当前位置： SCI文献检索 > BRITISH JOURNAL OF CLINICAL PHARMACOLOGY期刊下所有文献 > Potentially inappropriate medications in geriatric outpatients with polypharmacy: application of six sets of published explicit criteria.

Potentially inappropriate medications in geriatric outpatients with polypharmacy: application of six sets of published explicit criteria.

Abstract：

AIM:Our aim was to compare the practicability of six different potentially inappropriate medication (PIM) criteria in geriatric outpatients with polypharmacy. METHODS:We analysed baseline data from the Medication Safety Review Clinic in Taiwanese Elders (MSRC-Taiwan) study. The prevalence and correlates of PIMs were determined on the basis of criteria developed in the USA, Canada, France, Norway, Ireland and Thailand. The percentage of PIMs considered as drug-related problems and the problem-solving rate are reported. RESULTS:In the 193 participants, the prevalence of PIM varied from 24 to 73%. Application of the criteria revealed that a high number of chronic medications was a common risk factor for having at least one PIM. Of the 1713 medications reviewed, 5.6-14.8% were considered PIMs. Only 30-40% of the identified PIMs were reported as drug-related problems by the MSRC team experts. Criteria with a higher number of statements and a higher percentage of local market/institution drug availability tended to detect more PIMs. CONCLUSIONS:The prevalence of PIM varied significantly when different criteria were applied. Caution should be exercised in applying PIM criteria developed in other regions when medication availability in the local market is limited.

journal_name

Br J Clin Pharmacol

journal_title

British journal of clinical pharmacology

authors

Chang CB,Chen JH,Wen CJ,Kuo HK,Lu IS,Chiu LS,Wu SC,Chan DC

doi

10.1111/j.1365-2125.2011.04010.x

subject

Has Abstract

pub_date

2011-09-01 00:00:00

pages

482-9

issue

3

eissn

0306-5251

issn

1365-2125

journal_volume

72

pub_type

杂志文章

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