Abstract：
INTRODUCTION:Lipid peroxidation and antioxidant systems are important factors affecting the metabolism of lipoproteins in diabetes mellitus. OBJECTIVE:The aim of this study was to investigate the lipid and antioxidant parameters in type II diabetes mellitus patients, and also to determine the effect of diabetic complications on these parameters. METHOD:Lipid status, Oxidized LDL cholesterol, glutathione peroxidase (GSH-Px), superoxide dismutase (SOD) and plasminogen activator inhibitor (PAI-1) levels in plasma of 50 type II diabetic patients were measured with commercially available kits. RESULTS:The results showed only statistically significant higher levels of triglycerides (3.12 +/- 3.9 mmol/l) in diabetics compared with the controls. Ox-LDL cholesterol (84.7 +/- 16.9 mmol/l) and SOD activities (913.4 +/- 120.3 U/gHb) in type 2 diabetes mellitus were higher than those of the controls, but there was no statistical significance. On the other hand, in patients with diabetes mellitus and complications, LDL cholesterol, PAI-1, SOD and GSH-Px activities were higher but not significantly than those without complications. Triglycerides and Ox-LDL cholesterol were lower in the group of diabetic patients with complications in comparison to the group without complications. CONCLUSION:These results indicate that antioxidant status may be affected in type II diabetic patients and that the rise in some enzyme activities could be a compensatory mechanism to prevent tissue damage. Our results suggest that the rise in PAI-1 in type II diabetics with complications may be a good marker of vascular endothelial dysfunction.
journal_name
Srp Arh Celok Lekjournal_title
Srpski arhiv za celokupno lekarstvoauthors
Kostić N,Caparević Z,Ilić Sdoi
10.2298/sarh0704143ksubject
Has Abstractpub_date
2007-03-01 00:00:00pages
143-6issue
3-4eissn
0370-8179issn
2406-0895journal_volume
135pub_type
杂志文章abstract：:Our results of surgery of developmental disorder of the hip (DDH) in older children and adolescents by using the combination of Selter's innominate osteotomy and osteotomy of the superior pubis ramus were presented in this paper, enclosing the period from 1993 to 1995. The study included 11 hips, i.e. 9 patients, aged...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh04s1023b
更新日期：2004-10-01 00:00:00
abstract：INTRODUCTION:Psychiatric treatment in developed countries has significantly changed in the last few decades, with a significant shortening of the duration of hospitalization. Numerous West European countries are undertaking health system reforms to improve treatment efficiency. OBJECTIVE:The aim of the study was to pr...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：2011-12-01 00:00:00
abstract：:A sudden onset of the syndrome Guillain-Barré in 48-year-old woman presenting as an acute motor neuropathy was associated with antibodies against ganglioside GM1 detected by ELISA. The neurological examination revealed flaccid quadriplegia without affection of the sensory system, and the additional investigation showe...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1996-07-01 00:00:00
abstract：:In the past two decades a huge progress was achieved in the treatment of malignant diseases in children. The cyclical chemotherapy combined with surgery and radiotherapy gave very good results. However, the contribution of chemotherapy to paediatric neuro-oncology was not as great is it was to other branches of paedia...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：1989-11-01 00:00:00
abstract：:We describe a 51-year old-woman with haemorrhagic syndrome manifested as spontaneous bruising, and prolonged and abundant menstrual bleeding. She had hed these symptomes for six months prior to admission, but denied lifelong bleeding tendency. Gynaecological examination revealed a myomatouse uterus. Occasionally, the ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1988-07-01 00:00:00
abstract：INTRODUCTION:Carotid endarterectomy is a safe and reliable surgical procedure to treat the narrowing of the internal carotid artery greater than 70%. One of the most serious complications of surgical wound after endarterectomy is an infection caused by methicillin-resistant Staphylococcus aureus (MRSA) which is accompa...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1104225p
更新日期：2011-03-01 00:00:00
abstract：INTRODUCTION:Congenital nephrotic syndrome is usually presented with heavy proteinuria, hypoproteinaemia, oedema and hyperlipidaemia in a child from its birth until the age of 3 months. Aetiology of the disease is mutation in the relevant gene or it develops secondary to various infections. The most common form of cong...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh08s4307s
