[Beta-adrenergic blockers in congestive heart failure: pro et contra?].

Abstract:

:In every patient with congestive heart failure there is a secondary neurohumoral response including increase in serum noradrenaline, renin, angiotensin, aldosteron and antidiuretic hormone or arginine-vasopressin values. Plasma and urine noradrenaline levels are increased proportionally to the severity of ventricular dysfunction, but its reserve is often reduced in the myocardium as well as the density of beta receptors and sensitivity to catecholamines and inotropic responses to the stimulation of adrenergic nerves. Down-regulation of beta-adrenoceptors in the myocardium, verified by the technique of radioligands, with the reduced number of beta-adrenoceptors, is accompanied by the appearance of refractoriness and desensitization to endogenous and exogenous catecholamines. Chronic beta-blockade may improve haemodynamic and clinical function in patients with dilated cardiomyopathy or congestive heart failure, because beta-blockers have potentially beneficial actions: protection of the myocardium from damage by chronic excessive catecholamine stimulation, restoration toward normal of the down-regulated membrane beta-receptor density often seen in heart failure, reduction in the risk of potentially lethal ventricular arrhythmias and beneficial effects on substrate utilization. Our results of investigation in 20 patients with congestive heart failure treated with beta-blockers short and long-term (average 22 months) gave substantial increases in ejection cardiac index and improved functional class and also improved working capacity.

journal_name

Srp Arh Celok Lek

authors

Trifunović SL,Pavlović K

subject

Has Abstract

pub_date

1992-06-01 00:00:00

pages

44-50

eissn

0370-8179

issn

2406-0895

journal_volume

120 Suppl 4

pub_type

杂志文章
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    authors: Grković S,Jesić M,Jesić M,Maglajlić S

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  • [Spinal localization of Paget disease--case report].

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    doi:10.2298/sarh0808419v

    authors: Vukasinović Z,Slavković N,Spasovski D,Slavković S

    更新日期:2008-07-01 00:00:00

  • [Early risk predictors of sudden cardiac death after myocardial infarction: results of follow up of 881 patients].

    abstract:INTRODUCTION:It has been shown that depolarization disorders, autonomic dysfunction, and systolic dysfunction of the left ventricle are associated with sudden cardiac death after myocardial infarction. OBJECTIVE:The objective of study was to examine the prognostic value of the most important predictors in the first we...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

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    authors: Milovanović B,Krotin M,Vuković D,Bisenić V,Mirjanić T,Nikolić S

    更新日期:2006-11-01 00:00:00

  • [Updated criteria for diagnosis and risk stratification in patients with multiple myeloma].

    abstract::Search and disclosure of most adequate diagnostic criteria and prognostic indicators of disease represents one of the most difficult tasks in the understanding of any disease, which creates the way toward a more successful treatment and longer survival. The recent advances in research techniques that have helped refin...

    journal_title:Srpski arhiv za celokupno lekarstvo

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    authors: Djurdjević P,Andjelković N,Bila J

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  • [Analysis of regulatory-ethical framework of clinical trials].

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    authors: Georgiev AM,Krajnović D,Milovanović S,Ignjatović S,Djurić D,Marinković V

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  • [The role of endothelial cells in allergic inflammation reactions].

    abstract::Inflammatory response in tissue results from a complex network of interactions between inflammatory cells (mast cells, eosinophils, basophils, macrophages) and resident cells belonging to the lung structure (like endothelial cells, fibroblasts, epithelial cells). Among structural cells, endothelial cells play a critic...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章,评审

    doi:

    authors: Stefanović Lj,Bogić M,Balaban J,Mitrović O,Stosović R,Andrejević S

    更新日期:1998-03-01 00:00:00

  • [Principles of phoniatric voice rehabilitation I: classification of voice disorders].

    abstract::There is a variety of terms related to the classification of voice disorders still in use. The basic characteristics are discussed. Classification according to Perello, modified by the author, is recommended. On the basis of this classification, the "basic diagnosis" is suggested, with all necessary diagnostic procedu...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章,评审

    doi:

    authors: Milutinović Z

    更新日期:1995-05-01 00:00:00

  • [Ewing's sarcoma in children: prognosis in relation to the method of treatment].

