotherapy decreases...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF02066982
更新日期：1992-09-01 00:00:00
abstract：BACKGROUND:The prognosis of intrahepatic cholangiocarcinoma (ICC) remains poor despite improvements in treatment and post-operative clinical management. We review our experiences and evaluate our current surgical approaches by comparing patients from two consecutive treatment periods. METHODS:One hundred forty-four pa...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3583-1
更新日期：2016-09-01 00:00:00
abstract：BACKGROUND:The stapled hemorrhoidopexy is reported to have a low recurrence while treating the major hemorrhoidal symptoms of bleeding and prolapse. The aim of this study is to obtain long-term results on the outcome of the stapled hemorrhoidopexy. METHODS:All patients with a hemorrhoidal disease grade III, who underw...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05065-0
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:Surgical treatment of amiodarone-associated thyrotoxicosis (AAT) is effective although fewer than 100 cases have been reported world wide. MATERIALS AND METHODS:We reviewed 14 patients treated with total thyroidectomy by a single surgeon from 1998 to 2005. RESULTS:There were 11 male and 3 female patients w...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-005-0673-x
更新日期：2006-11-01 00:00:00
abstract：:A mathematic model is created to determine the economic cost per year of anticipated prolongation of life that would result from a program of abdominal ultrasonographic (US) screening for abdominal aortic aneurysm. The protocol involves US screening at age 60, 67, and 74 years with additional annual follow-up US and e...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01659032
更新日期：1989-05-01 00:00:00
abstract：BACKGROUND:Since the human genome has been sequenced many mysteries of cell biology have been unravelled, thereby clarifying the pathogenesis of several diseases, particularly cancer. In members of kindreds with certain hereditary diseases, it is now possible early in life to predict with great certainty whether or not...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-006-0616-1
更新日期：2007-03-01 00:00:00
abstract：BACKGROUND:The survival outcome in lung cancer patients with chronic kidney disease (CKD) has not been well evaluated. The aim of this study was to evaluate the survival outcomes following non-small cell lung cancer (NSCLC) surgery in patients with CKD as a preoperative comorbidity. METHODS:Among 671 patients who unde...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05143-3
更新日期：2019-12-01 00:00:00
abstract：:The value of surgical resection for patients with chronic pancreatitis has been debated on account of persistent symptoms and the morbidity of the operative procedure, both immediate and delayed. This paper explores the consequence of pancreatoduodenectomy in 175 patients with chronic pancreatitis who were operated on...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-7239-6
更新日期：2003-11-01 00:00:00
abstract：BACKGROUND:The goal of this study was to evaluate the outcome of patients who had the Nuss procedure for repair of pectus excavatum. METHODS:Thirty-nine patients (26 male, 13 female) of 61 (63.9%) who had bar removal after the Nuss procedure agreed to participate in an interview. All patients and their parents were as...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1111-x
更新日期：2011-07-01 00:00:00
abstract：:We evaluated the morbidity associated with primary closure by interrupted subcuticular absorbable sutures following emergency appendectomy. In a prospective clinical trial over a 12-month period, 216 children who underwent emergency appendectomy had skin closure using subcuticular interrupted absorbable polyglactin 4-...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章
doi：10.1007/s002689900007
更新日期：1996-01-01 00:00:00
abstract：:A minority of patients with papillary thyroid carcinoma (PTC) is at high-risk of developing recurrent disease and death. Risk group stratification as defined by age, metastases to distant site, extrathyroidal invasion, and tumor size (AMES) criteria is frequently employed to identify high-risk patients for aggressive ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7420-6
更新日期：2004-11-01 00:00:00
abstract：:The goal of fluid resuscitation in the burn patient is maintenance of vital organ function at the least immediate or delayed physiological cost. To optimize fluid resuscitation in severely burned patients, the amount of fluid should be just enough to maintain vital organ function without producing iatrogenic pathologi...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF02067109
更新日期：1992-01-01 00:00:00
abstract：:Innovation is responsible for most advances in the field of surgery. Innovative approaches to solving clinical problems have significantly decreased morbidity and mortality for many surgical procedures, and have led to improved patient outcomes. While innovation is motivated by the surgeon's expectation that the new a...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2568-1
更新日期：2014-07-01 00:00:00
abstract：:A family history of colorectal cancer is a known risk factor for the disease. As a result of different study designs from different populations, the strength of this association varies in the literature. We intended to define the incidence and the risk predictors in first-degree relatives of patients with colorectal c...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900217
更新日期：1997-02-01 00:00:00
abstract：:Variceal bleeding remains an important complication in extrahepatic portal vein thrombosis (EPVT). As for portal hypertension due to other etiologies, an elective treatment to decrease the risk of subsequent rebleeding is warranted. The results of the Sugiura-Futagawa procedure (SP) in 38 patients with variceal bleedi...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF00294409
更新日期：1994-03-01 00:00:00
abstract：BACKGROUND:Surgeon performed ultrasound (US) is being increasingly embraced by breast surgeons worldwide as an integral part of patient assessment. The extent of its application within Australia and New Zealand is not well documented. The present study aimed to evaluate its current usage patterns and to determine suita...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-2076-8
更新日期：2013-09-01 00:00:00
abstract：:Hepatobiliary (HB) surgery is a challenging surgical subspecialty that requires highly specialized training and an adequate level of experience in order to be performed safely. As a result, minimally invasive HB surgery has been met with slower acceptance as compared to other subspecialties, with many surgeons in the ...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-013-2276-2
更新日期：2013-12-01 00:00:00
abstract：:Fourteen patients with liver tumor malignancy and sixteen patients with malignant melanoma localized to one limb were studied regarding leukocyte activation with the release of polymorphonuclear neutrophilic (PMN) elastase and of neopterin and formation of cytokines (TNF-alpha and IL-6) during the surgical treatment. ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF00299787
更新日期：1995-11-01 00:00:00
abstract：BACKGROUND:Utilization of breast reconstruction (BR) is low in many jurisdictions. We studied the geographical and surgical workforce factors that contribute to access and use of BR using a small area analysis approach with a geographical unit of analysis. METHODS:We linked administrative data from Ontario Canada to c...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3060-2
更新日期：2015-08-01 00:00:00
abstract：:There is a need for relevant, valid, and practical metrics to better quantify both need and progress in global pediatric surgery and for monitoring systems performance. There are several existing surgical metrics in use, including disability-adjusted life years (DALYs), surgical backlog, effective coverage, cost-effec...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-018-4868-3
更新日期：2019-06-01 00:00:00
