Abstract：
:Stress can be a significant factor influencing ear pathologies and is often reported to trigger the symptoms of Meniere's disease. Both physiological and psychological stress provokes the release of prolactin from the pituitary thus allowing the classification of prolactin as a major stress hormone. We investigated the level of the stress hormone prolactin in a Swedish population with early symptoms of Meniere's disease. The median prolactin level in the Meniere patients (n=33) was not significantly different from that of non-Meniere patients (n=23). However, in the Meniere group one female (90 year old) had prolactin levels in the upper normal range for women, one male (77 year old) had prolactin levels above the normal limit for men, and a third patient (76 year old female) presented hyperprolactinemia with more than twice the normal level. MRI confirmed a pituitary adenoma in this patient. This study provides further support for the recent report of hyperprolactinemia in some patients with long-standing Meniere's disease and presenting incapacitating vertigo in France. The data emphasize the likely implication of stress in this pathology where the stress hormone prolactin is likely to represent one actor in a complex hormonal imbalance affecting the inner ear.
journal_name
Hear Resjournal_title
Hearing researchauthors
Falkenius-Schmidt K,Rydmarker S,Horner KCdoi
10.1016/j.heares.2004.11.015keywords:
subject
Has Abstractpub_date
2005-05-01 00:00:00pages
154-8issue
1-2eissn
0378-5955issn
1878-5891pii
S0378-5955(04)00399-5journal_volume
203pub_type
杂志文章相关文献
HEARING RESEARCH文献大全abstract：:Age pigment in the sensory and supporting cells was a prominent characteristic distinguishing old saccules from young. However, the pigment was not distributed uniformly throughout the sensory epithelium but displayed cell-specific patterns of accumulation. The highest cytoplasmic volume density was in the old support...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(89)90038-5
更新日期：1989-01-01 00:00:00
abstract：:Although the neural mechanisms underlying pitch perception are not yet fully understood, there is general agreement that place and temporal representations of pitch are both used by the auditory system. This paper describes a neural network model of pitch perception that integrates both codes of pitch and explores the...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2016.11.005
更新日期：2017-02-01 00:00:00
abstract：:Binaural hearing confers many beneficial functions but our understanding of its underlying neural substrates is limited. This study examines the bilateral synaptic assemblies and binaural computation (or integration) in the central nucleus of the inferior colliculus (ICc) of the auditory midbrain, a key convergent cen...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2017.09.007
更新日期：2017-11-01 00:00:00
abstract：:Gene therapy using virus vectors to treat hereditary diseases has made remarkable progress in the past decade. There are FDA-approved products for ex-vivo gene therapy for diseases such as immunodeficiencies (e.g., SCID), and in vivo gene therapy for a rare blindness and neuro-muscular disease. Gene therapy for heredi...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2020.107927
更新日期：2020-09-01 00:00:00
abstract：:The vibration characteristics (amplitude and phase as a function of frequency) of the tympanic membrane in the grass frog were measured using a laser-doppler velocity meter. It was tested to what extent the frog's acoustic system behaves as a pressure gradient receiver. This might clarify how the frog localizes sound....
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(84)90018-2
更新日期：1984-05-01 00:00:00
abstract：:Listening to speech in noise can be effortful but when motivated people seem to be more persevering. Previous research showed effects of monetary reward on autonomic responses like cardiovascular reactivity and pupil dilation while participants processed auditory information. The current study examined the effects of ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2018.07.011
更新日期：2018-09-01 00:00:00
abstract：:Auditory cortex exhibit a capacity of modulating the functions of subcortical auditory nuclei and even inner ear through descending pathways. The cochlear nucleus (CN), which acts as the gateway from the auditory periphery to the central auditory system, is also subjected to corticofugal modulation. Cortical modulatio...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2018.12.013
更新日期：2019-03-01 00:00:00
abstract：:Although gap junctions occur in auditory and vestibular systems, their function is unclear. Here we present evidence for gap junctional communication in transmitting mechanosensory signals in a sea anemone model system. Hair bundles on anemone tentacles are vibration-sensitive mechanoreceptors that regulate discharge ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(00)00047-2
更新日期：2000-06-01 00:00:00
abstract：:This paper reviews the contributions of von Békésy to psychoacoustics, comparing his findings and interpretations to those that have emerged since his work. The areas covered include the perception of pitch for pure tones and complex tones, the effect of frequency on the apparent location of pure tones, estimation of ...
