Abstract:
INTRODUCTION:Considering that dyslipidaemia is an important factor for cardiovascular diseases, target lipid levels are rarely reached in everyday clinical practice. OBJECTIVE:The objective of this study was to evaluate how often we achieve the treatment goals for the lipid parameters in the diabetic and non-diabetic patients after the previous myocardial infarction (MI). METHODS:The survey included 118 patients (84 males and 34 females), mean age 59.38 +/- 9.86 years, 34 (28.8%) of them diabetics, with the history of MI in the previous 3 years. The patients were selected from the database of multicentre prospective interventional study "Secondary prevention of coronary heart disease and cerebrovascular diseases", conducted in 2005 on 1,189 patients in Serbia. The patients were further followed in the period from 18 (5th visit) and 36 months (6th visit) after inclusion into the study from 2005-2008. Their lipid status, the use of lipid-lowering drugs, and the independent prognostic factors for major adverse coronary events were identified. In the beginning of the study, all patients were informed about the importance of lifestyle change and active approach to treatment. The accomplishment of secondary preventive measures was estimated on the basis of the European guidelines on secondary prevention of the coronary heart disease. RESULTS:Three years after introduction of the preventive measures, diabetics had a higher prevalence of the target levels of the total cholesterol (21.2% vs. 7.6%) and HDL-cholesterol than non-diabetics (100% vs. 87.3%) (p < 0.05). Non-diabetics had significantly higher prevalence of the target levels of LDL-cholesterol than diabetics (19% vs. 3%) (p < 0.05). No significant differences were found in the prevalence of the treatment goals of triglycerides in diabetic (42.4%) and non-diabetic patients (60.8%) (p > 0.05). At the end of the study, after applying secondary prevention measures, 27.3% of diabetics did not use lipid-lowering drugs. The percentage of non-diabetics using no lipid-lowering drugs was lower (20.3%), but the difference was not statistically significant (p > 0.05). By using the method Enter Cox regression multivariant analysis, the change in the level of triglycerides, total and LDL-cholesterol were singled out as independent prognostic factors for major adverse coronary events. CONCLUSION:Our study has shown high prevalence of increased plasma concentrations in the total, LDL-cholesterol and triglycerides and low plasma concentrations of HDL-cholesterol, as well as the insufficient use of lipid-lowering drugs in diabetic and non-diabetic patients with previous MI. Decreasing the total cholesterol and increasing the HDL-cholesterol are significant, decreasing of triglycerides and LDL-cholesterol does not suffice. Therefore, secondary prevention measures of cardiovascular events should be intensified, especially in patients with diabetes.
journal_name
Srp Arh Celok Lekjournal_title
Srpski arhiv za celokupno lekarstvoauthors
Aleksić E,Stamenković R,Lapcević M,Deljanin-Ilić M,Djordjević D,Tasić Idoi
10.2298/sarh1102030asubject
Has Abstractpub_date
2011-01-01 00:00:00pages
30-6issue
1-2eissn
0370-8179issn
2406-0895journal_volume
139pub_type
杂志文章abstract::Pelvic inflammatory disease (PID) is polymicrobial infection in women characterized by inflammation of the upper genital tract, including endometritis, salpingitis, pelvic peritonitis, occasionally leading to the formation of tubo-ovarian abscess (TOA). PID primarily affects young, sexually active women, and it is hig...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章,评审
doi:10.2298/sarh1010658t
更新日期:2010-09-01 00:00:00
abstract::This is a survey of the recent data on glomerular mesangium. Besides its structural role as the main part of the capillary network, mesangial cells play a certain role in the formation and degradation of the extracellular matrix, in the spread and processing of circulating macromolecules, and in the regulation of glom...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章,评审
doi:
更新日期:1994-03-01 00:00:00
abstract::There is a variety of terms related to the classification of voice disorders still in use. The basic characteristics are discussed. Classification according to Perello, modified by the author, is recommended. On the basis of this classification, the "basic diagnosis" is suggested, with all necessary diagnostic procedu...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章,评审
doi:
更新日期:1995-05-01 00:00:00
abstract:INTRODUCTION:Systemic lupus erythematosus is a multisystemic autoimmune disease characterized by various clinical manifestations, as well as unpredictable course and therapy response. Lupus nephritis is a severe manifestation of the disease, significantly influencing its prognosis. Since the pathogenesis of lupus nephr...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:2002-08-01 00:00:00
abstract::Detrusor tunnelling is an extravesical surgical procedure of ureteral reimplantation. It is surely the least traumatic method of surgical correction of vesico-ureteral reflux because antireflux mechanism is achieved with minimal detrusor muscle dissection. This procedure simplifies implantation of dilated ureters, dou...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract:INTRODUCTION:It has been shown that depolarization disorders, autonomic dysfunction, and systolic dysfunction of the left ventricle are associated with sudden cardiac death after myocardial infarction. OBJECTIVE:The objective of study was to examine the prognostic value of the most important predictors in the first we...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh0612482m
更新日期:2006-11-01 00:00:00
abstract::Medical teaching at School in Belgrade started in 1863 when forensic medicine became an oblicatory subject for law students. In 1865 the Serbian physician Joachim Medovitsh (1815-1893) published the first medical textbook "Forensic medicine for lawyers" in Serbia. It appeared more than fifty years before foundation of...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 传,历史文章,杂志文章
