Abstract：
INTRODUCTION:Balkan endemic nephropathy (BEN) patients maintained with hemodialysis have more severe anemia than patients with other kidney diseases. OBJECTIVE:The aim of the study was to compare the improvement of anemia in BEN patients and those with other kidney diseases during treatment with human recombinant erythropoietin (rHuEpo). METHODS:The study involved 240 patients on regular hemodialysis for more than one year. Out of them 146 had BEN and 94 other kidney diseases (21 glomerulonephritis, 20 hypertension, 18 diabetes, 10 policystic kidney disease, 5 obstructive nephropathy, 18 other diseases). Treatment with rHuEpo was carried out according to European guidelines for the management of anemia. RESULTS:Patients with BEN were older and were less frequently treated with ACEi than patients with other kidney diseases. At the onset of the study mean hemoglobin level (109.6 +/- 22.3 vs. 112.7 +/- 11.3 g/l) was significantly lower, but serum ferritin level and rHuEpo dose (65.4 +/- 22.3 vs. 57.5 +/- 22.5 U/kg/week) were significantly higher in BEN patients than in others. In prospective four months study these differences in hemoglobin levels and rHuEpo doses maintained.The rate of anemia improvement was examined in 15 BEN patients and 10 patients with other kidney diseases at the beginning of rHuEpo treatment. No difference in the rate of anemia improvement was found between the two groups but higher rHuEpo doses were used in BEN patients. CONCLUSION:Patients with BEN on regular hemodialysis had more severe anemia and required higher rHuEpo doses for maintaining target hemoglobin level.
journal_name
Srp Arh Celok Lekjournal_title
Srpski arhiv za celokupno lekarstvoauthors
Lukić L,Mitrović D,Kovačević S,Stanišić M,Pelemiš Sdoi
10.2298/sarh1208456lsubject
Has Abstractpub_date
2012-07-01 00:00:00pages
456-61issue
7-8eissn
0370-8179issn
2406-0895journal_volume
140pub_type
杂志文章abstract：:One of the most frequent causes of deterioration of chronic obstructive lung diseases is the infection. The existence of microorganisms resistant to antibiotics is becoming an increasingly serious therapeutical problem. Kinolones have a wider spectrum of action than the majority of other antibiotics, with strong effec...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：:Blood pressure measurements obtained in a physicians office may not reflect the patients blood pressure during the whole day. Ambulatory blood pressure monitoring provides information about blood pressure during normal daily activities and night sleep. Further, the results of ambulatory blood pressure monitoring are i...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1997-05-01 00:00:00
abstract：:During the space flight the cosmonaut is exposed to many stressogenic factors. The science is especially interested in microgravitation as an environmental element affecting the life of the crew in a cosmic vehicle, which is in contrast with human physiology in terrestrial conditions. The space medicine is interested ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：1995-07-01 00:00:00
abstract：INTRODUCTION:Thirty to 50% of patients with chronic hepatitis C (CHC) have one or more extrahepatic manifestations (EHMs) of hepatitis C virus (HCV) infection. OBJECTIVE:The aim of this study was to evaluate the frequency of EHMs and to investigate the efficacy of pegylated interferon (Peg-IFN)-alpha-2a plus ribavirin...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1306320f
更新日期：2013-05-01 00:00:00
abstract：INTRODUCTION:Campylobacter jejuni and Campylobacter coli represent one of the main causes of bacterial diarrhoea in humans. Although the disease is usually mild and self-limiting, severe chronic sequelae may occur, such as reactive arthritis, Guillain-Barré and Miller Fisher syndromes. Serotyping is used as an epidemio...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1012721m
更新日期：2010-11-01 00:00:00
abstract：:In the past two decades a huge progress was achieved in the treatment of malignant diseases in children. The cyclical chemotherapy combined with surgery and radiotherapy gave very good results. However, the contribution of chemotherapy to paediatric neuro-oncology was not as great is it was to other branches of paedia...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：1989-11-01 00:00:00
abstract：INTRODUCTION:Autoimmune cholangitis or immunoglobulin G4-associated cholangitis (IAC) has been recently regarded as a new clinical and histopathological entity and is a part of a complex autoimmune disorder--IgG4-related systemic disease (ISD). ISD is an autoimmune disease with multi-organic involvement, characterized ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1506337i
更新日期：2015-05-01 00:00:00
