Management of nonmetastatic castration-resistant prostate cancer.

abstract：PURPOSE OF REVIEW:Cancer cachexia remains understudied and there are no standard treatments available despite the publication of an international consensus definition and the completion of several large phase III intervention trials in the past 6 years. In September 2015, The University of Rochester Cancer Center NCORP...

journal_title：Current opinion in supportive and palliative care

authors： Dunne RF,Mustian KM,Garcia JM,Dale W,Hayward R,Roussel B,Buschmann MM,Caan BJ,Cole CL,Fleming FJ,Chakkalakal JV,Linehan DC,Hezel AF,Mohile SG

更新日期：2017-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Cross-sectional (C-S) imaging is now commonly used to measure body composition in clinical studies. This review highlights the advantages, limitations and suggested future directions for this technique. RECENT FINDINGS:Current understanding of C-S imaging reproducibility, tissue identification and se...

journal_title：Current opinion in supportive and palliative care

authors： MacDonald AJ,Greig CA,Baracos V

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite its increasing prevalence and high mortality risk, heart failure is widely regarded as 'treatable'. Aggressive measures are employed even in its end stages. This review explores the clinical characteristics of heart failure, patterns of clinician response, and new data that may help to surmoun...

journal_title：Current opinion in supportive and palliative care

authors： Stuart B

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the psychosocial support of people affected by cancer anorexia, drawing on recent publications. RECENT FINDINGS:Recent studies describe the problem of distress in response to cancer anorexia. There are propositions of appropriate support and calls for the development of psychosocial interv...

journal_title：Current opinion in supportive and palliative care

authors： Hopkinson JB

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Patients with heart failure seem particularly suited to palliative care having needs that fall within the prototypical palliative care domains. Despite this there is still much debate as to who should respond to these needs and when. RECENT FINDINGS:Since the early 1990s many studies have been publis...

journal_title：Current opinion in supportive and palliative care

authors： O'Leary N

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:There are increasing numbers of adults with congenital heart disease (CHD) and these patients remain at long-term risk of complications and premature death. This review focuses on the changing picture of adult CHD with more complex patients surviving, the challenges of balancing life-prolonging interv...

journal_title：Current opinion in supportive and palliative care

authors： Bowater SE,Speakman JK,Thorne SA

更新日期：2013-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Developments in the management of pulmonary arterial hypertension have significantly improved prognosis changing this from an acute to a chronic disease. Despite optimal treatment many patients still have a high-symptom burden both because of the disease and the side-effects of therapy, consequently t...

journal_title：Current opinion in supportive and palliative care

authors： Gin-Sing W

更新日期：2017-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines recent literature on the psychosocial needs of and interventions for young women. We focus on the active treatment period given the toxicity of treatment, the incidence of anxiety, and depressive symptoms in these women during treatment. This review summarizes research relevant to...

journal_title：Current opinion in supportive and palliative care

authors： Fernandes-Taylor S,Adesoye T,Bloom JR

更新日期：2015-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this paper is to consolidate the literature around pain assessment and management in older adults with dementia and to make recommendations for future research and practice developments. This review is provided following the introduction of guidelines for the assessment of pain that wer...

journal_title：Current opinion in supportive and palliative care

authors： Schofield P

更新日期：2008-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss three emerging areas of research triggering new hypotheses for mechanisms of dyspnea. RECENT FINDINGS:There has been an emphasis on the importance of lung volumes in evaluating symptoms and lung function in patients with chronic obstructive pulmonary disease. Dyspnea intensity seems to mor...

journal_title：Current opinion in supportive and palliative care

authors： Rock LK,Schwartzstein RM

更新日期：2007-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the advances in trial methodology and presents new methodologies to meet some of the challenges of conducting trials in a palliative care setting. To describe why this review is timely and relevant. RECENT FINDINGS:This review discusses the process required to conduct trials of ...

journal_title：Current opinion in supportive and palliative care

authors： Davis MP,Mitchell GK

更新日期：2012-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review compares the catabolic actions of tumour necrosis factor-alpha (TNF-alpha) and proteolysis-inducing factor (PIF) and their involvement in human cancer cachexia. RECENT FINDINGS:TNF-alpha has a direct catabolic effect on skeletal muscle and adipose tissue, whereas PIF only has an effect on...

journal_title：Current opinion in supportive and palliative care

authors： Tisdale MJ

更新日期：2008-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes the role of lung volume reduction surgery (LVRS) for the management of refractory dyspnea and other debilitating conditions in patients with chronic obstructive pulmonary disease. Recent studies, including a randomized trial comparing LVRS to medical therapy, are analyzed. RECEN...

journal_title：Current opinion in supportive and palliative care

authors： Shah AA,D'Amico TA

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review summarizes recent developments in the management of gastrointestinal symptoms experienced by cancer patients and provides a framework for education, assessment and monitoring, and treatment. RECENT FINDINGS:Although many viable treatment options exist, gastrointestinal symptoms - particul...

journal_title：Current opinion in supportive and palliative care

authors： Rangwala F,Zafar SY,Abernethy AP

更新日期：2012-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Chronic breathlessness is a troublesome symptom experienced by people with advanced malignant and nonmalignant disease. Disease-directed therapies are often insufficient in the management of chronic breathlessness. Therefore, pharmacological and nonpharmacological breathlessness-specific interventions...