doi:
更新日期:2001-09-01 00:00:00
abstract::Mastitis carcinomatosa (inflammatory carcinoma) is a very rare form of breast cancer, with a rapid progress, generalisation and dissemination into the vital organs, and lethal issue. Inflammatory carcinoma of the breast (ICB) accounts for 1 to 4 per cent of all breast carcinomas. Only 3 to 6 per cent of patients survi...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章,评审
doi:
更新日期:1990-03-01 00:00:00
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journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh0808419v
更新日期:2008-07-01 00:00:00
abstract:INTRODUCTION:Nosocomial infections (NIs) are a serious health problem in hospitals worldwide and are followed by a series of consequences, medical, judicial, ethical and economic. OBJECTIVE:The main aim of this study was to assess the magnitude of NIs at the Clinical Centre in Kragujevac. METHODS:A prevalence study o...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh1006337i
更新日期:2010-05-01 00:00:00
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journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章,评审
doi:10.2298/sarh1408498d
更新日期:2014-07-01 00:00:00
abstract::The study included 1,825 persons, aged from 18 to 65 years. A representative sample was formed of 1,325 persons who donated blood for the first time, and of 500 persons who donated blood five or more times till the moment of investigation. Among blood donors in the Republic of Serbia, regardless the number of blood do...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract::We investigated the incidence of thyroid auto-antibodies and their relationship to antigastric antibodies in 20 euthyroid patients with pernicious anaemia. To evaluate possible thyroid dysfunction we also measured total level of thyroid hormones (TT3 and TT4) and TSH in our patients. Histologic evidence of autoimmune ...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract::Blood pressure measurements obtained in a physicians office may not reflect the patients blood pressure during the whole day. Ambulatory blood pressure monitoring provides information about blood pressure during normal daily activities and night sleep. Further, the results of ambulatory blood pressure monitoring are i...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:1997-05-01 00:00:00
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journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh1210563k
更新日期:2012-09-01 00:00:00
abstract:INTRODUCTION:Successful riddle solving requires recognition of the meaning of words, attention, concentration, memory, connectivity and analysis of riddle content, and sufficiently developed associative thinking. OBJECTIVE:The aim of the study was to determine the ability to solve riddles in stroke patients who do or ...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:2016-03-01 00:00:00
abstract::Diagnostics in patients with the acute coronary syndromes (ACS) is becoming even more complex with the increase of number of available options. In addition, the number of treatment options accessible to patients with ACS keeps on growing rapidly. Physicians must now choose from a wide variety of antiplatelet and antit...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章,评审
doi:
更新日期:2006-03-01 00:00:00
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journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
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journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
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journal_title:Srpski arhiv za celokupno lekarstvo
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journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
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journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:1995-11-01 00:00:00
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journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:1996-05-01 00:00:00
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journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh1106322c
更新日期:2011-05-01 00:00:00
abstract:INTRODUCTION:Lipid peroxidation and antioxidant systems are important factors affecting the metabolism of lipoproteins in diabetes mellitus. OBJECTIVE:The aim of this study was to investigate the lipid and antioxidant parameters in type II diabetes mellitus patients, and also to determine the effect of diabetic compli...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
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更新日期:2007-03-01 00:00:00
abstract::A patient, aged 28, was admitted to the Department of Urology of the Military Medical Academy in Belgrade, for the operation of the right adrenal gland tumour. The adrenal gland tumour was first diagnosed as an inactive hormonal tumour. Intraoperatively it was found in retroperitoneal area, over the right adrenal glan...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:1991-09-01 00:00:00
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journal_title:Srpski arhiv za celokupno lekarstvo
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doi:
更新日期:2002-05-01 00:00:00
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journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
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更新日期:2014-09-01 00:00:00
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journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:1991-09-01 00:00:00
abstract::What is translation--a craft, an art, a profession or a job? Although one of the oldest human activities, translation has not still been fully defined, and it is still young in terms of an academic discipline. The paper defines the difference between translation and interpreting and then attempts to find the answer to...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:2013-07-01 00:00:00