Recognition of differentiation antigens of spermatogenesis in the mouse by using antibodies from spleen cell-myeloma hybrids after syngeneic immunization.

Abstract:

:Two differentiation antigens of spermatogenesis in the mouse are defined by monoclonal antibodies from hybridomas produced between the myeloma P3-X63Ag8 and spleen lymphocytes immunized with syngeneic testis cells. These antigens are on testis cells, and not liver, kidney, brain, spleen, or whole ovary. They are species but not strain specific and trypsin sensitive but collagenase insensitive. On the basis of their appearance during the onset of spermatogenesis they appear to be differentiation antigens expressed during different but overlapping time windows during spermatogenesis.

authors

Bechtol KB,Brown SC,Kennett RH

doi

10.1073/pnas.76.1.363

subject

Has Abstract

pub_date

1979-01-01 00:00:00

pages

363-7

issue

1

eissn

0027-8424

issn

1091-6490

journal_volume

76

pub_type

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