Abstract:
:We have analyzed proteins produced in Various human gastric carcinoma cell lines and normal gastric mucosa. The production of HSP90 increased in eight gastric carcinoma cell lines. Gelsolin content was down-regulated in seven gastric carcinoma cell lines. Furthermore, the production of GST-pi increased in a poorly differentiated adenocarcinoma cell line and two scirrhous gastric carcinoma cell lines. These results suggest that increased production of HSP90 and down-regulation of gelsolin play an important role in gastric carcinogenesis, and that abundant production of GST-pi is related to unique behavior of some scirrhous gastric carcinomas.
journal_name
Int J Oncoljournal_title
International journal of oncologyauthors
Moriya S,Yanagihara K,Fujita H,Kuzumaki Ndoi
10.3892/ijo.5.6.1347subject
Has Abstractpub_date
1994-12-01 00:00:00pages
1347-51issue
6eissn
1019-6439issn
1791-2423journal_volume
5pub_type
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