[Serum antithyroid antibodies in patients with pernicious anemia].

Abstract:

:We investigated the incidence of thyroid auto-antibodies and their relationship to antigastric antibodies in 20 euthyroid patients with pernicious anaemia. To evaluate possible thyroid dysfunction we also measured total level of thyroid hormones (TT3 and TT4) and TSH in our patients. Histologic evidence of autoimmune atrophic gastritis and intestinal metaplasia was obtained in 15 patients. We found that it was surprisingly high incidence of thyroid auto-antibodies in patients with pernicious anaemia, particularly in the group with intestinal metaplasia (antithyreoglobulin antibodies 71% and antimicrosomal antibodies 100%). The incidence of antigastric antibodies in these patients was similar to that of those with significant antithyroid antibodies (16/18). Total triiodo thyronine and TSH were significantly higher in the patients with pernicious anaemia than in the control group (p less than 0.05), in the normal range. The results of our study suggest that this upset in immunological physiology is due to a more generalized defect in immune tolerance.

journal_name

Srp Arh Celok Lek

authors

Kostić N,Jelić S,Han R,Ristić S,Bozanić M

subject

Has Abstract

pub_date

1990-07-01 00:00:00

pages

303-6

issue

7-8

eissn

0370-8179

issn

2406-0895

journal_volume

118

pub_type

杂志文章
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    abstract::The authors present their views of the most frequent difficulties and possible oversights in the diagnosis of chronic secretory otitis on the basis of the treatment of 950 children in all departments. An insidious, subclinical and long-lasting course of chronic secretory otitis, the age of this population and very oft...

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    authors: Lucić M,Mandilović M,Vukoje N,Haralampijev K

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  • [Fungal and tuberculous peritonitis in patients on peritoneal dialysis: characteristics, therapy and outcome].

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    doi:

    authors: Jovanović DB

    更新日期:2005-03-01 00:00:00

  • [Colonic sphincters--Hirsch's sphincter].

    abstract::Anatomic and physiological sphincters of the colon are localized narrowness of the colon with adequate name. These sphincters appear due to the thickening of longitudinal and circular muscle fibers in the wall of colon or due to the reflex irritation of the autonomous nervous system which innervates the colon. If they...

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    pub_type: 杂志文章

    doi:

    authors: Saranović Dj,Ilić N,Stafanović Z,Kasiković M

    更新日期:1991-05-01 00:00:00

  • [Immune complexes in diabetes mellitus].

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    pub_type: 杂志文章

    doi:

    authors: Kocić R,Radenković S,Milenović M,Mijailović M,Koraćević G,Zivić S,Pesić M,Kosić G

    更新日期:1994-01-01 00:00:00

  • [Sensitivity of criteria for MRI interpretation in patients with multiple sclerosis].

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    doi:

    authors: Perić V,Drulović J,Stojsavljević N,Sokić D,Dragutinović G,Lević Z

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  • [Analysis of regulatory-ethical framework of clinical trials].

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    pub_type: 杂志文章

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    authors: Georgiev AM,Krajnović D,Milovanović S,Ignjatović S,Djurić D,Marinković V

    更新日期:2013-09-01 00:00:00

  • [Treatment of missed Monteggia lesion in children--case report].

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    pub_type: 杂志文章

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    authors: Vukasinović Z,Jovanović V,Mitović D,Slavković N

    更新日期:2011-01-01 00:00:00

  • Foreign scientists on the contribution of Serbian physician and scientist Dr. Lazar K. Lazarević to medical science.

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    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 历史文章,杂志文章

    doi:10.2298/sarh1602111d

    authors: Draca S

    更新日期:2016-01-01 00:00:00

  • Non-Hodgkin lymphomas in childhood: how to move on?

    abstract::Non-Hodgkin lymphomas of childhood represent a diverse group of neoplasms with different clinical, pathological, immunophenotypical and genetic features. A vast majority of childhood non-Hodgkin lymphomas could be classified into one of the three major histological subgroups: mature B-cell neoplasms, lymphoblastic lym...

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    pub_type: 杂志文章,评审

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    authors: Dokmanović L,Rodić P,Krstovski N,Lazić J,Dragana J

    更新日期:2014-07-01 00:00:00

  • [Lupus nephritis--clinical and morfological correlation].

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    pub_type: 杂志文章

    doi:

    authors: Banković N,Blagojević R,Jovanović D,Sindjić M,Pavlović S,Stojković D,Djukanović Lj

    更新日期:1994-07-01 00:00:00

  • [Anaplastic type of Wilms' tumour].