更新日期：2008-12-01 00:00:00
abstract：:Type and technique of anesthesia have an important effect on per operative surgical course. The aim of the study was prospective analyses of advantages of combined spinal, epidural and general anesthesia (CSEGA) versus general anesthesia (GA) in abdominal surgery according to: 1. operative course (haemodynamic stabili...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.2298/sarh0306232m
更新日期：2003-05-01 00:00:00
abstract：:The factors that determine the transfer of medicine from mothernal blood to breast milk are the relative molecular mass of the substance, liposolubility, plasma half-life, binding to plasma proteins, pKa, the rate of metabolism and the dose taken by the breast feeding mother. The transfer of large number of medicines ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1995-06-01 00:00:00
abstract：:In recent years, the development of new surgical techniques in uterus myoma treatment have reduced operative trauma significantly. Our objective was to present operative technique--vaginal myomectomy, making a prospective clinical study where we have evaluated the operative and postoperative period after intentive dia...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0402018m
更新日期：2004-01-01 00:00:00
abstract：:Solid and cystic-papillary tumour of the pancreas is a rare neoplasm. About 420 cases seem to have been reported as yet. It appears almost exclusively in young women, although it may appear in males in all ages. This is a tumour of benign or low malignant potential with vary rare invasion of surrounding tissues and or...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：2000-11-01 00:00:00
abstract：:There is a variety of terms related to the classification of voice disorders still in use. The basic characteristics are discussed. Classification according to Perello, modified by the author, is recommended. On the basis of this classification, the "basic diagnosis" is suggested, with all necessary diagnostic procedu...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：1995-05-01 00:00:00
abstract：INTRODUCTION:Alveolar adenoma belongs to the group of benign epithelial tumours. Histogenesis of alveolar adenoma is a combination of proliferation of alveolar pneumocytes and fibrous tissue originating from septal mesenchyma. CASE OUTLINE:A sixty-nine-year old female patient was hospitalizied for clinical examination...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0708461s
更新日期：2007-07-01 00:00:00
abstract：INTRODUCTION:Hydatidosis is a human disease caused by the larval form of Echinococcus granulosus. All organs in the human body may be affected by hydatid disease, but excluding liver and lungs, all other organs are considered as uncommon locations. Hydatid disease located in the psoas muscle is uncommon. CASE OUTLINE:...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1008502b
更新日期：2010-07-01 00:00:00
abstract：:During the study of the pathological significance of circulating endothelin (ET) in acute renal failure (ARF) we measured ET in 7 children (mean age 8.8+4.4 years) with ARF in the most severe phase, and 3.7+3.5 months later in the recovery period. Twenty-seven healthy children (mean age 11.1+/- 6.3 years) were include...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1995-11-01 00:00:00
abstract：INTRODUCTION:Enlarged axillary lymph nodes are often found during routine examinations. They are usually circular, oval, lobular, smaller than 1 cm, with typically changed fat centers. The condition of axillary lymph nodes in breast cancer is of great importance for timely diagnosis, because its metastatic spread is a ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1997-03-01 00:00:00
abstract：INTRODUCTION:Cesarean delivery is the most common obstetric surgery today. Improvement of operative techniques, anaesthesia, care and transfusion has contributed to the safety of the procedure and expansion of indications. The operative technique usually consists of opening the abdominal wall by inferior transverse inc...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,随机对照试验
doi：10.2298/sarh08s2109v
更新日期：2008-05-01 00:00:00
abstract：:Secretory otitis media is defined as a fluid in the middle ear without signs or symptoms of infection. As the aetiology and pathogenesis of the disease are unknown, and as it affects children aged from 3 to 12 years, treatment procedures proposed for management of secretory otitis media, are not uniform. Some authors ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1998-07-01 00:00:00
