Abstract:
:In every patient with congestive heart failure there is a secondary neurohumoral response including increase in serum noradrenaline, renin, angiotensin, aldosteron and antidiuretic hormone or arginine-vasopressin values. Plasma and urine noradrenaline levels are increased proportionally to the severity of ventricular dysfunction, but its reserve is often reduced in the myocardium as well as the density of beta receptors and sensitivity to catecholamines and inotropic responses to the stimulation of adrenergic nerves. Down-regulation of beta-adrenoceptors in the myocardium, verified by the technique of radioligands, with the reduced number of beta-adrenoceptors, is accompanied by the appearance of refractoriness and desensitization to endogenous and exogenous catecholamines. Chronic beta-blockade may improve haemodynamic and clinical function in patients with dilated cardiomyopathy or congestive heart failure, because beta-blockers have potentially beneficial actions: protection of the myocardium from damage by chronic excessive catecholamine stimulation, restoration toward normal of the down-regulated membrane beta-receptor density often seen in heart failure, reduction in the risk of potentially lethal ventricular arrhythmias and beneficial effects on substrate utilization. Our results of investigation in 20 patients with congestive heart failure treated with beta-blockers short and long-term (average 22 months) gave substantial increases in ejection cardiac index and improved functional class and also improved working capacity.
journal_name
Srp Arh Celok Lekjournal_title
Srpski arhiv za celokupno lekarstvoauthors
Trifunović SL,Pavlović Ksubject
Has Abstractpub_date
1992-06-01 00:00:00pages
44-50eissn
0370-8179issn
2406-0895journal_volume
120 Suppl 4pub_type
杂志文章abstract:INTRODUCTION:Obstructive sleep apnoea (OSA) syndrome represents a significant medical problem due to numerous consequences that may follow it. OBJECTIVE:The aim of the study was to analyze morphology of the maxilla in children with mouth breathing, and to assess possible characteristics in persons with marked clinical...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh1204159v
更新日期:2012-03-01 00:00:00
abstract::Rubinstein-Taybi syndrome is a malformation occurring with approximate incidence of 1 per 10,000 live-born children. The diagnosis is usually based on specific facial dysmorphism in neonatal period, as well as on characteristic deformities of the hands and feet. Our study presents a male child who was diagnosed to hav...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh04s1109g
更新日期:2004-10-01 00:00:00
abstract:INTRODUCTION:Successful riddle solving requires recognition of the meaning of words, attention, concentration, memory, connectivity and analysis of riddle content, and sufficiently developed associative thinking. OBJECTIVE:The aim of the study was to determine the ability to solve riddles in stroke patients who do or ...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:2016-03-01 00:00:00
abstract:INTRODUCTION:Moderate ischemic mitral regurgitation (MR) is characterized by significant, symptomatic multivessel coronary disease and mitral regurgitation 2-3+. CASE OUTLINE:A 60-year-old patient was admitted at the Cardiovascular Institute "Dedinje" due to the symptoms of unstable angina pectoris. He survived a myoc...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh0906275t
更新日期:2009-05-01 00:00:00
abstract::Eighty years are passed after the catastrophic epidemics of Typhus and Relapsing Fever in 1915 in Serbia was stopped and put under control. This remarkable achievment was realized in cooperation of the British Military Mission and Serbian health services, one month before the usual seasonal maximum of epidemic wave. T...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 历史文章,杂志文章
doi:
更新日期:1995-11-01 00:00:00
abstract:INTRODUCTION:Hepatic veno-occlusive disease (VOD) is a life threatening complication after stem cells transplantation (SCT). Its prediction, precise diagnosis and treatment remain unclear. OBJECTIVE:Our goals were to determine the incidence, outcome and changes in haemostatic parameters in patients with VOD. Also, we ...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh10s1033j
更新日期:2010-01-01 00:00:00
abstract::Nosocomial infections (NI) are infections acquired in hospitals. The aim of this paper is to describe the organization of NI control program in France. The organization of this program started in 1988 by the formation of the Infection Control Committees in hospitals. Their role has been to organize the surveillance of...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:1999-11-01 00:00:00
