Abstract：
:We describe a 51-year old-woman with haemorrhagic syndrome manifested as spontaneous bruising, and prolonged and abundant menstrual bleeding. She had hed these symptomes for six months prior to admission, but denied lifelong bleeding tendency. Gynaecological examination revealed a myomatouse uterus. Occasionally, the patient had crops of erythemo-exudative skin lesion which were shown on biopsy to represent urticarial (leukocytoclastic) vasculitis. No evidence of systemic connective tissue disease was found. Haemostasis testing revealed: prolonged bleeding time, decreased platelet adhesiveness to glass beads, lowered FVIII : C, absence of ristocetin-induced platelet aggregation and unmeasurable FVIII : Af and vWf. There was no evidence for an inhibitor to FVIII : C. However, patient's plasma, when mixed ana partes equales with normal plasma, reduced the FVIII : Ag and vWf level to 48% and 46% respectively, as compared to the mixture of normal plasma and buffer. When incubated at room temperature, patient's washed platelets spontaneously released vWf and aggregated in the presence ristocetin. However, when patient's plasma was added aggregation was inhibited. On the basis of these findings and the lack of anamnestic data suggestive of congenital haemorrhagic disorder, we concluded that the patient had acquired von Willebrand disease due to an inhibitor to vWf and FVIII : Ag, associated with urticarial vasculitis and myomatouse uterus. To our knowledge, this association has not yet been reported.
journal_name
Srp Arh Celok Lekjournal_title
Srpski arhiv za celokupno lekarstvoauthors
Elezović I,Rolović Z,Medenica Ljsubject
Has Abstractpub_date
1988-07-01 00:00:00pages
689-97issue
7-8eissn
0370-8179issn
2406-0895journal_volume
116pub_type
杂志文章abstract：:The management of idiopathic nephrotic syndrome (INS) in children includes immunosuppressive and symptomatic treatment. The response to corticosteroid therapy is the best prognostic marker of the disease. The majority of children with INS (about 85%) are steroid-sensitive as they normalize proteinuria within 4 weeks o...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：10.2298/sarh0410352p
更新日期：2004-09-01 00:00:00
abstract：INTRODUCTION:Gastrointestinal stromal tumours are most frequent mesenchimal tumours of the gastrointestinal tract that originate from Cajal's interstitial cells that are most frequently CD-117 positive. Stromal tumours of the stomach are the most frequent mesenchimal tumours of the gastrointestinal tract. Such tumours ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：10.2298/sarh1204216l
更新日期：2012-03-01 00:00:00
abstract：:Subtrochanteric fractures of the femur have a special place because of a significant number of complications following treatment. Powerful loading forces asymmetrically acting to this bone segment, as well as poor vascularization interfere with bone union. There are basically two current approaches in the fixation of ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：10.2298/sarh1108540v
更新日期：2011-07-01 00:00:00
abstract：:Topics of this report concerns the existing elements of informatics related to education of graduate students of the Medical Faculty in Belgrade. The already used practice of this system makes possible effectiveness and quality in this work. System itself contains quite a few data bases: for students, for teaching stu...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1995-09-01 00:00:00
abstract：INTRODUCTION:Balkan endemic nephropathy (BEN) patients maintained with hemodialysis have more severe anemia than patients with other kidney diseases. OBJECTIVE:The aim of the study was to compare the improvement of anemia in BEN patients and those with other kidney diseases during treatment with human recombinant eryt...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1208456l
更新日期：2012-07-01 00:00:00
abstract：:106 patients with acute renal failure (ARF) treated with peritoneal dialysis (PD) for the last 15 years (except for postrenal ARF treated only with HD, or ARF with conservative treatment) were analyzed. The commonest causes were sepsis (3), hemorrhagic fever (17) and complications of some internal or surgical disease ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:The authors present their views of the most frequent difficulties and possible oversights in the diagnosis of chronic secretory otitis on the basis of the treatment of 950 children in all departments. An insidious, subclinical and long-lasting course of chronic secretory otitis, the age of this population and very oft...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：INTRODUCTION:Orofacial pain occurs in various disorders of the orofacial region. OBJECTIVE:The aim of this study was to examine applicability of the visual-analogue scale (VAS) in patients with orofacial pain (model of acute and chronic pain). METHODS:The study involved 60 patients, aged 18-70 years. The first group ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：2013-07-01 00:00:00