journal_title：Hearing research
pub_type： 历史文章,杂志文章,评审
doi：10.1016/j.heares.2012.04.009
更新日期：2012-11-01 00:00:00
abstract：:Inner hair cell (IHC) recordings were made from second turn of the guinea pig cochlea where characteristic frequencies are approximately 4000 Hz. In order to compare IHC responses with rate suppression measured in the auditory nerve, suppressors were introduced that produced little or no response in the hair cell. The...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(92)90052-o
更新日期：1992-06-01 00:00:00
abstract：:The IgG1 mouse monoclonal antibody (MAb) KHRI-3, binds to an antigen of 65-68 kDa expressed on inner ear supporting cells in guinea pigs. We previously showed [Nair et al. (1995) Monoclonal antibody induced hearing loss. Hear. Res. 83, 101-113] that mice carrying the KHRI-3 hybridoma develop high frequency hearing los...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(97)00024-5
更新日期：1997-05-01 00:00:00
abstract：:The Federal Food and Drug Administration, or FDA is generally considered a powerful gatekeeper, able to deliver or withhold life-saving cures and create or destroy economic windfalls. As the decades go by, and technologies, diseases, public health demands, and politics evolve, we can identify patterns of change, actio...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2016.11.006
更新日期：2017-06-01 00:00:00
abstract：:To assess the effects of extracochlear electrical stimulation on cochlear structure, guinea pigs were implanted and stimulated with single middle ear electrodes either at round window or promontory sites, and their cochleae examined by transmission electron microscopy. Implanted but unstimulated, or unimplanted contro...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(87)90214-0
更新日期：1987-11-01 00:00:00
abstract：:Light microscopy and immunohistochemical analyses of a freshly prepared human cochlea, removed at meningioma skull base surgery, were performed with particular emphasis on synaptophysin (SY) reactivity. Synaptophysin, a 38-kDa glycoprotein, is one of the most abundant integral membrane proteins of small presynaptic ve...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(03)00228-4
更新日期：2003-11-01 00:00:00
abstract：:Previous investigations have shown that a subset of inferior colliculus neurons, which have been designated type O units, respond selectively to isolated features of the cat's head-related transfer functions (HRTFs: the directional transformation of a free-field sound as it propagates from the head to the eardrum). Ba...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2008.01.008
更新日期：2008-04-01 00:00:00
abstract：:We used whole cell voltage clamp recordings from neurones in rat auditory brainstem slices to study the Ca(2+) channel types involved in triggering synaptic glutamate and glycine release in the medial superior olivary nucleus. Glutamate release from the anterior ventral cochlear (aVCN) bushy neurone synapse did not in...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(01)00378-1
更新日期：2001-12-01 00:00:00
abstract：:Several studies have shown that treatment with various neurotrophins protects spiral ganglion cells (SGCs) from degeneration in hair-cell deprived cochleas. In most of these studies the neurotrophins are delivered by means of intracochlear delivery methods. Recently, other application methods that might be more suited...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2010.10.003
更新日期：2011-02-01 00:00:00
abstract：:The field L complex is thought to be the highest auditory centre and the input in the song vocal nuclei. Different anatomical and functional subdivisions have been described in field L. Auditory neurons of field L are well activated by natural sounds and especially by species-specific sounds. A complex sound coding ap...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2005.01.008
更新日期：2005-09-01 00:00:00
abstract：:This study used immunocytochemical markers for various classes of glial cells to investigate the relationship between glial elements and microcysts in the gerbil auditory system at the light and electron microscopic level. Monoclonal antibodies S-100, GFAP and Rip were used on tissue from 3- and 12-month old animals a...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(93)90226-q
更新日期：1993-05-01 00:00:00
