Abstract:
PURPOSE OF REVIEW:Determining which palliative interventions are appropriate within and between groups remains difficult because of the lack of prospective studies and heterogeneity in dyspnoea context, assessment and reporting. This review presents an evolution of dyspnoea theories, summarizes literature published during 2010 concerning intervention effectiveness between conditions and highlights the lag between emerging research evidence and dyspnoea assessments in clinical trials. RECENT FINDINGS:With few exceptions, first-line pharmacological agents prescribed to modify the disease with palliation of dyspnoea as consequence were unlikely to be generalizable between conditions and contexts. Two agents (supplemental oxygen in people without resting hypoxemia and benzodiazepines in advanced disease) did not significantly reduce dyspnoea. Exercise training palliated dyspnoea across conditions and contexts. Short-term reductions in dyspnoea were reported for a variety of adjunctive strategies (breathing training, electrophysical agents and psychological approaches). SUMMARY:Multiple interventions exist for palliation of dyspnoea in different contexts. The majority of studies assessed emotional and behavioural consequences of dyspnoea rather than dyspnoea sensation (intensity, sensory quality, unpleasantness). As a more detailed understanding of the mechanisms leading to perceptions of dyspnoea evolve, a 'back to basics' strategy for clinical assessment might provide a means of determining which interventions can be generalized or are best suited to various forms of dyspnoea.
journal_name
Curr Opin Support Palliat Carejournal_title
Current opinion in supportive and palliative careauthors
Williams Mdoi
10.1097/SPC.0b013e328345d4a1subject
Has Abstractpub_date
2011-06-01 00:00:00pages
92-100issue
2eissn
1751-4258issn
1751-4266journal_volume
5pub_type
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journal_title:Current opinion in supportive and palliative care
pub_type: 杂志文章,评审
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journal_title:Current opinion in supportive and palliative care
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journal_title:Current opinion in supportive and palliative care
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journal_title:Current opinion in supportive and palliative care
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journal_title:Current opinion in supportive and palliative care
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journal_title:Current opinion in supportive and palliative care
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