    abstract::Ewing's tumor of bone is the second primary malignant bone tumor. Localized lesion is found in nearly 80% of cases and metastatic lesions are present in 20% at the time of diagnosis. Treatment protocols were analyzed, prognostic parameters were evaluated, and overall survival as well as survival until relapse of disea...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:10.2298/sarh0610420s

    authors: Stevanović V,Vukasinović Z,Spasovski D

    更新日期:2006-09-01 00:00:00

  • [Record of successful sertraline treatment of a pathological gambler].

    abstract::This is a case report of 26-year old, advanced university student of the Faculty of Science, Department of Mathematics, single. He has never been a psychiatric patient, but being unable to suppress the gambling impulse, he presented for treatment, on his own initiative, to the outpatient department. Patient met the cr...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:10.2298/sarh0602060m

    authors: Milovanović S,Leposavić L,Barisić J,Nikolić-Balkoski G

    更新日期:2006-01-01 00:00:00

  • [Successfull extirpation of femoral pseudotumour in a patient with severe haemophilia A and an inhibitor to factor VIII].

    abstract::The article deals with a successfull extirpation of femoral pseudotumour in a 53-year-old patient with severe haemophilia A (F VIII: C less than 1%) and an inhibitor to factor VIII. Such case is the first one reported in Yugoslavia. A combination of ultrasonography, computed axial tomography, angiography and Tc-99m la...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:

    authors: Marisavljević D,Glisić M,Elezović I,Popović A,Rolović Z

    更新日期:1991-11-01 00:00:00

  • Seroprevalence study in Vojvodina (Serbia) following 2009 pandemic influenza A(H1N1)V.

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    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:

    authors: Petrović V,Reguljev Z,Nedeljković J,Ristić M

    更新日期:2012-11-01 00:00:00

  • [Effect of vitamin E on erythrocyte enzymes and total antioxidant status in diabetic patients with ischemic heart disease].

    abstract::Lipid peroxidation is thought to be one of the major factors involved in atherogenesis. There is an increasing evidence is increasing that oxidation of LDL cholesterol may be instrumental in atherogenesis. Diabetics are known to be at increased risk of cardiovascular diseases, a phenomenon which has previously been li...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 临床试验,杂志文章

    doi:

    authors: Knezević V,Mujović VM,Milosević A

    更新日期:2000-07-01 00:00:00

  • Heterotopic pregnancy after in vitro fertilization and embryo transfer: a case report.

    abstract:INTRODUCTION:Heterotopic pregnancy is a life-threatening complication of pregnancy defined as coexistent intrauterine and ectopic gestation. Its diagnosis is frequently overlooked and delayed. CASE OUTLINE:A 28-year-old woman experienced acute abdominal pain in pregnancy achieved by in vitro fertilization. Since all p...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:

    authors: Sparić R,Buzadzić S,Argirović R,Bratić D,Plećas D

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  • [Wound infection after carotid artery endarterectomy caused by methicillin-resistant Staphylococcus aureus: case report].

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    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:10.2298/sarh1104225p

    authors: Popov P,Tanasković S,Matić P,Babić S,Nenezić D,Jovanović P,Ilijevski N,Vucurević G

    更新日期:2011-03-01 00:00:00

  • [Volunteer blood donors--relation between gender and motivation].

    abstract::The study included 1,825 persons, aged from 18 to 65 years. A representative sample was formed of 1,325 persons who donated blood for the first time, and of 500 persons who donated blood five or more times till the moment of investigation. Among blood donors in the Republic of Serbia, regardless the number of blood do...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:

    authors: Andjelić D

    更新日期:1991-07-01 00:00:00

  • Lesion of the femoral nerve caused by a hydatid cyst of the right psoas muscle.