abstract：:The hair cells of the vertebrate inner ear posses active mechanical processes to amplify their inputs. The stereocilia bundle of various vertebrate animals can produce active movements. Though standard stereocilia-based mechanisms to promote amplification persist in mammals, an additional radically different mechanism...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2009.12.028
更新日期：2011-03-01 00:00:00
abstract：:We studied hair cell regeneration in the crista ampullaris of the lizard Podarcis sicula both in untreated animals and at early and late time intervals following a single high dose of gentamicin. The study was carried out using the S-phase marker 5-bromo-2'-deoxyuridine. Our ultrastructural and immunofluorescence stud...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(03)00040-6
更新日期：2003-04-01 00:00:00
abstract：:Wavelength-swept optical coherence tomography (OCT) was used to scan the structure of cadaveric chinchilla ears in three dimensions with high spatial resolution and measure the sound-induced displacements of the entire OCT-visible lateral surfaces of the ossicles in the lateral-to-medial direction. The simultaneous me...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2020.108056
更新日期：2020-10-01 00:00:00
abstract：:Immunocytochemical methods were used to examine cryosections of the embryonic and neonatal chicken cochlea in order to study the histological distribution of the Na+,K+-ATPase molecule during maturation. In complementary studies the Na+,K+-ATPase capacity of microdissected freeze-dried substructures of the cochlea was...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(87)90212-7
更新日期：1987-11-01 00:00:00
abstract：:Several studies have demonstrated that treatment with intracochlear chronic electrical stimulation (CES) protects spiral ganglion cells (SGCs) from degeneration in deafened animals. Other studies could not confirm this effect of CES. The present study examined whether CES in a mode as presented in cochlear implant use...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2010.06.015
更新日期：2010-10-01 00:00:00
abstract：:Kanamycin (KM)-induced changes in expression of the gene for glutamate-aspartate transporter (GLAST) in the rat cochlea were analyzed by Northern blotting. With the administration of KM (600 mg/kg/day) once daily for 20 days, the expression of GLAST mRNA gradually increased and reached a peak on day 20. Although the e...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(99)00050-7
更新日期：1999-07-01 00:00:00
abstract：:Six utricular hair bundles from a red-eared turtle are modeled using 3-D finite element analysis. The mechanical model includes shear deformable stereocilia, realignment of all forces during force load increments, and tip and lateral link inter-stereocilia connections. Results show that there are two distinct bundle t...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2004.06.006
更新日期：2004-11-01 00:00:00
abstract：:The responses to two identical, consecutive pure tone stimuli with varying inter-stimulus intervals (delta ts) were measured for 89 neurons in the cochlear nucleus of the anaesthetised guinea pig. We observed two main effects; either a decrease (suppression) or an increase (facilitation) in response to the second tone...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/j.heares.2005.12.005
更新日期：2006-02-01 00:00:00
abstract：:Increase in spontaneous neural activity after noise-induced hearing loss has frequently been associated with the phenomenon of tinnitus. Eighteen juvenile and adult cats were exposed for 2 h to a 6 kHz tone with an intensity of 115 dB SPL at the cat's head. Seven non-exposed littermates and seven other normal hearing ...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/s0378-5955(03)00074-1
更新日期：2003-06-01 00:00:00
abstract：:Spontaneous synaptic activity in afferent fibers innervating hair cells of the lateral line organ was monitored with micropipettes at visually identified locations near the peripheral terminations of the fibers. Spontaneous action potentials as well as spontaneous excitatory post-synaptic potentials (EPSPs) were obser...
journal_title：Hearing research
pub_type： 杂志文章
doi：10.1016/0378-5955(90)90023-i
更新日期：1990-02-01 00:00:00
abstract：:Spatial hearing skills are essential for children as they grow, learn and play. These skills provide critical cues for determining the locations of sources in the environment, and enable segregation of important sounds, such as speech, from background maskers or interferers. Spatial hearing depends on availability of ...
journal_title：Hearing research
pub_type： 杂志文章,评审
doi：10.1016/j.heares.2016.01.003
更新日期：2016-08-01 00:00:00
