Lymphoblastic lymphomas in children – A single-center experience from Serbia.

Abstract:

Introduction:Intensive treatment protocols used for non-Hodgkin lymphoma in children lead to eventfree survival rates ranging from 80% to 90%. However, the results are less successful in developing countries. Lymphoblastic lymphoma (LBL) is the second most frequent type of lymphoma in children, contributing with about one third to all non-Hodgkin lymphoma in childhood. Objective:The aim of the study was to evaluate the results of LBL treatment in University Children’s Hospital (UCH), Belgrade. Methods:A retrospective analysis of patient records at UCH from 1997 to 2015 was carried out in patients aged 0–18 years, in whom the diagnosis of LBL had been established. Twenty-two children were included in the analysis. Results:Mean age at diagnosis was 10 years, with preponderance of male patients. All patients were treated according to Berlin-Frankfurt-Münster-based chemotherapy protocols. With median follow-up of 91.5 months, five-year probability of event-free survival was 79.5% for all patients, while overall survival was 81.8%. Conclusion:Our results, although slightly inferior to those of leading international groups, reflect a good treatment outcome in our patients.

journal_name

Srp Arh Celok Lek

authors

Lazić J,Janić D,Krstovski N,Rodić P,Milošević G,Janković S,Brašanac D,Dokmanović L

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

413-7

issue

7-8

eissn

0370-8179

issn

2406-0895

journal_volume

144

pub_type

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