Computational models of hair cell bundle mechanics: III. 3-D utricular bundles.

abstract：:Strial marginal cells are known to take up and metabolize glucose as their main source of metabolic energy. The membrane transport mechanisms for glucose uptake into strial marginal cells, however, are largely unknown. Two types of glucose transporters in mammalian cells have been described, the facilitated glucose tr...

journal_title：Hearing research

authors： Takeuchi S,Ando M

更新日期：1997-12-01 00:00:00

abstract：:A number of studies have shown that the ear can be protected from sound over-exposure, either by activating the cochlear efferent system, or by sound 'conditioning' in which the role of the efferent system is less certain. To study more definitively the molecular basis of deliberately induced cochlear protection from ...

journal_title：Hearing research

authors： Vázquez AE,Luebke AE,Martin GK,Lonsbury-Martin BL

更新日期：2001-06-01 00:00:00

abstract：:Distortion-product emissions at 2f1-f2 were measured in developing, pigmented rats to determine the characteristics of the functional onset and maturation of these emitted responses. Distortion-product testing was conducted on postnatal days 12, 14, 18, 21, 24, 28, and 51. The geometric-mean frequencies of the primari...

journal_title：Hearing research

authors： Henley CM 3rd,Owings MH,Stagner BB,Martin GK,Lonsbury-Martin BL

更新日期：1990-01-01 00:00:00

abstract：:Recent studies have shown that the vestibular and auditory systems of some species of birds have the capacity to generate sensory hair cells postnatally. We used a traditional technique, 3H-thymidine autoradiography, and a newer method, bromodeoxyuridine immunocytochemistry, to determine whether ongoing proliferation ...

journal_title：Hearing research

authors： Roberson DF,Weisleder P,Bohrer PS,Rubel EW

更新日期：1992-01-01 00:00:00

abstract：:Electrophysiological recordings in the dorsal cochlear nucleus (DCN) were conducted to determine the nature of changes in single unit activity following intense sound exposure and how they relate to changes in multiunit activity. Single and multiunit spontaneous discharge rates and auditory response properties were re...

journal_title：Hearing research

authors： Finlayson PG,Kaltenbach JA

更新日期：2009-10-01 00:00:00

abstract：:Genetically manipulated mice have gained a prominent role in in vivo research on development and function of the auditory system. A prerequisite for the interpretation of normal and abnormal structural and functional features of the inner ear is the exact knowledge of the cochlear place-frequency map. Using a stereota...

journal_title：Hearing research

authors： Müller M,von Hünerbein K,Hoidis S,Smolders JW

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:Molecular analysis using archival human inner ear specimens is challenging because of the anatomical complexity, long-term fixation, and decalcification. However, this method may provide great benefit for elucidation of otological diseases. Here, we extracted mRNA for RT-PCR from tissues dissected from archiv...

journal_title：Hearing research

authors： Kimura Y,Kubo S,Koda H,Shigemoto K,Sawabe M,Kitamura K

更新日期：2013-08-01 00:00:00

abstract：:58 chicks or chick embryos were continuously exposed during 12 h on either embryonic day 18 or 20 or on post-hatching days 1, 10, 20 or 30 to 1.5 kHz pure tone at an intensity of 125 dB SPL. After a 20- or 30-day survival time, audiograms were recorded and then the basilar papillae were prepared for scanning electron ...

journal_title：Hearing research

authors： Cousillas H,Rebillard G

更新日期：1985-01-01 00:00:00

abstract：:Temporal modulation transfer functions (TMTF) were obtained from four European starlings (Sturnus vulgaris) using a psychophysical Go/NoGo procedure combined with the method of constant stimuli. The TMTF for a continuous, broad-band noise of 55 dB SPL had a low-pass characteristic with a cut-off frequency of 123 Hz. F...

journal_title：Hearing research

authors： Klump GM,Okanoya K

更新日期：1991-03-01 00:00:00

abstract：:Pairs of single units were recorded simultaneously from the same microelectrode in the medial geniculate body (MGB) of nitrous oxide anaesthetized cats. Crosscorrelation histograms of each spike train pairs were computed and distributed in five main classes, interpreted in terms of functional interaction between neigh...

journal_title：Hearing research

authors： Heierli P,de Ribaupierre F,de Ribaupierre Y

更新日期：1987-01-01 00:00:00

abstract：:Carboplatin is currently being used as an anticancer drug against human cancers. However, high dose of carboplatin chemotherapy resulted in hearing loss in cancer patients. We have shown that carboplatin-induced hearing loss was related to dose-dependent oxidative injury to the cochlea in rat model. However, the time ...