abstract：INTRODUCTION:Subarachnoidal hemorrhage (SAH) is the fourth most common intracranial cause of death. Approximately 50 to 85 percent of non-traumatic SAH is caused by rupture of congenital berry aneurysm. Symptoms of rupture are typically sudden and without any heralds. In most SAH cases, the vasospasm following the rupt...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0408236n
更新日期：2004-07-01 00:00:00
abstract：:It is widely accepted that alcohol metabolism passes through different mechanisms: alcohol dehydrogenase (ADH) activity in stomach epithelial cells, activity of ADH in the liver, microsomal-ethanol-oxydizing system (MEOS), hepatocyte catalase activity, and nonoxydizing metabolic pathway (production of fatty acid ethyl...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：1996-09-01 00:00:00
abstract：:In recent years, the development of new surgical techniques in uterus myoma treatment have reduced operative trauma significantly. Our objective was to present operative technique--vaginal myomectomy, making a prospective clinical study where we have evaluated the operative and postoperative period after intentive dia...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0402018m
更新日期：2004-01-01 00:00:00
abstract：:Professional management of paediatric diabetology, according to consensus guidelines, involves the screening of microvascular complications at puberty. The subclinical form of peripheral neural dysfunction in diabetic teenagers is reported with a frequency of 50-88%, by different authors. The purpose of this study was...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0508358s
更新日期：2005-07-01 00:00:00
abstract：INTRODUCTION:According to the literature, a fusiform aneurysm located in the cerebellopontine angle (CPA) is an extremely rare condition. CASE OUTLINE:We report a case of a 59-year-old patient with initial dizziness and left-sided sensorineural hearing loss that had gradually developed over six months. Vertebrobasilar...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1512731z
更新日期：2015-11-01 00:00:00
abstract：:The aim of this work was to estimate influence of activated immune response on hematopoiesis in vitro, using the experimental model of BCG immunized BALB/c mice and in patients with chronic immunoactivation: long-lasting infections, autoimmunity or malignancy. We correlated changes in long term bone marrow cultures (D...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:Detrusor tunnelling is an extravesical surgical procedure of ureteral reimplantation. It is surely the least traumatic method of surgical correction of vesico-ureteral reflux because antireflux mechanism is achieved with minimal detrusor muscle dissection. This procedure simplifies implantation of dilated ureters, dou...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:Inflammatory response in tissue results from a complex network of interactions between inflammatory cells (mast cells, eosinophils, basophils, macrophages) and resident cells belonging to the lung structure (like endothelial cells, fibroblasts, epithelial cells). Among structural cells, endothelial cells play a critic...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：
更新日期：1998-03-01 00:00:00
abstract：:The first written serbian medical records could be found in the Middle Ages (XIIIth century) when the serbian state was very well organized. St. Save was the son of Grand-Prince Stefan Nemanja (1171-1196), founder of the Serbian independent state and of a powerful dynasty that ruled Serbia for two centuries. At that t...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 传,历史文章,杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：INTRODUCTION:Because apical periodontitis is recognizably an infectious disease, elimination or reduction of intracanal bacteria is of utmost importance for optimum treatment outcome. OBJECTIVE:The prevalence of Enterococcus faecalis and Porphyromonas gingivalis in infected root canals was studied Also, the effect of ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1410535s
更新日期：2014-09-01 00:00:00
abstract：:Clinical manifestation of chronic rhinitis is due to local release of mediators from inflammatory cells. Eosinophil leukocytes are important in pathogenesis of nasal hypersensitivity as well as nasal hyperreactivity [1, 2]. The aim of the study was to follow-up the effect of local corticosteroid treatment on a number ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 临床试验,杂志文章
doi：10.2298/sarh0208243u
更新日期：2002-07-01 00:00:00
abstract：INTRODUCTION:Although the third most common aneurysm within the abdomen, after aneurysms of the aorta and iliac arteries, splenic artery aneurysms are rare, but not exceptionally. Owing to new imaging techniques, they have been discovered with increasing frequency. CASE OUTLINE:Authors present a 47-year-old woman, mul...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1012760c