    abstract:INTRODUCTION:Hydatidosis is a human disease caused by the larval form of Echinococcus granulosus. All organs in the human body may be affected by hydatid disease, but excluding liver and lungs, all other organs are considered as uncommon locations. Hydatid disease located in the psoas muscle is uncommon. CASE OUTLINE:...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:10.2298/sarh1008502b

    authors: Bilanović D,Zdravković D,Randjelović T,Tosković B,Gacić J

    更新日期:2010-07-01 00:00:00

  • [Applicability of visual-analogue scale in patients with orofacial ain].

    abstract:INTRODUCTION:Orofacial pain occurs in various disorders of the orofacial region. OBJECTIVE:The aim of this study was to examine applicability of the visual-analogue scale (VAS) in patients with orofacial pain (model of acute and chronic pain). METHODS:The study involved 60 patients, aged 18-70 years. The first group ...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:

    authors: Lončar J,Panić Z,Stojšin I,Savović S,Petrović B

    更新日期:2013-07-01 00:00:00

  • [Inhibition of angiogenesis in the cornea with amiloride].

    abstract:INTRODUCTION:For its transparency, avascularity and possibility of measurement of the new vessels ingrowth, cornea is a frequent model for angiogenesis research. New vessels are made in several phases: after the action of the stimulus, there is a localised fragmentation of the basal membrane and the extracellular matri...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:

    authors: Ignjatović Z,Nikolić Lj

    更新日期:1996-05-01 00:00:00

  • [T lymphocytes in allergic inflammation].

    abstract::T lymphocytes are the crucial cells in immunopathogenesis of allergic diseases since they regulate the occurrence of allergic sensitisation, synthesis of immunoglobulin E and allergic inflammation. The importance of lymphocyte T is reflected on the fact that after activation by a specific antigen they are able to prod...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章,评审

    doi:

    authors: Tomić-Spirić V,Bogić M,Janković S,Rasković S,Djurić V,Sojić-Rajcić J

    更新日期:1998-07-01 00:00:00

  • [Infected tibial nonunions--treatment by the Ilizarov method: multicentric study].

    abstract:INTRODUCTION:Associated bone tissue defect and infection, commonly result in non-healing, i.e., by the development of infected tibial nonunion. OBJECTIVE:The aim of the paper was to present experiences acquired in the treatment of this problem by the application of the Ilizarov method. METHODS:The analyses enrolled 1...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章,多中心研究

    doi:10.2298/sarh1202065v

    authors: Vukašinović Z,Spasovski D,Vučetić Č,Jovanović V,Šešlija I,Živković Z

    更新日期:2012-01-01 00:00:00

  • [Outcomes of surgery for total anomalous pulmonary venous drainage].

    abstract:INTRODUCTION:Total anomalous pulmonary venous connection (TAPVC) is a rare congenital heart disease and in some variants represents the only true surgical emergency in congenital heart surgery. Basic anatomical characteristic of this anomaly is an abnormal connection of pulmonary veins with systemic venous circulation....

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:10.2298/sarh1404164m

    authors: Milovanović V,Mimić B,Vulićević I,Divac I,Parezanović V,Ilisić T,Djukić M,Jovanović I,Ilić S

    更新日期:2014-03-01 00:00:00

  • [The value of neuroendocrine markers for response to therapy and survival in patients with advanced non-small cell lung cancer].

    abstract:INTRODUCTION:Non-small cell lung cancer (NSCLC) accounts for about 70-80% of all lung cancers. In comparison with small cell lung cancer, NSCLC has relatively low therapy response. Discovery of neuroendocrine markers within the NSCLC group (10-30%) has initiated the issue of their importance in the therapy and prognosi...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:10.2298/sarh1002037p

    authors: Petrović M,Ilić N,Baskić D

    更新日期:2010-01-01 00:00:00

  • [Gilbert's syndrome in children--our experience].

    abstract:INTRODUCTION:Gilbert's syndrome represents the most frequent hereditary disorder of bilirubin metabolism. It occurs in 2-7% of subjects in general population, and is manifested by mild unconjugated hyperbilirubinaemia of benign nature. OBJECTIVE:The study was conducted in order to analyse our experience related to the...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:10.2298/sarh0706317r

    authors: Radlović N,Leković Z,Mladenović M,Ristić D,Radlović V,Lekić V,Vuletić B,Djurdjević J,Gajić M