journal_title：Hearing research

authors： Husain K,Scott B,Whitworth C,Rybak LP

更新日期：2004-05-01 00:00:00

abstract：:In this study 9 human temporal bones from 8 individuals were fixed with Karnovsky solution by perilymphatic perfusion within 1-3 h after death and examined using the "block-surface method' (Spoendlin and Brun, 1974; Spoendlin and Schrott, 1987) and the "micro-dissection method' (Johnsson and Hawkins, 1967). The audiog...

journal_title：Hearing research

authors： Felder E,Schrott-Fischer A

更新日期：1995-11-01 00:00:00

abstract：:Laser scanning confocal microscopy was used to determine the distribution of actin, spectrin and tubulin in whole mounts of the organ of Corti of guinea pig, monkey, rat and chinchilla. Actin, spectrin and tubulin were localized in all cell types in the auditory epithelium. No specialized cytoskeletal organization of ...

journal_title：Hearing research

authors： Raphael Y,Athey BD,Wang Y,Lee MK,Altschuler RA

更新日期：1994-06-01 00:00:00

abstract：:Certain hair cells of fish exhibit strong immunoreactivity to an S-100 antibody. By their spatial locations in the utricle and saccule, these hair cells appear to possess a relatively short kinocilium and a roughly ovoid cell shape. In the utricle, these cells are predominantly located in the striola. In the saccule, ...

journal_title：Hearing research

authors： Saidel WM,Presson JC,Chang JS

更新日期：1990-08-01 00:00:00

abstract：BACKGROUND:The heterogeneity of tinnitus is substantial. Its numerous pathophysiological mechanisms and clinical manifestations have hampered fundamental and treatment research significantly. A decade ago, the Tinnitus Research Initiative introduced the Tinnitus Sample Case History Questionnaire, a case history instrum...

journal_title：Hearing research

authors： Genitsaridi E,Partyka M,Gallus S,Lopez-Escamez JA,Schecklmann M,Mielczarek M,Trpchevska N,Santacruz JL,Schoisswohl S,Riha C,Lourenco M,Biswas R,Liyanage N,Cederroth CR,Perez-Carpena P,Devos J,Fuller T,Edvall NK,Hellbe

更新日期：2019-06-01 00:00:00

abstract：:Carboplatin preferentially destroys inner hair cells (IHCs) in the chinchilla inner ear, while retaining a near-normal outer hair cell (OHC) population. The present study investigated the functional consequences of IHC loss on the compound action potential (CAP), inferior colliculus potential (ICP) and auditory cortex...

journal_title：Hearing research

authors： Qiu C,Salvi R,Ding D,Burkard R

更新日期：2000-01-01 00:00:00

abstract：:Guinea pigs were exposed to a 10 kHz pure tone and damage to the cochlea was investigated immediately after exposure, or after a recovery period ranging from 18-25 days. Structural damage was assessed using scanning electron microscopy and functional damage estimated using the N1 threshold audiogram. Exposure at 106 d...

journal_title：Hearing research

authors： Robertson D,Johnstone BM,McGill TJ

更新日期：1980-01-01 00:00:00

abstract：:The origins of extrinsic projections to the guinea pig dorsal and ventral cochlear nuclei were identified by examining the retrograde transport of horseradish peroxidase conjugated to wheatgerm agglutinin following its injection into each of these divisions. Major projections originated in periolivary regions of the s...

journal_title：Hearing research

authors： Shore SE,Helfert RH,Bledsoe SC Jr,Altschuler RA,Godfrey DA

更新日期：1991-03-01 00:00:00

abstract：:Several studies have demonstrated that treatment with intracochlear chronic electrical stimulation (CES) protects spiral ganglion cells (SGCs) from degeneration in deafened animals. Other studies could not confirm this effect of CES. The present study examined whether CES in a mode as presented in cochlear implant use...

journal_title：Hearing research

authors： Agterberg MJ,Versnel H,de Groot JC,van den Broek M,Klis SF

更新日期：2010-10-01 00:00:00

abstract：:This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...

journal_title：Hearing research

authors： Hudspeth AJ,Martin P

更新日期：2010-01-30 00:00:00

abstract：OBJECTIVE:This paper introduces a new method to calculate relative risks of elevated hearing thresholds, at various ages and frequencies, between a study population and ISO1999:2003: Annex A Screened, Annex B Unscreened and ISO1999 Section 5.3 adjustment for noise exposure using Annex A Screened data. We demonstrate th...

journal_title：Hearing research

authors： Guest M,Boggess M,Attia J,SHOAMP study team and Scientific Advisory Committee.