更新日期：2010-11-01 00:00:00
abstract：:During the last five years at our Department renal biopsy was carried out in 41 patients with systemic lupus erythematosus. On the basis of the pathologic findings glomerular changes were classified as follows: minimal in 5 patients; mesangial proliferative glomerulonephritis in 11; focal and segmental proliferative g...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：INTRODUCTION:Predictable endodontic treatment depends on the dentist's knowledge about root canal morphology and its possible anatomic variations. The majority of mandibular canines have one root and root canal, but 15% may have two canals and a smaller number may have two distinct roots. The following clinical reports...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1410592s
更新日期：2014-09-01 00:00:00
abstract：:Hernia repair is one of the most common surgical procedures performed in the United States, with 700,000 operations performed each year. Improvements in surgical technique, together with the development of new prosthetic materials and a better understanding of how to use them, have significantly improved outcomes for ...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：10.2298/sarh0302082m
更新日期：2003-01-01 00:00:00
abstract：INTRODUCTION:Retinopathy of prematurity (ROP) is a multifactorial disease that occurs most frequently in very small and very sick preterm infants, and it has been identified as the major cause of childhood blindness. OBJECTIVE:The aim of this study was to evaluate ROP incidence and risk factors associated with varying...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：2011-07-01 00:00:00
abstract：INTRODUCTION:Ameloblastic fibroma (AF) is a rare benign odontogenic tumor that usually occurs in the fi two decades of life. It affects adolescents and young adults and is found in the mandible and with a high frequency in the posterior region of this segment. There are rare case reports with a long-term follow-up. CA...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1504190a
更新日期：2015-03-01 00:00:00
abstract：INTRODUCTION:An algorithm to study hand movements in patients with Parkinson's disease (PD) who experience temporary, involuntary inability to move a hand have been developed. In literature, this rather engimatic phenomenon has been described in gait, speech, handwriting and tapping, and noted as motor blocks (MB) or f...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0212376p
更新日期：2002-11-01 00:00:00
abstract：:Coagulative disorders may result from a breakdown in the balance between coagulation and fibrinolysis. It is important to assess relative physiological states of coagulation and fibrinolysis related to operation. An ideal outcome in orthopaedic surgical procedures is the achievement of adequate haemostasis without exc...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章,评审
doi：10.2298/sarh0910567d
更新日期：2009-09-01 00:00:00
abstract：:Second trimester pregnancy, of 16-24 weeks' gestation, was interrupt ed in 33 women by means of an instillation of 150-200 ml of a 25% solution of sodium chloride. 14 abortions were for psychiatric reasons and 16 for infectious problems. Full abortion occurred in all patients; time required was 32 hours and 8 minut...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1974-03-01 00:00:00
abstract：:The objective of the study was to test the possibility of using the fixed value (12-13) of the Rating of Perceived scale (RPE scale), as a valid method for determination of ventilatory threshold (VT). The sample of the subjects included 32 physically active males (age: 22.3; TV: 180.5; TM: 75.5 kg; VO2max: 57.1 mL/kg/...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh0412409s
更新日期：2004-11-01 00:00:00
abstract：:Nosocomial infections (NI) are infections acquired in hospitals. The aim of this paper is to describe the organization of NI control program in France. The organization of this program started in 1988 by the formation of the Infection Control Committees in hospitals. Their role has been to organize the surveillance of...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：
更新日期：1999-11-01 00:00:00
abstract：INTRODUCTION:Diabetes mellitus as a complex metabolic disease influences functioning of numerous organs. Chronic periodontitis is one of frequent diabetic complications. OBJECTIVE:The aim of this study was to compare the clinical effects of non-surgical periodontal therapy between diabetes mellitus type 2 patients (DM...
journal_title：Srpski arhiv za celokupno lekarstvo
pub_type： 杂志文章
doi：10.2298/sarh1312738m
更新日期：2013-11-01 00:00:00