abstract：:The diagnosis of hypertension in patients on chronic haemodialysis is not easy because the blood pressure changes as a consequence of therapy (haemodialysis) and attenuated circadian rhythm of blood pressure is often present. The estimation of representative blood pressure levels is difficult because it is not known w...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0210306p
更新日期：2002-09-01 00:00:00
abstract：INTRODUCTION:It has been shown that depolarization disorders, autonomic dysfunction, and systolic dysfunction of the left ventricle are associated with sudden cardiac death after myocardial infarction. OBJECTIVE:The objective of study was to examine the prognostic value of the most important predictors in the first we...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0612482m
更新日期：2006-11-01 00:00:00
abstract：INTRODUCTION:The American otolaryngologist Eagle was the first to describe styloid syndrome in 1937 and the syndrome was named after him (Eagle's syndrome). The original description of two separate syndromes is connected with his name: classical syndrome, which almost constantly occurs after tonsillectomy and carotid a...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0812650p
更新日期：2008-11-01 00:00:00
abstract：:Symptomatic dystonia can be the result of various metabolic, degenerative diseases, the consumption of certain medications or exposure to toxic agents. However, only symptomatic dystonia with focal structural lesion provides a significant "window" for, at least indirect, perception of aetiopathogenesis and pathomorpho...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0206183i
更新日期：2002-05-01 00:00:00
abstract：Introduction:Mucoepidermoid carcinoma, compared to other tumors of salivary glands, occurs in 5–10% of cases. Histopathologically, it is divided into a well differentiated tumor that is of low-grade of malignancy, and a medium and poorly differentiated tumor of high grade of malignancy. Central mucoepidermoid carcinoma...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：2016-09-01 00:00:00
abstract：INTRODUCTION:Chronic hepatitis C reduces the quality of life in patients causing fatigue, loss of self-confidence, reduced working capacity, development of depression, emotional problems, and cognitive dysfunction. OBJECTIVE:The aim of the study was to identify the presence of depression in patients with chronic hepat...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1110645p
更新日期：2011-09-01 00:00:00
abstract：INTRODUCTION:In Serbia, there have been no broad campaigns or educational programs focused on adolescents' sun protection. OBJECTIVE:The aim of the study was to assess whether an educational program would have impact on changes of attitudes and sun-protective behaviors of high school students. More specific aim was to...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,随机对照试验
doi：10.2298/sarh1406330m
更新日期：2014-05-01 00:00:00
abstract：INTRODUCTION:Anti-citrullinated peptides antibodies (ACPA) are present in 80% of sera of rheumatoid arthritis (RA) patients with high specificity for diagnosis and prediction for the development of early erosive arthritis. A few studies have reported a low frequency ACPA in systemic sclerosis (SSc) patients with the pr...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：2012-05-01 00:00:00
abstract：:There is a variety of terms related to the classification of voice disorders still in use. The basic characteristics are discussed. Classification according to Perello, modified by the author, is recommended. On the basis of this classification, the "basic diagnosis" is suggested, with all necessary diagnostic procedu...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：1995-05-01 00:00:00
abstract：:In every patient with congestive heart failure there is a secondary neurohumoral response including increase in serum noradrenaline, renin, angiotensin, aldosteron and antidiuretic hormone or arginine-vasopressin values. Plasma and urine noradrenaline levels are increased proportionally to the severity of ventricular ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
abstract：INTRODUCTION:Adenocarcinoma of the small bowel is a rare gastrointestinal neoplasm usually affecting the distal duodenum and proximal jejunum. Because of their rarity and poorly defined abdominal symptoms, a correct diagnosis is often delayed. CASE OUTLINE:We present a 43-year-old woman admitted at the Clinic for Endo...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1304232i
