Abstract:
:Neuroimaging has become part of the required investigations when assessing a patient with dementia. In this brief paper, we summarize the role of computed tomography (CT) in the routine work-up in dementia and provide some information about the role of the CT scan in the field of dementia research. Although CT is far less sensitive than magnetic resonance imaging (MRI) in detecting changes associated with cognitive impairment, it may still have a role in this regard. This role is mainly that of detecting secondary, sometimes treatable causes of cognitive impairment, such as intracranial masses. In this sense, CT should be seen as a first-line tool. Possible advantages of CT are lower cost; shorter acquisition time, making it more adaptable to patients with poor compliance; and the possibility that it can be performed in patients with metal devices, such as a pacemaker. The role of CT in the field of dementia research is very restricted in comparison to that of MRI, and is limited to the structural assessment of vascular lesions, and to a lesser extent, to that of degenerative changes, particularly when using specific slicing.
journal_name
Int Psychogeriatrjournal_title
International psychogeriatricsauthors
Pasi M,Poggesi A,Pantoni Ldoi
10.1017/S1041610211000950subject
Has Abstractpub_date
2011-09-01 00:00:00pages
S6-12eissn
1041-6102issn
1741-203Xpii
S1041610211000950journal_volume
23 Suppl 2pub_type
杂志文章,评审abstract::The reliability and validity of the Subjective Burden Scale (SBS) were investigated in 255 Japanese family caregivers of elderly relatives with dementia. Values of the Cronbach's alpha reliability, split-half reliability (r), and test-retest reliability (r) were .87, .80, and .72, respectively. The SBS score was signi...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610299005712
更新日期:1999-06-01 00:00:00
abstract:BACKGROUND:Emotional distress associated with Parkinson's disease (PD) increases disease burden and decreases functioning. The literature supports the benefits of psychological interventions for amelioration of emotional distress in persons with PD. The objective of this study is to apply the Contextual Adult Lifespan ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610216000569
更新日期:2016-10-01 00:00:00
abstract::Over 20 years ago, the Australian Liberal/National Party Federal Opposition had a set of policies with which it hoped to persuade the Australian people to return it to government in the election due in 1996. This particular collection of proposed initiatives was called "The things that matter". When the then leader of...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610216000387
更新日期:2016-06-01 00:00:00
abstract::Thirty-seven subjects, 15 with a clinical diagnosis of Alzheimer's disease and 22 normal controls, participated in a study of the accuracy of telephone screening in identifying potential dementia cases. The telephone protocol and scoring algorithm resulted in 100% sensitivity and 91% specificity. The findings suggest ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610295002171
更新日期:1995-10-01 00:00:00
abstract:BACKGROUND:Mild cognitive impairment (MCI) is proposed to describe the transitional stage between normal cognitive aging and dementia. It has had significant impact in the field of dementia research, but it remains controversial whether or not it should be used as a diagnostic category in clinical practice. METHODS:Se...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610208007126
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:Older Puerto Ricans belong to two rapidly growing demographic groups known to have high rates of depression: the aging and Hispanic populations. Studies of depression in Puerto Ricans have primarily focused on the impact of demographic factors and health. This study expands previous research, examining the r...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610203009505
更新日期:2003-09-01 00:00:00
abstract::Staging methodologies are an essential tool in the assessment of disease severity in progressive dementing illness. Several different instruments have been developed for this purpose. One of the most widely used methodologies is the Global Deterioration Scale/Functional Assessment Staging (GDS/FAST) system. This syste...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610297004869
更新日期:1997-01-01 00:00:00
abstract::ABSTRACTThe aim of the present study is to investigate the impact of benzodiazepine use on cognitive performance in primary care patients with first cognitive complaints. The association between the exposition to benzodiazepines (short and long half-life) and cognitive performance, evaluated through the Mini Mental St...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161021700223X
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Despite the high consistency of evidence in favor of person-centered care, little information is available on how person-centered and family-centered interventions are actually provided. The aim of this study is to gain insight into the provision of the effective New York University Caregiver Intervention (N...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610210000050
更新日期:2010-08-01 00:00:00
abstract::Dementia is defined as global cognitive impairment that interferes with function; however, function has been less well measured than cognition in anti-dementia drug trials. In the modern era of anti-dementia clinical trials, measurement of function has improved by differentiating between the aspects of function that h...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610207004966
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVES:People with dementia can face barriers when trying to access care after a diagnosis, particularly in young-onset dementia (YOD). Little is known about the effects of ethnicity on the use of anti-dementia medication and variations between age groups. The aim of this study was to analyze national data on varia...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610220000794
更新日期:2020-06-02 00:00:00
abstract::The purpose of this study was to examine the relationship between age-associated changes in central serotonergic function and abnormalities associated with major depression. Under randomized double-blind conditions, prolactin and cortisol responses to the serotonin-releasing agent d,l-fenfluramine hydrochloride (60 mg...