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    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:

    authors: Vujanić GM,Aleksandrović S

    更新日期:1990-09-01 00:00:00

  • Family planning among women in urban and rural areas in Serbia.

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    pub_type: 杂志文章

    doi:10.2298/sarh1312794a

    authors: Antić L,Djikanović B,Vuković D

    更新日期:2013-11-01 00:00:00

  • [Risk factors and health condition of workers in school environment].

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    pub_type: 杂志文章

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    authors: Nikolovski D,Sarić-Tanasković M

    更新日期:2006-10-01 00:00:00

  • [Recombinant activated factor VII and intraoperative use of cell saver in neurosurgical treatment of arteriovenous malformation].

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    pub_type: 杂志文章,收录出版

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    更新日期:2008-09-01 00:00:00

  • [Localised adenomyomatosis of the gall bladder].

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    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:

    authors: Colović R,Perisić-Savić M,Matić S,Kalezić V,Tatić S

    更新日期:1994-11-01 00:00:00

  • [Congenital nephrotic syndrome].

    abstract:INTRODUCTION:Congenital nephrotic syndrome is usually presented with heavy proteinuria, hypoproteinaemia, oedema and hyperlipidaemia in a child from its birth until the age of 3 months. Aetiology of the disease is mutation in the relevant gene or it develops secondary to various infections. The most common form of cong...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:10.2298/sarh08s4307s

    authors: Stajić N,Putnik J,Paripović A,Djurić S,Bogdanović R

    更新日期:2008-12-01 00:00:00

  • [Response to histamine in the skin prick test in children].

    abstract::Allergen skin reactivity to histamine assessed by Prick testing was studied in 183 children with different allergic symptoms, aged from 4 months to 15 years. No significant difference was noted in male children versus female in different parts of the arm (antecubital fossa of the left arm, wrist of both arms) and in d...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:

    authors: Kos R,Nestorović B,Maticki D,Janić D

    更新日期:1990-05-01 00:00:00

  • Heterotopic pregnancy after in vitro fertilization and embryo transfer: a case report.

    abstract:INTRODUCTION:Heterotopic pregnancy is a life-threatening complication of pregnancy defined as coexistent intrauterine and ectopic gestation. Its diagnosis is frequently overlooked and delayed. CASE OUTLINE:A 28-year-old woman experienced acute abdominal pain in pregnancy achieved by in vitro fertilization. Since all p...

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    pub_type: 杂志文章

    doi:

    authors: Sparić R,Buzadzić S,Argirović R,Bratić D,Plećas D

    更新日期:2012-07-01 00:00:00

  • [Current diagnosis of classic mastitis carcinomatosa].

    abstract::Mastitis carcinomatosa (inflammatory carcinoma) is a very rare form of breast cancer, with a rapid progress, generalisation and dissemination into the vital organs, and lethal issue. Inflammatory carcinoma of the breast (ICB) accounts for 1 to 4 per cent of all breast carcinomas. Only 3 to 6 per cent of patients survi...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章,评审

    doi:

    authors: Borojević N,Trbojević P,Zamurović J

    更新日期:1990-03-01 00:00:00

  • [Infected tibial nonunions--treatment by the Ilizarov method: multicentric study].

    abstract:INTRODUCTION:Associated bone tissue defect and infection, commonly result in non-healing, i.e., by the development of infected tibial nonunion. OBJECTIVE:The aim of the paper was to present experiences acquired in the treatment of this problem by the application of the Ilizarov method. METHODS:The analyses enrolled 1...

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    pub_type: 杂志文章,多中心研究

    doi:10.2298/sarh1202065v

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    更新日期:2012-01-01 00:00:00

  • [Biologic effects and possible therapeutic use of the granulocyte-macrophage colony-stimulating factor. Modern treatment of leukopenia].

    abstract::This review is a brief overview of recent advances in biology as well as in potential clinical application of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF). Biologically active rhGM-CSF is a recombinant human protein expressed in Escherichia coli. GM-CSF is produced by nontransformed (T...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章,评审

    doi:

    authors: Jovanović-Mićić D,Beleslin DB,Bosnjak S

    更新日期:1993-08-01 00:00:00

  • Giant Vertebrobasilar Fusiform Aneurysm as a Cerebellopontine Angle Mass.

    abstract:INTRODUCTION:According to the literature, a fusiform aneurysm located in the cerebellopontine angle (CPA) is an extremely rare condition. CASE OUTLINE:We report a case of a 59-year-old patient with initial dizziness and left-sided sensorineural hearing loss that had gradually developed over six months. Vertebrobasilar...