更新日期：2013-03-01 00:00:00
abstract：INTRODUCTION:Intramural haematoma (IMH) and penetrating aortic ulcers (PAU) are the frequent cause of acute aortic syndrome that is disclosed with a rising frequency due to the development of new diagnostic methods. Different symptoms contribute to clinical misdiagnosis, while changeable locations and unpersuasive diam...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1106380k
更新日期：2011-05-01 00:00:00
abstract：INTRODUCTION:The paper describes a very rare, isolated exocranial complication of the purulent frontal sinus inflammation. Frontal bone osteomyelitis occurs either in the course of an acute episode or during the exacerbation of a chronic disease. By distribution, it can be diffuse or circumscript. It is more common in ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0804154s
更新日期：2008-03-01 00:00:00
abstract：INTRODUCTION:More and more survival of newborns with small or extremely small body mass at birth, as well as increasing percent of prematurely born babies, have emphasized the significance of intracranial haemorrhage problem. Prematurely born infants are under increased risk for strabismus, amblyopia, blinding and hear...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1102006v
更新日期：2011-01-01 00:00:00
abstract：:Eating disorders are considered chronic diseases of civilization. The most studied and well known are anorexia and bulimia nervosa. Anorexia is considered one of the most common psychiatric problems of girls in puberty and adolescence. Due to high mortality and morbidity as well as the increasing expansion of these di...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：2012-09-01 00:00:00
abstract：:Adenomyomatosis of the gall bladder is a rare benign disease in which hypertrophic mucosa makes deep sinuses into hypetrophic muscular layer making, the so called Rokitansky-Aschoff's sinuses. It appears as a localised, segmental or diffuse form of the disease. Localised adnomyomatosis leads to the formation of "tumor...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1994-11-01 00:00:00
abstract：:This is a survey of the recent data on glomerular mesangium. Besides its structural role as the main part of the capillary network, mesangial cells play a certain role in the formation and degradation of the extracellular matrix, in the spread and processing of circulating macromolecules, and in the regulation of glom...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：1994-03-01 00:00:00
abstract：:During the last five years at our Department renal biopsy was carried out in 41 patients with systemic lupus erythematosus. On the basis of the pathologic findings glomerular changes were classified as follows: minimal in 5 patients; mesangial proliferative glomerulonephritis in 11; focal and segmental proliferative g...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：:In the last decades of this century we are witnesses of frequent crises in different parts of the world produced by internal disturbance and wars. These crises, together with natural disasters, poverty and hunger, follow the history of mankind often forcing huge population groups to leave their homes. The harmful heal...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 社论
doi：
更新日期：1997-07-01 00:00:00
abstract：INTRODUCTION:Antioxidant systems are important factors affecting the oxidation of lipoproteins and thereby the progression of atherosclerotic disease. It has been suggested that physical activity might maintain and promote the antioxidant defence capacity against the oxidative stress. Left ventricular dysfunction (LVDD...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0904146k
更新日期：2009-03-01 00:00:00
abstract：:Blood pressure measurements obtained in a physicians office may not reflect the patients blood pressure during the whole day. Ambulatory blood pressure monitoring provides information about blood pressure during normal daily activities and night sleep. Further, the results of ambulatory blood pressure monitoring are i...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1997-05-01 00:00:00
abstract：:The occurrence of abnormal Hodgkin's and Reed-Sternberg cells in the peripheral blood in a patient suffering from Hodgkin's disease has been noticed exceptionally rare in a previous period, and especially rare in last ten years primarily due to successful treatment of this disease. The presence of atypical mononuclear...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0310400m
更新日期：2003-09-01 00:00:00