journal_title：Current opinion in supportive and palliative care

authors： Abdallah SJ,Jensen D,Lewthwaite H

更新日期：2019-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Palliative sedation has been the subject of intensive debate since its first appearance in 1990. In a 2010 review of palliative sedation, the following areas were identified as lacking in consensus: inconsistent terminology, its use in nonphysical suffering, the ongoing experience of distress, and con...

journal_title：Current opinion in supportive and palliative care

authors： Henry B

更新日期：2016-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Chemotherapy is a first-line treatment for many cancers; however, its use is hampered by a long list of side-effects. Gastrointestinal mucositis is a common and debilitating side-effect of anticancer therapy contributing to dose reductions, delays and cessation of treatment, greatly impacting clinical...

journal_title：Current opinion in supportive and palliative care

authors： McQuade RM,Al Thaalibi M,Nurgali K

更新日期：2020-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Highlight the difficulties patients, physicians, and the global economy face in relation to treatment of structural heart diseases. It is easy to be carried away by the excitement of medical advancement; however, it is difficult to demonstrate restraint. Transcatheter aortic valve replacement (TAVR) i...

journal_title：Current opinion in supportive and palliative care

authors： German KS,Kalra A

更新日期：2019-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Opioids are potent drugs for the treatment of severe pain, but they are burdened by detrimental side-effects, such as respiratory depression, addiction, sedation and constipation. Their clinical application is undisputed in acute (e.g. perioperative) and cancer pain, but their use in chronic nonmalign...

journal_title：Current opinion in supportive and palliative care

authors： Stein C

更新日期：2020-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews the most recent studies that examine the efficacy of psychostimulants for the relief of symptoms such as asthenia and depression in cancer patients. RECENT FINDINGS:Although most research to date has focused on the use of methylphenidate for the relief of symptoms such as astheni...

journal_title：Current opinion in supportive and palliative care

authors： Portela MA,Rubiales AS,Centeno C

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Overall survival of patients with pancreatic cancer is strongly conditioned by tumor biology and the incidence of malnutrition and metabolic disorders. In this landscape, the assessment of body composition is crucial to properly manage the clinical implications of muscle wasting. The pathogenesis of t...

journal_title：Current opinion in supportive and palliative care

authors： Basile D,Corvaja C,Caccialanza R,Aprile G

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Young women (<45 years of age) diagnosed with breast cancer face increased risk of sexual dysfunction as a result of their cancer-directed treatment. We will review the recent literature examining this critical challenge and discuss current efforts to address sexual dysfunction. RECENT FINDINGS:In th...

journal_title：Current opinion in supportive and palliative care

authors： Zhou ES,Falk SJ,Bober SL

更新日期：2015-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Many health professionals still believe that opioids shorten the lifespan of patients. This situation implies that the ethical doctrine of double effect is often invoked to justify their use in extreme circumstances. The objective of this study is to revise the evidence existing in the recently publis...

journal_title：Current opinion in supportive and palliative care

authors： López-Saca JM,Guzmán JL,Centeno C

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:AYA patients with cancer have a unique set of psychosocial and support needs to compared with their younger and older counterparts. Digital health interventions overcome many of the barriers to AYA participation in behavioral health interventions. Due to the rapid shifts in digital health, it is impor...

journal_title：Current opinion in supportive and palliative care

authors： Viola A,Panigrahi G,Devine KA

更新日期：2020-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Dyspnea is the most common symptom in interstitial lung disease, yet little is known about its management. This review summarizes the available evidence for the treatment of dyspnea in interstitial lung disease. RECENT FINDINGS:The management of dyspnea in interstitial lung disease remains a challeng...

journal_title：Current opinion in supportive and palliative care

authors： Ryerson CJ,Collard HR,Pantilat SZ

更新日期：2010-06-01 00:00:00

abstract：PURPOSE OF REVIEW:RANK ligand (RANKL) plays a central role in the cancer-induced bone destruction that results from bone metastasis. The RANKL inhibitor denosumab was recently approved for the prevention of skeletal-related events (SREs) in patients with bone metastases from solid tumors. This review summarizes recent ...

journal_title：Current opinion in supportive and palliative care

authors： Lipton A,Jacobs I

更新日期：2011-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews the status of guidelines and recommendations for communication between patients with cancer and healthcare providers (HCPs) concerning fertility issues. RECENT FINDINGS:The timing, the type of information provided, and the openness of HCPs can all affect how patients with cancer ...

journal_title：Current opinion in supportive and palliative care

authors： Shen S,Zelkowitz P,Rosberger Z

更新日期：2019-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The review is based on a Medline literature search using key words relating to male urogenital/pelvic pain for the years 2009-2011. RECENT FINDINGS:The review covers those studies relating to cause, ongoing mechanisms and treatments. SUMMARY:The review highlights that the patients are often polysymp...

journal_title：Current opinion in supportive and palliative care

authors： Baranowski AP

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The serotonergic system has long been linked to migraine but recent studies highlight how much is still unclear about this link. And recent data add to the uncertainty of where/how triptans act and why they are headache specific. RECENT FINDINGS:Markers of 5HT levels in the brains of migraine patient...

journal_title：Current opinion in supportive and palliative care

authors： Dussor G

更新日期：2014-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Recent advances in the diagnosis and treatment of many types of cancers have prolonged and improved the quality of life for cancer patients. With increased survival, metastatic spinal lesions are becoming much more of a functional and clinical problem. RECENT FINDINGS:Percutaneous vertebral augmentat...

journal_title：Current opinion in supportive and palliative care

authors： Siemionow K,Lieberman IH

更新日期：2008-09-01 00:00:00