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Comparisons of inhibin B versus antimüllerian hormone in poor ovarian responders undergoing in vitro fertilization.

Abstract：

OBJECTIVE:To evaluate serum inhibin B as a predictor of poor ovarian response in patients undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF-ICSI) and to compare it with the performance of antimüllerian hormone (AMH). DESIGN:Meta-analysis. SETTING:University hospital. PATIENT(S):Patients undergoing IVF. INTERVENTION(S):None. MAIN OUTCOME MEASURE(S):Poor ovarian response in controlled ovarian hyperstimulation (COH). RESULT(S):Fifteen studies on serum inhibin B and 12 studies on AMH were selected for meta-analysis. Both basal and stimulated inhibin B levels were statistically significantly lower in poor ovarian responders than in controls. The estimated summary receiver operating characteristic (ROC) curves suggested that stimulated inhibin B was more accurate than basal inhibin B and AMH in the prediction of poor ovarian response. CONCLUSION(S):Both basal and stimulated serum inhibin B levels are lower in poor responders than in controls. Compared with AMH, stimulated inhibin B is a more accurate predictor of ovarian response in patients undergoing IVF, making it a potentially useful tool in future IVF practice.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Tan R,Pu D,Liu L,Liu J,Wu J

doi

10.1016/j.fertnstert.2011.07.1102

subject

Has Abstract

pub_date

2011-10-01 00:00:00

pages

905-11

issue

4

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(11)02218-7

journal_volume

96

pub_type

杂志文章,meta分析

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