更新日期：2012-03-01 00:00:00

abstract：:Sharp spatial selectivity is critical to auditory performance, particularly in pitch-related tasks. Most contemporary cochlear implants have employed monopolar stimulation that produces broad electric fields, which presumably contribute to poor pitch and pitch-related performance by implant users. Bipolar or tripolar ...

journal_title：Hearing research

authors： Zhu Z,Tang Q,Zeng FG,Guan T,Ye D

更新日期：2012-01-01 00:00:00

abstract：:The effect of glutathione co-therapy on the expression of gentamicin ototoxicity was tested in pigmented guinea pigs. The first group of animals was injected with gentamicin (100 mg/kg body weight/day) for two weeks followed by 10 weeks of rest. A second group received glutathione by gastric gavage immediately prior t...

journal_title：Hearing research

authors： Garetz SL,Altschuler RA,Schacht J

更新日期：1994-06-15 00:00:00

abstract：:Averaged auditory evoked potentials (AEPs) to bilaterally presented 100 Hz click trains were recorded from multiple sites simultaneously within Heschl's gyrus (HG) and on the posterolateral surface of the superior temporal gyrus (STG) in epilepsy-surgery patients. Three auditory fields were identified based on AEP wav...

journal_title：Hearing research

authors： Brugge JF,Volkov IO,Oya H,Kawasaki H,Reale RA,Fenoy A,Steinschneider M,Howard MA 3rd

更新日期：2008-04-01 00:00:00

abstract：:A growing body of evidence implies that the dorsal cochlear nucleus (DCN) plays an important role in tinnitus. To test the hypothesis that the rostral output of the DCN is necessary for the experience of chronic tinnitus, the dorsal DCN and the dorsal acoustic stria of rats with psychophysical evidence of tinnitus was...

journal_title：Hearing research

authors： Brozoski TJ,Bauer CA

更新日期：2005-08-01 00:00:00

abstract：:Functional magnetic resonance imaging is a noninvasive and nonradioactive method for the detection of focal brain activity. In the present study the auditory cortex was investigated in nine normal subjects who were binaurally stimulated using pulsed sine tones of 500 Hz and 4000 Hz. The BOLD (blood oxygenation level d...

journal_title：Hearing research

authors： Bilecen D,Scheffler K,Schmid N,Tschopp K,Seelig J

更新日期：1998-12-01 00:00:00

abstract：:Healthy guinea pigs were exposed to broad band noise at levels between 95 and 115 dBA for 7 days. A significant decrease of the sound-induced cochlear responses, together with a substantial increase of the endocochlear potential, was observed in guinea pigs exposed to noise at 105 or 115 dBA. Microsamples of the endol...

journal_title：Hearing research

authors： Konishi T,Salt AN,Hamrick PE

更新日期：1979-12-01 00:00:00

abstract：:Periodicity coding was studied in primary auditory cortex of the ketamine anesthetized cat by simultaneously recording with two electrodes from up to 6 neural units in response to one second long click trains presented once per 3 s. Trains with click rates of 1, 2, 4, 8, 16 and 32/s were used and the responses of the ...

journal_title：Hearing research

authors： Eggermont JJ

更新日期：1991-11-01 00:00:00

abstract：:Size and bilateral asymmetry (i.e. size difference between the left and the right hand side) of inner ear otoliths of larval mouthbreeding cichlid fish were determined during the ontogenetic development of larvae from hatching to the free swimming stage. Animals of two batches were raised in aquarium hatch baskets. Th...

journal_title：Hearing research

authors： Anken RH,Werner K,Ibsch M,Rahmann H

更新日期：1998-07-01 00:00:00

abstract：:Most investigators place reflective beads on the basilar membrane to measure its vibration with optical methods. It is therefore important to find out if the beads faithfully follow the motion of the structures on which they are placed. Vibration of the beads on the basilar membrane and basilar membrane adjacent to th...

journal_title：Hearing research

authors： Khanna SM,Ulfendahl M,Steele CR

更新日期：1998-02-01 00:00:00