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    pub_type: 杂志文章

    doi:10.2298/sarh1512731z

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    更新日期:2015-11-01 00:00:00

  • [Determination of ventilatory threshold based on subjective rating of perceived exertion].

    abstract::The objective of the study was to test the possibility of using the fixed value (12-13) of the Rating of Perceived scale (RPE scale), as a valid method for determination of ventilatory threshold (VT). The sample of the subjects included 32 physically active males (age: 22.3; TV: 180.5; TM: 75.5 kg; VO2max: 57.1 mL/kg/...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

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    authors: Stojiljković S,Nesić D,Mazić S,Popović D,Mitrović D,Mitić D

    更新日期:2004-11-01 00:00:00

  • [Therapeutic use of glucocorticoids and immunosuppressive agents].

    abstract::Pharmacotherapy of autoimmune thyroid disease (AITD) is complex. Apart from the replacement hormone therapy, antithyroid agents, beta adrenoceptor blockers and other drugs, in regard to the present symptoms, it also includes the administration of glucocorticoids and immunosuppressive agents. Physiological actions of g...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章,评审

    doi:10.2298/sarh05s1067g

    authors: Grbović L,Radenković M

    更新日期:2005-10-01 00:00:00

  • [Clinical importance of tympanometry in the diagnosis of chronic secretory otitis].

    abstract::Secretory otitis media is defined as a fluid in the middle ear without signs or symptoms of infection. As the aetiology and pathogenesis of the disease are unknown, and as it affects children aged from 3 to 12 years, treatment procedures proposed for management of secretory otitis media, are not uniform. Some authors ...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:

    authors: Spremo S,Markić Z,Kurbalija

    更新日期:1998-07-01 00:00:00

  • [Pelvic inflammatory disease: contemporary diagnostic and therapeutic approach].

    abstract::Pelvic inflammatory disease (PID) is polymicrobial infection in women characterized by inflammation of the upper genital tract, including endometritis, salpingitis, pelvic peritonitis, occasionally leading to the formation of tubo-ovarian abscess (TOA). PID primarily affects young, sexually active women, and it is hig...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章,评审

    doi:10.2298/sarh1010658t

    authors: Terzić M,Kocijancić D

    更新日期:2010-09-01 00:00:00

  • Experience with lamivudine treatment for severe acute hepatitis B.

    abstract:INTRODUCTION:Experience with lamivudine treatment for acute severe hepatitis B is limited. Fulminant hepatitis develops in 1% of immunocompetent patients with acute hepatitis B. OBJECTIVE:The aim of this study was to evaluate the efficacy of lamivudine in the treatment of severe acute hepatitis B (SAHB) in immunocompe...

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    pub_type: 杂志文章

    doi:10.2298/sarh1412703v

    authors: Verhaz A

    更新日期:2014-11-01 00:00:00

  • [Orbital lymphomas].

    abstract::Lymphomas are relatively rare in the orbit: only about 8-11% of all orbital tumours. The most common histological type is diffuse well-differentiated lymphocytic lymphoma (DWDLL--Rappaport's classification)--70%. Orbital lesions are always curable by radiotherapy, but in some 40% of these patients local recurrence or ...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:

    authors: Milosević R,Suvajdzić N,Jovanović V,Latković Z,Petrović Z,Colović M

    更新日期:1992-03-01 00:00:00

  • Analysis of risk factors in the development of retinopathy of prematurity.

    abstract:INTRODUCTION:Retinopathy of prematurity (ROP) is a multifactorial disease that occurs most frequently in very small and very sick preterm infants, and it has been identified as the major cause of childhood blindness. OBJECTIVE:The aim of this study was to evaluate ROP incidence and risk factors associated with varying...

    journal_title:Srpski arhiv za celokupno lekarstvo

    pub_type: 杂志文章

    doi:

    authors: Knezević S,Stojanović N,Oros A,Savić D,Simović A,Knezević J

    更新日期:2011-07-01 00:00:00

  • Anterior and middle superior alveolar block is efficient for maxillary premolar teeth extractions regardless of the injection system or anesthetic with adrenaline used.

    abstract:Introduction:The anterior and middle superior alveolar nerve block was claimed to be unpredictably efficient for clinical application. Objective:The aim of this report was to establish the efficacy of the anterior and middle superior alveolar nerve block, applied with a computer-controlled injection system or a conven...

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    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Tomić S,Simić I,Stanojević M,Janković S,Todorović L

    更新日期:2016-09-01 00:00:00