abstract：:This is a case report of 26-year old, advanced university student of the Faculty of Science, Department of Mathematics, single. He has never been a psychiatric patient, but being unable to suppress the gambling impulse, he presented for treatment, on his own initiative, to the outpatient department. Patient met the cr...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0602060m
更新日期：2006-01-01 00:00:00
abstract：INTRODUCTION:Gastroesophageal reflux is a frequent disease which has a significant influence on the development of dental erosions. OBJECTIVE:The aim of this research was to determine the frequency of dental erosions among the patients with gastroesophageal reflux, as well as to verify the most common symptoms of gast...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1006292s
更新日期：2010-05-01 00:00:00
abstract：INTRODUCTION:Mesenchymal stem cells (MSCs) are a promising tool for regenerative medicine, but due to the heterogeneity of their populations, different sources and isolation techniques, the characteristics defining MSCs are inconsistent. OBJECTIVE:The aim of this study was to compare the characteristics of MSCs derive...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1304178t
更新日期：2013-03-01 00:00:00
abstract：:Between 1980 and 1985 we treated 21 patients with primary spinal cord tumors. There were two diffuse and ten localized ependymoma, six low grade astrocytoma and three malignant glioma. Surgery consisted of total resection in six patients, subtotal resection in three and biopsy in twelve patients. Radiation doses range...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：:One of the most frequent causes of deterioration of chronic obstructive lung diseases is the infection. The existence of microorganisms resistant to antibiotics is becoming an increasingly serious therapeutical problem. Kinolones have a wider spectrum of action than the majority of other antibiotics, with strong effec...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：INTRODUCTION:Nutritional abnormalities have one of the most important systematic effects on chronic obstructive pulmonary disease (COPD). A relationship between COPD and obesity has been observed and recognised. In COPD patients, beside changes in the total body weight, changes in body composition are also possible wit...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1106322c
更新日期：2011-05-01 00:00:00
abstract：INTRODUCTION:Total anomalous pulmonary venous connection (TAPVC) is a rare congenital heart disease and in some variants represents the only true surgical emergency in congenital heart surgery. Basic anatomical characteristic of this anomaly is an abnormal connection of pulmonary veins with systemic venous circulation....
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1404164m
更新日期：2014-03-01 00:00:00
abstract：:In the last two decades the clinical and research focus in psychotic disorders has shifted to first episode psychosis, early detection of the prodromal phase of psychosis and an effective integrated treatment model known as "Early Intervention". The first five years of psychosis that is described as a "critical period...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：2007-11-01 00:00:00
abstract：INTRODUCTION:Chronic hepatitis C reduces the quality of life in patients causing fatigue, loss of self-confidence, reduced working capacity, development of depression, emotional problems, and cognitive dysfunction. OBJECTIVE:The aim of the study was to identify the presence of depression in patients with chronic hepat...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1110645p
更新日期：2011-09-01 00:00:00
abstract：:Dr. Lazar K. Lazarević (1851-1890, Julian calendar/1891, Gregorian calendar) was an exceptional Serbian physician, scientist, writer and translator. During his short life and his close to 11-year-long professional career (1879-1890), Dr. Lazarević authored 78 scientific papers and presentations in various branches of ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 历史文章,杂志文章
doi：10.2298/sarh1602111d
更新日期：2016-01-01 00:00:00
abstract：INTRODUCTION:The cardiovascular changes (vascular structure changes, hypertrophy of the left ventricle) contribute to both the increased cardiovascular morbidity and the mortality of essential hypertension. Therefore, modern treatment strategies should not only target blood pressure (BP) reduction but also normalize ca...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,随机对照试验
doi：10.2298/sarh0604106t
更新日期：2006-03-01 00:00:00
abstract：:It is widely accepted that alcohol metabolism passes through different mechanisms: alcohol dehydrogenase (ADH) activity in stomach epithelial cells, activity of ADH in the liver, microsomal-ethanol-oxydizing system (MEOS), hepatocyte catalase activity, and nonoxydizing metabolic pathway (production of fatty acid ethyl...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：1996-09-01 00:00:00