abstract:INTRODUCTION:Although the third most common aneurysm within the abdomen, after aneurysms of the aorta and iliac arteries, splenic artery aneurysms are rare, but not exceptionally. Owing to new imaging techniques, they have been discovered with increasing frequency. CASE OUTLINE:Authors present a 47-year-old woman, mul...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh1012760c
更新日期:2010-11-01 00:00:00
abstract:INTRODUCTION:Compliance with hypertension guidelines in clinical practice is generally poor, but there was no data about compliance with any guidelines in general practice in Slovenia. OBJECTIVE:Our aim was to find out whether general practitioners in Slovenia managed their hypertensive patients according to the natio...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh0704191p
更新日期:2007-03-01 00:00:00
abstract::Taking into account the important role of oestrogen and NK cells in the process of cancerogenesis, the content of receptors for steroid hormones and NK cell activity was investigated in 31 patients with breast cancer. The analysis of steroid receptors showed the usual distribution with regard to clinical stage. The va...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract::Maria Müller was one of the first female ophthalmologists in Serbia. Having researched the documents from several archives in Serbia-Belgrade, Novi Sad and Sremska Mitrovica, we were able to follow her life and work. Maria Müller was born in Budapest in 1883. From 1909 to 1919 she worked at the Budapest Hungarian Roya...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 传,历史文章,杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract::The ileal pouch-anal operation is the best procedure because it liberates the patient from ulcerative colitis i.e. from diseased mucosa of the large intestine. The ileal pouch forms a new reservoir for the storage of feces. Symptomatic pouch inflammation (pouchitis) appeared in 7-40% of the patients. The authors descr...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:1994-09-01 00:00:00
abstract:INTRODUCTION:Term breech presentation occurs in 3-4% of all deliveries. Most obstetricians are completely sure how to end delivery when the foetus is in breech presentation, by caesarean section as the only option. OBJECTIVE:The main goal of the paper was to present the method of delivery for term breech presentation ...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh1104155d
更新日期:2011-03-01 00:00:00
abstract:INTRODUCTION:The prevalence of obesity is rising to epidemic proportions at the alarming rate in both developed and underdeveloped countries around the world. Current prevalence data from individual national studies suggest that the obesity prevalence in the European countries ranges from 10% to 20% for men, and 10% to...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh0702061g
更新日期:2007-01-01 00:00:00
abstract::Lipid and lipoprotein disorders are well known risk factors for atherosclerosis and its complications. The level of atherogenic LDL-cholesterol (LDL-C) is directly related to an increased risk of occurrence and progression of ischemic heart disease. Epidemiological and clinical studies have shown that the use of stati...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章,评审
doi:10.2298/sarh1302104s
更新日期:2013-01-01 00:00:00
abstract:INTRODUCTION:In most countries, cardiovascular diseases are the leading disorders, with ischemic heart diseases being the leading cause of death. According to WHO data, every year about 17 million people die of cardiovascular diseases, which is 30% of all deaths. Ischemic heart diseases contribute from one-third to one...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh0812598r
更新日期:2008-11-01 00:00:00
abstract::Low-grade astrocytomas comprise a group of primary brain neoplasms with relatively low anaplastic potential, although through time they tend to behave more aggressively. They have a very heterogeneous natural course and clinical behavior. This report presents a natural history of a patient with low grade astrocytoma. ...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh0612537r
更新日期:2006-11-01 00:00:00
abstract:INTRODUCTION:Systemic lupus erythematosus is a multisystemic autoimmune disease characterized by various clinical manifestations, as well as unpredictable course and therapy response. Lupus nephritis is a severe manifestation of the disease, significantly influencing its prognosis. Since the pathogenesis of lupus nephr...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:2002-08-01 00:00:00
abstract::Nine patients with open fractures of the proximal humerus were treated using an external fixation device. All of them had grade III open fractures resulting from high-velocity missile and explosive injuries with massive foreign body contamination. Radial nerve injury was present in five and two multiply injured patien...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh0404092m