    更新日期:2007-05-01 00:00:00

  • Mesenchymal stem cells isolated from peripheral blood and umbilical cord Wharton's jelly.

    abstract:INTRODUCTION:Mesenchymal stem cells (MSCs) are a promising tool for regenerative medicine, but due to the heterogeneity of their populations, different sources and isolation techniques, the characteristics defining MSCs are inconsistent. OBJECTIVE:The aim of this study was to compare the characteristics of MSCs derive...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:10.2298/sarh1304178t

    authors: Trivanović D,Kocić J,Mojsilović S,Krstić A,Ilić V,Djordjević IO,Santibanez JF,Jovcić G,Terzić M,Bugarski D

    更新日期:2013-03-01 00:00:00

  • [Meningitis in neonates].

    abstract::The article deals with retrospective analysis of a seven-year autopsic material from the Institute of Pathologic Anatomy in Pristina. The aim of this analysis was to define the frequency, morphology and predisposing factors of neonatal meningitis. A good knowledge of morphology and predisposing factors in necessary in...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:

    authors: Mitić N

    更新日期:1991-03-01 00:00:00

  • Giant Vertebrobasilar Fusiform Aneurysm as a Cerebellopontine Angle Mass.

    abstract:INTRODUCTION:According to the literature, a fusiform aneurysm located in the cerebellopontine angle (CPA) is an extremely rare condition. CASE OUTLINE:We report a case of a 59-year-old patient with initial dizziness and left-sided sensorineural hearing loss that had gradually developed over six months. Vertebrobasilar...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:10.2298/sarh1512731z

    authors: Živković NZ,Marković M,Aleksić V,Jovanović MB

    更新日期:2015-11-01 00:00:00

  • [Relationship between degree of dyspnoea and health-related quality of life in patients with chronic obstructive pulmonary disease].

    abstract:INTRODUCTION:Dyspnoea is a characteristic symptom of chronic obstructive pulmonary disease (COPD), which impairs everyday functioning of patients. OBJECTIVE:The aim of our study was to evaluate the relationship between the degree of dyspnoea of COPD patients and their health-related quality of life. METHOD:We measure...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:10.2298/sarh0710547g

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    更新日期:2007-09-01 00:00:00

  • [Chlamydia urethritis in nephrologic practice].

    abstract::Chlamydia trachomatis is an ubiquitous bacterium, strictly intracellular organism. The D-K serovars urethritis, cervicitis, endometritis, salpingitis, periappendicitis and perihepatitis, in women, urethritis, prostatitis, epididymitis and Reiter's syndrome in 1-2% of cases in men. Sterility is the most serious complic...

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    pub_type: 杂志文章

    doi:

    authors: Stanojcić A,Perić J,Radmilović A

    更新日期:1996-01-01 00:00:00

  • [St. Sava--the founder of hospital health service, social security (benefit) and medical education program in Serbia].

    abstract::The first written serbian medical records could be found in the Middle Ages (XIIIth century) when the serbian state was very well organized. St. Save was the son of Grand-Prince Stefan Nemanja (1171-1196), founder of the Serbian independent state and of a powerful dynasty that ruled Serbia for two centuries. At that t...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 传,历史文章,杂志文章

    doi:

    authors: Pavlović B,Dragović S

    更新日期:1994-03-01 00:00:00

  • [The effect of preliminary administration of dimethylsulfoxide on the development of experimental myocardial necrosis in rats treated with isoprenaline].

    abstract::It has been suggested that in the genesis of isoprenaline-induced myocardial necrosis in rats, along with the intracellular calcium homeostasis and energy production breakdown, the mechanism of cytotoxic oxygen free radical generation is also included. The effects of dimethylsulphoxide, a hydroxyl radical scavenger, o...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:

    authors: Ljubuncić P,Mujić F,Stojiljković MP,Vinterhalter-Jadrić M

    更新日期:1991-09-01 00:00:00