journal_title:International psychogeriatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1017/s1041610296002499
更新日期:1996-04-01 00:00:00
abstract::ABSTRACTBackground and Purpose:The impact of dementia-related stressors and strains have been examined for their potential to threaten the well-being of either the person with dementia or the family care partner, but rarely have studies considered the dyadic nature of well-being in dementia. The purpose of this study ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161021800203X
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:It is unclear how brain reserve interacts with gender and apolipoprotein E4 (APOE4) genotype, and how this influences the progression of Alzheimer's disease (AD). The association between intracranial volume (ICV) and progression to AD in subjects with mild cognitive impairment (MCI), and differences accordin...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161021500229X
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:To review the currently available data on the use of ketamine in the treatment of depression among older adults from randomized controlled studies. DESIGN:Randomized controlled trials. SETTING:Variable. PARTICIPANTS:60 years and older with depression. INTERVENTION:Ketamine. MEASUREMENTS:Change in Montgom...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610220000903
更新日期:2020-06-30 00:00:00
abstract:BACKGROUND:The aim of this study was to examine and test the sensitivity, specificity, and threshold scores of the Montreal Cognitive Assessment (MoCA) and the Mini-Mental State Examination (MMSE) and determine those that best correspond to a clinical diagnosis of dementia with Lewy bodies (DLB). METHODS:Sixty-seven A...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213001245
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Vocally disruptive behavior (VDB) in the elderly is a common condition, especially in people with dementia, but difficult to treat. It may occur in as many as 40% of nursing home residents. This study is a review of the existing literature on this condition. METHOD:The literature review was conducted using ...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/S1041610208006728
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:The clinical presentations in dementia with Lewy bodies (DLB) and frontotemporal dementia (FTD) overlap considerably with that of Alzheimer's disease (AD) despite different pathological processes. Autopsy studies have also shown that multiple brain pathology occurs frequently, even in cases with a single cli...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610209009454
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:There is a paucity of simulation-based dementia education programmes for acute care settings that support the development of interpersonal skills pertinent to good care. Moreover, few studies measure the effectiveness of such programmes by evaluating the persistence of practice change beyond the immediate ti...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218002193
更新日期:2020-12-01 00:00:00
abstract::Dementia is a neurodegenerative disorder with global impact, with the largest proportion of cases occurring in low- and middle-income countries. It is estimated that there are 46.8 million cases globally with approximately 10 million new cases each year or a new case occurring every 3 sec (Prince et al., 2015). For co...
journal_title:International psychogeriatrics
pub_type: 社论
doi:10.1017/S1041610217001685
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:Data on psychotropic medications of older patients with schizophrenia spectrum disorder are scarce. Specifically, information about the use of benzodiazepines among older patients with schizophrenia spectrum disorder is very limited. Because benzodiazepine use in older patients has been associated with many ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610219000358
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Sleep disturbance is common in caregivers of older adults with memory disorders. Little is known, however, about the implications of caregivers' poor sleep with regard to their physical functioning. METHODS:In this cross-sectional study, we investigated the association between objectively measured sleep and...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610209991153
更新日期:2010-03-01 00:00:00
abstract::ABSTRACTBackground:Cognition is multidimensional, and each domain plays a unique and crucial part in successful daily life engagement. However, less attention has been paid to multi-domain cognitive health for the elderly, and the role of lifestyle factors in each domain remains unclear. METHODS:We conducted a cross-...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217003076
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:The orbitofrontal cortex has been implicated as a key component in depression by several imaging studies. This study aims to examine morphometrically glial cell and neuronal density and neuronal volume in the orbitofrontal cortex of late-life major depression patients. METHODS:Post mortem tissue from 13 pat...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610210000700
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:This article analyzes the natural history of wandering behavior throughout the course of dementia. DESIGN:Prospective, 10-year, longitudinal study of wandering behavior in dementia, with autopsy follow-up. SETTING:Participants with dementia, living at home with a carer. All lived in Oxfordshire, UK. PARTIC...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610201007542
更新日期:2001-06-01 00:00:00
abstract:INTRODUCTION:A considerable number of adults with dementia live in residential aged care facilities, where loneliness and boredom are common. Computer-based and electronic technologies have advanced significantly and there is potential for such technologies to improve engagement of residents with dementia. However, the...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610219001388
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Frailty in older adults is a multifactorial syndrome defined by low metabolic reserve, less resistance to stressors, and difficulty in maintaining organic homeostasis due to cumulative decline of multiple physiological systems. The relationship between frailty and cognition remains unclear and studies about ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212000907
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:Family involvement in long-term care (LTC) is important but it can prove challenging and result in conflict with staff if families do not feel connected to the LTC facility or if they believe that their contributions are undervalued. According to McMillan & Chavis (1986), sense of community (SOC) refers to a...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212001524
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:The Charles Bonnet syndrome (CBS) is characterized by distinct visual hallucinations and ocularpathology causing visual impairment in patients with insight and the absence of psychiatric comorbidity. The number of reported cases of CBS is expanding as the population ages and the prevalence of vision disorder...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213000719
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Depressive symptoms are common in patients with Alzheimer's disease (AD) and increase the caregiver burden, although the etiology and pathologic mechanism of depressive symptoms in AD patients remain unclear. In this study, we tried to clarify the cerebral blood flow (CBF) correlates of subjective depressive...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213002573
更新日期:2014-05-01 00:00:00