更新日期:2004-03-01 00:00:00
abstract::Inflammatory response in tissue results from a complex network of interactions between inflammatory cells (mast cells, eosinophils, basophils, macrophages) and resident cells belonging to the lung structure (like endothelial cells, fibroblasts, epithelial cells). Among structural cells, endothelial cells play a critic...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章,评审
doi:
更新日期:1998-03-01 00:00:00
abstract::The aim of our study was to examine the frequency of Chlamydia trachomatis infection in newborns by detecting specific antibodies, and to examine the Apgar score and the birth weight of Chlamydia trachomatis-antibody positive children. Fifty-two newborn infants were tested. High serum IgG chlamydial specific antibody ...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:1995-09-01 00:00:00
abstract::Chronic renal failure (CRF) is almost always associated with high arterial blood pressure. Adequate control of hypertension slows down the progression of the disease, Inhibitors of angiotenzin-converting enzyme (ACE inhibitors) have proved to be very efficacious in decreasing high blood pressure. The aim of this study...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh0204087t
更新日期:2002-03-01 00:00:00
abstract:INTRODUCTION:The development of effective medications makes pharmacological therapy of BPH the dominant mode of treatment today. It improves urinary symptoms and prevents disease progression while producing side effects on male sexual function. OBJECTIVE:The aim of the study is to present the effects of BPH pharmacolo...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh1506284s
更新日期:2015-05-01 00:00:00
abstract:INTRODUCTION:It has been shown that depolarization disorders, autonomic dysfunction, and systolic dysfunction of the left ventricle are associated with sudden cardiac death after myocardial infarction. OBJECTIVE:The objective of study was to examine the prognostic value of the most important predictors in the first we...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh0612482m
更新日期:2006-11-01 00:00:00
abstract:INTRODUCTION:Intramural haematoma (IMH) and penetrating aortic ulcers (PAU) are the frequent cause of acute aortic syndrome that is disclosed with a rising frequency due to the development of new diagnostic methods. Different symptoms contribute to clinical misdiagnosis, while changeable locations and unpersuasive diam...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh1106380k
更新日期:2011-05-01 00:00:00
abstract::From the historical point of view, there are three time periods when the process of modernization of Serbian society took place. First period includes the interval from the beginning of the 19th century until the end of World War I, when the Serbian country was reestablished as Serbian Knezevina (princedom) and in 188...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 历史文章,杂志文章
doi:
更新日期:2013-11-01 00:00:00
abstract::The aim of the present study was to evaluate the state of bone mass in obese individuals. Osteocalcin (OC) and parathormone (PTH) were measured (by RIA) in the sera of 137 obese, 32 premenopausal women, 65 postmenopausal women and 40 males, as well as in 28 controls, non-obese individuals. Values of OC and PTH were si...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:1994-03-01 00:00:00
abstract:INTRODUCTION:Previous studies suggested that effects of the surfactant administration in preterm intants with respiratory distress syndrome cannot be followed by lung ultrasound (L-US). OBJECTIVE:The aim of the paper is to evaluate the surfactant replacement therapy effects using a new, proposed grading system for L-U...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh1512669l
更新日期:2015-11-01 00:00:00
abstract:INTRODUCTION:Theory of multiple intelligences (MI) is considered an innovation in learning the English language because it helps students develop all eight intelligences that, on the other hand, represent ways people understand the world around them, solve problems and learn. They are: verbal/linguistic, logical/mathem...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:Prevalence of sensorineural hearing loss is 1-3 per 1,000 newborns. Transient evoked otoacoustic emission (TEOAE) and automated auditory brain stem responses (AABR) are most frequently used methods in newborn hearing screening programmes. OBJECTIVE:The aim of this study was to examine hearing function in ...
journal_title:Srpski arhiv za celokupno lekarstvo
pub_type: 杂志文章
doi:10.2298/sarh0706264b
更新日期:2007-05-01 00:00:00