[Early risk predictors of sudden cardiac death after myocardial infarction: results of follow up of 881 patients].

Abstract:

INTRODUCTION:It has been shown that depolarization disorders, autonomic dysfunction, and systolic dysfunction of the left ventricle are associated with sudden cardiac death after myocardial infarction. OBJECTIVE:The objective of study was to examine the prognostic value of the most important predictors in the first week after myocardial infarction. METHOD:Study included 881 patients who were followed up from 1 to 60 months. During the first week after myocardial infarction, following examination were performed: ECG with standard leads and X, Y, Z orthogonal leads, vectorcardiogram, QT interval, late potentials, short-time spectral analysis of RR variability, nonlinear (Poincaré plot) analysis and echocardiogram. RESULTS:In univariate analysis, the following parameters measured on the first day were important predictors of sudden cardiac death: lower LF/HF ratio (<1.5) (p = 0.000), T wave inversion in X lead (p = 0.000), high P wave in D2 lead (p=0.030), and diminished systolic function (p = 0.000). In multivariate analysis, the following parameters were significant risk predictors: T wave inversion in X lead, lower LF/HF ratio, positive late potentials and the left ventricle systolic dysfunction. CONCLUSION:The parameters of the left ventricle systolic disfunction with sympathicovagal imbalance and electric instability are the key risk predictors in the first few days after myocardial infarction.

journal_name

Srp Arh Celok Lek

authors

Milovanović B,Krotin M,Vuković D,Bisenić V,Mirjanić T,Nikolić S

doi

10.2298/sarh0612482m

subject

Has Abstract

pub_date

2006-11-01 00:00:00

pages

482-7

issue

11-12

eissn

0370-8179

issn

2406-0895

journal_volume

134

pub_type

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