Plasticity of somatosensory inputs to the cochlear nucleus--implications for tinnitus.

Abstract:

:This chapter reviews evidence for functional connections of the somatosensory and auditory systems at the very lowest levels of the nervous system. Neural inputs from the dosal root and trigeminal ganglia, as well as their brain stem nuclei, cuneate, gracillis and trigeminal, terminate in the cochlear nuclei. Terminations are primarily in the shell regions surrounding the cochlear nuclei but some terminals are found in the magnocellular regions of cochlear nucleus. The effects of stimulating these inputs on multisensory integration are shown as short and long-term, both suppressive and enhancing. Evidence that these projections are glutamatergic and are altered after cochlear damage is provided in the light of probable influences on the modulation and generation of tinnitus.

journal_name

Hear Res

journal_title

Hearing research

authors

Shore SE

doi

10.1016/j.heares.2011.05.001

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

38-46

issue

1-2

eissn

0378-5955

issn

1878-5891

pii

S0378-5955(11)00133-X

journal_volume

281

pub_type

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